Retinoblastoma

This is a lecture about the medical condition retinoblastoma, with a focus on genetics, intended for trainees and medical professionals. Video by Gabrielle Lakis, BA. Script by Angela Chen, BS. Edited by Philip M. Boone, MD, PhD. We acknowledge Dr. Rachel Brennan for helpful input on the script.
References:
OMIM: www.omim.org/entry/180200#phe...
Genetics home reference: ghr.nlm.nih.gov/condition/ret...
GeneReviews: www.ncbi.nlm.nih.gov/books/NB...
Harbour JAMA Ophthal 2001: jamanetwork.com/journals/jama...
Rarediseases.org: rarediseases.org/rare-disease...
Vogel Hum Genet 1979: www.ncbi.nlm.nih.gov/pubmed/3...
Dyson Genes Dev 2016: genesdev.cshlp.org/content/30/...
Yun et al. Int J Ophthalmol. 2011: www.ncbi.nlm.nih.gov/pmc/arti...
Hanahan and Weinberg Cell 2000: www.cell.com/cell/fulltext/S0...

[@annaclaire1482]

This video is just perfect, I'm a visual learner and now I'll remember this forever 😻 thank you!!

[@jesiraj2448]

Great presentation...Thank you very much. Kindly consider to upload more BCG, Cyto and Molecular lectures as well.

[@reemwehbe3386]

Great presentation 👍

[@thacompilations4010]

Excellent!

[@mohankumark6601]

Great lecture too the point❤

[@python2.1]

A very helpful video to get a concise yet well explained background knowledge before I finally kill my brain cells with my text book. Thanks 😊

[@rito8867]

Thank you so much

[@SaurabhYadav-co7mq]

Great video,
Thanks and Keep it up😄

[@medicmandan2554]

really helpful, thank you!

[@sallylakis544]

Very clear explanation and well done video!

[@dananjanirathnayake5059]

Great video

[@shanaw5445]

Did you remove your video on Aicardi syndrome? I can't find it :(

[@qudratullah2459]

Please tell me that Diseases is treatable or not?

[@annaclaire1482]

It's treatable. Using a combination of chemotherapy and local treatment (with cold or laser), 90% of patients are cured and the majority of them also retain eyesight in the affected eye. However, patients with an hereditary RB1 mutation, who survive this pediatric cancer, are at high risk of developing other types of malignant tumors in adulthood.

[@mrbee1611]

Let me question something do you know where you will go after you die? If not let me say something after you die you can have a choice to either go to hell or heaven see 2000 years ago there was this man named Jesus who died on the cross for our sins and rose alive 3 days later all because he truly loved us he died for us so I question you now do you truly believe in Jesus or do you live for the world turn to Jesus Christ trust in him Christ has way much more to give than the world he loves us turn to Christ

[@python2.1]

He died , then he was born , well he ain't dead so......

[@teenmomAT14toRN]

Amen ❤❤❤

[@statusburning4113]

Just got done watching the first part on how you get it. Actually, you don't get it. *You're born with it.* That really sucks...