Googles ALPHAFOLD-3 Just Changed EVERYTHING! (AlphaFold 3 Explained)

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  • čas přidán 7. 05. 2024
  • Googles ALPHAFOLD-3 Just Changed EVERYTHING! (AlphaFold 3 Explained)
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    Paper: www.nature.com/articles/s4158...
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Komentáře • 122

  • @doingtime20
    @doingtime20 Před měsícem +68

    Alphafold and its contribution is highly underrated, I don't think people understand how many medical advances we will see in the coming years.

    • @Mimi_Sim
      @Mimi_Sim Před měsícem +9

      My old prof must be crapping his pants - protein structure prediction was his field of research. This is incredible. All of the “Alpha Folds” are.

    • @DailyTuna
      @DailyTuna Před měsícem +4

      A lot of it will be to counter the environmental medical consequences of our lifestyle . people are more unhealthy now than they’ve ever been in history due to these factors. Gotta keep the annuity going for the big.

    • @strictnonconformist7369
      @strictnonconformist7369 Před 29 dny +5

      It'll also be far more efficient to create bioweapons more efficiently than ever before, too...

    • @labmaier3426
      @labmaier3426 Před 29 dny +2

      I agree

    • @unityman3133
      @unityman3133 Před 29 dny

      @@strictnonconformist7369 it can also create cures for those bioweapons.....

  • @vaendryl
    @vaendryl Před měsícem +23

    the importance of this can not be overstated.
    if we're ever going to truly cure cancer (or at least, most cancers), tools like these will be absolutely instrumental.
    and that's just a single example of how big of a deal this is.

    • @shaoouhai3532
      @shaoouhai3532 Před 28 dny +2

      The importance of this can not be overstated.

    • @vaendryl
      @vaendryl Před 28 dny

      @@shaoouhai3532 that. you is right.

  • @Lugmillord
    @Lugmillord Před měsícem +26

    This will be huge for medicine! Hopefully a cure for my illness will be possible in a couple of years.

    • @_rd_kocaman
      @_rd_kocaman Před 29 dny +8

      you understand how valuable health is when you lose it. wishing you healthy life, your cure might even come earlier than you expect!

    • @christopherarendt3531
      @christopherarendt3531 Před 29 dny +4

      Same, best of luck to us all, I'm wishing all the best for advances in AI.

    • @squamish4244
      @squamish4244 Před 24 dny

      I have chronic illness too. For 30 years. It stole my youth and my dreams.
      One of my favourite quotes is: "A healthy man wants a thousand things, a sick man has but one."

    • @IAMDEMIURGE
      @IAMDEMIURGE Před 16 dny

      ​@@squamish4244 stay strong bro you will make it

  • @danellis-jones1591
    @danellis-jones1591 Před 29 dny +5

    This, coupled with the big jump on compute power of the new Blackwell Nvidia AI GPU could seriously change medicine in a matter of a few years.
    Already stage 3 trials are being started on individualised immune therapy that's showing great signs for curing cancers. But this new Alphafold is unbelievable. Hard to not get too excited about it.

  • @Thechatwithchad
    @Thechatwithchad Před měsícem +19

    Singularity nears

    • @gregmasseyify
      @gregmasseyify Před měsícem +3

      Say it loud brother!

    • @gregmasseyify
      @gregmasseyify Před měsícem +3

      I this it's fair to say this is genuinely shocking and surprising. This has incredible consequences

    • @LilBipper
      @LilBipper Před 29 dny +1

      Literally just said this to my wife 😅😊

    • @honkytonk4465
      @honkytonk4465 Před 29 dny +1

      Lock your doors

    • @g.orbeliani.1
      @g.orbeliani.1 Před 29 dny +1

      how do you actually see the earth and human life in general, when you say the singularity?

  • @bradshelton2397
    @bradshelton2397 Před 29 dny +7

    This is the AI I was truly waiting for I wanted to see what was next by this thing ever since the first amazing breakthroughs

  • @andycampano
    @andycampano Před 29 dny +3

    I keep saying that in the next couple decades we're going to solve all the most fundamental human problems. All of them.

  • @armadasinterceptor2955
    @armadasinterceptor2955 Před 29 dny +9

    Everything is falling in place.

  • @feel-love
    @feel-love Před měsícem +7

    One small step for man one gaint leap for mankind 😮

  • @PeopleAdverts
    @PeopleAdverts Před 23 dny +1

    Whenever they talk about Ai destroying the world they should balance it with this. Amazing

  • @labmaier3426
    @labmaier3426 Před 29 dny +2

    The really cool thing is that they can predict how they‘ll will interact.

  • @squamish4244
    @squamish4244 Před 24 dny +1

    "A healthy man wants a thousand things, a sick man only one."

  • @proximal1846
    @proximal1846 Před měsícem +11

    I wonder what breakthroughs we will see.

  • @steve-real
    @steve-real Před 29 dny +1

    The rate of change over the last decade is stunning

  • @Paul1239193
    @Paul1239193 Před 29 dny +8

    Any guesses for how long until they solve aging?

    • @ooberholzer
      @ooberholzer Před 29 dny +1

      3 years

    • @HanzDavid96
      @HanzDavid96 Před 29 dny +3

      For solving aging you may need to understand almost all processes in the human body almost perfectly.
      - First AGI between 2025 and 2028
      - First ASI between 2026 and 2031
      - Understanding the most processes in the human body very well: ASI + (1 to 8 years)
      - Medic prototyping (+1 to 3 years)
      - Testing (+10 years)
      - Availability (+3 years)
      So iam guessing that aging will be solved between 2028 and 2042
      Also iam guessing that the therapy will be available between 2041 and 2055

    • @vaendryl
      @vaendryl Před 28 dny +1

      Curing cancer would be much easier...
      At least 50 years. And that's assuming the singularity is now upon us.

    • @PeopleAdverts
      @PeopleAdverts Před 23 dny

      There is over 500 well funded start ups using Ai to combat aging and immortality.

    • @okthatsnice
      @okthatsnice Před 17 dny +1

      Probably the same amount of time it takes us to reach ASI, if we do that soon / we let it recursively self improve quickly.

  • @DuderMcDudenstein
    @DuderMcDudenstein Před 10 dny +1

    What is the name of the beautiful discovery music that begins at 10:48?

  • @lynntatro7374
    @lynntatro7374 Před 29 dny +2

    Amazing!

  • @MissTryALot
    @MissTryALot Před 7 hodinami

    If I take a wrong turn just have my funeral please

  • @deep9th
    @deep9th Před 29 dny +1

    It's interesting how folks are prone to talk only about the positive aspects of something. Like we're living in a perfect world and only good can come out of it. Does anyone think about what kind of power it gives to pharmacy? How easily they can make us, not dead (no money there), but chronically ill. I guess big pharma already celebrating

  • @danielpetersen6791
    @danielpetersen6791 Před měsícem +4

    Really really pretty pretty crayzeee

  • @FullOfFallaciesVideo
    @FullOfFallaciesVideo Před 7 dny

    Does anyone know if AlphaFold 3 could be useful in any way for fighting against Prions, which are misfolded proteins which lack DNA, are infectious, and cause healthy DNA to misfold as well...
    They are the cause of animal CWD (Chronic Wasting Disease), which targets primarily deer, and has not yet made the jump to humans (that we know of -- it is a HORRIBLE way to go)...
    It was also heavily implied that it is also a direction to take toward seeking a cure for Alzheimers Disease...

  • @taomaster2486
    @taomaster2486 Před měsícem +3

    Simulating all proteins would be pretty cool for simulations

  • @schuylerhaussmann6877
    @schuylerhaussmann6877 Před 29 dny

    I'm shocked!

  • @carlharrison3637
    @carlharrison3637 Před 29 dny +1

    So AI will be able to come up with the best way to delete us all then. Good to know.

  • @blengi
    @blengi Před 29 dny +1

    I'm surprised they haven't found testable pathways for abiogenesis yet

  • @deepesholi4576
    @deepesholi4576 Před 28 dny +1

    'Playing god' is near.

  • @litbmeinnick
    @litbmeinnick Před 24 dny +1

    I was born 40 years too early 🤪

  • @ogr3dblade6
    @ogr3dblade6 Před 29 dny +1

    ok cool i am defo gonna freeze myself and be revived by AI in 200 years

  • @AndrzejLondyn
    @AndrzejLondyn Před měsícem +2

    AI, smart drugs but me and my wife are both disabled wheelchair-bound. We live in East London Newham United Kingdom.
    We don't have any medical or social care or even a half incontinence pant.

    • @PowWowDAO
      @PowWowDAO Před měsícem +1

      Jesus loves you and offers you eternal life

    • @TiagoTiagoT
      @TiagoTiagoT Před měsícem +2

      I don't have experience in this area, but there must be some online communities that the very least offer emotion support for people in your kind of situation, but possibly even useful advice or even more tangible forms of assistance.

    • @brianmi40
      @brianmi40 Před 29 dny +1

      How do you not have the NHS in the UK?

    • @honkytonk4465
      @honkytonk4465 Před 29 dny +1

      No support from the best invention since sliced bread,the NHS ?

    • @ooberholzer
      @ooberholzer Před 29 dny

      Try to farm cryptocurrencies... the system is dying, be ready for the next one... instruct yourself on the subject starting today. be careful, 99% of the things you'll read are scams, find the truth and communicate with people you trust on the subject. start now

  • @TeamLorie
    @TeamLorie Před měsícem +2

    I don't have any funky molecules.. 😅

  • @shadyshiba9834
    @shadyshiba9834 Před 29 dny +1

    Oh great isnt protein folding the thing that will turn us all into paper clips or grey goo?

  • @d1didit799
    @d1didit799 Před měsícem +7

    I watch your videos on 2x speed

    • @Legorreta.M.D
      @Legorreta.M.D Před 29 dny +3

      Thank you for your contribution. In other interesting news, I’m wearing socks 🧦

  • @user-td4pf6rr2t
    @user-td4pf6rr2t Před 29 dny

    so this will explain like quantum entanglement and higgs boson? This perhaps is beyond my scope specifically but i appreciate someone applying generative to something other an devops hardening. Of the evolving technology...
    7:35 But this would only be true if they have the data from the generative process that scales years into days, or am I miss understanding how FDA guidelines work(either this or ai safety is pulling more wool over end-user eyes for funding in search of its own tail?) right?
    9:22 Very cool but this is starting to sound more like just using big words and mentioning key-terms that resonance with what people want to hear without actually addressing any of the real world obstacles in a real life setting. Even which if true the target campaign is going in the right niche but how come ai safety needs to be so evil and actually hurt the areas of study instead of accelerate it like AI is imagined for?
    I don't get it...

  • @MichaelErnest666
    @MichaelErnest666 Před 29 dny +1

    1010

  • @ismaelplaca244
    @ismaelplaca244 Před měsícem +37

    Changes everything? I want to see what it really changes.

    • @BryanWhys
      @BryanWhys Před měsícem +17

      Lol how do you not understand the implications of this?

    • @jenovas00
      @jenovas00 Před měsícem +26

      It already is changing everything. They discovered thousands of new materials and possible superconductors. You already have labs around the world trying to build some of these materials, I think we have like 700 different new materials already created and are being tested. Before companies spent months / years creating a new material to test, now they have a list of 2mln non-existing materials found by stuff like Gnome and they go through that list and build stuff they think might work. This is still a long process but instead of creating 5 new materials per year that we test and often throw out all of them cause they are fails, we can create now 700, and even if they all are fails the chance of finding something that will actually work is 100x higher than just a few years ago.

    • @jenovas00
      @jenovas00 Před měsícem +6

      Look at it like the record sniper shot is 4km.
      Before having this technology we were a blind guy with a pistol trying to hit a target 5km away from us not knowing in what direction the target is.
      We could fire hundreds of thousands of shots and never hit, never even be close to hitting.
      Now we actually found a sniper rifle and know in what direction to look, hitting a target 5km away is still an unbelievable thing that will take thousands of shots maybe hundred of thousands, but eventually with a bit of luck you should land one hit.
      With a pistol even after a mln shots you probably still wouldn't be anywhere close to the target.
      So we still gotta do the incredible world breaking shot and shot thousands of bullets to maybe get one, but at least now we got the proper tools to try to even do the shot and we actually know in what direction to shoot.

    • @DailyTuna
      @DailyTuna Před měsícem +3

      More mRNA vaccines for you and me 😂

    • @CaseySolvberg
      @CaseySolvberg Před měsícem

      it will transform our understanding of drug discovery

  • @chadwalker9804
    @chadwalker9804 Před měsícem +3

    The progress that Alphafold has made over the last few years is truly breathtaking, but I feel like we aren't seeing the forrest through the trees. As exciting as it is to think about all of the diseases we are going to be able to cure in the short term, it doesn't seem like anyone is discussing the long term impacts on population. By circumventing the spread of disease on such a large scale, we are messing with a system that has seen life propagate successfully on earth for roughly 3.7 billion years. I feel like the short term gains are going to pale in comparison to the suffering and hardships caused over time. On average, 50 million people die from disease each year worldwide. Many of those in developing nations. Let's say we are able to eradicate half of those deaths, not to mention the potential to increase average life expectancies and fertility rates. It's not hard to see the potential for massive societal collapse due to an explosive population surge.

    • @pyonchan1804
      @pyonchan1804 Před 29 dny +1

      so someone like me with a fatal genetic disorder should just go to hell?

    • @strictnonconformist7369
      @strictnonconformist7369 Před 29 dny +2

      A point many have not recognized yet is as the standard of living goes up, the population growth goes down.
      South Korea is well below replacement rate now. If not for all the illegal migrants the US would be falling for population already.

    • @maxbaugh9372
      @maxbaugh9372 Před 29 dny

      @@strictnonconformist7369 For all the press they get, illegal immigrants are not the reason the US population is growing, even if there were zero illegal immigrants the US population would still be growing.

    • @chadwalker9804
      @chadwalker9804 Před 29 dny

      @CdawgAMVsFilmEditing "The responsibility will be on us to not replicate like a virus." Hence my concern.

    • @chadwalker9804
      @chadwalker9804 Před 29 dny

      @@pyonchan1804 Not at all. I hope you and others like you benefit from the advancements that are on the horizon. I actually suffer from a nerve disorder called CRPS, also known as "the suicide disease". I have been waiting 23 years for an effective cure, but I try not to by short sided about things simply because they benefit me. I'm not saying that's what you are doing, It's simply something that I don't see many people having honest discussions about. There have been unforeseen consequences with just about every technological advancement we've made and Alphafold is set to be an exponential leap forward into uncharted territory.

  • @lisizecha9759
    @lisizecha9759 Před 29 dny

    These are millions of highly qualified jobs being eliminated before our eyes
    Keep in mind, that the work product is still available, so it is now a question of distributing the proceeds
    Give it all to a few billionaires is one option

  • @SeanOHanlon
    @SeanOHanlon Před 29 dny +1

    😳

  • @angloland4539
    @angloland4539 Před 29 dny

  • @T1tusCr0w
    @T1tusCr0w Před měsícem +4

    I wonder if it’s good to have this kind of information on us and everything else.. 🤔

    • @ZenTheMC
      @ZenTheMC Před měsícem +6

      If you want the cures to diseases, human augmentation, etc., this is a trade-off you'll need to make peace with. I’ll take the science and tech that could bring me to the future, personally.

    • @justinwescott8125
      @justinwescott8125 Před měsícem +4

      Well phrase it this way and then decide. "I wonder if humans deserve to know how their bodies work?"

    • @T1tusCr0w
      @T1tusCr0w Před měsícem

      @@justinwescott8125 I’ll phrase it better - I wonder how comfortable we are with trillion dollar corporations being the arbiters of the well of eternal life? 🤷🏻‍♂️

    • @BryanWhys
      @BryanWhys Před měsícem +2

      If you have a molecular map of yourself at any given ti.e you can know exactly what to do to compensate for bodily malfunctions

  • @alertbri
    @alertbri Před měsícem +6

    Craaaaaayyyzzzzeeeeee

  • @kevinsm2039
    @kevinsm2039 Před 29 dny

    Now we gotta be cautious with all these “breakthoughs” it could just be some ploy to get their stock prices up.

    • @brianmi40
      @brianmi40 Před 29 dny +3

      We should be so lucky to have companies offer such FREE TOOLS in an attempt to "raise their stock price" as a "ploy".

    • @kevinsm2039
      @kevinsm2039 Před 29 dny

      @@brianmi40 maybe you don’t value your money at all, but I certainly don’t want companies overpromising or over hyping any new features so they could pump their own stock and eventually sell.

    • @kevinsm2039
      @kevinsm2039 Před 29 dny

      @@brianmi40reminds me of when Elon fan boys crossed their hearts to die that Elon musk would get to mars by 2024 and invest heavy in Tesla 🤣🤣 Just so Elon could cash out and leave the fans boys broke

    • @brianmi40
      @brianmi40 Před 29 dny

      @@kevinsm2039 LOL, you think GOOGLE is "cashing out" due to a FREE TOOL.
      genius.

  • @DraaelD
    @DraaelD Před měsícem

    Bro stop. Every other video from you “changes something”. God. Enough with the baiting.

    • @thymenwestrum7011
      @thymenwestrum7011 Před 29 dny +8

      But it is literally crazy, how are you this decentized

    • @Legorreta.M.D
      @Legorreta.M.D Před 29 dny +7

      @@thymenwestrum7011 DræeeellddDdd doesn’t understand the first thing about medicine

  • @CHIEF_420
    @CHIEF_420 Před 29 dny

    @Google
    🤖 (con Gemini)