Overview of Cell Senescence

Researchers have found that senescent cells accumulate in our body as we age. Deciphering the purpose, causes, and consequences of cellular senescence will provide us with a better understanding of the role they may play in a wide variety of diseases and how we can use therapies to remove them to improve human health.
This video is part of the Research Integrated Science Education (RISE) Program that is funded by SENS Research Foundation and Dalio Philanthropies. The program is designed to introduce high school students to aging research and laboratory concepts, such as experimental design and data interpretation, within core curriculum standards. To learn more about RISE and to access additional functionalities such as the transcript glossary function, visit www.sens.org/rise

[@nouhabhy3067]

it took me almost half an hour to write down the notes from the video.. so much information in just 5 minutes is remarkable. thank you so much

[@Itsnotmeofficer]

Can I have a copy lol

[@Itsnotmeofficer]

@nouhabhy3067 can I get a copy ?

[@stunt2flame]

Wao! Since few days I was trying to understand what are the senescence cells. This video really helped me. Easily understood with pictures. Thank you

[@yanl1352]

clear and simple, thank you!

[@luckssj]

Thanks for sharing this, very informative 👍

[@jugalpatil699]

Thank you ..very informative.

[@physiologyfun1689]

Very nice !

[@robertsmyk4102]

Is it possible that there are temporary structures such as scars, scabs and milk teeth that produce senescent cells when these transient cells complete their main purpose of repair or transition and then possibly that the SASP is the signal that their work has been completed?

[@sandrawong6787]

Alright,looks pretty cool
Is senescence the reason why trees have bark tissue too?
Perhaps senescence is an evolutionary adaptation to both prevent cancer and establish permanent structures within the body
The chemicals they release in an issue though
Once we find the genes responsible for senescence, we'll reduce the production of such chemicals and perhaps,alter it's DNA back into a stem cell so that it can repair the region

[@RodrigoOswego]

I think tree bark is specialized tissue. Senescent cells would probably explain wood better than bark. Overall, cellular senescence as it occurs in animals dosnt make sense in plants imo. once plants cells stop growing they die, right? leaves fall off and wood is dead. I dont think they can get cancer either, although mutant tumors do exist in plants if Im not mistaken. Now I want to go read about it.

[@sandrawong6787]

@@RodrigoOswego nice!
Well radiation does affect plants,mostly by killing them,there are some strange issues like spots and peculiar growth that may happen

[@ivydune4185]

But if we remove the senescent cells won't we increase the likelihood of developing cancer?

[@johnreidy2804]

Why would you say that?

[@ivydune4185]

@@johnreidy2804 I've seen some studies saying that we should not eliminate all types of senescent cells.But maybe it's nothing. Studies come and go.

[@johnreidy2804]

@@ivydune4185 Yes, but they also say that a 72 hour fast will create autophagy which helps cancer patients

[@user-pr6ed3ri2k]

Apotosis?

[@user-pr6ed3ri2k]

0:40 🥳🎉🎉 it to the 🥐

[@wb4529]

hehe

[@user-pr6ed3ri2k]

What

[@alexis-ej9sj]

Can I MLA cite a CZcams video?…. Asking for a friend

[@wenny3377]

yes js use a MLA format website and type in the url

[@christopherellis2663]

It would really help if you were to not speak American. It is very difficult for us English speakers to follow what you are saying, because we have to mentally transform it, whereupon miss what came next.

[@paulwolf3302]

Use subtitles if you can only understand your own dialect.

[@RodrigoOswego]

I hope you're joking

[@Virtual_Melatonin]

Yeah, I guess no one told you the whole world wont cope to your way of life.