First Alzheimer's patient treated with focused ultrasound to open the blood-brain barrier
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- čas přidán 1. 05. 2017
- Sunnybrook scientists have made history as they used focused ultrasound to safely and non-invasively breach the blood-brain barrier temporarily in patients with Alzheimer’s disease in a clinical trial. Read more: sunnybrook.ca/news/alz
- Věda a technologie
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Alzheimer's is a cruel sad disease.
My 93 years old Grandfather is 60% fine with this treatment,
hello dear, there is a therapy which is called "cupping" its an islamic procedure, but now a days its been doing all over the world. In this process the doctor uses a cup which sucks the clotted blood from the specific area like if you are using it on your head. It will suck all your clot blood from the head. Its a painless process of 20 mins, and after 5 to 8 sessions. All the clotted blood drain from that cup and the blood starts flows all over the veins in brain.
DSG my grandpa who used to be 270 pounds went to 80 pounds and just a few weeks and lost how to talk and swallow so and passed away on April 3 2019
As exciting as this is, the first Alzheimer's focused ultrasound video I saw showed Alzheimer's plaque in mice being broken down by the ultrasound alone. One of the exciting aspects was that it didn't need drugs. But even then it was hard to imagine -this day in age- such a treatment moving forward without drugs. Focused ultrasound has been FDA approved for treatment of many different ailments, including fibroids in the U.S since the early 2000's. Can someone explain why we need years of experiments before a patient with a disease which is always fatal can be treated? If a person were drowning, would you refuse to throw them a life ring because you are afraid they might be allergic to the life ring material? No, you'd throw it to them. Anything else would be cruel.
Hi Michele - Thanks for getting in touch. Clinical trials like this one are an important first step in determining the feasibility and safety of potential new treatments for patients. If you’d like to learn more about this trial specifically, you can find information here: sunnybrook.ca/content/?page=blood-brain-barrier-alzheimers-disease
How did you cross out the type in your comment? I'm sorry if this is off topic but I don't know how you did that.
Good point. ALZ is a death sentence. What are we waiting on?
My 93 years old Grandfather is 60% fine with this treatment,
hello dear, there is a therapy which is called "cupping" its an islamic procedure, but now a days its been doing all over the world. In this process the doctor uses a cup which sucks the clotted blood from the specific area like if you are using it on your head. It will suck all your clot blood from the head. Its a painless process of 20 mins, and after 5 to 8 sessions. All the clotted blood drain from that cup and the blood starts flows all over the veins in brain.
@@SunnybrookHospital My 93 years old Grandfather is 60% fine with this treatment,
hello dear, there is a therapy which is called "cupping" its an islamic procedure, but now a days its been doing all over the world. In this process the doctor uses a cup which sucks the clotted blood from the specific area like if you are using it on your head. It will suck all your clot blood from the head. Its a painless process of 20 mins, and after 5 to 8 sessions. All the clotted blood drain from that cup and the blood starts flows all over the veins in brain.
Canada has amazing scientists, doctors, and hospitals.
Do they have a treatment for ALZ or dementia they are working on?
@@yaimavol no but we got a bunch of pot if you wanna smoke some?
There is usually a very long waiting period before you can see a specialist. I mean LONG!
Alzheimer's treatments and medicines are far too slowly to come to market.
My 93 years old Grandfather is 60% fine with this treatment,
hello dear, there is a therapy which is called "cupping" its an islamic procedure, but now a days its been doing all over the world. In this process the doctor uses a cup which sucks the clotted blood from the specific area like if you are using it on your head. It will suck all your clot blood from the head. Its a painless process of 20 mins, and after 5 to 8 sessions. All the clotted blood drain from that cup and the blood starts flows all over the veins in brain.
@@omaraamir0333 pls how do I use it.. Do I cut the head for blood to come out?? Thanks
I know how to deal with alzheimer, my 93 years grandfather is now 60% fine. Thanks to Almighty
Omar Aamir
That is wonderful!
How has your grandfather's Brain improved??
@@patriciasullivan1775 hello dear, there is a therapy which is called "cupping" its an islamic procedure, but now a days its been doing all over the world. In this process the doctor uses a cup which sucks the clotted blood from the specific area like if you are using it on your head. It will suck all your clot blood from the head. Its a painless process of 20 mins, and after 5 to 8 sessions. All the clotted blood drain from that cup and the blood starts flows all over the veins in brain.
@@patriciasullivan1775 by google,
The suction and negative pressure provided by cupping can loosen muscles, encourage blood flow, and sedate the nervous system (which makes it an excellent treatment for high blood pressure). Cupping is used to relieve back and neck pains, stiff muscles, anxiety, fatigue, migraines, rheumatism, and even cellulite.
@@omaraamir0333 hijama??? i didnt think of this , thank you omar! i will try it for my parent
@@faebalina7786 are your parent is okk now?
My nan died from this disease. and now my pop is dying from it too. it is already to late to do this on my pop but for other patients who are just getting it need to be saved!
Firstly your efforts are appreciated I just wish this sort of thing would be available sooner from first successful trial to finally being available as a treatment.
Wish they could help my brother 🙏
So why aren’t they curing others? This is crazy
Pros and cons of a Socialist med system
@@purdakan so is this efficace ? 🧡🧡🧡 I'm sooo happy for patients 😭😭😭😭😭
Nice, hope it completes all its trials phases.
It will but lets say it doesnt
Outstanding and unbelievable result and technology.
Sadly, the canadian medical system doesn't allow for paying patients. Numerous AD patients in our country are left out to pasture ; they never received this treatment ( even those who can afford to pay for it). The very first commercial HIFU machine ( the Sonablate 200) was developed by Focus Surgery, Inc. Milipitas, CA somewhere in the early 90s and now breakthroughs are showing up , but since the inception of this biotech many have retired, have money but also have developed AD ! are they to travel overseas ? can't they be paying patients in their own country ? please correct me if I'm wrong.
Please help me find someone offering this treatment in the United States in 2024: whether part of a study, some random GP at this point will try anywhere.
Could this method be combined with a Nanoparticle mechanism? For example, the first method could be used to open the BBB and the Nanoparticles might provide greater precision when dealing with such conditions. The University of Boston has also used an approach using Nanoparticles for this very thing
Ultrasound can treat alzheimer's even without opening the blood brain barrier. There are research papers available on it.
@@Corteum I think I read that without adding drugs, ultrasound worked because the body's own immune system invade the brain and attack the plaques. That is, it wasn't the mechanical effect of the ultrasound on the plaques, but it was migrating components of blood that did the job. Can anyone confirm that?
Also, can anyone give us a rough estimate of how many years it will be before we see the treatment readily available? I would guess be five to ten, because
- there's already been success with mice
- the safety test on humans has gone well
- we might guess that 'money is no object' now because of the monster global cost of existing Alzheimer's
- enormous public motivation to eliminate the disease
- abundant volunteers for research
- the comparative risk of the procedure seems trivial compared with the cost of advancing Alzheimer's
- the cost of the procedure would probably be a few hundred dollars rather than thousands
@@BruceThomson Try here: www.fusfoundation.org/diseases-and-conditions/neurological/alzheimers-disease
Excerpt: "focused ultrasound and microbubbles alone (no antibodies) have had similar effects in two different Alzheimer’s models."
My grandma has had Alzheimer’s since I was born so I never really new her
Peyton B Byers Adams with my grandpa passed away a week ago
Quickly pls we can't wait
Glad to see this reporting, but they didn't say if Rick was doing better afterwards with medication now reaching his brain more. Or was the whole objective was to see if it can be done and not necessarily if the patient would improve?
Thanks for watching! The goal of this trial is to investigate whether we can successfully and safely open the blood-brain barrier in people with mild/moderate stage Alzheimer’s Disease. There are no medications or antibodies being administered with this trial.
Since this video was produced, we have launched Phase 2a of the trial, which you can learn about here: sunnybrook.ca/content/?page=blood-brain-barrier-alzheimers-disease
Are there any updates on this technique? Could it be used for advanced patients?
Hi there! This clinical trial is still ongoing, and is currently investigating whether the blood-brain barrier (BBB) can be successfully and safely opened using MRI-guided focused ultrasound in multiple regions of the brain, in individuals who have been diagnosed with mild to moderate Alzheimer’s disease (AD). More information can be found here: sunnybrook.ca/content/?page=blood-brain-barrier-alzheimers-disease
Dear sir i am alzheimer disease patient.where is your hospital i want that i continue my cure from your hospital. Saifullah khan from pakistan.
How do I get them to help my grandma my grandpa would pay any price to save her plz
You could buy a book title the end of alzheimer's by dr dale bresden and dr. Rangan chatterjee $20 from Amazon good luck and god bless please share
My snap chat is space.grass420 if u wanna talk
is there any side effects? using ultrasound to move and opening BBB?
Thanks for watching, Anna! Opening the blood-brain-barrier using focused ultrasound in patients with Alzheimer's disease is a safe procedure, and was deemed so by researchers in 2018 (sunnybrook.ca/media/item.asp?i=1780).
With focused ultrasound, as with any clinical trial or medical procedure, there are potential side effects that a patient may experience. The most common side effects are relatively minor, and include headaches or discomfort from lying in the MRI scanner. Fortunately, serious side effects, such as infection and injury to the brain, are exceedingly rare. Researchers have found the procedure to be well tolerated and safe, and most patients go home within hours of the procedure, or the following morning.
You can learn more about focused ultrasound at Sunnybrook at sunnybrook.ca/focusedultrasound
Take care!
Can my dad be a candidate please.
Hi James - for more information about our focused ultrasound research, including how to participate in clinical trials, please visit our website: sunnybrook.ca/focusedultrasound
I'm guessing most of alzheimer's patients will have to wait a few hundred years for this.