Uğur Şahin and Özlem Türeci: Meet the scientist couple driving an mRNA vaccine revolution | TED
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- čas přidán 24. 05. 2024
- As COVID-19 spread, BioNTech cofounders Uğur Şahin and Özlem Türeci had one goal: to make a safe, effective vaccine faster than ever before. In this illuminating conversation with head of TED Chris Anderson, the immunologists (and married couple) share the fascinating story of how their decades of mRNA research powered the Pfizer-BioNTech vaccine -- and forecast what this breakthrough science could mean for the future of vaccines and other immunotherapy treatments.
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Herşey için teşekkürler Uğur bey ve Özlem hanım...♥️♥️
LOL
Yağcı!
@@user-lo5uh5su5l ne yağcısı para mı verecek milyonlarca insanın hayatını kurtaracak aşı geliştirmiş teşekkür ediyor ne yağcısı niye öyle dedin
@@CengizNoker kendisi aşı olmadı yağcılar.
@@user-lo5uh5su5l Bu iddialara Uğur Şahin aşı olduğu resmi paylaşarak cevap verdi biraz araştırabilirsen bulabilirsin
Such an inspiring couple, humble and dedicated scientists! The world appreciates what you did and will never forget forever. What inspired me the most is that they started working on the vaccine right after they heard a new virus arising in China, before it spreads to the World, and before we know about aggressiveness and clinical significance. As a scientist, they have all the qualities including foresight. Proud as a Turkish doctor who is trying to be a physician-scientist in the future.
The real developer of the bases of the Covid vaccine were KATALIN KARIKO Drew Weissman. Kariko is the weispresident of Biontech
LOL
🤡
Lol, did u check this company history
@Helin biliş Kurdish to be precise
They both remind me of Marie and Pierre Curie.
The remind me of Fred and Rose West
As in they were personal friends of you ? 🧐
No.
I thought the same! Some of those rare people who change the world. Incredible
@@derlichtbringer6355 indeed they did, but as politicians, not scientists. Name a few scientists who changed the world, either good or bad?
Impressive, they didn’t have one single approved product in the pipeline, and suddenly within 11 months they produce gen-therapy shots which the entire humanity is coerced into. If this is not scary, what is???
@@mayatara1980 🤣😂🤣😂😂
Very surprising. But that's what Sabateans do
Facts ?
*Teşekkürler - Thank you*
makes me proud to be human when I see people like these two. Such humility, such kindness of their souls, such passion for their work. Thank you drs.. We owe you our lives.
These two precious people deserve all the kindness in the world.
Do some research, you should get out of the bubble that you live in
what for, really?
They seem so kind and driven by desire to help. So inspiring, thanks!
O yes and they are so uninterested in the money...pfizer ist the most expensive vaccine and the price has been increased...
@@catherinelechevalier2015 they don’t work for Pfizer though, but for BioNtech. And Moderna is the most expensive covid vaccine!
Keep on dreaming!
I mean they became richer than God so that was quite motivating too so
@@joeygio9586 werent they the two who found the company biontech
We have a good reason for hoping a better world. Two dedicated,inspiring, humble scientists ,they deserve all the best of all good wishes. I thank them.
A great Muslim couple with a grand vision to do good in the world.
Two amazing people!! 🇹🇷❤️🇹🇷❤️🧿🧿
🇩🇪❤️🇩🇪❤️🌭🍺
@@mahmut123456 Wow, this is ethnic discrimination. Do you have a problem with these scientists' ethnic bacgrounds? Or are you just turkophobic?
You should read that why they forced to relocate. May be you’ll shame that you put turkey flag
@@gezenbilir8438 No, I will never ever shame of Turkish flag! I’m always proud of my flag! Bad governments cannot put me off from my flag. It’s not their flag, it’s our flag! No one can change the fact that they are Turkish Germans, this is all I care as a Turkish British and I always be proud of these couple forever, who rule the world and there is nothing wrong with this! This should be a Turkish common sense! 🇹🇷❤️🧿
@@gulbaykan3840 Move Turkey if you love so much.
Very inspiring. They are so great. Thanks to Biontech, Ugur Sahin, Özlem
Türeci for saving so many lives, for being prepared for reacting in the right manner. Must have been very very very difficult for you and your team.
😂😂😂
I don't under mine the sports, movie and celebrities who are making millions to hundreds of million dollars like KIM KARDASHIAN her her gang, Kanye West, Madonna, Tom Brady and others but Dr. Sahin and Dr. Tureci people like them who works so hard serve the HUMANITY.
Our TEACHERS, ACADEMICS, SCIENTISTS should DESERVE the MOST RESPECT!
Thank you.
for what?
Legends and such humble people
Fk ur legends , this are murderers
@@truestrength-oz5kk shut up mann shut upp!!
The last sentences addressing their nationality was brilliant! 🧿 P.S. They're such a sweet couple!
Globalization has pros and cons
Linguistically they are clearly German through and through, especially Dr. Sahin who has a strong German accent (which I find charming).
@@monikaherr3562 they are from turkey. but they live and work in germany.
@@monikaherr3562 As stated by Mesut Ozil, "when I play well, I'm German, when I play bad, I'm an immigrant". But yes, strictly linguistically, they're very German.
I am so happy that the german education system is able to bring up such great researchers!
Germany is already such a advanced country in R&D , it's just that , it came into world news
Ted talks ignore vaccine victims?
*researcherS
They’re originally from Turkey though!!
@@withnora3804 doesn't matter, they are fully German now
An amazing Turkish couple !
@Carl Sagan and still there is this one German word which is used all the time „Ausländer“ which was and is primarily used for Turkish migrants in Germany and it means people from foreign countries in a way to show that we don’t belong to Germany, so nearly every German Turkish person I know sees himself as a Turk as much as they feel like Germans at least and it’s no different with them, so yes they are German Turkish and we are very proud of them
a Turkish *German* couple that was raised in Germany, went to medical school in Germany and found their groundbreaking multibillion dollar biotech company in Germany
@@edithputhy4948yes only with Turkish names you can’t pronounce correctly 😉
They are just human from earth
@@myname1700 rather superficial aren't you, most modern humans can leave such trivialities behind
What an amazing couple who seems dedicated to bring change for the mankind and not just to create profit for themselves and their shareholders. Big cheers to that🍻🙅🥳
Experimental vaccine which is nearly forced everywhere now? Yes big cheers 😅😂😂
@@mnstr2173 with decades of data and research behind it, I don’t think you can call it experimental anymore. Please keep it real, and stop spreading fake information.
Joey gio its experimental. Israel has record covid numbers despite the fact they are one of the most vaccinated😂
So let’s sum up:
- experimental MRNA vaccine
- doesn’t avoid spreading the virus
- since vax new mutant every day🤔
- many horrible side effects
BTW: im asking myself if this is even a real vaccine I mean there are even vaccinated people that got hospitalized there are many different data’s some say 90% hospitalized are not vaccinated but other say 40% are vaccinated so they can’t be trusted
@@joeygio9586 How did animal trials go with these mRNA treatments?
Hmm, I respect that some people does not have confidence in the effectiveness of the vaccines and thus reject it. In my own case the conclusion was that the mRNA vaccine was a better alternative than risking to become infected and transmitting the virus onto others - thus it is also in respect to my fellow citizens. In Denmark the authorities recommend the most of the population to get vaccinated. I put trust in our ministries and those experts who acts as advisers. Does any credible sources point at any major risks in getting vaccinated? To be honest I don't think so but I might be wrong.
Both my (younger) brothers have stage 4 cancers (Prostate and Mantle-Cell Non Hodgkin's) that I hope will be curable soon.
Tell em to be plant based
@@sohaila980 I'm sorry, but I doubt diet will cure cancer. It might help someone be healthier, but telling someone who has probably tried everything to cure something as dangerous as cancer with diet is kinda insulting and dangerous too.
@@applegal3058
And see a healer as everything is energy!
What if I cure them what will you give me?
@@sohaila980 oh my, I don't know how to reply to this... 🤦♀️
@@sohaila980 This is incredibly tone deaf! I can’t believe this!
Elon Musk said a couple of months ago that mRNA is for medicine what software is for computers - everything can be programmed with it.
This is why we need the second Nürnberg
@@oshinsan21 What do you mean by that?
@@DanielWolf555 we are in the middle of the biggest experiment on humanity ever conducted. We are being lied about it, we are being told, this mRNA cannot do anything to us except making us immune to this Spike protein. What you cited tells otherwise.
nobody cares what Elon Musks says and he doesn't know jackshit about medicine
@@edithputhy4948 it's not anymore about medicine. You can invent and experiment the greatest thing in the universe, never created before. The difference is: how do they want to use it? Think about it.
They seem genuine, driven and dedicated to contribute to humanity. What a revolutionizing discovery that can be utilized in bringing advancements in fighting diseases. However it will be crucial that the use of mrna to send informations to cells falls to the hands of well intended scientists.
Give these guys a Nobel prize!
Just like Obama for his drone genocide.
They will get
Totally agree 👍
Absolutely! True pioneers!
„Interestingly, however, the BNT162b2 vaccine also modulated the production of inflammatory cytokines by innate immune cells upon stimulation with both specific (SARS-CoV-2) and non-specific (viral, fungal and bacterial) stimuli.“ - Link Originalstudie
Alexander Kekulé, Virologe: "Es ist wohl so, dass durch die Impfung Abwehrmechanismen gegen bestimmte Viren und Bakterien gebremst werden. Das heißt, ich impfe gegen Sars-Cov-2 und es gibt eine Aktivierung der Antwort auf das neue Virus. Parallel aber wird die Antwort auf andere Viren gebremst. Gegen diese andere Viren ist man dann weniger gut immun.“
Its so interesting to listen someone talk whos turkish lived in germany in eng
The real developer of the bases of the Covid vaccine were KATALIN KARIKO Drew Weissman. Kariko is the weispresident of Biontech
You make us proud! Not only because of your remarkable contribution to humankind, but also because of the significance of your achievements in the ongoing battle against racism and prejudice. The children of “Gastarbeiter” are just as smart, just as hard working, just as resourceful, just as dedicated, just as ethical as any one else in Europe. Göğsümüzü kabarttınız! 🙏🙏🙏🧿🧿🧿👏👏👏
They are also a role model for children with an immigrant background.
and I bet they don't support an authoritarian demagogue like Erdogan unlike certain other prominent German Turks
@@edithputhy4948 look I don’t like erdogan either but they do support Turks so cry abt it ig.
The real developer of the bases of the Covid vaccine were KATALIN KARIKO Drew Weissman. Kariko is the weispresident of Biontech
they'll end up in front of a tribunal.
Thankyou ♥️
Thank you. Thank you. Thank you. Best regards. Tüm calismalariniz emekleriniz için sonsuz teşekkürler.
Danke an euch beide. Greetings from Greece !!
Danke für was?
@@flipperboy7023 danke dass die beiden so viele leben gerettet haben!
@@user-gk9cc2cw4i aha bestimmt ;) hast du schon dein 3 - 4 boostershot geholt?
Thanks
I follow them since i got the diagnosis Ms . I really believe that they one day have a cure for Ms. Just two revolutionary people 🙏
Sorry for hearing that. Right - and the outcome of this new approach might also be a vaccine against AIDS.
I definitely believe that - in our lifetime. It's been years since I pretended to be a doctor, but I know that science can do amazing things for the brain and its muscle control now.
A pleasure to see evidence of people's appreciation for and trust in the scientists and personnel that make up big pharmaceutical companies.
I am wondering what they are saying now about the people who are shedding the spike proteins and making other people sick with the GMO mRNA sarscov 2 proteins?
And why aren’t the receivers given the money they supposed to receive since this is an experimental drug??
Just asking :)
What do you mean with "shedding the spike proteins and making other people sick"?
And it is not an experimental drug as it is already approved. Btw even if it were, there is no law requiring you to be compensated when you are part of a medical trial. So even if it were, your question wouldn't make sense.
Amazing story and articulation. God bless
Gotto love the nazar boncuğu 🧿
Ugur sahins necklace is...😆
@@rumeysa1693 I was looking for that comment :D
The real developer of the bases of the Covid vaccine were KATALIN KARIKO Drew Weissman. Kariko is the weispresident of Biontech
Incredibly inspiring people, I studied mRNA not long ago and cannot believe how far we have come since!
The scientists who make the world better, are my heroes.
War criminals
@@kwisatz_haderach go back to your flatearth channels
@@OsvaldoBayerista Hi bot, is that all you may answer? Besides: I am no flat earthling, no moon landing denier etc. And well, I have a master degree in a natural science subject, you most probably don't. And I can read.
@@kwisatz_haderach How are they war criminals, explain
Gosh, thank you, thank you Uğur Şahin and Özlem Türeci. I don't think there's been a day when I didn't briefly think of you and the incredible work that went into the tiny bit of instruction manual that went into my arm this year to teach my body how to fight the corona virus (my own defence was pretty rubbish - no offence my dear T-cells etc! :)
Incredible how much we now know on how our bodies work, how they can be helped and I can't wait to see what new milestones will be crossed fighting cancer as well!
Thank you too Chris and TED for this wonderful interview.
These are really nice to hear from you! Thank you for sharin your sincere thoughts and please don’t go hard on ur T-cells :)
@@emrecck I’ll try. They definitely got a workout this year!
Very disappointed with TED re fast track vaccines
Great minds from 🇹🇷 Turkey, living and creating in 🇩🇪 Germany.
Great minds that were very much developed in Germany .
Thank you so much for everything. I hope by this invention could be finding a solve for the rheumatism because it is very hard to live with that !
We need more people like them who want to change the world! 🙂🤟🏾
The real developer of the bases of the Covid vaccine were KATALIN KARIKO Drew Weissman. Kariko is the weispresident of Biontech
yes, a few more of them and the world population will be erased.
I love you Ugur. Last year I invested most of my money in biontech stock and literally tripled my money.
Cool you tripled your Money and People died from the Shot. Proud on yourself?
@@jamoin4310 Even if that´s true, this shot saved so many lives, it´s not even comparable.
@@nosteinnogate7305 you re absolutely right, but response it what he wants. Best way to deal with those people is “…don’t feed the troll…” the oldest and most underestimated rule in the internet😉
@@jamoin4310 the flu shot kills people too, did you check any vaccine?
blood money
Vielen Dank! Sie haben so viel für die Welt, für die Forschung und für die Integration getan!
Truly couple goals!!!!! I want to find my scientist lover/medical doctor one day!!!
Cringe
Same Here ;(
I would have liked to hear their response to the touted adverse effects of their vaccine.
Me too !
Couple of the year maybe Century
this new decade probably
Most amazing and hopeful episode !!! Thank you 🙏🏻💖🌹
don't you look at the stats?
Doctors like this deserve so much more than all the Kardashians and the Trumps of the world
Oh so Trump made the vaccine work, I completely miss that! Thanks for educating us!
YES THESE PROFESSORS ARE TURKS AND THEY HELPED PEOPLE OF THIS WORLD!!🤘🇹🇷
i appreciate the work they did
Such an inspirational Couple..
Love ur vdos ❤️❤️❤️
Great!!
I'm proud 🇹🇷
You've got to be modest, respectful, unassuming, courteous, demure, discreet and modest to achieve extra ordinary accomplisments......therefore hat off to them.
It's so amazing they are Turkish and they help to the world at the most dangerous time such a proud of you thank you Mr uğur and özlem
They are kurdisch not turkisch
@@Cor_C i just say it because every turkish people say they are turkish. Why they don't say they are kurdisch? Is that so difficult? I never heard in any video about them both that a turkish man or woman said "i am proud of our kurdisch people". They don't do that. And that fucked me up ;) they act like they have found the vaccine.
@@b.u5826 they never spoke one word kurdish or ever shown an sign of it what they did is they talked in turkish
@@b.u5826 and iskenderun ist an city with mostly turks btw you can see that there are even no hdp voters mostly they vote for Chp or Akp
@@b.u5826 if any turk has succed you kurds always claim they are kurdish or whatever
inspiring people!!
THEY ARE TURKISH PROFESSORS AND HELPED PEOPLE OF THIS WORLD!!TURKS ARE PROUD!!!🤘🇹🇷
It's a pity that current Turkish politicians are hostile to such science and startups. Even without reading their biography first, I KNEW it that they had to leave Turkey and build their career somewhere else in order to become successful. Then I googled them and my thought got confirmed. Almost no talent seems to be getting suported by the govmnt in Turkey, even though Turkey has intelligent people. Hopefully, that will change in the near future!
@@NoctLightCloud You are completely wrong by on purpose saying current Turkish politicans are hostile to such and startups. It is obviously you prefere to tell wrong things or twist the truth only to support your own political opinion.. You know that Türeci and Şahin's families immigrated to Germany not during "current politicians" but long ago in 1960's... Where did Özlem Türeci and Uğur Şahin have to leave? What are you talking about? You googled but didn't understand anything written or changed whatever written into lies..
@@ouyeht 60s Turkish govmnt was as hostile towards new companies and money-intensive research as today's. How come so many European countries allowed for progress but never Turkey? As if Turkey would've supported mrna research like that! That today's Turshish govmnt is no better than in the 60s says it all. How come nothing a Turkish person achieves internationally comes from a location in Turkey? Please prove me wrong, I would like to be wrong in this regard. They always have to leave Turkey first to make it, and you being angry at me does not change that fact.
@@NoctLightCloud You know that you are lying, the things you said are not true but totally lies... Turkish goverment is not hostile to new companies at all but you are obviously very hostile to current Turkish government.. Sırf kendi politik tarafınızı desteklemek için "ingilizce" yalan şeyler yazıp, kendi ülkenize düşmanlık yapmanız, olmayan şeyler yazıp kötülemeniz, "laf oyunları" yapıp her fırsatta Türk devletini kötüleme çabanız savunduğunuz tarafın ne kadar yanlış olduğunu ispatlıyor zaten...
Gururumuzsunuz! Thank you for spending your life for science and humanity! ❤️✌️
Öylemi? Ondan mi Almanyadan kactilar?
Couple goals
Proud and honourable couple
I am proud of them as a Turkish person and a human:)
what has your turskish nationality to do with it? They arent even turkish but german with an turskish ethnic background.
@@dieNatoren sorry that you are offended mister chad not like I am allowed to speak or anything
@@dieNatoren So? Do they deny that they're Turks?
@@dieNatoren don’t be so jealous!They are Turks with German education.Or you don’t want to accept the idea that Turks saved the world?😂
@@dieNatoren Ok boomerr! now go back to your dump
So proud of them.Devotion, compassion, and humility.
Why are the testing protocols not scheduled to be complete until 2023?
Because it's normal to keep monitoring study participants for years...
@@meamzcs thats after the trials have been completed
@@meamzcs it took the vampires around 15 years to take thalidomide of the market.
@@terrific804 you can't compare this to normal drug or vaccine development and yoi ESPECIALLY CAN'T COMPARE IT TO THAT... A big part of the safety measures for drugs we have today is BECAUSE of that drug... Back then there were essentially 0 things you had to do to be able to sell a drug. No in vitro, no animal models, no phase I, II, III studies before approval. Normal development is focused on business risk reduction and bureaucratic processes eat into a lot of time... The combination of these two things is why it usually takes years upon years... There are absolutely no side effects to expect from a vaccine later than 2 or 3 months after the shot... Literally no vaccine ever had that and it doesn't make any sense...
@@meamzcs when is it normal to make the world population study participants? Do these people know they are study participants? I thought it was settled that it was safe? What are they studying then?
❤️
Great team🧿
I'm proud to be a Turk thanks to them! Such inspiring souls!
how so? what did they achieve, indeed? the Pfizer vaccine still needs trials.
Well, one was born in germany and the other moved to Germany when he was 4 years old. They would have never been able to do this research in Turkey.
well one was born in Germany and the other moved there at age 4 so
@@derriegel5705 falls der Impfstoff eine Katastrophe gewesen wäre, würde man bestimmt von den "türken" reden .. anders rum sind das natürlich perfekt integrierte deutsche :)
@@derriegel5705 they have turkish blood !!!
Every day the technologycal possibility given by mRNA vaccines amazes me. It goes even beyond corona and cancer into matters dealing with the immune system. Congratulations!
they look dangerously smart
What about adverse effects???
❤️❤️❤️❤️❤️❤️❤️❤️
These people give me hope for the future
I can see a nobell prize coming their way.
There will be no nobel prize for Mr Sahin and Mrs Tureci bc mRNA technology is not a new discovery and was studied by thousands of different scientists before BioNTech was even founded. It's not certain who would even be considered for the prize bc it was a group effort but two of the leading scientists in this matter are Katalin Kariko and Drew Weissmann.
Nobel prizr for being murderers m
Great scientists! We owe a lot to them and all the other great scientists in their teams!
True champions thank you!!
amazing really what has been done
I’m not against mRNA vaccines, but I do think it’s interesting that the word “safe” was only brought up once in a fleeting comment, whereas the topic of “speed” was touched on many times.
Don’t take it!!!
inacctivated vaccines are not available in the west, i'm never taking dna engineering stuff especially when they dont make sense how they describe it works
Maybe cancer, hashimoto's and many other diseases will be treated by this mRNA technology in the future? Thanks to all Scientists who dedicated their lives for a better world!...
Thank you both for your immense work!
according to them they had the so called "vaccine" mixed within just a few hours.
give them the Nobel already
If they were British it would be mentioned in each sentence, but they are German and German taxpayers money played a crucial part in developing the vaccine
How come? They own a private company and funded by private donors, they are partnered with Phizer. Do they get fund from the govment?
@@nh7568 Yes, 375m Euro were provided to BioNTech by the German federal government.
@@tylerethernet8610 thanks! Also just read that they received funds from EU R&D programmes so perhaps not just German taxpayers. That said, Phizer invested 2 billion USD to vaccine development so government contribution is smaller when compared.
What a likeable couple. Thank you very much!
It really is good to see Özlem Türeci. We do not always have a chance. I don't the reason.
You've been an inspiration for all Turks and all humanity, thank you Özlem and Uğur! 🇹🇷🇩🇪
And all the germans! I
@@dieNatoren right!
Sizinle gurur duyuyoruz iyiki varsiniz🙏❤️
Thanks to the two turks❤️🇹🇷❤️
RESPECT
THANK YOU SO MUCH!!!
This couple is awesome and gives me hope for human kind!
The real developer of the bases of the Covid vaccine were KATALIN KARIKO Drew Weissman. Kariko is the weispresident of Biontech
knowing what's going on one needs to have a strong believe in god to not lose all hope. Justice will find them.
All the negative feedback are being deleted,
So who is not telling the truth, these two or Dr. Robert Malone as he has clearly went on record now how he invented this technology
Yeah, kind of a weird situation.
Both are telling the truth. Dr Robert Malone's team invented the mRNA vaccine platform, others like BNT developed the first commercial mRNA vaccine.
@@colint3941 He was one of many who had the idea. But his research never got remotely far enough for it to be useful in any way as he couldn’t get it to be stable. That’s where other scientists and these two came in who developed it so that it can exist and be stable in the body of animals and humans which is where it first even became useful in any way. Malone wants praise from the scientist community and claims the entire thing when in reality he is just one little screw in this massive machine that the use of mRNA is. What he’s doing now is the last resort after realizing his impact wasn’t too great and he’s just another guy, it’s sad to see but the praise he gets now is from uneducated alt-right idiots who use him as a kind of legitimator for their wildly inaccurate claims and he goes with it bc it’s his last option to “claim“ this invention that really isn’t his.
Harika,teşekkürler
Great team! We're proud of you! 🧿🧿
not everyone is proud of you.
Impressive and inspiring - und ein großes Danke 🙏🏻😊
Watch these two, they might cure cancer soon! I am generally against billionaires, but this might be an exception, seeing that they seem genuinely interested in the general good. So inspiring! ♥️
Are they Billionaires ? ... that can only be from vaccine profits then ?
@@SuneRicardo you have no idea what you qre talking about so i would stop . Ofcourse they will earn some money by vaccine but the main gain was from share price increase of biontech
@@SuneRicardo They own 17,5% of Biontech stocks
@@Leon-ur5uk anything else would be wierd … honestly thought they would own more than that .. :)
❤️❤️❤️👑👑👑
❤❤
I thought Dr. Robert Malone was the inventor of the mrna vaccines?
He is a pioneer in the field, an inventor of the technology / platform for mRNA vaccines.
He was one of those who had an idea in the direction but didn’t pursue it very far
In the most genuine way, science is a real-life video game. Dr. Özlem Türeci explains "dendritic cells are coaches of the immune system. They are the generals which call all the different special forces and train them on the wanted poster of attacker." Highest respect for scientists.
Love them cant wait to see what they do for cancer
That time is 2026 years..
We are proud of you.from İskenderun with love
Nobel Peace Price for giving Men Myocarditis!
Not only myocarditis
Very impressive, indeed.
yes, no one helped so many people to get six feet under so easily and made so much money by doing this, while being ironically celebrated by the sheep.
ne güzel insanlar. yolları açık olsun