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Methionine Metabolism and Activated Methyl Cycle | Pathway and Purpose
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- čas přidán 17. 08. 2024
- Lesson on Methionine Metabolism and the Activated Methyl Cycle. Methionine is a sulfur-containing essential amino acid, which can be processed within the activated methyl cycle to produce s-adenosyl methionine (SAM) and tetrahydrofolate (THF). Methionine can also be metabolized to succinyl-CoA, which can then be utilized in the tricarboxylic acid (TCA) cycle to generate ATP. Two enzymes in these pathways, one in the activated methyl cycle and the other needed to produce succinyl-CoA, require vitamin B12 for there utilization.
Hey everyone. In this lesson you will be introduced to Methionine Metabolism and the related Activated Methyl Cycle. We will also discuss the purpose of the activated methyl cycle, the enzymes involved in each pathway, which vitamins are required for enzyme activity, and how methionine is converted into succinyl CoA for energy production.
I hope you find this video helpful. If you do, please like and subscribe for more videos like this one. :)
JJ
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JJ
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I'm a med student writing a paper that involves the homocysteine pathways and whatnot. Your videos are the only videos that show the whole picture. In First Aid and most places they only show homocysteine being converted into cysteine and don't show it's eventual conversion to MMA. I don't think I can cite your video in the paper unfortunately. I was wondering if you had a source that showed this entire pathway? I can find sources for bits and pieces but not the whole thing for some reason?!?!? Your videos have been super helpful for me!!! thanks for making them!
Excellent presentation, thank you very much for sharing.
Fantastic! The videos of biochemistry of the JJ Medicine are amazing!
Question..... can anyone explain or give clarity on the following ... does any change to typical Purine & Pyrimidine, folate, B6 or B12 pathways during pre or early post natal periods result in heritable genetics that could be passed from that baby should they procreate in later life?
8:45 but where did the inorg. phosphate go? from ATP to ADP
grateful to have your videos.
thanks for this video. I was studying coenzyme A synthesis and somehow came to this video. very entertainingand very instructive video. I drawed all molecules ina paper in case I want to look at it again. Thanks again :) keep up the good work
very, very, very helpful
Good stuff
this was super helpful. thank you so much!
this is very helpfull thank uuu
Great video! Been looking for this explanation.
Subscribed at first sight😍
Sick sn dr
Is it the percusor of Sam E ? Taking Sam e but a little bit expensive may I use L-METHIONINE instead of Sam e ?
Can I say the methionine cycle is ATP consuming?or the adenosine regenerated can compensate the 1ATP used?
What's required for Adenosyl-Homocysteinase activation
Thank you!
Bravo
Is it possible for a person to be deficient of methionine? If yes, what is the reason for such deficiency?
Yes dr masterjohn has a website link for methionine and glycine balance. The more protein you eat the more glycine you need. Eating skin on bone in helps. Adding extra collagen powder, glycine powder.. Can help. He lays it out well so i hope you cqn find it. Armstrong sisters also have good info on this.
So what’s the main point here?
SAM uncle