Susan Wessler (UC Riverside) Part 1: Introduction to transposable elements
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- čas přidán 21. 07. 2024
- www.ibiology.org/genetics-and...
In Part 1, Wessler introduces transposable elements (TEs); small movable pieces of DNA that can insert throughout the genome. She describes their discovery in maize by Barbara McClintock in the 1940's and their impact on the current study of genetics. Wessler goes on to provide more details about TEs and transposase, the enzyme that facilitates insertion of TEs into the target DNA.
Amazingly, as much as 50% of a mammalian genome and much more of a plant genome can be made of TEs. In Part 2 of her talk, Wessler discusses work from her lab analyzing the impact of TEs on gene and genome evolution. By looking for and finding a TE currently undergoing rapid amplification, Wessler and her colleagues have been able to assess how a type of TE called a MITE can rapidly increase its copy number without killing its host, rice.
Thank you for very well explain a complicated concept.
As I am watching, questions keep coming up in my head then explained right after
This was easy to understand but interesting and informative at the same time. Thank you :)
Amazingly inspiring 🥰
Probably the best explanation on this topic.
Interestingly, retrotransposable elements not only hop around within the genome of a single cell, but it has now been shown that these strange elements can hop into extracellular vesicles called exosomes and enter the genomes of other cells! Strangely, we have a lot of intracellular defences that try to limit the expression of these strange "jumping genes", and we know they go nuts in cancer cells as well.
she is a living legend
Thank you very much for this hugely helpful lecture. It's the clearest explanation of TEs I've across.
Thank you so much! You are better than most professors I know at explaining TE and the types of TE! Much appreciation for your time.
That is absolutly amazing. Thank you very much for this awesome presentation!
Great explanation !!!
Thank you for sharing and presenting! Much appreciated!
Awesome talk. Thank you !
loved it completely. Thanks Dr Susan.
Thank you so much, I'm studying for my intro. to biology midterm and this helped a lot.
It was very useful information for me. It is at the level of graduate students level. Thanks for sharing your knowledge with other people Dr.Wessler
Amazing presentation.
This is truly amazing!
Beautifully Explained
wonderful! thank you for this brillant presentation!
I'm not in biology at all really... just really interested n Genetics becasue I'm from an IT background. Both fields have decided to get married (of sorts) rather recently after a prolonged engagement... But until this video I had never heard of Barbara McClintock... Its rare enough that someone sees something everyone else missed, rarer still when the tools to see it are not available and in 1940 nobody knew the structure of DNA ... so to be honest I'm flabbergasted she could infer so accurately from the information she had. Certainly adding this woman to my reading list.
Although looking at amazon her collected papers are a little on the steep side.... How do we expect more McClintocks to emerge if knowledge carries such a premium?
Supply and demand sets the price. Society has evolved through pioneers who sacrifice for the betterment and advancement of knowledge. The masses just go round in circles when unprovoked. It is the geniuses who make them spiral slowly upwards.
Although of course there are a lot of decent average people who provides stability for this to happen, even if they fail to contribute to real advancements.
Around 6:40 or 6:50, what does lower mobility of plant cells have to with pigmentation I didn't get it ?
This is at least as fascinating as astronomy, but considering that this is all on a submicroscopic scale, it is more fascinating to me.
I feel like I've just been awakened from a dogmatic slumber. Mind-blowing talk!
what an amazing video.
very understandable thank you!!!
19:25 How is it 5 BP ?
thank you
Thank you, my exam next sunday
Nice presentation. I am big fan of her
perfect
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i know her :D
I'm gonna leave a comment, but I'll show you in a minute what that is.
:v