Are Statins a Waste of Time?
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- čas přidán 30. 05. 2024
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I've asked this many times and I'll ask it again: If inflammation is the issue, why on earth are doctors not prescribing more benign anti-inflammatories like turmeric, etc. that don't have the bad side effects of statins?
There's no money in that diagnosis! Most diseases are associated with inflammation in your body, so as you know anything natural that reduces inflammation is a good thing!
If the intention is to reduce inflammation, then you are right, curcumin supplementation is known to lower TNF-α, IL-6, IL-8, which is one of the secondary effects of a Statin.
I have zero side effects.
turmeric has oxylates
@jaysalbhatt2501 Yes, turmeric can contain a significant amount of oxalate, which can form calcium oxalate kidney stones (the most common type of kidney stone). However, some curcumin products (which are extracts of turmeric) contain little to no oxalate.
I'm a 71 year old male and my LDL increased as I moved to a Low Carb diet. My PC prescribed a statin but all other numbers/ratios are somewhere between good and great, including weight and also feel very good. I cannot bring myself to fill the prescription because of the side effects. It's not about money, the problem is that nobody has explained in a convincing manner how my life will get better or longer if I take the statin; sorry doc, this video didn't convince me either. It seems like there are only downsides and not many upsides.
Generic statins are subject to the same campaign as early treatment options for COVID. Why? To support the business plan for more profitable stents, surgery, cardiac rehab, more expensive alternative patented drugs and supplements that can be substituted with knowledge and careful measurmement of response. Just throwing the latest "secret formula" at the problem can be just as foolish as believing all pharma claims. The best answer: Focus in insulin resistance driven by sugar and starch, Vitamin D >60 , lower dose rosuvastatin and MEASURE inflammatory markers, CIMT and triglycerides with more zeal than LDL
I agree, don't fall into the medical-pharmaceutical trp. I would say not only the side effects, but for starters you have to ask is it doing any good. There are some excellent studies that say lowering LDL is a false target, and in fact, that your optimal LDL may be in the 130-150 range. So, the blood test cutoff is way too low.
ldl increasing doesnt mean anything. A recent study of lean mass hyper responders who went on a keto diet showed very high ldl with zero arterial plaque.
the demonization of cholesterol is pseudoscience.
The purpose of non-oxidized LDL is our body's natural defense against inflammation. Statins decrease the production of non-oxidized LDL, and does not decrease oxidized LDL, which is the true issue with plaque. The Texas Heart Association study shows that Statins are ineffective against oxidized LDL, the culprit of plaque. I will not submit myself to removing the body's natural defense mechanism against inflammation and opt for Statins which do not show any true benefit outside of the claims of the drug maker's assertions. Period. Life expectancy of LDL levels of 70 or less double the mortality rate of those who's LDL is 130. Full stop...
That perfectly sums up what I have been learning. Well said.
You nailed it. This is exactly what the research is saying. The medical-pharmaceutical industry has gone off the deep end.
Statins have too many side-effects. Edema was the reason my cardiologist took me off of them, plus my numbers were fine without them.
Stains fail to mitigate cardio-inflammation :: they cut it by such a negligible, meaningless, slight, tiny, minuscule amount for just such a short window of time that it is '''fraudulent''' to claim this. !!!!!
I started 5 mg Rosuvastatin and thought I was doing fine other than mildly decreased performance in the gym.
Fast forward 6 months - rechecked A1c - it had gone from 5.4 (which it had been for years) to 5.7!!! Doctor reassured me it was normal and to “stay the course” - but I wasn’t about to sacrifice my metabolic health - who knows how high it would have risen…
Was you able to stop the statins ?
@@Angie31646 I did. Just retested labs and will be discussing Livalo with my doctor - but still undecided if I’ll restart a statin after that experience and the recent NEJM review. My inflammatory markers are all already very low so not sure statin side effects are worth the benefit
I had the same issue and stopped taking my statin.
Rosuvastatin will push you into full blown DMII over time. Your A1c was very good and it crept up on the Crestor. Your doc knows he or she has wiggle room, and when the A1c gets too high, it might be too late.
Well my LDL went from 127 to 47 in 5 weeks.....for sure not possible without satins. Was ordered rosuvastatin 5mg/ezetimibe 10mg ones a day due to soft plague finding(zero in calcium score). No change in BMI, still 24. I simultaneously started paying serious attention to carbohydrates intake, changed the focus from low fat to lower carbs. Pretty sure have a insulin resistance issue, despite no basic labs is showing it. Pretty sure the doctor want me to continue as is, my own plan is to now take these only every second day, but still continue with the changes in my diet( for rest of life).
So if you have have high cholesterol with low levels of inflammation without using a statin then why would you take a statin?
That scenario is why many in the keto and carnivore circles feel a statin is not necessary despite high cholesterol
@@drumsnmore2545 That's why I prefer to avoid keto or carnivore. I've tried extended fasting, which produces the same ketosis benefits that a keto diet produces. I can't say that a keto diet doesn't work, but it requires strict observance. You have to monitor your ketones to do it effectively, because when you exceed your carbs and throw your body out of ketosis, you then have all the bad effects of animal proteins and fats with none of the corresponding benefits of being in ketosis.
Heart attack in 2012 @ age 53, 5 stents later & various meds, including - 80mg Atorvastatin CA daily for 11+ yrs now. ZERO side effects. I also try and consume natural anti-inflammatory foodstuffs as much as possible.
Year 2005. My CT Angio showed 60% occlusion of my. LAD. That was up from 30-40% occlusion from CT Angio before. I reduced Saturated Fats to minimum after that 60%. Focused on 60-60-60 plan of Track Your Plaque by Dr. Davis at that time. He limited Saturated Fats to 20 grams a day. I been on Lipitor 80 since 2005. No side effects. Knock on Wood. Today no stents or Heart Operation. Knock on Wood. Had to DO many things to get HDL 60mg/dl. LDL 60mg/dl. TG 60mg/dl. I also tested my lipids with LipoScience NMR. I also tested Lipids with Berkeley Heart Lab.
@@larrywong7834 The typical centenarian that has not died form cancer or heart attack yet has an average LDL cholesterol of about 107 mg/dL.
Tried several statins over last 10 yrs. At dosage prescribed it was untenable, cramps, brain-fog, larthagy, muscle aches to name a few side-a. I'd rather cut out meat, sugar & go manic on exercise than suffer statins.
Would you please do a poll were people can tick one of 3 boxes say. Statins i took were 1)Good for me 2)Not so good 3)Horrible for me / something like that, thanks.
#2 Not good for me. Became bed ridden
Side effects are not worth it.
Stains fail to mitigate cardio-inflammation :: they cut it by such a negligible, meaningless, slight, tiny, minuscule amount for just such a short window of time that it is '''fraudulent''' to claim this. !!!!!
This is CYA. What one always hears is your LDL is high so I am prescribing a statin. You never hear that some inflammatory markers (which ones?) are high and therefore I am prescribing a statin. Further, your doctor then determines how well the statin is working by assessing your reduction in LDL! And all the research focuses on the "success" of statins in reducing LDL. So, all of a sudden the medical establishment wants to say it never was about LDL; it's about inflammation. LOL.
Ive had same cardiologist for three years and he has yet to check my creactive protein nor an NMR type LDL test
I had very bad side effects from a statin, after my cardiologist assured me that there were NO side effects. I am afraid of statins now. Until medicine acknowledges the reality of statin side effects, I will not hear anything on the subject.
Every prescription drug or any over the counter meds have side effects, that was definitely a red flag!
What is the best dosage of statin to use in that case?
The nocebo effect, the inverse of the placebo effect, is a well-established phenomenon that is under-appreciated in cardiovascular medicine. It refers to adverse events, usually purely subjective, that result from expectations of harm from a drug, placebo, other therapeutic intervention or a nonmedical situation. These expectations can be driven by many factors including the informed consent form in a clinical trial, warnings about adverse effects communicated by clinicians when prescribing a drug, and information in the media about the dangers of certain treatments. The nocebo effect is the best explanation for the high rate of muscle and other symptoms attributed to statins in observational studies and clinical practice, but not in randomized controlled trials, where muscle symptoms, and rates of discontinuation due to any adverse event, are generally similar in the statin and placebo groups.
I'm not sure I believe these nocebo studies, as they are usually performed by the drug companies themselves. These companies are notorious for doing 5 or 10 studies, finding adverse effects in every study except one, and then publishing only the one study which demonstrates the results they want.
@jft8994 Individuals who are metabolically healthy, should strongly consider the way in which big-pharma plays the numbers game, in that, they reveal benefits of Statins in terms of relative risk, and then turn right around and use absolute risk numbers in the area of side effects of Statins. If someone is not metabolically healthy, like those who are diabetic for example, have a much greater risk from inflammation than those who are not diabetic, and leads to greater risk of heart related failures. So careful examination of A1C and ApoB is some critical markers to help one determine a better course of action than simply "your LDL is over 100, so we're placing you on Statins..." I invite you to go and listen to "STATINS - EMPEROR HAS NO CLOTHES - Dr Nadir Ali" and "What High Cholesterol Does To You | Dr. Shawn Baker & David Diamond, Ph.D."
@@deltabravo5507 I don't see the relevance with my post but I will take the bait.
I know all of them. Any removal of one of the three major food elements is not healthy on the long run. America food industry has created the most obese people in the world, junk eaters , couch potatoes and offered them dumb diets to lose weight. If you see cardio doctors in Europe, they will recommend a balanced diet like the Mediterranean. No carnivore or keto stuff. Japanese and French people have the lowest heart issues , eating rice, bread, pasta and more. They don't feed on processed food, don't pig out, walk far more. If keto is a crutch for fat people with carb cravings, good for them. I watched Ali's video on lp(a), he is wrong in interpretating the numbers of French centenaries with high lp(a). Statins have been over-prescribed for sure but when your Apo(B) is 100 or more, your lp(a) over 100, or a CAC over 100, statins are a must. Can't tolerate them? Go with Ezetimibe, PCSK9.
@jft8994 I think you completely missed the point of my post. You're arguing diet, I'm stating methods of screening used by many cardiologists, including my own right before I fired him, and certainly the way in which big-pharma has strong-armed the medical industry. Each individual's metabolism profile is much more complex than simply determining location as the criteria, or one diet over another with such a broad and superficial brush. And while I realize that eating junk food only can be detrimental, but such attitudes like vegan only presents it's own issues for some. I prefer whole foods. Vitamin B3 is just as effective in lowering cholesterol, and was the go-to solution before Statins came around, (however B3 is not as profitable for big-pharma) and do not pose double the occurrence of early onset dementia like Lipophilic Statins. Information concerning Statins over the last few years should give anyone pause before even considering its use. Cholesterol isn't the issue here. Lower carb diets equate to lower HbA1C levels, which in turn, equates to lower CAC scores. (Journal of the American College of Cardiology - Glycated Hemoglobin and Subclinical Atherosclerosis in People Without Diabetes)
Dietary Cholesterol and Cardiovascular Risk: A Science Advisory From the American Heart Association - "Previously, the Dietary Guidelines for Americans recommended that cholesterol intake be limited to no more than 300 milligrams per day. The 2015 DGAC [Dietary Guidelines Advisory Committee] will not bring forward this recommendation because available evidence shows no appreciable relationship between consumption of dietary cholesterol and serum cholesterol, consistent with the conclusions of the AHA/ACC report. Cholesterol is not a nutrient of concern for overconsumption"
Metformin disadvantages, anti health :
leads to significant reduction in testosterone levels
ED,
Impairs exercise benefit, Impairs muscle gain
My Alt and Ast were elevated after 30 days of statin 20mg! Please explain!
I'm curious about the marijuana-inflammation discussion they must have been having before editing out this video.
Same here. I used to smoke a lot before heart attack to be honest
Yes.
It should be illegal to advertise efficacy as “relative risk”. All risk reduction should be “absolute risk reduction.” Does a 1% benefit with significant risk of serious side effects sound reasonable to you? The medical profession should be ashamed of themselves for promoting this nonsense.
You also have to do the math in the opposite direction in order to be fair. A 1% absolute risk reduction of having a heart attack in the next year translates into a 10% absolute risk reduction of having a heart attack over the next 10 years, or 20% over the next 20 years.
@@JustMe-vn5pqThe 1% ARR is already over 10 years!
Tried them on low dosage and I was literally crippled
So Statins lower Inflammation so therefore if a person has a large amount of plaque in their carotid would statins help lower inflammation and therefore decrease the risk of a stroke due to a heavily blocked carotid which has not reached the point for surgery yet?
Lowering inflammation, as measured by a CRP blood test (C reactive protein) will certainly help. Turmeric works better to do this than statins do. I've got some plaque in my coronary arteries, and so I'll be monitoring it by undergoing yearly CIMT scans. It's critical for both you and me to do whatever is necessary to keep that plaque from getting worse. I haven't ruled statins out yet, but I prefer to try natural methods first to see if I can get my worrisome numbers moving in the right direction without statins.
Wait... Weed is not good for CV health??? How???
I had a CRAO of my eye one month ago, I have a good diet and exercise. I was on low dose crestor and baby aspirin and had minimal side effects. now after my eye stroke I am on 40mg of statin and 75mg 0f plavix plus baby aspirin and I feel horrible. My LDL is 79. I cant stay on this dose much longer, my neurologist was surprised of the dosage. I am afraid my other eye may get a stroke someday, ANY SUGGESTIONS from experience.
Make sure your neurologist checks the carotid arteries. Plagues that break off can cause CRAO. Im sure they would do this. Also control hypertension if that’s an issue. Follow up with a retinal specialist.
I have 10mg rosuvastatin, cut it into 1/4, take it maybe every other night. Don't know if it's good, but no side effects. I have close to zero plaque in arteries. Good cholesterol ratios.
I do have some plaque in my coronary arteries, as measured by a CAC scan. My total cholesterol is just under 200, which isn't bad. However, I'd rather find a diet that works (maybe a vegan diet with almost no processed food?) to lower my total cholesterol down to 150 without statins. At that low level, a heart attack is virtually impossible. I'll also be monitoring my plaque with yearly CIMT scans. I'm already taking turmeric, K2, and nattokinase, but all those supplements do is keep the problem from getting worse. The vegan diet might also lower my weight, which is a major concern since my BMI is 27 or 28.
Cardiologist Nadir Ali has a youtube video dedicated to Statin Research Studies. Pretty Clear all cause mortality is changed little by the use of statins. So are all the under reported side effects really worth it?
The New England Journal of Medicine just did a huge meta analysis looking at 1.5 million participants and found the same thing - statins had no effect on all cause mortality (they DID have a modest effect on CV disease)
Could you please share the title of the particular video of Dr. Ali that you mentioned above? I would like to watch.
@@drumsnmore2545 By searching the NEJM for statins and all cause mortality, they said that statins DID lower all cause mortality (though they increased the risk of diabetes). However, the beneficial effect of statins was far greater for: 1) patients at high risk of a CV event, especially people who've already had a heart attack, or 2) patients with a high rate of inflammation, as measured by a CRP test. So if you lower your inflammation with something safer and more effective like turmeric, then the benefits of statins are marginal, unless you're at high risk of a CV event.
@@JustMe-vn5pq If you look at the very recent “Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality” you’ll see statins did not reduce all cause mortality - only CVE risk. Not that that isn’t significant - the lingering effect of stroke can be awful if the patient survives - but in the end - at least in this comprehensive analysis - all cause mortality was not affected by a statin
@@drumsnmore2545 I finally did gain access to the study, and you were right. According to their charts, the ideal LDL number for preventing CV disease is 120, but a higher LDL number of 170 is ideal if my only goal is to reduce my risk of death. Mine's just under 140, which means that if I were to take a statin and lower it still further, I'd just be likely to die more quickly.
I’ve not had a single side effect. Maybe some have more sensitivities to them
If it's only inflammation aren't there plenty of alternatives to statins?
how do statins lower inflimation.. your the only doctor that thinks this ..any data on that??
The anti-statin book called The Cholesterol Myth says that statins do lower inflammation, at least a little bit. I trust that source. But I'll find another and better way to reduce my inflammation than by using statins.
If you have CAC 500 to 1000 agastons WHATs been PROVEN to reduce arterial Inflammation to significantly reduce Soft Plaque. So that Heart Events is at a Low Level.
My CAC score is something around 290 (a zero score is perfect). I put this into one of those heart disease risk calculators, and it told me that this CAC score means that I have 80 year old arteries in a 72 year old body. Therefore, I MUST find a way to lower my plaque. I'll be monitoring my plaque with yearly CIMT scans to see if I'm successful or not.
@@JustMe-vn5pq I don't have my CAC Scans in front of me right now from Budoff. But believe it was around 800 agastons back in year 2006. I was back then like age 58.
Are there foods or supplements that are as effective as statins at reducing inflamation - ideally without the statin side effects?
Low carb will work
Stains fail to mitigate cardio-inflammation :: they cut it by such a negligible, meaningless, slight, tiny, minuscule amount for just such a short window of time that it is '''fraudulent''' to claim this. !!!!!
To reduce inflammation, I have sold curcumin, ginger, and a panoply of combination supplements in my stores convincing myself the combined synergy would have a meaningful effect for my kind, trusting customers. Now, I have self-doubts due to new fake research [[ '''disinformation'' not misinformation ]] coming from AMA, CDC, NIH, WHO..... WHO as in Who even knows truth anymore ?????
@@chuckbecker8735😂😂
@@chuckbecker8735 Your definitely right! 👍
I take 2.5 must of the time and 5 once in a while. but I, am on a vegan diet, I eat ruminant animals.
I take pravastatin and have no side effects
Your one of the lucky ones!
The title of this video doesn't seem to match the content.??
Thank you very much. I’m checking with my team to understand this better. I could understand a question format better.
@@PrevMedHealth I would actually prefer a statement of what's to come (and a more complete summary in the notes), so I know whether to watch or not. I find myself tuning in less frequently when the punchline is buried, and I can't tell in advance if it will be worth the time investment.
August 2021 Study. See Vital results to prevent Heart Events.
"Cardiovascular Benefit of Lowering Low-Density Lipoprotein Cholesterol Below 40 mg/dL"
See also that Study's accompanying reduce apoB results for reducing MACE. Heart Events. IMPRESSIVE!!!!
Try the Journal of American Medical Association - Internal Medicine "Evaluating the Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment"
2015 study title: Statins stimulate atherosclerosis and heart failure: pharmacological mechanisms. Written by Japanese scientists living in the country with the highest life expectancy.
@@StanDupp6371This is WHAT truly happens. Nov 2021 Study.
"The Effect of Statin Therapy on the Progression and Composition of Coronary Atherosclerotic Plaque Identified on Coronary CTA
Nov 12, 2021 | Brigitte Kazzi, MD; David I Feldman, MD, "
See Vital Figure 1.
I love rosuvastatin.
I am recovering from three months of rosuvastatin.
It bumped my A1c from 5.4 (which it been for years) to 5.7 in six months - and my doctor said it’s “normal” and he sees it routinely
Even if you feel fine - be careful…
Stains fail to mitigate cardio-inflammation :: they cut it by such a negligible, meaningless, slight, tiny, minuscule amount for just such a short window of time that it is '''fraudulent''' to claim this. !!!!!
What is your research compared to Dr Brewer
@@LThill-ks2uz Instead of Google, use ''Google Scholar''. Use the word ''fail'' not ''failure''. Ask your cardiologist if a statin would cut cardio inflam as well as 81 mg aspirin 3-4 times per week?
@ LTHill-ks2uz Try the Journal of American Medical Association - Internal Medicine "Evaluating the Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment"
@@deltabravo5507 Very intelligent research exhibit !!!!! The best come-back I can retort with is weak, trite, flimsy & sort of cheap..... AMA was the first of the 3 letter health organizations to be forced to confess to their proven sinister corruption. I'm not referring merely to Big Pharma but also to their capitulation to our nefarious Gov't. AMA, CDC, NIH, & WHO absolutely truly truly cannot be counted on for any truth. They are way beyond corrupt and criminal and ugly and nefarious. If you cannot see this, ask around some of the friends you have who are very intelligent like you and they will explain.
@@deltabravo5507 Thanks for the reference, which states that absolute risk reduction is 0.8% for all cause mortality, and 1.3% for a heart attack. While that sounds small, that figure represents a 1.3% reduction per year. If I'm more concerned with reducing my risk of a heart attack over the next 20 years, then I should multiply 20 times 1.3 and I'd have a 26% reduction in my chances of having a heart attack. That's why I haven't ruled statins out completely. But I prefer to try natural methods first to see if they can move my numbers for cholesterol, plaque, and BMI in the right direction.
So now Apo B isn’t related to CVD??? What a ridiculous nonsense channel
There are some more powerful anti inflammatory medications that dont have the side effects as statins do. Gluthatione is one. diclofenac NA is so far the strongest but of course it has many side effects. there are also other alternatives like tumeric or garlic tabs.
I'm taking NAC and glycine powders in order to increase my glutathione to what a young person would naturally have. It's working, because it's one of the few supplements I take where I can actually feel the difference; I feel 5 or 10 years younger.