Folate Deficiency Vs Vitamin B12 Deficiency
VloĆŸit
- Äas pĆidĂĄn 14. 11. 2017
- đđŒAnimated Mnemonics (Picmonic): www.picmonic.com/viphookup/me...
âșđšâđ«đAntibiotics Lectures: www.medicosisperfectionalis.c...
This is a series on "anemia", go to my playlist named: "hematology/oncology".
RDW is elevated in both Vitamin B12 deficiency as well as in folate deficiency.
My FAVORITE BOOK to study Pathology and pathophysiology for step 1 USMLE is Goljan, you can check it out here: goo.gl/9ojg6M
My favorite book for internal medicine is Harrison's, check it out here: amzn.to/2A7UEdj
My favorite book for surgery is this one, which contains notes and vignettes of Dr. Pestana, here: goo.gl/UdDGHq
My favorite book for Ob.GYN is Hacker and Moore: goo.gl/umFsjc
For a review book for USMLE step 1, check First Aid here: amzn.to/2zOU7w2
For a review book to study USMLE step 2CK, I recommend: amzn.to/2iI6zue
For a review book to study USMLE step 2CS, check amzn.to/2z24RtR
Check this pharmacology book, really easy to read, and inexpensive: Pharmacology made incredibly easy: goo.gl/or3DzB
If you would like a good pharmacology textbook, try Lippincott illustrated: goo.gl/PYEUP2
(Disclaimer: The medical information contained herein is intended for physician medical licensing exam review purposes only, and are not intended for diagnosis of any illness. If you think you may be suffering from any medical condition, you should consult your physician or seek immediate medical attention.)
Disclaimer: these links are affiliate links, so that I get paid a percentage of the sale, to support the channel, however, the customer is not affected as they pay the same price.
Get ready for your USMLE, NCLEX or COMLEX
Click the Subscribe button to get new videos every week.
To watch all my Hematology videos, check out this playlist: âą Hematology/ Oncology
Like my page on Facebook:
/ medicosis
Follow us on twitter: / medicosis
Follow us on instagram here: / medicosisperfectionalis
----My website will launch next year, so stay tunedâŠ
My dream is to do white board classroom teaching, audio podcast and live online webinars. But, I need your support to do this.
To help support me and keep my videos available on youtube, visit me on Patreon, / medicosis
The funniest thing is that I have a playlist containing only mnemonics, yes, MEDICAL MNEMONICS, here: âą Medical Mnemonics If you like my videos, please consider leaving a tip at www.paypal.me/perfectionalis/
âș Visit my website: www.medicosisperfectionalis.com/ My Favorite Productivity App: airtable.com/invite/r/2zH40fus/
đŒ đ„° Animated Mnemonics (Picmonic): www.picmonic.com/viphookup/me...
- With Picmonic, get your life back by studying less and remembering more. Medical and Nursing students say that Picmonic is the most comprehensive and effective way to bridge learning and test prep...
Disclaimer: I use affiliate links.... đ±Save on your mobile phone bill: fbuy.me/q6bMj đŠ Qbank (TrueLearn): truelearn.referralrock.com/l/...
đ Antibiotics Videos: www.medicosisperfectionalis.com/
Sir can you talk with me
This anemia is HIV Early symptom
???
Hey, How are you?
How can I help?
What is the reticulocyte production index? Conceptually, the reticulocyte production index (RPI) is a way to correct the reticulocyte count when anemia is present. Because reticulocyte count is a percentage, it can be distorted by the relative amount of RBCs. When RBCs are low (anemia), then the reticulocyte count will have a higher percentage, giving the false illusion that all is OK with the reticulocyte world. So, when patient is anemic, the RPI mathematical formula is used, which is RPI = reticulocyte count x (patient's low anemic Hct) divided by normal Hct (45 for a man,; 40 for a woman). You might find patient's bone marrow response is not as great as you thought!
đ©ž Hematology Playlist: czcams.com/play/PLYcLrRDaR8_eoNz6dxXolh1XMEietcniU.html&si=tomFsUjAgOKhOJVq
Love your videos. Very best one's pit there. The pictures are at the right speed & clarity that a severe brain dead tired anemic like myself can get clarity from. Keep up the great work.
Thank u sir.All the videos are excellent.I find it easy to read the topic from book after watching ur videos.
Thatâs exactly what I wanted to hear...Thanks, brother!
This is so helpful! Thank you!
My pleasure đ
Excellent video! This video is very informative and useful! Thank you for sharing.
You are always welcome!
thank you for the free medicine class
Youâre very welcome đ
B12 deficiency can be treated very well with oral OTC B12. I am a physician who had to retire at age 58 due to the psychiatric effects of undiagnosed B12 deficiency. My B12 level was 120 pg/ml. I was mildly anemic with a hemaglobin of 12.6. I diagnosed myself and started taking 5,000 mcg of OTC methylated B12 four times per day. I am now just taking one tablet every four days, and I am doing quite well on that. Studies have shown that the oral B12 is more efficacious in the long-term in treating B12 deficiency. I have autoimmune B12 deficiency which is Pernicious Anemia. I did take iron as well, and the anemia cleared up rather quickly. I have a great aunt who had Pernicious Anemia and died in a swimming pool from a sudden rupture of her abdominal aorta. She had stopped going to the doctor for her B12 shots for some unknown period of time before her sudden death. It is well known that B12 deficiency has a degenerative effect on blood vessels.
Can it cause hairloss? I have B12 level 409 pg/ml, while folic acid level is
Very well but the B12 oils or the lozenges are much much better and more effective
Literally this makes no sense. Oral B12 will NOT work for pernicious anemia! PA literally means you do not have intrinsic factor and therefore can NOT absorb B12 via digestion. You MUST recieve intramuscular injections so they bypass gastro and go directly into bloodstream.
I call bull$hit.
Pernicious Anemia needs b12 injections. It will not resolve with tablets
â@@jbeauty4150 of you have PA you need injections for life.
I hope you can help me with my question. I had an undiagnosed vitamine B12 deficiency and now get IM injections. I'm looking at my bloodwork to make arguments for vitamin B12 deficiency because doctors here are terrible with diagnosing. Im doing much better after injections and my bloodwork has stabilised. My reticulocytes were 15 o/oo and now 18 o/oo (normal occurence with start treatment). This value is different from others on the internet in percentages. Do you know what my reticulocytes are in percentages from that value?
I had so many "gaps" in my knowledge while studying... Now everythig makes sense. Thank you so much!
Please, please do a video on homocysteine/homocystinuria/homocysteinemia.
Thank you so much đ, Diana!
Your kind words mean the world to me!
I will add this topic to my list!
@@MedicosisPerfectionalis have you already done it?
Retic count *pts hematocrit/ normal hematocrit.
If less than 2.5 than usually nutritional deficiency anemias.
Thank you so much Dr!
Do you have a video on red blood cells expiring before they are maturing?
What is RBC count . Does it increase or decrease in Macrocytic anemia
I have cases with microcytic anemia . Thalassemia trait as well as Iron deficiency.
In India we also have Dimorphic anemia. How to diagnose
You are just outstanding .
Superb teacher
I have high MCH, MCV, Hemoglobin and Hematocrit. My Reticulocyte count is 1.8 but my Absolute Reticulocyte count is high @ 90180. Iâm waiting for my Homocysteine levels. Iâm leaning towards Folate deficiency. Does anyone have any thoughts or ideas?
My blood test show I was low in folic acid. I ordered folate because suspect I may have methylation problem. I took bone yesterday and all my inflammation and nerve pain increase. I had horrible rise in histamine. When I googled it said that folate can raise histamine. Please can someone tell me how can I raise my folate without this reaction?
What does a low MMA count mean?
Thank you.
What about vitamin b deficiencies for people genetic issues, such as mthfr c677t? In my area the are either a lot of doctors that donât know what vitamins I should take or what I have seen online is wrong. I know there are so many factors to consider, but what type of doctor can give me the correct information?
A pediatric hematologist or a hematologist.
I hope you see this.. So b12 deficiency runs in the family on my dad's side. I didn't really have that in my dna test. I have mtrr a66g which is I think the ability to reuse b12. Anyways I've had fatigue on off my whole life. Tingling in hands and feet. Red ear syndrome which I don't think is related etc. However my blood test always come back normal. Is it still possible to be deficient with normal serum b12 ?
RPI = CORRECTED RC/2 or (Patient's HCT or Hb/Expected HCT or Hb for age and sex) x RC/2
Thanks man for info
Youâre always welcome đ
I am so thnkuful u sir, I can't explained how much I am happy ,u provided free medicine leacrure this is the only week point me,thnku So much from india
Tremendous video, doc.
Thank you so much đ
@@MedicosisPerfectionalis You're very welcome. đ
It's frustrating looking for answers in the comments. Please try to give the answers in the description and we won't have to change apps and won't get distracted đ .
Thank you so much for your feedback
My MCV is 88 but my MCHC is 36 and hemoglobin is 17.5
Question my 17 yr old daughter has a slightly low wbc @ 4.
Low platelet @ 133
High MPV @ 13.9
She was having heavy periods
And stomach issues like ibd
The doctor is doing another cbc & blood smear
I'm just worried
No I'm not a student but my mom was a N.P
and I picked up alot of medical knowledge from her. But pernicious anemia and autoimmune disease runs in the family
But of course The Big C word scares me more than anything
Suggestions on what you might think it is?
Wait for the results of the CBC and smear.
Thank you!!
Youâre always welcome!
Can you tell what happens to the homocysteine levels when vit B12 is more than normal but folate is decreased?
It may increase
RPI = Hct of patient /normal Hct * retic count
Please make some biochemistry metabolism videos..you are the best
I will!
Thank you đ
Thanks a lot ..l prefer your videos so much
My pleasure đ
I am deficient in b12 but have good hg level and RBC . Should I take methylecobalamine injections?
Talk to your doctor!
if you want a simple explanation
you were attacked by microscopic
aliens and you need the avengers
I had b12 serum coming back fine yet i have had high homocysteine high, does that mean i don t have sufficient b12 even though test came fine? I feel so bad since 5 years... no one knows why
Functional deficiency
Get your coagulation profile.
Reticulo means net work and cyte means cells (baby RBCs) and it must be between 1-2%
What does it mean when my b12 is high but my folate is low?
I donât know your history, physical exam, or other labsâŠPlease talk to your doctorâŠI wish you all the best!
Thank you so very much.
My pleasure! Thanks for watching!
I have high RDW , low mch and low mcv
What does this mean ?
My hemoglobin is also slightly low
May be iron deficiency anemia.
But, I am not a doctor and I cannot diagnose you on the internet.
Please talk to your doctor!
I wish you the best!
Medicosis Perfectionalis thanks for the quick reply ! Iâll go in next week for vitamin testing/bloodwork
Excellent! Keep me updated!
@@MedicosisPerfectionalis i hope she got well
I have neurological problems but my overall b12 count has come back fine is it possible that i still have a b12 deficiency?
Can be loads of things, try liquid chlorophyll wish has copper in it wish also has the same symtoms as B12 deficency, also take a b complex, vitamin d with k2, eat healthy, probiotics, you name it, just do your research, you also need to take folate with B12, not folic acid, so methyl b12 and folate
Yes you can and trying to get a Doctor to listen is hard, every NHS trust has different levels of what is acceptable so if your GP tells you itâs fine you could move to a different county and you could get supplemented, I have been through all this with different Doctors, even on the NICE website which the NHS have to follow, it states that if a patients levels are fine but still presents with low B12 symptoms then supplementation is recommended, my advice is get as much evidence as possible and present it to your Dr, and thereâs a lot of helpful info on this linkwww.b12deficiency.info/ I also found out that if you take any sort of acid relief medication it prevents your body from absorbing B12 as this is what happened to me after having gallbladder surgery, I hope this helps a little
@@1273mel thanx Mel đđ»
Lfc Scouser thatâs ok cus I know how annoying it is, because Drs donât listen so Iâve done my own research over the last couple of years and learnt so much about health and how deficiencies/gut health etc can impact on the body, Drs either put everything down to anxiety or dish out pills just to get you out of the door...also if you did want to supplement with B12 you canât overdose on it as anything the body doesnât need you pee out, I purchased a daily oral spray and I wouldnât be without it
How long does it take for the folic acid tablets to start working
The Godfather i took some and was told several months... but itâs definitely worth it
How many months does it take for the b12 supplement to work?
It starts working right away. How fast you improve is directly related to the dose you are taking.
Which is the best to buy on Amazon? My hair is falling out
My folate is 9.8 is this normal
Awesome , but I have a question if b12 deficiency can I give folate as well with b12 or should I wait for folate lab value to confirm it's deficiency ?
It doesnât do any harm, plus the folate level test doesnât take long (itâs not like bacteria culture)
Thank you so much, I'm grateful to you.
My pleasure đ
The administration of folic acid to a patient with vitamin B12 deficiency may worsen neurological symptoms.
Check out these two articles :
www.ncbi.nlm.nih.gov/pubmed/7796091
www.ncbi.nlm.nih.gov/pubmed/17972439
@@fatimazahrarahali458 yeah I think you are true in case he have both deficient (Vit b12 and Vit b9); and he takes Vit b9 ALONE.. This is going to lead to severe neurological sxs becz the Vit b9 supplements are going to react with the remaining Vit b12 in his body ;and no remaining Vit b12 for melanoyl coA pathway so severe neurological sxs are going to appear. BUT, here the patient asked if he can take both together Vit b9 and Vit b12..
I take b12. Should I also take folate; or is it unnecessary to take them both?
Before you start taking folic acid, your GP will check your vitamin B12 levels to make sure they're normal. This is because folic acid treatment can sometimes improve your symptoms so much that it masks an underlying vitamin B12 deficiency.
Thanks, but I have problem with stomach, I have bloated stomach, dry skin, dry scalp along with extensive dandruff and much more..which vitamin B could be. When up my diary consumption o feel better. But I am tired of diary, any suggestion?
I donât know đ€·ââïž
Please talk to your doctor!
Lmao, maybe leaky gut, ibs, candida, sibo, probably deficency in all vitamins, its hard to tell by your symtoms, and for the love of God don't consume dairy, no wounder why you are bloated
Also just take a b complex you should never take a b vitamin by itself if its not b1, liquid chlorophyll now foods brand great for dry skin
But there are more than that, you need to change your diet, extremely healthy, alot of veggies, maybe keto diet and vegan also, get some probiotics also
You donât know the diagnosis, how can you recommend treatment?
what is the CONFIRMATORY test for megaloblastic anemia ?
Bone marrow?
+Alamin Almughrabi Yes, bone marrow biopsy is the confirmatory test showing macro-ovalocytes and hypersegmented neutrophils. It may be important to confirm or rule out myelodysplastic syndrome (MDS), because it gives high MCV as well.
Medicosis Perfectionalis Thanks Doctor for your help đ€đ€đ€
+Alamin Almughrabi Donât mention it...I am still a student by the way :)
...Good luck
@@MedicosisPerfectionalis you will for sure make the best doctor i the present century
My MCV is 70 only...what does that mean
Whatâs the Hemoglobin and hematocrit?
Excellent excellent excellent đđđ
Thanks đ
This is early HIV symptoms?
Great Jobđđ
Thank you...Thank you...Thank you đ
Thank you for the explanation
My hemoglobin is 153 ( High)
Mcv is 82.5 (low)
Iron serum is 25.8 (high) this is my functional medicine ranges but i am confused what type of anemia do i have? Is it pernicious?
Your hemoglobin is 153?!!!!!
Medicosis Perfectionalis yes
Hemoglobin (SI) 153 -
normal to optimal range is 135-150 g/L
According to functional medicine test ranges.
My folate was also high 40.68 and the normal to optimal is 14-36 nmol/L
Confused!
Medicosis Perfectionalis i had some gut issues and hypochlorhydria , h pylori and candida due to long term use of anti Acids i did treat these but need to know what type of anemia is this.
thankss a lot
My pleasure đ
B12= 1297 on my husbandâs last test
Heâs feeling fine but Iâm worried
Any suggestions?
Facing same problem how r u now
@@sumeenahmed5099
Donât know yet
Dr stopped multivitamins but I donât think itâs a problem
Iâve read that it can actually be a sign of LOW b12 bc itâs not absorbing
@@user-tx5rx3mz8b
So far so good đđđ»
Immaculate, thanks doc
My pleasure đ
So i need mora stomach acid to have a good gut?? And how i do that
Thereâs no way to increase it.
You already have enough (unless you have achlorhydria)
Diego Ezeith apple cider vinegar will do it
@@MedicosisPerfectionalis what are you talking about? There are loads of things to increase stomach acid, Hcl betaine or acv are the main ones
Betaine hcl or apple cider vinegar braggs
What hard evidence do you have?
ty
My pleasure đ
18 years old student came to his physician with the following symptoms Abnormal paleness or lack of color of the skin, Yellowish skin, eyes, and mouth (jaundice), Dark-colored urine, Fever, Weakness, Dizziness, Confusion. His lab finding is as follows: Hb Decreased Reticulocytes Increased 5 to 20% MCV Normal MCHC Increased Bone marrow Erythroid hyperplasia Coombs test Direct is positive RDW Increased Serum bilirubin Raised RBC Morphology Normochromic and normocytic What is your diagnosis?
Is this a real patient or an exam question?
It was in my exam ?
Mds?
you forget an important thing in different between B12 and Fol.
which is storage.mo.for folate and years for B12....thanx
Mentioned it in my Vitamins playlist.
2020/9/2
2.5
Eye opening
đ
I request u to reply me first of all
Plz tell me that can i use folace and myfol together??
9-21
Children.8-1.8
Adult .5-1.5
I have B12 and folate ifound out a week ago but my doctors have failed to inform me or offer me đ none diet related x
A 12 years old girls was seen by her physician. Her chief complaints were shortness of breath, muscle weakness, abnormal paleness of the skin, glossitis (swollen tongue), loss of appetite/weight loss, diarrhea, nausea, fast heartbeat. The relevant lab results were as follows: Peripheral Blood Picture: MCV 110 fl (77 to 93 fl) MCH 34 pg (27 to 32 pg) MCHC 24 g/dl (20 to 25 g/dl) Hb low RBC count reduced DLC Marked neutropenia, hyper segmented neutrophils RBC shows Macrocytosis, anisocytosis, poikilocytosis, polychromasia. What is your diagnosis?
Is this a real patient or an exam question?
It was in my exam ?
â€â€â€