**Correction*** Hey Ninja Nerds!! The laryngeal cartilages are actually derived from the 4th and 6th pharyngeal arches NOT the 1st!!! Sorry about that ninja Nerds!!! Hope this video is helpful! Love you ninja Nerds!!!
Hey man can you tell me something I'm a bit confused about it Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
Hey man can you tell me something I'm a bit confused about it Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
Development of limbs 1.HOX, TBX4 & TBX5 genes determine the position of formation of limb buds. Once activated, they stimulate release of FGF-10 (fibroblast growth factor). Ectoderm grows off as 4 limb buds. Somatic layer of lateral plate mesoderm moves into limb buds. FBG-10 stimulates a thickening at the tip of the limb buds called apical ectodermal ridge (AER). AER secretes FGF-4 & FGF-8 which causes proliferation of somatic mesoderm. the most distal part keeps proliferating (progress zone) while the proximal part of limb bud starts to differentiate. From cartilage to bone (endochonrdal). Some tissue in AER undergoes apoptosis due to bone morphogenic protein (BMP) & retinoic acid increase. Starts to form fingers. Mesoderm starts to proliferate to make finger bones. AER dies off to stop growth. Tissue called zone of polarizing activity (ZPA) develops on posterior disal limb which causes the asymmetrical growth of the hand. Thumb to pinky.
Hello Zack, I’m a medical student from Iraq, and I just want to thank you for all the work and time you’ve given for everyone who watches your videos. You explain in a such way that is comprehensive yet still fun and enjoyable. Keep going man, wish you the best of luck!
when my med school prof lectures about this subject she just throws it all up on one powerpoint slides and talks through the whole thing at once, which i find very hard to follow and understand. drawing it out step by step like this is immensely helpful, thanks!
I just wanted to say a most sincere THANK YOU! I really appreciate your work and you must know how much it helps everyone who wants to learn. Thank you again ♡
Hi Zach. I am Alice, a Nursing Student from Nigeria. I love your energy and enthusiasm while teaching. You also made this topic easier for me. Thank you.
Hey man can you tell me something I'm a bit confused about it Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
Brilliant as usual. But what i really want to thank you for is your positive energy. I woke up not in the mood for learning anything about embryology 😂. But the way you explain and the way you seemed so excited is so refreshing! And contagious. So again, thankyouu for making our lives easier
Hey man can you tell me something I'm a bit confused about it Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
Hey man can you tell me something I'm a bit confused about it Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
Thanks ninja nerd, i am a second year medical studen from venezuela, your videos are super easy to understand and it have being keeping me motivated trhough quarantine. I am even thinking about opening my own youtube channel now. thanks
Hey man can you tell me something I'm a bit confused about it Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
Hey man can you tell me something I'm a bit confused about it Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
Hey man can you tell me something I'm a bit confused about it Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
During the first half of the video I was trying to figure out what kind of drug Zach is on. Then I realised it's just embryology. Because damn, embryology is so so cool!!
I just got my psychotic preworkout in the mail! Omg!!! I feel the electrons coming out of my membranous neurocranium!!! Thank you Zach!!!! Biochemistry major let’s do this then MCAT!!
Hi ZACH . I am an Electrical Engineering Student But I'm here to Subscribe you channel because My Brother loves Your Lectures. Keep up the great work! LOVE From PAKISTAN..............
Its 3:00 am, i have an end of sem 1 exam and things just escalated quickly from neuroanatomy to embryology to bchem...am glad this made my work 1000 times easier
Zach, After watching many Ninja Nerd Lectures on CZcams, I've become very impressed with your knowledge. Are you accepting patient? If so, how would someone become a patient of yours?
Hello guys !!!! Omgggg thanks for amazing videos really !!! I swear when ever Zach says " oh man it's so cool " or " isn't that cool ?" I keep rewatching that part 😍😍😍and I swear I learn a lot better he knows how to drag good attention to super important parts !!! And yet keep it so intresting ! Like only by his joy in his face he converts all boaring materials into such a cool one to learn ! Thank you guys ! May God always bless you and get your backs !!! I love youuuuu guys
Hey man can you tell me something I'm a bit confused about it Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
from ninja to nerd and where I'm at? I'm dead in the water mate, and it ain't a pretty sight! But thank you for all the work you've done and are still doing.
**Correction*** Hey Ninja Nerds!! The laryngeal cartilages are actually derived from the 4th and 6th pharyngeal arches NOT the 1st!!! Sorry about that ninja Nerds!!! Hope this video is helpful! Love you ninja Nerds!!!
Hey, sorry I think the part where you explained the process of differentiation of fingers got deleted or skipped? Thank you!
I was going to correct this. Good job
Tnx
hyoid bone actually derives from second as you said in pharyngeal apparatus video
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I love it when Zach says things like, "isn't that cool?!" I swear having an excited, passionate teacher makes SUCH a difference. Thanks, Zach!
2:55 he even says "neural crest cells" as if he just met the love of his life for the first time AHHAHA great lecturer!!
Hey man can you tell me something I'm a bit confused about it
Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
A Pakistani Med student here, learning a lot from your videos. Keep up the good work
A Pakistani med student here, trying to study embryology from scratch 2 days prior to the exam. Thank you for your energy and explanation!
Same here , used to overestimate it, but it’s such an exciting subject, kudos to Zach sir
Zach you are my mentor and hero. You don't even take Sundays Off! Thank you so much. God Bless you and everyone
We are always in your corner! No days off! 🤓
Hey man can you tell me something I'm a bit confused about it
Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
Development of limbs
1.HOX, TBX4 & TBX5 genes determine the position of formation of limb buds. Once activated, they stimulate release of FGF-10 (fibroblast growth factor).
Ectoderm grows off as 4 limb buds. Somatic layer of lateral plate mesoderm moves into limb buds. FBG-10 stimulates a thickening at the tip of the limb buds called apical ectodermal ridge (AER).
AER secretes FGF-4 & FGF-8 which causes proliferation of somatic mesoderm. the most distal part keeps proliferating (progress zone) while the proximal part of limb bud starts to differentiate. From cartilage to bone (endochonrdal).
Some tissue in AER undergoes apoptosis due to bone morphogenic protein (BMP) & retinoic acid increase. Starts to form fingers. Mesoderm starts to proliferate to make finger bones. AER dies off to stop growth.
Tissue called zone of polarizing activity (ZPA) develops on posterior disal limb which causes the asymmetrical growth of the hand. Thumb to pinky.
sincerely, thank you for this. you have made my exam period at least an hour or two shorter.
Hello Zack, I’m a medical student from Iraq, and I just want to thank you for all the work and time you’ve given for everyone who watches your videos.
You explain in a such way that is comprehensive yet still fun and enjoyable.
Keep going man, wish you the best of luck!
Which book do he follow?
يييي بالقرآن
يامرحله ضلعي ويا كليه
@@Shinzo9567 طب تكريت مرحلة ثانية و انت؟
@@TheMoonlight258 اني هم مرحله ثانبة مستنصريه
when my med school prof lectures about this subject she just throws it all up on one powerpoint slides and talks through the whole thing at once, which i find very hard to follow and understand. drawing it out step by step like this is immensely helpful, thanks!
I just wanted to say a most sincere THANK YOU! I really appreciate your work and you must know how much it helps everyone who wants to learn. Thank you again ♡
i'm an Italian med student and I actually prefer this to may Professors. Thank you for everything you make Zack and crew
I am an Iraqi med student. Definitely, it’s better than what the professors give. It’s well organized and simply explained and understandable
Am a proud Ninjanerdian 🎉. Thanks buddy 👍
Hi Zach. I am Alice, a Nursing Student from Nigeria. I love your energy and enthusiasm while teaching.
You also made this topic easier for me.
Thank you.
I am very grateful for the support you are giving us ninja nerds you are the most influential man in my medicine career
Thank you so much for providing all these lectures!!! 💕 looking forward to more embryology lectures from you!
Hey man can you tell me something I'm a bit confused about it
Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
I can't stress enough how you actually saved my medschool life 😭
Those with ADHD but still fighting, i feel u and im proud of u guys we can be even better …
Thank you!
You are SIMPLY THE BEST ZACH!!! thank you thank you for all your hard work and dedication!
Brilliant as usual. But what i really want to thank you for is your positive energy. I woke up not in the mood for learning anything about embryology 😂. But the way you explain and the way you seemed so excited is so refreshing! And contagious.
So again, thankyouu for making our lives easier
Hey man can you tell me something I'm a bit confused about it
Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
Embryology😻 The greatest gift ever for my upcoming semester. Thank You Mr👍🏻👍🏻👍🏻👍🏻
In love with his way of teaching 😭❤
Zach is a treasure that must be preserved!
Nerdology : Development of Ninja Nerds
😂😂
That would be the study of ninja nerds. The development would be called Nerdogenesis. 😉
It is amazing how you are able to make these wonderful educational lectures! I am Rachel from NL and I really love them!
Having histo+ embryo in two days and this just came perfectly in time!! THanks!
Wow! Excellent explanation!
Thank you so so much for putting the time and the effort to make these topics very enjoyable to learn.
Your passion really gives it more color and makes it interesting.. very inspiring
thank you
Never have I ever wanted to hit the like button so many times. Thank you so much!
Ayyyyy, let's go! Missed embryo lectures
I've been waiting for a long time for this! Thanks a lot!
Lucky to have you as my teacher thanks sir for all the beautiful informative videos
omg! finally it all comes together making sense! I am so thankfull for your job and for the fact i had the luck finding you
I'm not even learning this yet but I just wanted to comment to voice my support for this channel. Just incredible
Your videos are as good as it can get.thankyou so much and please keep them free on youtube
Thank you for breaking down such difficult topics!!!
This video published less than 48 hours before embryology exam. Nothing less of amazing. Thank you guys!
Hey man can you tell me something I'm a bit confused about it
Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
I'm in love with this channel, thank you so much
Love this. Ur passion really gives me the motivation to learn!
Thank you prof Zach..You jus the best ...You make our med school life easy
great video~ currently an MD1 and this has helped alot!
Thanks ninja nerd, i am a second year medical studen from venezuela, your videos are super easy to understand and it have being keeping me motivated trhough quarantine. I am even thinking about opening my own youtube channel now. thanks
Hey man can you tell me something I'm a bit confused about it
Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
Finally, embrio vids, really needed these to jog the memory
I always hated embryology!! until I found your videos :)) it can be sooo interesting! THANK YOU 😀
Thank you, thank you, thank you!
Keep it up with embriology!
Hey man can you tell me something I'm a bit confused about it
Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
I can see how much effort you made when I see your videos
brilliant teaching from you Zach...you're a blessing to us!
Hey man can you tell me something I'm a bit confused about it
Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
this guy hits it everytime! thank you brother
During the first half of the video I was trying to figure out what kind of drug Zach is on. Then I realised it's just embryology. Because damn, embryology is so so cool!!
Thank you Zach so understandable and simplified
Lots of love from Medical School of the University of The Gambia🇬🇲🇬🇲🇬🇲🇬🇲🇬🇲🇬🇲Thank you so much for your videos.. you're just Amazing!
I just wanna say thank you very much and keep going in making wonderful videos
You have no idea how easy you’ve made me revision process for exams
Thank you very much 💚. We are waiting for the embryonic formation of the cardiovascular system
Dear Zach Thank you for this! Explanation for the 44:40 is missing about Retinoic Acid and SHH about how Gremlin-1 is released
Thanks you sir. Really helpful.. forever a proud ninjanerd
youre the best thanking you for helping me through medical school
thank u soo much for this video, it's helping me to understand more during my uni class
really appreciate your work , thank you .
Man you are literally my career saviour ❤️
I just got my psychotic preworkout in the mail! Omg!!! I feel the electrons coming out of my membranous neurocranium!!! Thank you Zach!!!! Biochemistry major let’s do this then MCAT!!
Now this guy is just exceptional
Nice to see, how much fun you have with this stuff
bro has rocked my world
Hi ZACH . I am an Electrical Engineering Student But I'm here to Subscribe you channel because My Brother loves Your Lectures. Keep up the great work!
LOVE From PAKISTAN..............
Its 3:00 am, i have an end of sem 1 exam and things just escalated quickly from neuroanatomy to embryology to bchem...am glad this made my work 1000 times easier
Thanks for your efforts Ninja crew
Thank you very much zach. This is really top notch
Zach,
After watching many Ninja Nerd Lectures
on CZcams, I've become very impressed with your knowledge. Are you accepting patient? If so, how would someone become a patient of yours?
Hello guys !!!! Omgggg thanks for amazing videos really !!! I swear when ever Zach says " oh man it's so cool " or " isn't that cool ?" I keep rewatching that part 😍😍😍and I swear I learn a lot better he knows how to drag good attention to super important parts !!! And yet keep it so intresting ! Like only by his joy in his face he converts all boaring materials into such a cool one to learn ! Thank you guys ! May God always bless you and get your backs !!! I love youuuuu guys
Hey man can you tell me something I'm a bit confused about it
Is it Thyroid hormone or estrogen which triggers endochondral ossification of epiphyseal cartilage in the long bones during puberty?
Omg... Perfect timing! ❤️❤️❤️
I thought you went bold in first few seconds because of the hat lol 😂
I thought his head is distorted and I wad like wtf until I read your comment lol
Greatest teacher ever ❤
Love ur dedication zack🖤🖤
I swear I have NEVER even considered signing up for Patreon for any other channel except this one. I hope I will in the future.
Wow ...thank you ...your all videos are interesting...you make me love 😘 the medicine...
Thank youu soo muchh ninja nerd u make things soo much clear
Thank you Ninja Nerd.
You make the madicine so easy 🔥🔥🔥love you
Watching your videos from somalia 🇸🇴 and thank you for sharing these wonderful videos with us (med students)
The way you talk to the audience looks so enjoyable that really attracts us by your lectures.
Love your spirit ❤️ Keep it up 👍
thank you so much for such an effort and explanation
I had to stop this video and appreciate this guy 👏
Bless y’all 💕
The lecture is so nice, understandable and interesting,,add more for us!!!!
Holy smokes! 1000 Likes and 0 dislike! Zach you are amazing!
Always wait for your videos
Thank You , Sir
The greatest ever
Dude without you my medical journey is sh*ty♥️
Awesome lecture.
This man is Good
always helpful thank you mr
Life saving video .. zach❤
perfect
thank you very much❤️❤️👌
from ninja to nerd and where I'm at? I'm dead in the water mate, and it ain't a pretty sight! But thank you for all the work you've done and are still doing.
As always Amazing ❤👌
Worderful piece of work
Thanks dude this was great.
Best instructor ever 🫀
you are a great teacher sir
Really sir i have no words to explain how you are helping us by your great lectures......amazing sir
Was about to study this topic😍
you are the best ,thank you so much