We Built A Laser Out Of Tin Foil And Highlighters

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  • čas přidán 11. 05. 2024
  • Dye lasers are amazing because they are a high power source of laser light in essentially any color. And best of all you can switch colors in as long as it takes to change the liquid. Today we explore how they're made, how they work, and how a laser made of garbage could be the secret to making a meat laser.
    Get your tickets for opensauce now! opensauce.live/
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    Previous videos:
    Meatcubator • This Machine Grows Liv...
    Genetically modifying Bacteria • Simple Bacteria Geneti...
    Designing DNA • [LIVE] Learn Genetic E...
    Magnetron • Coat ANYTHING in METAL...
    Videos from other channels:
    @styropyro • DIY Laser Made from Th...
    @LesLaboratory • DIY Home made High Per...
    @PlasmaChannel • Building A Simple High...
    0:00 Introduction
    4:09 TEA lasers
    6:42 Building the Laser
    9:38 Dye lasers
    13:15 Changing colors
    14:54 Wrap up
    16:00 Opensauce
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  • Věda a technologie

Komentáře • 1,1K

  • @tkaczgames564
    @tkaczgames564 Před 11 měsíci +2119

    Stuff like this is what motivates people to become biotechnologists. Making whatever you want, playing with organisms and modern technology creating something that sounds like magic

    • @grins9882
      @grins9882 Před 11 měsíci +77

      True, this channel is the main reason I'm pursuing genetics rn

    • @UNVIRUSLETALE
      @UNVIRUSLETALE Před 11 měsíci +42

      Absolutely, I chose to do my biotech bachelor's because I wanted to know how fluorescent cats worked and I'm now halfway through my masters

    • @maxluthor6800
      @maxluthor6800 Před 11 měsíci +3

      yup same here

    • @justsomeguy5628
      @justsomeguy5628 Před 11 měsíci +15

      And the amazing thing is that all of this can actually be what your job is like, depending on the specifics. For example, a bio laser could be used in experimental cancer treatment, advanced brain scanning technology, indicators that literally point to the location, and more.

    • @monad_tcp
      @monad_tcp Před 11 měsíci +13

      Im a computing scientist and I'm disappointed we don't use more lasers.
      Where are my optoelectronics ?
      I mean, I know about photolithography which is basically how every chip is made ever.
      Still , want to play with lasers .

  • @quillclock
    @quillclock Před 11 měsíci +822

    the fact your laser made of "trash" worked better means the fates have decided you are a garbage bender now. you made too many amazing things from scrap that it's your medium now. o7 keep up the amazing work

    • @DoubsGaming
      @DoubsGaming Před 11 měsíci +25

      Welp if it means reduce, reuse, recycle then it's probably for the best right?

    • @partciudgam8478
      @partciudgam8478 Před 11 měsíci +2

      Gomi no Sensei!

    • @ViniSocramSaint
      @ViniSocramSaint Před 11 měsíci +7

      I cracked! It shouldn't be that funny "water, earth, fire, air,... garbage!"

    • @johnmarkgatti3324
      @johnmarkgatti3324 Před 11 měsíci +4

      i had a mental flash of doc from back to the future digging through the garbage for fuel too !!.

    • @bup3483
      @bup3483 Před 10 měsíci +1

      ​@@johnmarkgatti3324 Ja, Ulkig. Gut das wir wissen, das er gerne Läserstralen positiv einsetzten möchte, um Vitamine, Spurenelemente und ähnliches zu suchen.

  • @airborne0x0
    @airborne0x0 Před 11 měsíci +752

    Thanks for this. Almost 40 years ago in 8th grade I had the assignment to 'design' a biological creature. I had been obsessed with dye lasers from a library book on how to make your own (I later dug into research and Amateur Scientist articles), and imagined a creature with a biolaser built in, with a flash lamp pumped with the biology of an electric eel, with fluorescent liquid similar to a jellyfish, biolenses of a squid's eye, and partially reflective material similar to a cat's iris or the skin of some fish. The teacher was very critical and said it was so improbable. But that wasn't the assignment, and I remained convinced all this time that all the components were possible, with occasional flashes of vindication coming out, including this one. I still have the desire to build a dye laser so I will have to pop it a little higher in my project list.

    • @andrewferguson6901
      @andrewferguson6901 Před 11 měsíci +46

      Bro. You're on another level

    • @freelancer917
      @freelancer917 Před 11 měsíci +65

      Finally. Sharks with lasers.

    • @drewlop
      @drewlop Před 11 měsíci +57

      Well boo to that teacher! Sounds like you thought it through very well

    • @janthran
      @janthran Před 11 měsíci +14

      @@freelancer917 bad idea! the only reasons sharks haven't taken over the world yet is cuz they haven't got good enough guns yet!

    • @airborne0x0
      @airborne0x0 Před 11 měsíci +22

      Things will get interesting once we get to the stage where we can do fully simulated generative DNA design and program in biological components as needed. I think we have the tools to start working on this now.

  • @Nighthawkinlight
    @Nighthawkinlight Před 11 měsíci +1039

    Neat stuff! The rail laser is crazy, never seen anything like it.

    • @Dinnye01
      @Dinnye01 Před 11 měsíci +13

      It is almost surprising to me that you have not yet touched on lasers yet. Then again, that might be a job for Tech Ingredients.
      Nice to see you here!

    • @STONEDay
      @STONEDay Před 11 měsíci +26

      Last thing you'll ever see.

    • @janthran
      @janthran Před 11 měsíci +10

      seeing something that generates that much power with essentially no insulation is pretty terrifying lol

    • @Psykoses
      @Psykoses Před 11 měsíci

      Styropyro and The Plasma Channel also made their own versions of that laser. Both just as terrifying.
      Styro
      watch?v=1psxE4NlECQ
      PC
      watch?v=YFkUOPl0tUw

    • @p8p877
      @p8p877 Před 11 měsíci +5

      Styropyro made it a while ago

  • @anonimowyburek7207
    @anonimowyburek7207 Před 11 měsíci +241

    i absolutely love how you discurage from building the laser but still provide all the details "just in case"

    • @threeMetreJim
      @threeMetreJim Před 11 měsíci +13

      The 'technicalities' of the desire to transfer knowledge, while at the same time avoiding a channel/video takedown because of 'Karens' (or atmospherically geometrically frozen water).

    • @yandere8888
      @yandere8888 Před 11 měsíci +9

      @@threeMetreJim ah yes hes saying to not build the lethal insta kill/blind machine cuz hes afraid of yt taking him down

    • @johnmarkgatti3324
      @johnmarkgatti3324 Před 11 měsíci

      plus his mum said ,' don't do that ' many times ,so he is naturally programmed to have to try it , knows we are too ,human nature ..ever since Eve actually ,When the Big Boss ,said don't eat that trees fruit it will kill you , what did she jolly well go and do !!??.

    • @charlesnathansmith
      @charlesnathansmith Před 10 měsíci +8

      You can't stop people from doing dangerous things. You can show them how to minimize the risks

    • @matheusviana8056
      @matheusviana8056 Před 10 měsíci +4

      "Don't actually try this. Here's the circuit diagram of the laser..." - The Thought Emporium

  • @finnimus2547
    @finnimus2547 Před 11 měsíci +58

    this brings a whole new meaning to flesh light

    • @mikeoxmall69420
      @mikeoxmall69420 Před 10 měsíci +4

      Bro made a Scorn gun💀

    • @bup3483
      @bup3483 Před 10 měsíci

      Nicht witzig, solch Laser sollen keine Proteine usw. zerstören.

    • @darrylkinslow5613
      @darrylkinslow5613 Před 3 měsíci +1

      No, I don't think it does. How do you figure "laser" and "sex toy" are close enough to associate the name of a sex toy with a laser?

    • @wea69420
      @wea69420 Před 2 měsíci +10

      ​@@darrylkinslow5613a meat laser.
      a flesh light.

    • @kadrix732
      @kadrix732 Před 2 měsíci +7

      @@darrylkinslow5613You... Really aren't very smart, are you?

  • @mikajacobsen860
    @mikajacobsen860 Před 2 měsíci +5

    I have worked with dye lasers and want to share some insights:
    - You do not need UV light to pump Rhodamine 6G. The frequency-doubled output of a Nd:YAG laser (532 nm) is typically used and is much more efficient since the quantum defect to the emission wavelengths is small.
    - A pumped stagnant dye solution will quickly get trapped in states that are unresponsive to pump light. The dye solution is therefore typically circulated so that the dye molecules have time to return to the ground state before being pumped again.
    - The optimal dye concentration depends on the length of the cuvette with longer cuvettes needing less concentration. The concentration also shifts the tuning range of the dye with higher concentrations shifting to higher wavelengths.
    - The surfaces of the cuvette can themselves act like a laser resonator, resulting in an unwanted beam. The cuvette is typically vertically tilted to steer that beam away from the intentional one.
    - The positioning of the cylindrical focal lens is quite important as you have correctly identified. However, tilting the lens like that results in aberrations that lead to uneven illumination. A better solution would be to move the whole lens closer or farther away from the cuvette. Where the lens needs to be rotated is around the axis set by the pump beam. This tilt angles the focal line. You can either align the focal line with the laser resonator for maximum conversion efficiency or tilt it slightly away from it to limit the amount of amplified spontaneous emission that travels along with the dye laser beam.
    - Rhodamine 6G is indeed a nice dye.

  • @agentklaas
    @agentklaas Před 11 měsíci +133

    As one of my optics profs once said: almost everything will lase if you pump it hard enough.
    Also, and without getting into the intricacies of building a high end laser, a simple trick to make the laser cavity more stable (which should make it easier to align) is to replace one of the end mirrors with a slightly convex mirror (i.e. with focal length larger than your cavity length).

    • @reinei1
      @reinei1 Před 11 měsíci +23

      Yeah, creating a more stable (as in stability polynomial, not necessarily acoustically) cavity is to provide at least *some* form of focusing.
      Also for anyone else interested in doing this themselves:
      Just because the commercial UV laser was *safer* (electrically) to operate it's STILL A UV LASER which means it basically automatically is a class 3 or higher laser and also carries a higher risk of cancer (I am not entirely sure if this is wavelength dependent, but in all laser safety briefings and classes our magical wavelength is 400nm and everything below that requires *very* hard to get safety gloves and thorough documentation for something like 40 years due to the potential increase in cancer risk if exposed to the beam)

    • @jamesbachman4249
      @jamesbachman4249 Před 11 měsíci

      @@reinei1 you're right it's wavelength dependent. UV light is just the right energy level to cause particular mutations in our DNA (two bases covalently bond together), whereas visible light is too long wavelength. I'm guessing high power visible light would just burn a hole in your skin before causing cancer

    • @sciencegeek499
      @sciencegeek499 Před 11 měsíci +11

      @@reinei1 and blindness,, gotta make sure those goggles are validated correctly

    • @Mister_Brown
      @Mister_Brown Před 11 měsíci +18

      @@sciencegeek499 which is even more important with dye lasers since you can produce colors that no goggles exist for

    • @ericlotze7724
      @ericlotze7724 Před 11 měsíci +7

      @@reinei1 Electrical Interlocking and MAJOR Safety Precautions are for nerds though…
      ( /j , the people behind this channel are probably doing all that / fine, but yeah especially the diode lasers selling these days really pretend laser safety doesn’t exist)

  • @BackYardScience2000
    @BackYardScience2000 Před 11 měsíci +325

    Dude, if I had known that you needed dyes I would have sent you some of every kind that I have on hand for free. I really need to get up with you on donating some stuff one day. As a chemical distributor, I have tons of dyes, just like these, that you could just have. Take fluorescein for example, I have pounds upon pounds of the pure powder, plus tons of others. If you ever need anything like that, just let me know and I'll gladly send you a ton of each absolutely free. 😃

    • @Shrek_Has_Covid19
      @Shrek_Has_Covid19 Před 11 měsíci +43

      can you help me make methamphetamine

    • @BackYardScience2000
      @BackYardScience2000 Před 11 měsíci +33

      Thank you all for the encouraging remarks! I will reach out when I find the time to do so and I will try to donate some chemicals and elements to his channel/business to help save him some money and to just help out. Ignore the guy wanting to make drugs. I get comments like this occasionally due to some of the things that I sell and I do not appreciate those types of comments and I report any suspicious people to the feds because I am required to do so by law in order to be able to keep selling such things. Don't want to get a visit? Don't ask me to help you make drugs. Simple.

    • @Shrek_Has_Covid19
      @Shrek_Has_Covid19 Před 11 měsíci +19

      ☹️

    • @handlesarefeckinstupid
      @handlesarefeckinstupid Před 10 měsíci

      ​@@Shrek_Has_Covid19not gonna lie, that made me snort.

    • @yosemitesam9576
      @yosemitesam9576 Před 10 měsíci +9

      @@Shrek_Has_Covid19Did you actually think doing that was worth it lol

  • @dontworry4945
    @dontworry4945 Před 11 měsíci +77

    Literally synthesized molecules in an abandoned farm house for 2 years trying to make one of these dye lasers.
    And the meat laser? Way farther than i ever could achieve.
    I made 3 dyes but i could never get them into lasers. I didnt have ambition, or 3d printing but man. This was literally my dream as a 17 year old.
    Thank you for reminding me of the days of gold when chemistry channels like nurdrage and chemplayer and masterminds like styro the like Began to inspire me. You really rock, bro.

    • @Slop_Dogg
      @Slop_Dogg Před 11 měsíci +1

      Yep, this guy is seriously skilled. I was blown away

    • @commentfailedtopost
      @commentfailedtopost Před 10 měsíci

      You created life?

    • @dontworry4945
      @dontworry4945 Před 10 měsíci +1

      @@commentfailedtopost truthfully that not a impressive accomplishment. but I think you misread my comment if that's what you absorbed from it.

    • @commentfailedtopost
      @commentfailedtopost Před 10 měsíci

      @@dontworry4945 So, a whole celebrated book is devoted to the concept of creating life, in which case a monstrosity is born, but when we do it today and answer a thousands-year old question of where do we come from, we're just, like, "meh"?

    • @spvillano
      @spvillano Před 8 měsíci +2

      @@commentfailedtopost granted, I curse in 6 languages fluently and was raised speaking both UK and US English, somehow I didn't get creating life out of synthesizing molecules.
      For fuck's sake, burning hydrogen synthesizes water molecules! That sure as shit isn't life, but absolutely necessary to maintain it.
      Of course, synthesizing organic chemicals properly, that's a wee bit more complicated.

  • @storbytronics
    @storbytronics Před 11 měsíci +25

    I built one of these when I was 13 not realizing how dangerous they were, I am still surprised and thankful I did not get electrocuted or blinded doing it!

  • @uncommonsensor
    @uncommonsensor Před 11 měsíci +58

    How neat that you went over the build process in such detail

  • @Mwwwwwwwwe
    @Mwwwwwwwwe Před 11 měsíci +36

    "Then I just download the genetic sequence from 'thingiverse' and quickly insert it into e-coli"😂😂😂😂

  • @notapplicable7292
    @notapplicable7292 Před 11 měsíci +59

    It really feels like stuff is ramping up this year! Looks like the infrastructure work over the last few years is really paying off.

  • @SenpaiSkyy
    @SenpaiSkyy Před 11 měsíci +8

    Oh sweet 3D files for a dye laser. I have Been looking for this. Thank you!

  • @Lizlodude
    @Lizlodude Před 11 měsíci +11

    "I maintain a huge collection of genetically engineered E Coli" belongs in an xkcd somewhere
    Thanks to StyroPyro I immediately recognized the TEA laser and am immediately scared.
    Also that feeling of building it all proper like and it works worse than the prototype is so much feels.

  • @kenb4849
    @kenb4849 Před 11 měsíci +9

    I can only imagine what your ultimate goal could be with all of this, I suspect that a lot of this stuff has already been played with in the big labs, but the fact that you are doing it here, just proves that ingenuity and the masses can prevail. Best to you, Ken.

  • @grinreaperoftrolls7528
    @grinreaperoftrolls7528 Před 11 měsíci +38

    You single-handedly convinced me to switch from physics to biology back in 2021. Mad science is awesome!

    • @shipwreck9146
      @shipwreck9146 Před 11 měsíci +3

      I graduated in physics, but I have a general understanding of most fields of science (nerd with adhd)... Anyway, genetic stuff is literally magic to me.
      I'm still not 100% convinced that bio engineers aren't just wizards.

    • @Nah_I_Would_Plummet
      @Nah_I_Would_Plummet Před 10 měsíci

      biology is amazing but not enough for me to ever switch from physics lol

  • @stevepreskitt283
    @stevepreskitt283 Před 6 měsíci +3

    This video really takes me back about 35 years, when a friend and I puttered around with both N2 lasers and fluorescent dyes in our off time. Something that's not mentioned but should be kept in mind - Rhodamine 6G will stain *everything* you get it on, so aprons or other cover should also be worn in addition to PPE for the risks that will affect your health and not just your clothes.

  • @psiga
    @psiga Před 11 měsíci +16

    Downright kaleidoscopic rush of a video, and all of it was actual genuine examples of what amazing, beguiling thing you're working on! _No wonder_ I'm subscribed to you guys.

  • @TheWretchedOwl
    @TheWretchedOwl Před 11 měsíci +5

    “And I’m the only bio-engineer on CZcams crazy enough to try.
    That, in a nutshell, is why I subscribed in the first place 😅

  • @PossiblyABird
    @PossiblyABird Před 11 měsíci +14

    Modern science truly is amazing, can't wait for the meat laser.

  • @timng9104
    @timng9104 Před 11 měsíci +1

    great to see ur lab growing well! sputtering, meatcubator, lasing set-ups, so cool!

  • @DAVOinIN
    @DAVOinIN Před 5 měsíci +2

    I'm a laser physicist by trade and this is a fantastic video. Most of it is familiar, but i'm very impressed by how well you synthesize all these different topics and condense them without necessarily reducing them to an inaccurate form. Specifically, the topic of grating based mode-matching is awesome and a bit of a pain to explain well, but you managed to do it in less than 30s!
    One critique is that the TEA doesnt work via stimulated emission, but rather ASE (amplified spontaneous emission). This also means that although it is fairly temporally coherent, it isn't perfectly so which is why it only runs on a pulsed source.

  • @LeoDaLionEdits
    @LeoDaLionEdits Před 11 měsíci +35

    "I wouldn't recommend you building this, but here is exactly how to build it" 😂

  • @matthewphillips9083
    @matthewphillips9083 Před 11 měsíci +6

    This gives me the same vibes as writing my engineering honours project, you've clearly done tonnes of amazing work and have absolutely no time to show us the immense amount of work you had to do to get to where you are. Very interesting and exciting video, loved it!!

    • @iwanttwoscoops
      @iwanttwoscoops Před 6 měsíci +1

      i like that you used this one paragraph compliment to… brag about yourself. like your first sentence added exactly nada to the comment, and makes you look socially iffy

    • @matthewphillips9083
      @matthewphillips9083 Před 6 měsíci +1

      @@iwanttwoscoops appreciate your feedback, champ!

    • @iwanttwoscoops
      @iwanttwoscoops Před 6 měsíci

      @@matthewphillips9083 gotchu dad

  • @movax20h
    @movax20h Před 6 měsíci +2

    I discovered Les's Lab few days ago, and what he does is very impressive, but also shows how some of these things are not as complex as they might initially look. I knew of your channel for years, but this is a great showcase of lasers. The dye lasers are cool. It is also mind blowing that anybody can just engineer DNA of a bacteria with just few clicks in a browser. Wow.

  • @emyshini
    @emyshini Před 4 měsíci +1

    Loved this video. I once made a TEA laser in highschool for my science fair project. Used a neon sign transformer, some aluminum foil, painter's plastic, plexiglass, and aluminum rods to essentially make it. I wish I had access to information like this back in the day. Not that I'd know how to make these laser proteins but it would have made for a fun discussion along with how the UV laser worked and what it could be used for.

  • @kennethhicks2113
    @kennethhicks2113 Před 11 měsíci +8

    "I've done so much with so little for so long I can now do anything with nothing"
    I saw/read this many decades ago and thought I'd share in case you haven't read/heard. Very appropriate for you imo.
    Something I tell my kids and others, "There is nothing hard, just things you haven't learned yet"
    Enjoyed very much, be safe and hf learning.

  • @zenmark42
    @zenmark42 Před 11 měsíci +5

    your mad scientist projects have gotten so ambitious. this is some wild stuff man, can't wait to see how you make it work.

  • @xiaoranli8036
    @xiaoranli8036 Před 11 měsíci

    This is a crazy project. But your work is so amazing and inspiring. Good job bro!

  • @marcusramberg5340
    @marcusramberg5340 Před 11 měsíci +1

    Bro I didn’t even know you could do almost any of what you talked about, that’s super cool, like ordering custom dna things that grow with your desired codes or whatever you called it, wild man, keep it up

  • @MD-pg1fh
    @MD-pg1fh Před 11 měsíci +5

    Thinking quickly, Dave crafted a laser out of cells, a dye, and a laser!

  • @quillclock
    @quillclock Před 11 měsíci +21

    MEAT LASER!!! ok we are getting into supervillain territory. . . and i am 100% here for it

  • @-feonix48-47
    @-feonix48-47 Před 11 měsíci

    This is making me think about that silver nanoprism video from applied science a while back, and that’s one I’ve gone back to quite a few times. Great video, love this stuff as always

  • @t0nI0
    @t0nI0 Před 11 měsíci

    WHAAAT? Dude, love the synergy between disciplines and perceived simplicity you show here. That's beautiful science, I love it. Thank you.

  • @crackedemerald4930
    @crackedemerald4930 Před 11 měsíci +8

    It's weird seeing a video on such a sketchy laser machine and not be reminded how it'll delete my retina if i even think about looking at the the spot on the wall

    • @randomname4726
      @randomname4726 Před 11 měsíci +1

      "Wow! This thing is so sketchy that...... etc etc"

  • @PlasmaChannel
    @PlasmaChannel Před 11 měsíci +3

    Your nitrogen laser is a beautiful build! Far superior to mine I must say. Great video!

    • @thethoughtemporium
      @thethoughtemporium  Před 11 měsíci +1

      Thanks man! Your video was really great too!

    • @JamesBrown-oe7zd
      @JamesBrown-oe7zd Před měsícem

      @@thethoughtemporium
      Please do some experiments with a Kozyrev Mirror.
      I would really like to know the truth in what you experience.
      Apparently according to the team who work with it and others it seems to really concentrate time and the experience is horrifying to some.

  • @oxoniumgirl
    @oxoniumgirl Před 6 měsíci

    Thank you so much for posting the dye concentrations in sensible units! I'm making a rhodamine b dye laser with a SHG-YAG and the main unknown I've had trouble nailing down was how much dye to use.

  • @connorcahill8688
    @connorcahill8688 Před 8 měsíci

    So happy to see a fellow mad scientist on their way to making the potentially possible, possible. I haven’t taken any steps yet but I hope to in the next couple years

  • @aetius31
    @aetius31 Před 11 měsíci +4

    Impressive work! But don't forget to protect your skin from UV, good sunscreen is a good option if you dont want cover yourself up all the time

  • @joundii3100
    @joundii3100 Před 11 měsíci +4

    "We really don't recommend you try to build one, seriously it's super dangerous and could easily kill you in an instant. So anyway, here's exactly how you could build one."

  • @barryyoung6159
    @barryyoung6159 Před 11 měsíci

    This is absolutely awesome, thanks so much for sharing your work !

  • @SenpaiSkyy
    @SenpaiSkyy Před 11 měsíci +3

    Oh sweet a new laser video. I missed the TEA laser video you made and hid.

    • @thethoughtemporium
      @thethoughtemporium  Před 11 měsíci +4

      It wasn't very good so I wanted to redo it. This is the result. And now I have the tools to follow up and succeed on the quantum entangled particles I mentioned in that video. So really I took down 1 bad video, to replace it with with 2 good ones.

    • @SenpaiSkyy
      @SenpaiSkyy Před 11 měsíci

      @@thethoughtemporium I can't wait for the next video. Thank you for the update!

  • @gavinyarwood4752
    @gavinyarwood4752 Před 11 měsíci +3

    For the love of god please please no one ever break this man's heart.
    If he turned evil we are doomed!

  • @valiantstallion
    @valiantstallion Před 11 měsíci +1

    My lord this is an incredibly well crafted CZcams video.

  • @ExpatZ266
    @ExpatZ266 Před 2 měsíci

    So cool! I did similar a few decades back but I made my pump with plexiglass and pumped it down with a fridge pump, soooo loud and yeah, I did burn my eyes a little being in the room without full circumference sheilding on the glasses.
    Lesson kids: ALWAYS wear eye protection that coverover your eyes all the way around to the skin when playing with lasers.
    What you can't see WILL blind you if you are careless.
    Loved the vid, subscribed.

  • @DoubsGaming
    @DoubsGaming Před 11 měsíci +3

    Something I don't see anywhere which should be shouted from the rooftops. WHERE EYE PROTECTION WITH LASERS.
    Not sure if this is the type that needs it if it's a special case, but better not lose an eye.

    • @reinei1
      @reinei1 Před 11 měsíci +1

      It's a UV pulsed laser, it most definitely needs eye protection (and possibly hand protection as well, but I don't work with UV lasers because the required safety precautions are insanely difficult/costly to fulfill here)

  • @netherstarbuild
    @netherstarbuild Před 11 měsíci +3

    nice!

  • @adolfomotanavarro6553
    @adolfomotanavarro6553 Před 9 měsíci

    For the first 3+ minutes all I've been wondering about how uv tends to kill cells, good thing he did take that into consideration for the video explanation

  • @iPsychlops
    @iPsychlops Před 11 měsíci

    I am from Northern California, but this is the year that I am out of the state for my pre-doctoral internship… I am so sad that I’m going to miss seeing all of you when you would all be so close to my home. I hope you do this again!

  • @carpemkarzi
    @carpemkarzi Před 11 měsíci

    Not what I was expecting to think about today but here it is and it’s fantastic

  • @YuriChan-428
    @YuriChan-428 Před 11 měsíci

    8:34 Just look at that coronal discharge! Going from the sharp corners as they should! Beautiful!

  • @freehat2722
    @freehat2722 Před 11 měsíci

    I've been waiting many years for more work to be done on bio lasers. Thank you sir.

  • @edwardvarby4363
    @edwardvarby4363 Před 11 měsíci +1

    Back in the 90s, a guy who worked at an air force base,gave me a laser that he found in storage. some guy had made it in the 70s or 80s in his spare time from a magazine article, but one of my favorite movies was My Science Project. So I had a very high opinion of it. In this video,I recognize a lot of the parts. Mine has an watched board for the base, & plans are ancient photocopies.

  • @DirtySpoonz
    @DirtySpoonz Před 11 měsíci

    just brilliant, mad science and brilliant information delivery thanks ! keep making videos :)

  • @shortcut1331
    @shortcut1331 Před 11 měsíci

    As always super interesting content :D Thanks for sharing! :)

  • @vezenik6059
    @vezenik6059 Před 11 měsíci

    Wow, this is good. I have never thought living cells could be used for stimulated emission!
    Now I have gotta build my own!

  • @zubrkabbi
    @zubrkabbi Před 11 měsíci

    We missed your videos and mad scientist inspiration!

  • @draggonhedd
    @draggonhedd Před 2 měsíci

    I used to work in laser manufacturing and i sure do love ThorLabs. They are so fun for an industrial supply company.

  • @avi5134
    @avi5134 Před 11 měsíci

    The amount of information we get here for free boggles my mind every time.... Can't wait to see what's coming up next in the future.

  • @berylcnc
    @berylcnc Před 6 měsíci

    You guys have the secret sauce for massive technology advances - cross pollination of these vastly different disciplines. Massive love from Beryl CNC!

  • @Nobody5555-
    @Nobody5555- Před 11 měsíci +1

    love your content hope to see more soon

  • @tisAndyyy
    @tisAndyyy Před 11 měsíci

    Brilliant video. Absolutely buzzing I found your channel. It’s exactly the type of content I like to see. Keep up the great work!

  • @AIUserInterface
    @AIUserInterface Před 2 měsíci

    Wow! Thank you so much for the information. I am now a subscriber and look forward to personally going far down the laser world rabbit hole. Again, thank you so much... GL

  • @DonCarlione973
    @DonCarlione973 Před 8 měsíci

    I love stuff like this, I'm such a science nerd lol. But this is a real cool video bro, I really like what you're doing! You definitely earned another subscriber.
    Thank you for stimulating my brain!✌🏼

  • @benoit-pierredemaine3824
    @benoit-pierredemaine3824 Před 11 měsíci

    8:33 love the micro blue antennas out of the corners when it's not arcing

  • @nehemiah1441
    @nehemiah1441 Před 11 měsíci +1

    keep building from scratch I love learning form scratch. Amazing stuff!

  • @ricardasist
    @ricardasist Před 11 měsíci +1

    Bro, this was cool as heck. Keep it up, you inspired me to look for a hackerspace in my own town for a radiotelescope project, or making some graphene or making genetically modified bacteria (have no friends to do them with so i am waiting for the day i finally decide to try something)

  • @layheeee3782
    @layheeee3782 Před 11 měsíci

    I wish styropyro helped you out with this, would have been the colab of the century

  • @user-lu1pn6to9e
    @user-lu1pn6to9e Před 2 měsíci

    I believe this man's work will bring forth some good discoveries one day

  • @billykidman2091
    @billykidman2091 Před 9 měsíci

    Better watch out, Styropyro might come looking for you with the laser bazooka

  • @Financeification
    @Financeification Před 11 měsíci

    Man, I love this guy's videos. I wish I grew up nextdoor.

  • @benjaminbirdsey6874
    @benjaminbirdsey6874 Před 11 měsíci

    This is interesting. I worked with a 1-watt CW laser that used Rhodamine 6G. My first thought about using a more complex molecule is that more of the light will be trapped in states that are not optically connected to the ground state. A solution to this for dye lasers is to circulate the dye at a fast rate to keep the dye exposed to the pumping laser "fresh."

  • @user-yr7xi1om3h
    @user-yr7xi1om3h Před 4 měsíci

    I spoke to the scientist that created Glo- fish and ive been wanting to learn more about different proteins from jellyfish and other specimens. I never considered they could be made into a laser 😂. Love this channel already.

  • @serloinz
    @serloinz Před 6 měsíci

    watching stuff like this makes me realize how much of my life i have let go by without having my childhood want to build things and experiment ..life isn't over tho.. inspiring :)

  • @KalijahAnderson
    @KalijahAnderson Před 2 měsíci

    First video I've seen from you. Fascinating stuff. Subbed.

  • @npiper
    @npiper Před 11 měsíci +2

    Quick reminder that 20-ish years ago nearly everyone had a 20,000 volt flyback transformer just a few feet away from them protected from touch by just a few millimeters of plastic. I am of course talking about CRT televisions and in case you are wondering YES people did die poking around in them with screwdrivers.

  • @Midnightmicroscope
    @Midnightmicroscope Před 11 měsíci

    I was so excited to see this video! as someone who is a big fan of you and Les’ lab and as someone who happens to have a few vials of purified GFP laying around, I have wondered about this exact idea. I am so excited by the idea of you trying it for real! I hope to see you at OpenSauce.

  • @firstmkb
    @firstmkb Před 11 měsíci

    I came to a dead stop at “huge collection of genetically engineered E. coli.”
    To a guy with thousands of books, parts for obsolete computer architectures, and a ton of other random stuff “too good to throw away,” that seems weird.
    Yet you did something with it. I’m envious.

  • @thomasrogers8239
    @thomasrogers8239 Před 11 měsíci

    OMG! This is the thing! I suggested this back when the pandemic started!

  • @SadeN_0
    @SadeN_0 Před 11 měsíci

    I can't begin to imagine how many watchlists you're on, but I appreciate the work

  • @johnclavis
    @johnclavis Před 11 měsíci

    Lasers of diverse colors is beautiful and exciting

  • @tanchienhao
    @tanchienhao Před 11 měsíci

    Am very pleasantly surprised you made a video on rhodamine 6G as I’ve been looking at it for a while now

  • @PilotPlater
    @PilotPlater Před 11 měsíci

    I’m definitely not going to do this, but if I wanted to this video would be a godsend. Well done

  • @Firesgone
    @Firesgone Před 11 měsíci

    Something I am slowly becoming obsessed with is a true blue feathered chicken.
    I think I have found the right person.
    I will probably send you an email about this project for advice in the next year when I get more set up for this experiment!

  • @serta5727
    @serta5727 Před 11 měsíci

    Even thinking about this stuff is out of this world ^^

  • @colosine
    @colosine Před 7 měsíci

    You know you're working with power when the device messes with the cameras ability to record

  • @alexandrevaliquette3883
    @alexandrevaliquette3883 Před 4 měsíci

    It so nice to see such high quality DIY content.
    I'm jealous on so many level!!!
    Love from Montréal

  • @BenFortner
    @BenFortner Před 11 měsíci

    No period on the T.E.A acronym graphic. This isn't critical feedback, just a very relatable moment. Addicted to your channel now. Thank you!

  • @NurdRage
    @NurdRage Před 11 měsíci +1

    Damn that's amazing, those colors are so beautiful. I miss my days in the spectrometry lab. Looking forward to when you can sear your initials into meat with... umm... meat. :)

  • @bradmitchell5217
    @bradmitchell5217 Před 11 měsíci

    Loved this so much!!!

  • @christopherjones7191
    @christopherjones7191 Před měsícem

    A term that might be useful for adjustment is a micrometer screw, thimble or similar. A very smooth, precise piece of machenery for relatively cheap.

  • @larrysal8866
    @larrysal8866 Před 11 měsíci +1

    He has (finally) gone completely insane.
    Good

  • @ctcheath7238
    @ctcheath7238 Před 11 měsíci

    I would really love to see all those mad scientist creators collaborate on one project just to see what did they create

  • @pyro-millie5533
    @pyro-millie5533 Před 10 měsíci

    Dude, I stick to the electrical/mechanical device side of biotechnology, and Damn you make me proud of my field! Fully channeling “knows enough about electricity to be incredibly dangerous” with that trash laser lol! That’s so cool!!!!
    You make tissue engineering topics so freaking cool and approachable, even to me, on the “opposite” side of the field, who never wants to touch wet lab stuff personally because of the “breathe wrong and its contaminated and your cells are dead” aspect, but very highly respects those who work with it and advance the technology! (Also I had no clue you can just order custom plasmids and/or dna segments to splice into your cell lines now! That’s Badass!!)
    I’m gonna be following your channel super closely! This is hardcore mad science!

  • @ericlotze7724
    @ericlotze7724 Před 11 měsíci +1

    It will probably be covered in that next video, but I’m intrigued by the Dye from E. Coli at that Makerspace scale.
    Dye lasers are cool and all, but applying that to other uses of florescent dye (Microscopy Stains, Art, Non-Destructive Testing, etc) would be neat, especially with like how you said it being cheap.

    • @ericlotze7724
      @ericlotze7724 Před 11 měsíci +1

      I’m intrigued as to your methodology. I’m guessing column chromotography? If I remember correctly that is what the company Gabriel Lienca mentioned that makes blue dye from algae uses.
      Although if you can extract it with something less intense that is always a food thing.
      (Although i would love to have you design an Open Source Continuous HPLC System…)

  • @whendricso
    @whendricso Před 11 měsíci

    "Meat Laser" might be the coolest/weirdest idea I've seen on CZcams. And there is a lot of cool and weird stuff on CZcams.

  • @tulsatrash
    @tulsatrash Před 11 měsíci +1

    What a refreshing beacon of hope, rigor, and whimsy.

    • @oscargr_
      @oscargr_ Před 11 měsíci

      You mean "bacon" of hope, I think.😅

  • @guillermocontreras6945
    @guillermocontreras6945 Před 8 měsíci

    Can you make a video showing how you built those bioreactors using beakers and 3D printed parts?