Why mRNA Vaccines Were Insanely Difficult to Make (it took 50 years!)

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  • čas přidán 6. 06. 2024
  • Why are vaccines so hard to make? The FDA approved two mRNA vaccines for COVID-19, but it was a challenge to make this type of vaccine work. In fact, it took decades of research to get us to the point where scientists could make those vaccines as quickly as they did! Learn all about it with Hank in this new episode of SciShow!
    Hosted by: Hank Green
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    Sources:
    www.frontiersin.org/articles/...
    www.ncbi.nlm.nih.gov/pmc/arti...
    www.nature.com/articles/s4154...
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    Images:
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Komentáře • 7K

  • @lorny200
    @lorny200 Před 3 lety +2528

    Was watching scishow when I was still a young 12 year old student, and now a graduate in biochemistry. Thank you for instilling passion in science to all.

  • @danielm5535
    @danielm5535 Před 2 lety +107

    I know this comment is late to this video, but at the time of this video, someone I know was diagnosed with a Stage 3 hard-to-treat cancer, and she was able to be a part of one of these mRNA trials which put her cancer into remission.
    Hope the research continues- it has amazing potential! ☺️

    • @Hyumanity
      @Hyumanity Před rokem +3

      Did she get her COVID shots?

    • @ex8280
      @ex8280 Před rokem

      @@Hyumanity she dead.

    • @SooSmokie
      @SooSmokie Před rokem

      Sure, it has its uses, just not in immunology. as we see with studies proving traditional vaccines more succesful.
      So with things like cancer and aids it's awesome.

    • @sunnesonne
      @sunnesonne Před rokem +3

      Now hankie got the cancer, most likely because of the shot too lol

    • @SacredDirt
      @SacredDirt Před 8 měsíci

      yah. he is kinda dumb and "processed". he's like the processed food of "science" @@sunnesonne

  • @danparish1344
    @danparish1344 Před rokem +9

    Doesn’t matter if the tech is 1000 years old. There’s a reason why vaccines go through long trials - every one is unique and has unknown risks. Many vaccines never reach the market.

  • @Sunset309
    @Sunset309 Před 2 lety +6

    50 years to make and another 74 years to release the clinical trials

  • @pixicraft7126
    @pixicraft7126 Před 3 lety +2654

    me seeing the title: wait it's been 50 years? no wonder quarantine felt this long

    • @HShango
      @HShango Před 3 lety +57

      I'm 27 and I feel like I'm 50 years old, which absolutely weird

    • @Kevin-sy8uf
      @Kevin-sy8uf Před 3 lety +60

      @@HShango this past year has been quite a decade

    • @fvckyoutubescensorshipandt2718
      @fvckyoutubescensorshipandt2718 Před 3 lety +11

      Get some hobbies you enjoy and a monthly welfare check then time doesn't mean much of anything. I haven't left my apt since 2006, only thing Covid did is make things out of stock and take longer to get. I don't mind waiting an extra 6-12 months, patience is a side effect of time having not much meaning. I usually get my stuff direct from China anyway, and that took 1-3 months from the time you order even before Covid.

    • @fvckyoutubescensorshipandt2718
      @fvckyoutubescensorshipandt2718 Před 3 lety +3

      @@Kevin-sy8uf yeah and that's still true for the most part. I was referring to the 6-12 month wait after ordering anything with silicon chips in it. Even Ford had to shut down car production after they ran out of chips (stupid to make cars computerized anyway, they worked just fine in the 1980's when it was just a mechanical carburetor). Started saving 3 years ago for a new PC build, looks like it'll be another year before I actually have the parts in hand.

    • @jhoughjr1
      @jhoughjr1 Před 3 lety +6

      2 weeks to flatten the curve

  • @gregsettle9725
    @gregsettle9725 Před 3 lety +1079

    I'm hoping this technology works in treating cancer. I'm a two-time cancer survivor and would love to see surgery, chemo, and radiotherapy become a thing of the past.

    • @petenielsen6683
      @petenielsen6683 Před 2 lety +18

      It will be 20 years for me this September.

    • @Trajikbpm
      @Trajikbpm Před 2 lety +86

      They willl never let that happen. Cancer is too profitable

    • @tamarafletcher7965
      @tamarafletcher7965 Před 2 lety +34

      Big pharma wouldn’t allow that. That’s how they make their money. The sicker the richer. Look into Dr.Sebi and alakaline diets. Alkaline bodies can’t get cancer.

    • @gregsettle9725
      @gregsettle9725 Před 2 lety +35

      @@tamarafletcher7965 Big Pharma will be selling the treatment, whatever it is.

    • @jmelande4937
      @jmelande4937 Před 2 lety +130

      @@tamarafletcher7965 that's rediculous for several reasons:
      1. Unless you have a critical illness, everyone's body is always alkaline at a pH between 7.35 and 7.45. Multiple organs (especially the kidneys) maintain that pH no matter what you ingest.
      2. Cancer development is a complex process, but we've developed a fairly good understanding of how it happens. The topic is too complex for a CZcams comment and there are several known variations of how it occurs, but it starts with your inherited predilections, is further induced by random mutations that cause abnormal cell reproduction, and then becomes cancer when those rapidly reproducing cells aquire traits that maintain growth and spread. But mutations start it all.
      3. pH is NOT one of the factors that results in DNA damage and mutations.

  • @GiselleBel
    @GiselleBel Před 2 lety +10

    That was fascinating! Thank you so much. I will need to watch this another couple of times to pick up all the bits I missed - that was a massive amount of information. Thank you very much for it.

  • @ZZ-sb8os
    @ZZ-sb8os Před 2 lety +1

    Thank you SciShow! SciShow was probably my 2nd or 3rd channel I ever favorited, back in the early days of YT, and since then I've recommended it to literally hundreds of people. You're almost at 1.5 billion views, keep up the awesome work!

  • @lightbox617
    @lightbox617 Před 2 lety +143

    I was taught about MRNA in high school in the mid 1960's. It took 50 or so years to figuer out how to use it. That ability has been around for nearly a decade. Every time someone tells me that the tech is too new to be trusted, I tell them this story. Not that it matters. As a race, we seem unable to to accept new ideas or ideas that are new to us.

    • @annejeppesen160
      @annejeppesen160 Před 2 lety +4

      mRNA (messenger RNA) is an essential part of organisms, just as important as DNA. The new thing is to basically genetically modify single cells to produce proteins similar to the ones from the virus and then make the immune system "learn" to recognise the virus.

    • @annejeppesen160
      @annejeppesen160 Před 2 lety +18

      @I invented Google neither is antidepressants, cholesterol reducers or blood pressure reducers

    • @playnicely9726
      @playnicely9726 Před 2 lety +13

      @@annejeppesen160 Exactly! Neither is any pharmaceutical drug. You just drove the point home with your comment! These things prolong sickness. They don't cure it or make it go away. But once the body becomes dependant on these things, you then lose the natural ability to heal yourself. Your immune system will not work if it is tricked into believing that it doesn't need to.

    • @andi56837ykvk
      @andi56837ykvk Před 2 lety +1

      Yeah it definitely seems like that! You can’t simply introduce new concepts upfront because they get rejected. Instead you’ve got to introduce it gradually over time. In this case, unless you’re reading up about mRNA along the discovery journey, it seems sudden and gets rejected - which we’ve seen world wide. The facts have been out there along the way, but they’re not usually something the majority will pay attention to. So when we received several different vaccines, it freaked people out. Personally I took both shots of the covid vaccine upfront, but it is good to know that 1. the foundation was already there, lowering the time required for creation, testing and production of the virus. 2. Going forward making vaccines will be that much easier to make. There are so many things we need vaccines for. It’s very promising news!

    • @codyosborne8926
      @codyosborne8926 Před 2 lety +18

      @@andi56837ykvk I have been following mRNA tech since 2012. So about a third of my life. I still reject it. Live attenuated vaccines have been around much longer, yet every new application is thoroughly tested. Just because the foundation of the technology, used for a wide range of experiments, has been around for a while, doesn't mean it shouldn't still be tested. It has never been used this way in humans. Ever.

  • @CarlosBeo
    @CarlosBeo Před 3 lety +1628

    Or as my weird uncle would say: Look they've been planning this for decades...

    • @futuristiccat5636
      @futuristiccat5636 Před 3 lety +52

      Oh yeah. Same with literally everything in this world

    • @kennethiofi3839
      @kennethiofi3839 Před 3 lety +48

      Eh that's why history is important. Look at cancer vaccines for example, the science makes sense currently, but it reality, they work very poorly for now.

    • @jhoughjr1
      @jhoughjr1 Před 3 lety +56

      so when did we go from every immunologist saying “we will never have a cure for the common cold”

    • @jhoughjr1
      @jhoughjr1 Před 3 lety +100

      this is asking for autoimmune disorders.

    • @doppler3237
      @doppler3237 Před 3 lety +15

      @@jhoughjr1 explain.

  • @davidcramer4282
    @davidcramer4282 Před 2 lety +7

    Hi Hank. I have become an aficionado of all your shows, including chemistry, biology etc. I am a retired engineer and this methodology for producing the vaccines is micro-engineering with gloopy stuff. I have enormous respect for the amazing hard work and sometimes genius that goes into medicinal chemistry. In fact, it saved my life when I was particularly sick at one time. Many thanks to your channels for producing all the easy to understand, yet technically deep stuff.

  • @TaterTotsNFanta
    @TaterTotsNFanta Před 2 lety +1

    Thank you SciShow!! You guys are the best!!

  • @kurtkennedy333
    @kurtkennedy333 Před 3 lety +1008

    Wow. This answered literally every question I had about how RNA vaccines are different than previous ones. As always, thanks!

    • @TheaSvendsen
      @TheaSvendsen Před 3 lety +26

      Me too! But most importantly, how it was at all possible to develop a vaccine in only a year, and especially since the previous record was four years!

    • @donniethomas7013
      @donniethomas7013 Před 3 lety +42

      @@TheaSvendsenIt's all BS which is why HIV and MERS which are still present today have NO vaccines.

    • @meddy357
      @meddy357 Před 3 lety +9

      @@TheaSvendsen absolutely incredible. Too bad it's not so easy to create a vaccine for all viral infections because so many factors make a huge impact such as money poured in, or lack thereof, how quickly the virus mutates and just the quantity of varients of the same virus there may be, like HIV.

    • @simonroy2123
      @simonroy2123 Před 3 lety +53

      @@donniethomas7013 MERS never had a vaccine because there's basically no cases. It's impossible to conduct a clinical trial when the virus is barely active.

    • @juanaguilar37
      @juanaguilar37 Před 3 lety +33

      @@donniethomas7013 The same technology used in the covid vaccine has been used to cure HIV patients successfully and it is currently being tested in clinical trails.

  • @CyberiusT
    @CyberiusT Před 3 lety +509

    "proteins are all foldey and weird"
    Man, that's burned into the memory, right beside "wibbley wobbley timey-wimey stuff".

    • @virium4031
      @virium4031 Před 3 lety +14

      And thus a Whovian is detected :D

    • @CyberiusT
      @CyberiusT Před 3 lety +4

      @@virium4031 :) Only lightly, though. Never really got far past Tom Baker, though I did like Ecclestone's take on the role.

    • @kellydalstok8900
      @kellydalstok8900 Před 3 lety +6

      But surely that weeping angels episode was great.

    • @CyberiusT
      @CyberiusT Před 3 lety

      @@kellydalstok8900 Only caught part of that one, but it looked good.

    • @Tropicalpisces
      @Tropicalpisces Před 3 lety +1

      @@CyberiusT his is delightful. Far too brief.

  • @whiskyguzzler982
    @whiskyguzzler982 Před 2 lety +1

    Great explanation! Always good to hear from Hank!

  • @gregorymunby2065
    @gregorymunby2065 Před 2 lety +1

    Such great content!! Thanks SciShow crew.

  • @MagicianFairy
    @MagicianFairy Před 3 lety +562

    The wanted poster.
    My inner 12 year old- *chuckles*

    • @FrozEnbyWolf150
      @FrozEnbyWolf150 Před 3 lety +21

      Yeah, those are clearly flower pestles, which plants use to reproduce. Stop thinking about plant sex, SciShow!

    • @GraemeGunn
      @GraemeGunn Před 3 lety +13

      I hope that's not what you think human male genitalia looks like.

    • @celestenamya5537
      @celestenamya5537 Před 3 lety +17

      I busted up laughing when they zoomed in on the poster, surprised no one caught that during the editing process

    • @crunchie83
      @crunchie83 Před 3 lety +3

      @@theyredistortingyourrhythm. (sigh)

    • @billylerch1776
      @billylerch1776 Před 3 lety +1

      @@theyredistortingyourrhythm. thanks for the true message....people are wide awake...and the number is massive...and they can't stop it...

  • @TenaciousBOD
    @TenaciousBOD Před 3 lety +86

    Helped me smash out a 3rd year biochem assignment in 3 hrs ezpz thanks man, also the references helped lots, would love if you flashed the reference as you were referring to something too that'd be epic

  • @davidpaulcarlson8763
    @davidpaulcarlson8763 Před 2 lety +3

    You do such a good job of explaining complicated things. Thank you.

  • @l.mcmanus3983
    @l.mcmanus3983 Před 2 lety +12

    Getting genetic material into plant cells can be even more difficult because of cell walls. A lab I worked at during my undergrad used gold nano particles coated in DNA shot into the cell to get the job done. And it still did not always work.

  • @JOHNCHENSJCA
    @JOHNCHENSJCA Před 2 lety +149

    Thank you, SciShow, for making a timely topic succinct and easier to understand-with brevity! Thank you, Hank, for the usual attention retaining delivery! SciShow is a nice dive below the surface of the headlines. As a boomer, I’m happy to find a substitute for PBS Nova.

    • @jsallu7239
      @jsallu7239 Před 2 lety

      Listen to Dr Robert Malone, the inventor or MRNA, he is against these current vaccine mandates. czcams.com/video/nYkUePQMfkE/video.html. Recently did an interview with Joe Rogan.

    • @aaroncarr-mackay2457
      @aaroncarr-mackay2457 Před 2 lety

      Menstrual cycle not mental

  • @FortisKnight
    @FortisKnight Před 3 lety +20

    Quite a positive change in clarity. My gratitude SciShow, yet again!

  • @gaetanotrina9194
    @gaetanotrina9194 Před 2 lety +1

    Wow!You are so clever in explaining all this topic...many thanks.

  • @kevinscanlon376
    @kevinscanlon376 Před 2 lety +48

    Well done, I am one of those scientists that has worked on mRNA since the 70’s. Delivery and selectivity of RNA therapeutics were the key challenges in the medical field. I was Co-Founder and Co-Editor of Cancer Gene Therapy.

    • @Jsmash88808
      @Jsmash88808 Před 2 lety

      Ribozymes in Gene Therapy of Cancer. To be honest I don't even know what that means. I'm trying to self educate for my friends and family. Could you give a little insight as to what exactly your book covers? Is the content something the average person would be able to digest and understand? Thanks in advance.

    • @priscillabenner2085
      @priscillabenner2085 Před 2 lety +2

      I am a physician trying to share information with my patients regarding the mRNA vaccines. I have sent the link to this video to many who are vaccine hesitant. Thanks for providing this service. I suspect that your good work has saved lives. I would encourage everyone to send the link to all their friends and loved ones and even to people that you don't like, come to think of it! 😷

    • @priscillabenner2085
      @priscillabenner2085 Před 2 lety +1

      Thank you for your work!

    • @ninavanina8455
      @ninavanina8455 Před 2 lety +2

      I had my 1 dose of moderna . Mg face got paralyzed. Arm pain, body ache . Second day went away . But 3 day came back the feeling of needle abs tingling in my face and dizziness!
      Is is not la this side effects ? Will it go away ?

    • @badgerpa9
      @badgerpa9 Před 2 lety +4

      How come the vaccine does not work if I am around someone unvaccinated? I thought a vaccine was for the person getting the vaccine, now I am told if someone was not vaccinated my vaccine will not work, why should I have had the shots then? Does not make sense that I will never see someone unvaccinated later in life. Also why have people vaccinated when I was still passed away from covid but they did not go by anyone unvaccinated, 2 people I know have died, about 4 weeks after being vaccinated, was the vaccine no good?

  • @AwesomeBoysJPTV
    @AwesomeBoysJPTV Před 3 lety +279

    People should watch this video and know that the reason that the vaccines were made that quick is not because of conspiracy theories, but it is because of 50 years of hardwork and dedication of scientists to make this mRNA vaccine and idea come to life!
    Great Video

    • @MargaretBelle
      @MargaretBelle Před 3 lety +23

      my thoughts exactly. whilst scepticism is healthy they failed to interrogate why and how this was possible

    • @AwesomeBoysJPTV
      @AwesomeBoysJPTV Před 3 lety +4

      @@MargaretBelle How it was possible? Years or Hardwork and research. They didn't explain all of it in this video because maybe we will leave the video out of boredom

    • @MargaretBelle
      @MargaretBelle Před 3 lety +9

      @@AwesomeBoysJPTV oh no I didn't mean the video I meant conspiracy theorists. sorry that wasn't clear!

    • @AwesomeBoysJPTV
      @AwesomeBoysJPTV Před 3 lety +9

      @@MargaretBelle no worries. Even I, a high school science teacher have some skepticism on the new vaccines, but as I learn the history and the process(summarized) of it all, it becomes clear now.

    • @AwesomeBoysJPTV
      @AwesomeBoysJPTV Před 3 lety +6

      @@MargaretBelle Yeah, conspiracy theorists Sometimes make irrational reasonings to their stories

  • @bobmcl2406
    @bobmcl2406 Před 3 lety +594

    They say that the definition of luck is when preparation meets opportunity. By that definition, we certainly were "lucky". Kudos to generations of scientists! And this video is magnificently written.

    • @--___--d
      @--___--d Před 3 lety +2

      Yes, such good point :D
      I wish we could have a blooper/react video when he got to read the script they prepared for him the first time, to see his reaction to the text he read ^^ would be cool

    • @Dark_Angel555
      @Dark_Angel555 Před 3 lety +30

      You actually believe that we were lucky and covid came at the right time - I don't... it was planned - don't believe in global scale coincidences - only small ones

    • @gromm93
      @gromm93 Před 3 lety +18

      If anything, the real luck in this case was the *lack* of opportunity. With the exception of the HIV pandemic, there haven't been any major pandemics (especially from airborne diseases that are very easy to catch from casual contact) in the past 100 years.
      That meant that research could be done in peaceful times when the need wasn't quite so urgent. We could calmly make mistakes in small studies and figure out solutions to those problems, letting science plod along as it does. Imagine what would have happened if Covid happened 10 or 20 years before mRNA vaccines were ready, and they were rushed into service with major side effects. The public trust in such technology would have been utterly obliterated overnight. The history of science is full of incidents like that, with scientists apologising for the errors and promising that the new thing will do a better job, only for the public to violently oppose them.
      Instead, we're lucky that this biotechnology was fully mature at a time when it was needed the most. If anything, it would have been nice to test out this technology on some other vaccine rollout 5 years ago, demonstrate that it's awesome, and then have it jump to the rescue right now.

    • @ssjDayzeD
      @ssjDayzeD Před 2 lety +18

      Yes we're extremely lucky that fauci and Bill gates put all their investments into vaccines while funding gain of function in China.
      If that's not luck I don't know what is!

    • @Some111
      @Some111 Před 2 lety

      Generations of scientists? Do you mean Dr. Robert Malone the self proclamed inventor? 😂

  • @jefnam2576
    @jefnam2576 Před 2 lety +44

    I know it's standard for professional pieces, but I REALLY appreciate the sources in the description. And the video too. A wealth of information all in one spot, thanks SciShow!

  • @pthaloblue100
    @pthaloblue100 Před 2 lety +2

    Thank you so much, I was hoping for a Sci-Show video on this topic! I've done plenty of reading, but I was looking for a clear, short explanation to refer back to on how mRNA vaccines work.

  • @LovecraftBur
    @LovecraftBur Před 3 lety +93

    2021 is paid version of 2020

    • @LuinTathren
      @LuinTathren Před 3 lety +15

      Yeah, but then there's the DLC and in-app purchases to get 2022.

    • @smoogle3g4c37
      @smoogle3g4c37 Před 3 lety +11

      Do I smell a battle pass?

    • @LovecraftBur
      @LovecraftBur Před 3 lety +1

      @@smoogle3g4c37 guess you still in the Game if you can still smell G... 😎😎

    • @BruhMoment-fh8zc
      @BruhMoment-fh8zc Před 3 lety

      Lmao

    • @jarencascino7604
      @jarencascino7604 Před 3 lety

      @@smoogle3g4c37 i mean literally every game has one at this point

  • @gwenp3450
    @gwenp3450 Před 3 lety +11

    Thank you for providing this detailed, yet easy to follow explanation.

  • @westwoodoralsurgerydentalgroup

    Amazing video… so thorough!

  • @sarahgardner8856
    @sarahgardner8856 Před 2 lety

    This is amazing, thank you for the video

  • @mjmulenga3
    @mjmulenga3 Před 3 lety +157

    "Great science never happens in a vacuum."
    International Space Station: "Am I a joke to you?"

    • @russell1841
      @russell1841 Před 3 lety +1

      lmao this is a good one

    • @laurieb3703
      @laurieb3703 Před 3 lety

      Hehehe

    • @sreedharreddypochana2892
      @sreedharreddypochana2892 Před 3 lety

      Hi Namaste🙏 to all world including Nature 🌲🌳🌴 & Sunlight.
      Corona or any disease million dollars business.
      it creates more customers spoiled all life & But Making money.
      What's Best Vaccine means:
      1) Lovely Enjoying with Nature 🌿🍃🌿🍃& Sunlight 🌕🌕🌕🌕.
      Ginger-Garlic- Pepper paste is a greatest antiviral property.
      Next All of us Don't use Sanitizer🧴🤲 ( Sanitizer get causes Cancer) &wearing of face mask 😷( Insufficient breathing problems to all).
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      All of us Daily morning will start mouth wash wish Neem stick or Charcoal powder mix with little bit salt & 1 or 2 cloves & 1or 2 peppers.
      Next go to Drinking activity- All of us will prepare Ragi malt mix with Sonti 🍵 :& Drink it.
      One more All of us will take 5 teaspoons Gingelly seeds& 2 teaspoon s mustard seed heat with low flame for 5 min & little bit add Vamu& Vaza & prepare powder store in glass bottle & All of us Daily morning little bit will take through hot water.
      Definitely all our body organs 💃🕺👯 movement happening .
      Next go eating activities All of us will prepare millet food & eat it.
      All of us Daily will eat thulasi leaves-5 & curry leaves-5& Moringa leaves-5, Neem leaves-5.
      All of us Don't afraid of Corona or any health issue.
      All of us one think will save all our Brains.
      What's one think means Covid or any heath issue is a not virus or any health issue- Covid or any health issue is our best friend( No body can seen any virus in any area).
      Next go to FDA Guide line's.
      What's FDA full meaning ( Food and Drug Administration).
      FDA- F means Food &who are making Food means - Family Former.(F=F this is making happy life 💯👌OK) &
      initially all of us Food making with out Pesticides.
      That time All is always well with lovely enjoying with Nature & Sunlight.
      Along 40 years all of using Pesticides making food with Pesticides Spoiled land life & Human life.
      What's one think means Covid is a not virus( No body can seen any virus in any area) & Don't afraid of corona from all our side.
      FDA-D means- Disease=Doctor=Money or Dabbu( Dabbu( Money) , Gabbu ( Dirty) , Jabbu( Disease).
      Finally this D Making money & Bad life.
      FDA- A Means Administration.
      Finally which letter is better or administration to all world out of 3 Capital letters means - F is ok 👌👌👌👌👌👌👌👌👌👌👌👌👌👌👌👌👌👌👌👌👌👌👌👌👌....... .

    • @orangetabby3229
      @orangetabby3229 Před 2 lety

      Good one! I like that 👌Lol

    • @TheRadiastral
      @TheRadiastral Před 2 lety +2

      The only problem is, inside of the ISS is not a vacuum, it's filled with air. But that doesn't apply to experiments done *outside* the ISS, of course. Just saying ;)

  • @yazminmojica4458
    @yazminmojica4458 Před 2 lety +206

    👏🏼👏🏼👏🏼👏🏼👏🏼 a school semester in 12.5 minutes, excellently well done 👍🏼✌🏼💕

    • @timbookedtwo2375
      @timbookedtwo2375 Před 2 lety +1

      It was crap.

    • @winston100win
      @winston100win Před 2 lety +1

      @@timbookedtwo2375 😂

    • @islandercirce2
      @islandercirce2 Před 2 lety +4

      It's not bad. The information was good but went a bit too fast. That speed might be fine if a person is at all familiar with the information but the presentation often rushed from one thought to another without any time to process so I personally found it difficult to keep up. I guess that I'm generally better with written presentations for complex matters.

    • @yazminmojica4458
      @yazminmojica4458 Před 2 lety +6

      @@islandercirce2 Hi, you can always change the speed of the video if it’s to fast or too slow for you. You’ll find the control on the right upper corner, ✌🏼

    • @gementar
      @gementar Před 2 lety

      @@yazminmojica4458 damn

  • @jamb027
    @jamb027 Před 5 měsíci +3

    No products ever made it through trials successfully enough to be a publicly available product in 50 years, then suddenly with only a few months of trials we were promoted as Safe & Effective.

    • @varyolla435
      @varyolla435 Před 5 měsíci

      🤦 Lay off the crack..... - trust me.

    • @jamb027
      @jamb027 Před 5 měsíci

      ​@@varyolla435 What you are saying makes no sense and makes you sound like crack could be a part of your life.
      Name a few mRNA producs that have successfully passed years of trials and gone onto be offered in the marketplace to the public.

    • @varyolla435
      @varyolla435 Před 5 měsíci

      @@jamb027 Still inhaling I see........ Vaccine efficacy does not require years to determine as that bears out very quickly. Other non-safety variables are behind lengthy trials.
      Things like additional trials to test the vaccine in question on other groups of people + the amount of resources devoted to a trial + all the regulatory hurdles as far as licensure of vaccines and so on are why trials can last for years. Researchers will know within a matter of weeks what if any side effects a given vaccine will elicit...... You clearly have no idea of the process here.

    • @jamb027
      @jamb027 Před 5 měsíci +1

      @@varyolla435 So when we were sold Safe & Effective how much success had mRNA medications/medicinal products had in the public marketplace?
      From what I can see there are none that have passed trials successfully enough to be public in 50 years. Unless you can give us the name of a product that has.

  • @jermangarc
    @jermangarc Před 2 lety

    Thank you for this!!! My family sorely needed this info.

  • @Luk317
    @Luk317 Před 3 lety +64

    Wonder what the Graduates of Facebook University make of these facts 😂

    • @Sam-qt5ff
      @Sam-qt5ff Před 2 lety

      Haha never heard that one before. Thanks for the good laugh haha 😂

    • @FOURTEEFIVE
      @FOURTEEFIVE Před 2 lety +1

      Hi, Im a facebook Graduate, here just doing some more study.
      I guess we study at the same place now?

    • @saosintheyperch
      @saosintheyperch Před 2 lety +5

      What? In comparison to those at the CZcams university?

    • @Nicnicnicolas89
      @Nicnicnicolas89 Před 2 lety

      """"""""""Facts"""""""""""

    • @bwenluck9812
      @bwenluck9812 Před 2 lety

      @@saosintheyperch Yeah....

  • @CrashingThunder
    @CrashingThunder Před 3 lety +505

    I feel so grateful for all the scientists and researchers out there doing what they do. I just wish we would spend more of our society's money on research of all kinds so even more could get accomplished.

    • @batarasiagian9635
      @batarasiagian9635 Před 3 lety +41

      Strongly agree.
      In the US this means, among other things, slashing the obscenely bloated defense budget that is equal to the expenditure of the next DOZEN countries combined.

    • @Darkmattermonkey77
      @Darkmattermonkey77 Před 3 lety +11

      A lot of places have tried that throughout human history. Can anyone name a few of them from memory? No... well, that because they were most likely wiped out by another country who put their money into military power and expansion. It’s just how countries work. It’s sad fact of modern life that in order to fund science and progress, you have to put up high walls, people with guns, and big “Don’t mess with us!” Signs. Otherwise, science and scientists wouldn’t stand a chance of making big discoveries. I wish it didn’t work that way, but it does.

    • @eliakimjosephsophia4542
      @eliakimjosephsophia4542 Před 3 lety +26

      No thanks, big pharma is depopulating the planet and making billions in the process.

    • @Darkmattermonkey77
      @Darkmattermonkey77 Před 3 lety +6

      @@batarasiagian9635
      You’re also not considering how many civilians are employed by the government in support of military equipment and organizations. Cutting the budget means put even more millions of people out of work. Nothing is ever as simple as... “oh just slash that budget”. Thinking so is horribly naive.

    • @darylsuess8990
      @darylsuess8990 Před 3 lety +5

      @@eliakimjosephsophia4542 you get it

  • @dastiles1
    @dastiles1 Před 2 lety

    Nice video, very well done and informative. Thank you.

  • @dans4337
    @dans4337 Před 2 lety

    Very informative. Thank you!

  • @simpleasliam657
    @simpleasliam657 Před 3 lety +5

    This was the best video I've seen on this thanks hank

    • @JaneDoe-ip5yl
      @JaneDoe-ip5yl Před 3 lety

      Yes finally a good explanation. Don't we want a little info before getting 💉

  • @mjstudio.416
    @mjstudio.416 Před 3 lety +204

    Well, that makes so much sense now. Perfect timing.

    • @Enclave.
      @Enclave. Před 3 lety +9

      Could have been a LITTLE more perfect, would have been really nice if we didn't have a few months left of time needed to get them working and deployed just right. Course about a year off of perfect timing is still pretty damn close to perfect timing.

    • @mjstudio.416
      @mjstudio.416 Před 3 lety +22

      @@Enclave. feels like everything is planned to force the public to accept something major.

    • @pyrobasplas
      @pyrobasplas Před 3 lety +6

      @@mjstudio.416 exactly what i thought

    • @Howtard
      @Howtard Před 3 lety +13

      @@mjstudio.416 I think it's more that major events force stagnating industries and profit-led capitalists to innovate faster to keep up with a rapid change in priorities/consumer needs.
      I can see why it feels that way to you, but I think you're mixing up cause and effect.

    • @Dragrath1
      @Dragrath1 Před 3 lety +9

      @@Howtard Yep exactly established systems especially industries loathe to innovate quickly if possible opting generally for the safest investments rather than untested "risky" technologies hence such technologies end up in the please fund this box potentially indefinitely unless some threat forces the investors with the money to open this box of untested technologies as they lack fallbacks.
      Wars, pandemics, competition, and or regulations etc. are among the sorts of things that get the ball rolling leading to major progress. Without proper incentives these things tend to just languish for years as proposals catching dust until the research groups behind the projects either give up and move on or die off waiting for money that never comes.
      This is where most human innovation comes to die ideas that never got past the concept design or prototype stages most ideas even good ones just don't get funded because its "too risky" and has been true since the days of classical empires, medieval feudalism, nationalist states, or capitalist investors. Most such projects die at the various pleas for funding stages.
      Rapid innovation only comes when you shake up the establishment without that ideas die away investors not willing to take the effort to sift the chaff from the grain.

  • @northerngirl4924
    @northerngirl4924 Před 2 lety

    Great explanation. Easily understood by anyone. Good work.

  • @luminyam6145
    @luminyam6145 Před 2 lety

    Thank you Hank, that was really interesting.

  • @miroslavmilan
    @miroslavmilan Před 3 lety +193

    Fascinating stuff. This might be the best episode you’ve ever made. It leaves me wondering why do we need to watch CZcams to receive vital information that should really be distributed by the mass media and health authorities, to help avoid spreading misinformation, conspiracy theories and fearmongering. It has certainly helped dispel some of my concerns about these “rushed” vaccines, and it makes me much more comfortable to get a shot once my turn comes.

    • @loryndabenson5840
      @loryndabenson5840 Před 3 lety +43

      Yea this needs to be aired on a segment of every news stations right now. I trusts this information a lot more than what I'm seeing on tv.
      Especially as an African American I see the pandering to black people they're doing trying to convince more of us to get the vaccine Cuz they know the medical community has a bad rep with black Americans. However seeing my information straight forward like this with a little scientific breakdown that includes material most people SHOULD'VE learned in at least one biology class, I'm more likely to understand HOW the vaccine was pushed through and that it is most likely safe for most people. I also trust this particular source already Cuz I've been watching for years and they tend to be as neutral as possible when it comes to these more serious topics. Which I really appreciate.

    • @fghsgh
      @fghsgh Před 3 lety +11

      A lot of people would not care, listen, or understand. You know, because people are stupid.

    • @johnm5928
      @johnm5928 Před 3 lety +9

      So you don't question anything he said?

    • @fghsgh
      @fghsgh Před 3 lety +20

      @@johnm5928 Everything he said sounds entirely logical and scientific. He also provided a bunch of scientific sources in the description. Of course there is a chance everything is wrong, that's how science works, but the entire goal of science is to "make a less wrong claim next time", and it has worked so well till now that you can be 99.9999999% certain that this is correct (according to statistics and p values and such). And it's better than the alternative of "AAH WE'RE ALL GONNA DIE"

    • @johnm5928
      @johnm5928 Před 3 lety +11

      @@fghsgh That's sort of my point. We are presented day-in and day-out with studies that are conglomerated to tell a story - by the media, by politicians, any by youtubers. Most of the time, they provide sources. Do you ever read their sources? Do you ever do your own research to verify what they are telling you? Or do you sit back, like in this case, and absorb without question everything presented to you because it "sounds logical"? I'm not saying its wrong, nor am I saying it is likely false, but to take a youtuber's short presentation as the arbiter of truth is, well, frankly naive.

  • @HuevoBendito
    @HuevoBendito Před 3 lety +389

    Mfw, this video does a better job than my med school of giving an overview of mRNA vaccines

    • @dynomar11
      @dynomar11 Před 3 lety +13

      That's kinda scishow's thing. Even crash course is more informative and it's literally a crash course

    • @reecebailey3513
      @reecebailey3513 Před 3 lety +12

      Not only better than med school cheaper too 😂

    • @timeWaster76
      @timeWaster76 Před 3 lety

      When did you go to med school ?

    • @dynomar11
      @dynomar11 Před 3 lety +1

      @@timeWaster76 I think the more pertinent information is where.

    • @nuclearcatbaby1131
      @nuclearcatbaby1131 Před 3 lety +1

      mRNA liposomes shouldn’t be used for vaccines. They were designed for gene delivery which means they go out of the way to avoid triggering an immune response. The only reason it triggers an immune response at all is because most people already have some immunity to the spike protein (it’s similar to that of the common cold coronavirus).

  • @neilyoungman9814
    @neilyoungman9814 Před 2 lety +2

    I liked the jump from referencing the Apollo missions to ".. science is incremental ... it never works in a vacuum"

  • @maridevskey
    @maridevskey Před 2 lety

    Great and very informative video. Hard work

  • @nankinink
    @nankinink Před 3 lety +21

    Sometime earlier the pandemic, I had an insight that why we wont just skip the whole process of weakening the virus/bacteria and sent its RNA to produce the antigen. Heck, a quick google made me realize all that this was in the works and I felt so good seeing that I wasnt dreaming about something wrong.

    • @bobingalls4643
      @bobingalls4643 Před 3 lety

      in World News
      'Nobel Prize Winner French Virologist Luc Montagnier Explains How COVID-19 Vaccines Are Creating Variants'
      "Nobel Prize winner French Virologist Prof. Luc Montagnier in an interview has made a startling claim that the COVID-19 vaccines itself are creating variants. He said that epidemiologists know but are “silent” about the phenomenon, known as “Antibody-Dependent Enhancement” (ADE)."
      rightedition.com/2021/05/22/nobel-prize-winner-french-virologist-luc-montagnier-explains-how-covid-19-vaccines-are-creating-variants/

  • @nicoleonfeels
    @nicoleonfeels Před 3 lety +156

    I suspect time travel is the reason here.

    • @bromicorn
      @bromicorn Před 3 lety +16

      @@Chris-rg6nm classic Nicole amirite

    • @SilverScarletSpider
      @SilverScarletSpider Před 3 lety +5

      You smart Nicole

    • @horacegentleman3296
      @horacegentleman3296 Před 3 lety +13

      Oh Nicole, you can't control your crippling crack cocaine addiction, but you can sure tell a joke.

    • @FrozEnbyWolf150
      @FrozEnbyWolf150 Před 3 lety +4

      And I just know a WHO Doctor was involved.

    • @Triairius
      @Triairius Před 3 lety +1

      Technically, without time travel, there wouldn't be a reason.

  • @Roedygr
    @Roedygr Před 2 lety

    Your best show yet!

  • @tintinsmythe5837
    @tintinsmythe5837 Před 2 lety +6

    "just in time" 😂😂

  • @grinreaperoftrolls7528
    @grinreaperoftrolls7528 Před 3 lety +84

    This is the kind of stuff that encouraged me to switch majors from physics to genetics and virology. I LOVE IT

    • @journeyinthemoment
      @journeyinthemoment Před 3 lety +1

      A most important video to watch and share - Mass Vaccination in a Pandemic - Benefits versus Risks: Interview with Geert Vanden Bossche" on CZcams
      czcams.com/video/ZJZxiNxYLpc/video.html
      Geert Vanden Bossche Ph.D., is an internationally recognized vaccine developer having worked as the head of the Vaccine Development Office at the German Centre for Infection Research. Coordinated Global Alliance for Vaccines and Immunisation's Ebola Vaccine Program and contributed to the implementation of an integrated vaccine work plan in collaboration with Global Health Partners (WHO, Bill & Melinda Gates Foundation, CDC, UNICEF), regulators (FDA) and vaccine manufacturers to enable timely deployment or stockpiling of Ebola vaccine candidates. Highlighting the principle of using a prophylactic vaccine in the midst of a pandemic. Likely to create more viral variants in the process. Sharing his perspective on mass vaccination in COVID-19.

    • @darkphoenix7225
      @darkphoenix7225 Před 3 lety +8

      @@journeyinthemoment Geert Vanden Bossche, the guy posts his articles to twitter and his own website rather than any peer reviewed scientific journal? yeah, that's not sus at all. Why would you think people who watch sci-show would listen to some dude that talks about his data that isn't vetted through other peers? Seriously, do you think people in this youtube community are that stupid? You do realize he called COVID "harmless" right? Yeah, maybe if you ignore the thousands of people dead it's harmless. He's a tool, a tool to get money from the anti-vax crowd. He wants to use his own solution, which isn't made yet, isn't in production, hasn't been tested, ect. It doesn't even have a patent.
      He's a fringe dude that works in the virology field and talks as if he's the only one that talks about variants due to vaccinations, when that's talked about all the time. Seriously, go look up those key words into a scientific journal search engine. Plus, his hypothesis completely forgets to talk about why viruses go extinct. A pressure in the environment changes radically that causes the virus to not be able to evolve fast enough. He doesn't know how likely a coronavirus can change it's spike proteins. If we vaccinate before this can happen, then no his hypothesis wouldn't happen.
      Going "well this can happen" without any data of how likely the danger is rather silly when you want to halt vaccinations against a deadly virus. He should've brought data to the table if he wants vaccinations to stop. He hasn't so I assume he either doesn't have that data or is keeping it to himself as it would out himself as a fraud.
      It's like saying "well seatbelts might be more dangerous than X." Cool, get the data for injuries on a crash dummy and then get the injuries for X on the crash dummy and compare the two. Just because you think you have a better solution, doesn't mean we should stop using our current solution when there is absolutely no data presented.

    • @madisonc2410
      @madisonc2410 Před 3 lety +3

      @@darkphoenix7225 Really...how ridiculous!!! There are plenty of others saying the very same thing. A mother had her second Pfizer shot then breastfed her five month old baby boy...baby died the next day from blood clots!!! It sure sounds like a very safe vaccine if you want a dead baby! There are a lot of deaths and thousands of side effects but let’s mass vaccinate everyone even though most people have little to NO risk = insane!!!

    • @darkphoenix7225
      @darkphoenix7225 Před 3 lety +7

      @@madisonc2410 *States there are plenty of others, doesn't give any names or data, just states it as if anyone should take your word for it*
      Cool story bro

    • @SuperOmnicronsj44
      @SuperOmnicronsj44 Před 3 lety

      Yes, especially the DEATHS attributed to it and illness (blood clots) . But hey, cant make an omelette without breaking a few eggs (LIVES)

  • @jofis912
    @jofis912 Před 3 lety +4

    Great job explaining. It answers a lot

  • @PhoebeJaneway
    @PhoebeJaneway Před 2 lety

    So interesting and so important! Thanks!!!

  • @belvedere92
    @belvedere92 Před 2 lety +1

    I had 2 doses of AZN's vaccine, last one in June. About 6 weeks later I noticed that the nail on one toe on the left foot was turning into a claw (I am serious) and similar but delayed action on the right toes. Is there reason to tie these two events together?

  • @dylanporter8105
    @dylanporter8105 Před 2 lety +42

    Conspiracy theorists: so what you're saying is covid was 50 years in the making 🤔

    • @sahirde
      @sahirde Před 2 lety +5

      Don't give them ideas LMAO

    • @babajamiaco
      @babajamiaco Před 2 lety

      You may be closer to the truth thank you're probably suspecting, as those RNA splicing/combining technologies used in Wuhan lab and those used for creating mRNA are not that far apart from each other...

    • @j2times2006
      @j2times2006 Před 2 lety

      It was the illuminati! They created it using the haarp system so that they could push you to get the vaccine which has (Jessie Ventura voice) MIND CONTROL properties in it to begin the new world order!!!
      Sounds legit I know. 😁

  • @Tundra-ec3ii
    @Tundra-ec3ii Před 3 lety +60

    Crab Check:
    No. There are no crabs in this video.

    • @moritzweber907
      @moritzweber907 Před 3 lety +4

      Sad

    • @Triairius
      @Triairius Před 3 lety +6

      Nope, the virus hasn't carcinised yet.
      Yet.

    • @TheRealFobican
      @TheRealFobican Před 3 lety +2

      Because everything keeps evolving into a crab?

    • @uptown3636
      @uptown3636 Před 3 lety +2

      We need to journey to the microcosmos to see if there are any microscopic crabs in this video.

    • @goldendoqqs7685
      @goldendoqqs7685 Před 3 lety +1

      Good news, they just posted a video about crabs today

  • @christopherbrzezinski256

    Your show was just recommended to me and now here I am. I’m glad I stopped by.

  • @Yupppi
    @Yupppi Před 2 lety

    I missed this for a year despite regularly watching scishow. Nice demystifying.

  • @pipbaxter5286
    @pipbaxter5286 Před 3 lety +5

    Simply and clearly explained, thank you.

  • @tomcollins5112
    @tomcollins5112 Před 2 lety +25

    Whenever I hear about "twisted proteins", I think of prions and Mad Cow disease.

  • @matormscchannel4328
    @matormscchannel4328 Před 2 lety

    ..I appreciate the information..Really informative

  • @petethomas1765
    @petethomas1765 Před 2 lety +94

    Scientist's learned a lot in the past two decades since sars cov 1. They failed with that one and luckily it went away but glad they kept researching. People seem to think this vaccine was all of a sudden because they're too lazy to read. Thanks for sharing this information.

    • @kellybuzby4752
      @kellybuzby4752 Před 2 lety +31

      I don’t think it’s laziness most people know the MRNA technology has been around for a long time. The vaccine is new, the technology hasn’t been introduced into the human body before this, and it’s not 100% safe and effective and doesn’t stop or slow the spread of the virus (which was not how it was sold to the public) so there are a lot of issues when considering vaccine hesitancy mostly dealing with transparency.

    • @petethomas1765
      @petethomas1765 Před 2 lety +19

      @@kellybuzby4752 mrna has been studied since the 60s, if you ask anyone about it they'll tell you its new because not many people actually read. Its not nearly as new as you might be told depending in who you talk to or your source on the internet as they are often bias. Human studies were done in the 80s, they didn't quite know how to get the liposomes to last making the cells lose function. 40 years of practice since then so humans have made quite a bit of progress. We had sars cov 1 in 2001, 2 decades of time to study on that alone with technology advancing much further since the initial. 187million people have the vaccine in america, 3 deaths from complications which is way under the bet if you're just trying something "new". I have been vaccinated for 6 months as well as the entire family with 0 complications. Consider the vaccines you already have that are mandated for schools jobs ect. They all had to begin with some form of trial, some form of acceptable function ratio, then phase 3 for the mass. In the 1890s it took 2 years for a polio vaccine. Now consider technology advancing at the rate it has for the past 120 years and the fact that the entire world was feeling threatened by something they had not collectively experienced.

    • @gabrielcat72
      @gabrielcat72 Před 2 lety +8

      Well they did release it 2-3 years before full approval under emergency measures. A lot of complications occured, severe ones in very healthy young people sadly. But overall, it might've been worth it. Time will tell

    • @MrBeGorda
      @MrBeGorda Před 2 lety +7

      @@petethomas1765 thank you for using your body to test an experimentation vaccine lets see how it goes on you first

    • @88marome
      @88marome Před 2 lety +7

      @Aleix There haven't been any negative effects for billions of people.

  • @pinkijs93
    @pinkijs93 Před 3 lety +31

    Thank you so much for making this! I was having a few fearful family members and I needed something that could show them it isn't that new of a technique and it is as safe as a vaccine can be. You did a great job at doing that in a simple way.

    • @seshp2440
      @seshp2440 Před 3 lety +7

      It's not and this is misleading. Look up Dr. Robert Malone, who invented the tech. And he invented it 30 years ago, not 50. I would not share this as any kind of authority on the topic. Go directly to the expert if you want real answers.

    • @pinkijs93
      @pinkijs93 Před 3 lety

      @@seshp2440 Thank you for your response but I wasn't looking for a high level source of information for a study or paper. I realize that some things aren't a 100% accurate or perfectly presented. This is a simplified way of explaining some very complicated matters for an average layman. I think they did a wonderful job at that. What real inaccuracies in their explanation have you found other than details like dates?

    • @seshp2440
      @seshp2440 Před 3 lety +8

      Ouch. Umm... this is hard to reply to. Understand that you went looking for something that you could show to your relatives that are fearful of a new tech. You found this and without cross referencing, sourcing at all or knowing anything about its validity, you have decided that this is a good piece of science or information. That's called cognitive dissonance. It's the opposite of science. Also understand that videos like this are made for people just like you. This whole video is ripe with misrepresentation in the history of this tech and its implications. I have left you the name of the creator, who has several videos and interviews out describing in lay terms what the history of this tech is and his involvement in it. That's more than enough of a bread trail for you to find the correct info, or at least cross reference this video to see how it holds up. As I said, go to the expert for info. Not ramdon youtube videos with no sources and not random strangers in the comments. But I digress. If all you want is ammo to combat your hesatitant relatives with, than all this is of no use to you.

    • @pinkijs93
      @pinkijs93 Před 3 lety +9

      @@seshp2440 2:10 he says that the mRNA vaccine technique came up around 1990 and that is correct with what you say and the Dr you are referring to says. He repeats this information around 5:36. The title only says that the start of the vaccine was 50 years ago. This refers to other uses of mRNA. Vaccines aren't the only way to insert mRNA into a cell or body. So, that isn't an inaccuracy. Your expert is one of the people who invented the mRNA vaccine technique but that doesn't mean he knows everything about the current vaccines.
      Technology moves very fast and most companies keep the details of their work confidential. So, there is no way that he would be able to know all the ins and outs. He knows them based on the theory of those vaccines and based on the knowledge that he has as an expert in the field. That does not make him an all knowing person when it comes to these specific vaccines. Citing one specific person without giving any factual inaccuracies with what the person is saying, does not make you come across as a very informed person either.
      I am NOT a person who knows nothing about vaccines or biotechnology for that matter. I am a person who tries to inform myself about a subject before going out and looking for a simplified form of that information for people without a medical background. The doctor that you cite throws around many difficult words and his interview with buddies who do nothing but agree with him and vice versa is over 3 hours long. That isn't very accessible. If he truly wanted to share his knowledge and concerns, including with other experts in the field, there would have been many ways to do so.

    • @pinkijs93
      @pinkijs93 Před 3 lety +3

      @@seshp2440 You are making assumptions all on your own. Who says I did not fact check. I can't find any real inaccuracies. Only simplified explanations that might not cover all that it means. That is why I asked you what inaccuracies you have found. I have found over a dozen scientific publications, some published not even two weeks ago, I have looked at national databases for drug safety and side effect registrations, that all agree with what he says. If you can give me any articles or any source of information other than facebook that says otherwise, I will be happy to read those as well.
      pssjournal.biomedcentral.com/articles/10.1186/s13037-021-00291-9
      www.pharmaceutical-technology.com/comment/covid-19-mrna-vaccines-disinformation/
      www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/mrna.html
      immunizebc.ca/ask-us/questions/are-there-long-term-side-effects-caused-mrna-covid-19-vaccines-how-do-we-know
      www.cdc.gov/coronavirus/2019-ncov/vaccines/recommendations/pregnancy.html
      www.icsi.org/covid-19-vaccine-faq/do-the-mrna-vaccines-cause-infertility/
      www.healthline.com/health-news/dont-let-misinformation-about-fertility-and-covid-19-vaccines-stop-teens-from-getting-the-shot#Combatting-fears
      www.hopkinsmedicine.org/health/conditions-and-diseases/coronavirus/covid-19-vaccines-myth-versus-fact
      pubmed.ncbi.nlm.nih.gov/33882218/
      www.ncbi.nlm.nih.gov/pmc/articles/PMC7927763/
      pubmed.ncbi.nlm.nih.gov/33985514/
      www.ncbi.nlm.nih.gov/pmc/articles/PMC8163337/
      www.rivm.nl/en/covid-19-vaccination/vaccines/pregnancy
      www.lesswrong.com/posts/7NoRcK6j2cfxjwFcr/covid-vaccine-safety-how-correct-are-these-allegations
      horizon-magazine.eu/article/five-things-you-need-know-about-mrna-vaccine-safety.html
      www.lareb.nl/pages/update-van-bijwerkingen
      Here you have a sample of articles and websites that tell you what we currently know. Some in scientific terms. Others in more accessible terms.

  • @vhaalgorn
    @vhaalgorn Před 3 lety +95

    Science is so beautiful.

    • @DoctorX17
      @DoctorX17 Před 3 lety +7

      A wonderful mix of the work of generations, and the dash research of scientists across the world.

    • @HaHa-gg9dl
      @HaHa-gg9dl Před 3 lety +6

      @@tuckerbugeater Sure whatevs

    • @runces5563
      @runces5563 Před 3 lety +1

      Science is weird and beautiful at the same time

  • @leader7418
    @leader7418 Před 2 lety

    This is absolutely great information.

  • @DropYoutube
    @DropYoutube Před 2 lety +22

    So technically it's not a vaccine.

    • @JustAnotherAccount8
      @JustAnotherAccount8 Před 2 lety +3

      It is, here's the google definition of a vaccine - "A vaccine is a biological preparation that provides active acquired immunity to a particular infectious disease."
      mRNA does just that.

    • @blackcirclepolkadot2618
      @blackcirclepolkadot2618 Před 2 lety +8

      I consider this a seasonal vaccine. I prefer seasonal shot, really. Because you will be taking it every year if you want to. A true vaccine (in my opinion) stops transmission. Like measles and smallpox. This is what most people think of first when they hear “vaccine.”

    • @blackcirclepolkadot2618
      @blackcirclepolkadot2618 Před 2 lety

      And that is the Wikipedia definition ha. Google uses Oxford.

    • @JustAnotherAccount8
      @JustAnotherAccount8 Před 2 lety +1

      @@blackcirclepolkadot2618 Doesnt matter what you consider vaccines, because scientists say otherwise

    • @migueldias1955
      @migueldias1955 Před 2 lety

      yeap.

  • @CptnHammer1
    @CptnHammer1 Před 2 lety +11

    yes brother! I love how hyped you are about this! :D get hyped!

  • @CHINGONJUICE
    @CHINGONJUICE Před 3 lety +303

    Wow cleared up sooo many questions and myths floating around on social media. Thank you

    • @lupo10
      @lupo10 Před 3 lety +43

      To be fair, it’s a myth that this tech works.
      They haven’t finished testing it yet, let’s revisit next year when they’re telling you to get a second shot.

    • @dahbajanman7044
      @dahbajanman7044 Před 3 lety +70

      @@lupo10 Just because you may need a booster that doesn't mean mRNA doesn't work effectively.

    • @CHINGONJUICE
      @CHINGONJUICE Před 3 lety

      @@wonderwoman7023 yes, if you know something do enlighten me please

    • @sharkymoon422
      @sharkymoon422 Před 3 lety +9

      What about the nanobots?!

    • @lupo10
      @lupo10 Před 3 lety +5

      @@sharkymoon422 haha I don’t know what they are or why they’d want to implant them 😂

  • @Quesofoods
    @Quesofoods Před 2 lety

    After listening these videos i am becoming top fan of scishow ❤️❤️❤️ welldone team keep rocking

  • @Blakrex
    @Blakrex Před 2 lety

    Very cool, great information for a lot of people.

  • @scarletthayle4822
    @scarletthayle4822 Před 3 lety +74

    im in my post work exhausted melancholy legit had to look at the calendar after reading this title/description

  • @DrReginaldFinleySr
    @DrReginaldFinleySr Před 3 lety +6

    Beautifully done gang. And this is just the beginning.

    • @bobingalls4643
      @bobingalls4643 Před 3 lety

      yeah, the beginning of destruction. You people are so funny, you think the elite technocrats and their bought off scientists actually care about humans. This is about depopulation.

    • @scienceium5233
      @scienceium5233 Před 2 lety +1

      @@bobingalls4643 rip

    • @DrReginaldFinleySr
      @DrReginaldFinleySr Před 2 lety

      @@bobingalls4643, lol. So when is this supposed to happen again? At current, thanks to vaccines, Covid-19 deaths have plummeted and pregnancies are on the rise. Looks like the "elite technocrats" failed again! Darn!

    • @bobingalls4643
      @bobingalls4643 Před 2 lety

      @@DrReginaldFinleySr more lies from mainstream media and Fauci. Some hospitals have reported that 60% of their covid infected patients were vaccinated. The mRNA injections DO NOT stop you from getting covid. The idea is that they will reduce the symptoms for those vaccinated.

    • @dhalsim-1
      @dhalsim-1 Před 2 lety

      @@DrReginaldFinleySr
      The mainstream media (run by vested interests) will tell you anything and you'll go for it. Although they don't seem too concerned about Dr Fauci being questioned in the Senate about funding the creation of this virus.

  • @D3Sshooter
    @D3Sshooter Před 2 lety

    Good video, down to the point

  • @kellycandacyjoseph3776

    This was an awesome presentation 👏 👌

  • @thetajuice
    @thetajuice Před 2 lety +18

    1:35
    Just gotta say if I saw this poster I defiantly wouldn't think it's about antigens.

  • @synthelia7564
    @synthelia7564 Před 3 lety +63

    My mother has been very anti-covid vaccine because "they rushed the process" and "they can't even make a vaccine for the common cold". We've been bickering over it for months, and I plan to show her this video tommorow. Hopefully she'll change her stance, but even if she doesn't at least she'll be making an informed decision. Wish me luck 🤞
    Update: She didn't really care, and it doesn't seem to have changed much.

    • @cloudpoint0
      @cloudpoint0 Před 3 lety +26

      They could make a vaccine for a common cold virus if they wanted. In fact, COVID-19 is a common cold virus but it is going through its ‘terrible twos’ phase now. Generally it just isn’t worthwhile to make a common cold vaccine.
      More than 200 different viruses are known to cause the common cold (multiple rhinoviruses especially). Finding a vaccine for just one of these likely has little economic value, and you are already immune from it for years after one exposure (depending on how many antibodies you generated and retained). Influenza is worth finding vaccines for since there are fewer strains circulating and it is nastier than common cold viruses. Genetic drift will eventually make the present COVID-19 vaccines ineffective but they worth having at this point in time.

    • @CarlosBeo
      @CarlosBeo Před 3 lety +8

      Good luck. One of my uncles is a full on conspiracy theorist. It's so frustrating...

    • @futuristiccat5636
      @futuristiccat5636 Před 3 lety +19

      Lol wait until you find out you can’t sue the companies who made the vaccine. Take it at your own cost. We warned you. Many people I know have gotten very bad side affects like vomiting, headaches, soreness, weakness, fatigue etc and some haven’t had any side affects. All I’m saying is it’s your body your choice.

    • @futuristiccat5636
      @futuristiccat5636 Před 3 lety +17

      @@CarlosBeo I trust him. Better to be sceptical with the government nowadays

    • @CarlosBeo
      @CarlosBeo Před 3 lety +6

      @@futuristiccat5636 That is only the case in the US. In the EU vaccine makers are liable.

  • @brandonhinojosa4202
    @brandonhinojosa4202 Před 2 lety

    Amazing video!

  • @captainbc52
    @captainbc52 Před 2 lety +8

    I wonder if they developed the MRNA vaccine for covid at the same time they were developing covid itself...🤔🤔🤔

    • @auschwitzwelcomecommittee3593
      @auschwitzwelcomecommittee3593 Před 2 lety

      Negative, the clot-shot bioweapon was created years before the clot-virus bioweapon. They spent years scheming out a way to get people to take the clot-shot voluntarily, and the only thing they could come up with was a virus.

  • @LuinTathren
    @LuinTathren Před 3 lety +86

    Fantastic video! I wish everyone could watch this. Thanks, Hank and everyone else at SciShow!

    • @Darkchylde50
      @Darkchylde50 Před 3 lety +6

      You can't fix stupid nor can you teach ignorance. The people who are against this will remain that way just because it's divisive & gets them all tribal about it. It's a US vs Them Phenomenon just to feel special. Hurrah humanity.... This video would only benefit those who already think like you.

    • @dr.victorm.vieira2836
      @dr.victorm.vieira2836 Před 3 lety

      Play GOD.. and NO Liability!!

  • @jp4431
    @jp4431 Před 3 lety +13

    Anti-piracy slogans: you wouldn't download a car would you?
    Us today: oh you can download more than cars now

  • @pinkpurple7314
    @pinkpurple7314 Před 2 lety +6

    As a geneticist, videos like these make me happy. Accurate, informative, and will hopefully ease some people's fears. Nicely done yet again!

    • @patrickdisalvo6532
      @patrickdisalvo6532 Před 2 lety +2

      This video had the opposite effect on me. It heightened mine.

  • @FilterYT
    @FilterYT Před 2 lety +13

    Thanks for another amazing video, it would be nice to explain to people how long the mRNA is active in the body and how long the foreign proteins remain in the body, also the mechanisms that would eventually breakdown and remove those proteins. This is an fantastic explanation and I will be referring it to friends and family. Thank you.

  • @EmilyJelassi
    @EmilyJelassi Před 3 lety +14

    Thank heavens for all of those researchers and scientists who did all the work so we can have the vaccines today! Very informative and interesting video 😊

  • @extreme8808
    @extreme8808 Před 3 lety +8

    That's probably the best episode yet. Now I can say I completely understand not just how the mRNA vaccines work, but actually how they are able to achieve robust CD4+ and CD8+ response, compared to the adenovirus-based vaccines, which simply cannot achieve that. Even tough you haven't address that in the video, it's pretty clear when you think of it. KUDOS! :)))

  • @BCxFOREVER
    @BCxFOREVER Před 2 lety

    i love scishow!!!!! this is so cool!!!

  • @alpsconstructions2208
    @alpsconstructions2208 Před 2 lety +14

    This video was very informative. The last bit though, It’s likely they will keep working? Does it need more testing? Thanks 😊

    • @raystanczak4277
      @raystanczak4277 Před 2 lety +4

      That part was a little unclear. I don’t think he was referring to this vaccine, which is close to full approval, and was the culmination of decades of work. He’s hoping that the mRNA process works as well on other viral and bacterial diseases, and even some cancers, which are now undergoing human trials.

    • @Goldengirl48
      @Goldengirl48 Před 2 lety +2

      No I don't think so. Unless you have a problem with your immune system the vaccine should be effective for a very long time. But being a virus, they mutate over time and become a different entity or a different virus altogether. Then your immunity may or may not recognize the new virus. Much like cancer cells which also mutate, it make it difficult to treat. For example, a cancer cell that started out in the lung metastasized to the liver but even though you treat the lung cancer, the mutation of the liver cancer is different and may not respond to the lung treatment because of the mutation. Plus the cancer may not been caught in time to stop further spread or metastasis of the to other organs. That's why cancer is so difficult to treat.

    • @ninij9692
      @ninij9692 Před 2 lety

      @@Goldengirl48 like influenza....

    • @Enforcer_WJDE
      @Enforcer_WJDE Před 2 lety

      @@Goldengirl48 Exactly.
      Cancer is also different for everyone that's why you can't take the same treatment even though two people have the same type of cancer because their bodies are different and the disease develops differently. Something people don't understand.

  • @bethan013
    @bethan013 Před 3 lety +195

    “DNA and RNA are just strings”
    Cromatin: am I a joke to you?

    • @MisterTutor2010
      @MisterTutor2010 Před 3 lety +19

      rRNA and tRNA would say the same.

    • @alan4sure
      @alan4sure Před 2 lety +1

      By using the way overused yt comment, I can guess both your age and IQ.

    • @bethan013
      @bethan013 Před 2 lety

      @@alan4sure Alan, is everything OK?

    • @alan4sure
      @alan4sure Před 2 lety

      @@bethan013 "am I a joke to you?" is way overused. It was stale 2 yrs ago. I don't know where it originated, but maybe some video or game that makes a big impression on young people.

  • @Robert-yc9ql
    @Robert-yc9ql Před 3 lety +27

    I absolutely LOVE how scientific advancement is cumulative.
    This demonstrates that fact very clearly.
    Nicely done.

  • @marcus9434
    @marcus9434 Před 2 lety

    EXCELLENT video!!!
    Subscribed.
    🔬⚛️😎

  • @Raptor302
    @Raptor302 Před 2 lety +1

    Really fascinated to see how these vaccines get mass produced- the rubber meeting the road part where careful research runs into brute logistics.

  • @gugolsebis5604
    @gugolsebis5604 Před 3 lety +4

    Can you tell me what is the proper medical defenition ( FDA ),what's the meaning of the words :
    Safe and effective..

    • @johndododoe1411
      @johndododoe1411 Před 3 lety

      Those words are bureaucratic speek for safe enough and effective enough, compared to the illness.

  • @damianm-nordhorn116
    @damianm-nordhorn116 Před 3 lety +17

    "ALL science is INCREMENTAL".
    .. and complex problems and solutions need to be broken up into smaller, less complex pieces, to solve them and to make this understandable for common people and demonstrate how this is not magic at all.
    That's THE message/word that has to be spread around this often ignorant 🌍.

  • @stijnvth
    @stijnvth Před 2 lety

    Dude, i appreciate this clear info.

  • @ChalkandIron
    @ChalkandIron Před 2 lety

    Great content

  • @andrewbest5854
    @andrewbest5854 Před 3 lety +20

    Thanks for the well made, interesting video. But it raises almost as many questions as it answers. Eg. if mRNA is packaged in a lipid nanoparticle, how can it act as an adjuvant? Wouldn't it be hidden from the immune system? I would assume that undamaged lipid nanoparticles are very poorly immunogenic, and this seems to be the whole point of packaging it, so that it doesn't get destroyed before it can be absorbed by cells.
    Also... if it's packaged in a lipid nanoparticle, does it matter whether it is in modified mRNA or unmodified form?
    Further - it's presented as if mRNA vaccines saved the world in this pandemic. But the Astra Zeneca vaccine, the Chinese and Russian vaccines were all produced in a similar time frame with similar efficacies (well at least for Astra Zeneca anyway). In the grand scheme, most of the world is going to get a non mRNA vaccine. So did mRNA vaccines really change the course of the pandemic? Or did they help a bit? Seems like most of the promise of mRNA vaccines will be going forward, eg. for malaria.

    • @andreasiwak2651
      @andreasiwak2651 Před 2 lety +12

      The mRNA cannot diffuse though the cell plasma membrane and degrades before it can be delivered into the cell and translated. The lipid nanoparticles break down and release the contents, and these nanoparticles can be engineered to release the mRNA when a specific set of conditions is met, e.g. it degrades at a specific pH in some cells. So while the mRNA is hidden from the body until a set of physiological conditions are met, it absolutely does invoke an immune response when it is translated and a foreign protein is formed, resulting in the production of antibodies by the immune system. Additionally, lipid nanoparticles have an adjuvant nature and adjuvants can also be encapsulated in the nanoparticle to co deliver with the mRNA.

    • @sunspot42
      @sunspot42 Před 2 lety +3

      mRNA vaccines absolutely changed the course of the pandemic. When development started on the Astra Zen and Johnson & Johnson viral vector vaccines people had no idea of either of them would be safe and effective. The Moderna and Pfizer vaccines provided two more candidates to run thru testing. As it turns out all four were safe and effective, but there was no guarantee of that headed into the pandemic.

    • @garyedwards5345
      @garyedwards5345 Před 2 lety +4

      @@sreedharreddypochana2892 I think you're on the wrong channel.

    • @jacinthclifton636
      @jacinthclifton636 Před 2 lety

      @@sreedharreddypochana2892 I completely agree.

    • @sreedharreddypochana2892
      @sreedharreddypochana2892 Před 2 lety

      @@jacinthclifton636 Hi namaste🙏 to all.
      Now I am sharing few title's from my side to all world.
      Title's
      1) All our health is governed by all our hands.
      ( Surrounded by good environment, nature, sunlight) .
      2) where is the science ends & what's the silence start speek about inner engineering.
      3) Knowledge is not repeated by known things& knowledge is repeated by false documents.
      ( Fail-First attempt in learning).
      4) What do you mean Enthothiasism to work & Enthothiasism to compassion it.
      5) what's WHO'S definition- World Health Organization or World happy ness organization.
      6) what's the life span is equal to life expectancy.
      7) Eat when hungry & drink when thirsty & eat less stay healthy.
      What's Autoimmune disease & liver alcoholic cirrosis, Nutritional immune deficiency syndrome ( NIDS).
      08) 3 more things now I am remembering to all world.
      A) I love you - I means illness.
      B) you love me.
      C) we love all - we means wellness.
      09) Now a days all doctors & rmp's treated report's ( Except few doctors) not patients.
      What doctors don't get study in medical school.
      What's difference between Disease & drug ( All diseases invented it sell a medicines it creates more customer's & spoiled all life) .
      10) All of us don't never try to make money in the sickroom s( Where is real air available in all A/C Rooms)
      Money is brought or cause for all diseases to all world.
      Nowadays All Doctors treated report's & Not Patients.
      What Doctors Don't get study in medical school.
      All Doctors & softwares don't never try to make money in the sick room( Where is real air including with freedom available in All hospitals and Pharma & software companies).
      Chemical Drugs including air pollution can damages to all our body organs.
      Medicine is so bad in 1823 .
      11) If we ( All World)Don't Believe a Concious Population & More and More Technology , Medical Means More and More Trouble.
      If we ( All World)Believe a Concious Population & More and More Lovely Nature🌿🍃 Means & More and More Lovely , Convinent & Enjoyment to all World.
      (All is always well with love❤ ly enjoying with nature🌿🍃🌿🍃🌿🍃 & Sunlight☀️☀️☀️☀️& Sunset🌅🌅🌅.
      12) Now I am remembering one poem to all world.
      Poem
      Old is gold & New is worst,
      The all world is going to worst situation,
      Little be sea a All Nature to ours,
      Fanally at what time all of them Near to nature & love to Nature🌲🌳🌴🌲🌳🌴🌲🌳🌴🌲🌳🌴🌲🌳🌴🌲 🌳🌴&Sunlight☀️☀️☀️☀️ Definitely all is always well with lovely enjoying.
      Otherwise 200 Persent the world is going to worst conditions including coming generation.
      What's the Best Enjoying booster to all world Means-FREEDOM Including LOVE.
      What's freedom, Where is freedom available & why is freedom, How is freedom available to All world or Planet 🌍
      Nowadays all of them why spoiled all our family life Means.
      Now I am remembering few title's to all world medical staff including Pharma staff & Technology staff.
      Hi Namaste to all Medical Staff , Technology staff to all world.
      Title's
      When the mind is not in the brain how can run 🏃💨 our all body organs.
      All of us don't never try to make money in the sickroom s( Where is real air available in all A/C Rooms)
      Money is brought or cause for all diseases to all world.
      Nowadays All Doctors treated report's & Not Patients.
      What Doctors Don't get study in medical school.
      All Doctors & softwares don't never try to make money in the sick room( Where is real air including with freedom available in All hospitals and Pharma & software companies).
      Chemical Drugs including air pollution can damages to all our body organs.
      Medicine is so bad in 1823 & Medicine, software is a one type of business to all world & it Creates more Customers & spoiled all life.
      At what time failure of Scientific research & Technology ( World Health organization & World Technology Organization- Both of them making money & Spoiled all life)
      &
      Successful of Nature loving enjoying centers( Including naturally available Air, Water💧💧💧, Food🍲🍲🍲) with lovely Nature 🌿🍃🌿🍃 & Sunlight 🌕🌕🌕🌕 definitely all is always well.
      What is my final conclusion to All world ( Always I am feeling all Planet is a my whole body or my whole Lovely enjoying family)Means -At what time all of them near & love to nature🌲🌳🌴🌿🍃 & sunlight 🌕🌕🌕 & Sunset🌅🌅🌅 Definitely all is always well with lovely enjoyment & entiretinement)...
      Two More thinks Now I am Remembering to All World.
      1) If we ( All World)Don't Believe a Concious Population & More and More Technology , Medical Means More and More Trouble.
      2) If we ( All World)Believe a Concious Population & More and More Lovely Nature🌿🍃 Means & More and More Lovely , Convinent & Enjoyment to all World.
      (All is always well with love❤ ly enjoying with nature🌿🍃🌿🍃🌿🍃 & Sunlight☀️☀️☀️☀️& Sunset🌅🌅🌅.
      What's WHO'S Means
      World happiness organization(Along 100 years back Making happiness to all world all is always well with lovely enjoying with 🌿🍃🌿🍃 &🌕🌕🌕🌕). That time old is gold.
      ( or)
      World Health Organization ( Making money from pharma companies , technology companies & spoiled all life) . This time
      New world is going to worst situation.
      Now I am remembering one poem to all world.
      Poem
      Old is gold & New is worst,
      The all world is going to worst situation,
      Little be sea a All Nature to ours,
      Fanally at what time all of them Near to nature & love to Nature🌲🌳🌴🌲🌳🌴🌲🌳🌴🌲🌳🌴🌲🌳🌴🌲 🌳🌴&Sunlight☀️☀️☀️☀️ Definitely all is always well with lovely enjoying.
      Otherwise 200 Persent the world is going to worst conditions including coming kids.
      One more think now I am remembering to all🌍🌍🌍🌍 & lovely enjoying with Sunlight 🌕🌕🌕🌕🌕 & Nature🌿🍃🌿🍃🌿🍃🌲🌳🌴🌲🌳🌴🌲🌳🌴🌲🌳🌴🌲🌳🌴🌲🌳
      All of them Daily will Spend lovely enjoying with Nature🌿🍃 & Sunlight🌕🌕🌕.
      ( How much time :As per depends surrounding all our area's) .
      Never hurt Nature...🙏🌍😢
      ....Trees are costless
      Nature Doesn't need People....People need Nature. 🌍🌳🙏
      Please Plant trees plant hope 🌳❤🌳
      Plant Trees 🌳🌍🌳.
      All of them one thought will Save our Brain .
      What is one thought means Any one suffering from Any health Problem from our side in that time all of us will feel that's ( Any health issue or Corona) a my best friend.
      At what time Now a days all of them will save these type of thought Definitely all is always well with lovely enjoyment & entiretinement with Nature🌿🍃& Sunlight🌕🌕🌕.
      If anything anywhere wrongly mentioned in my all matter please share along with solution. That's my crores of happiness.
      Mobile number:08142040339.

  • @ChemEDan
    @ChemEDan Před 2 lety +7

    11:32 Never happens in a vacuum - right after mentioning Apollo 🌙

  • @sharonkende4774
    @sharonkende4774 Před 2 lety +1

    For the first half of the video, it sounded like Hank was saying that all you must do is "download" the mRna into your body. Then in the second half, he got into detail but I almost did not wait until then because I was thinking he would gloss over the details. He didn't and delivered an amazing video. I think that this is so informative and helpful. thanks

  • @SkyRotionDan
    @SkyRotionDan Před 2 lety

    this is soooo much science and history goin on in 1 video