Hemoglobin moves O2 and CO2 | Human anatomy and physiology | Health & Medicine | Khan Academy
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- čas přidán 6. 12. 2012
- Learn the two ways that oxygen moves from the lungs to the tissues, and the three ways that carbon dioxide returns from the tissues to the lungs. Rishi is a pediatric infectious disease physician and works at Khan Academy. Created by Rishi Desai.
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You explained this so beautifully it makes me want to cry.... I've been freaking out about not understanding this, but now I do, so thank you!!!!!
Absolutely! I will get this done soon...
Why can't you just reply to the user instead?
@@9-volt247 11 years later💀
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I learned this in class!..... But that took 2 months and this took 14 minutes
That's because you worth that one month. It always feels like we don't know anything. But in reality our mind collects those little information that are easy to learn about that. That made us easy to learn it later. And it felt like we're reading it for the first time. But when we see all those things twice. We started thinking like yeah.. I think i know a bit about it.. But it just slipped off my head.. My way of reading something i 1st catches the things that are easy to memories.. And repeat them..and while repeating as revision i do recall those words or lines that i don't understand. And then i work on it. If it seems intresting as well as important. I just do not force my mind to attain 90% of concentration at each topic. But after a large break. I first pick up all those hard points. & lastly reexplain everything that i had learnt.
Check out the video on the Bohr effect and Haldane effect. =)
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The video does explain the concept in a very detailed but concise manner.... The point about the chloride shift (Hamburger Phenomenon) could also have been included.....
you are absolutely amazing :)
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Thank you
Very nice videos. Hav u guys made any videos on ventilation perfusion mismatch in lungs especially discussing increased dead space due to thrombus in pulmonary artery. Can't understand.
Khan, how can I give you feedback? Many videos have minor errors, e.g.
H+ and CO2 do not bind to the same site as O2, so it doesn’t kick O2 off, but it binds somewhere else and lowers the O2 affinity of Hb.
Also equations reverse in the lung because CO2 is being lowered, i.e. as it comes off of Hb, it lowers Hbs affinity to O2. Not that O2 coming aboard kicks off CO2.
so the O2 does not get kicked out of the car...there is simply less room in the car for O2?
Incorrect analogy
More like.. The more country kids (CO2) show up to the drive-in and hop in their friends' trucks (amino binding site), the less the rockers (O2) want to chill at the drive-in, so they jump out of their Nova's (heme binding site) and peace out. The more that leave, the more cowboys show up and visa versa, depending which side of town drive-in they go to (lungs vs. thigh/glutes etc).
Thank you for this! As I was listening it didn't seem quite right...
loved the vid by the way
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I did
But errors
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Great job bro..........waiting for videos
My teacher was harsh and put this on a question sheet for year 7s. This really helped. Thank you !
I have a slightly off-track question for you about SpO2 vs SaO2 cuz i'm having trouble finding an answer: apparently both measurements can be read by a pulse oxymeter. However, is it true that SaO2 can only be read by blood sampling through an i-STAT reading. I'm a little confused.
Thanks for the videos, really well explained. What program are you using for this videos?
wow
Damn this guy is insane. What a great teacher
In my text book it says that O2 binds with the heme group of the hemoglobin molecule and CO2 binds with the amino acids in the globin part of the hemoglobin molecule, therefore o2 and co2 do NOT compete.
you elaborate more on co2 and h20
same question i do have
hey can you do a video on the Intrinsic and Extrinsic Pathways of Coagulation?? :)
The Blueprint of Life and Wellness
Does the blood from the thigh not go to the heart and then the pulmonary artery where it is transported to the lungs?
Rishi, I have a question: My anatomy textbook says that C02 doesn't bind to hemoglobin in the same area as O2 (the heme group). So, is it correct to say that CO2 "bumps off" O2 when it encounters oxyhemoglobin in systemic circulation?
what app are you using? great vid
I've got a question, the protons formed in the carbaminohemoglobin are they still binding to another molecules of hemoglobin or they're still bind with the COO-?
What happens with the chloride? HCO3 wont get out by himself, it will be an exchange with Cl. What about that?
Sir how many molecules of co2 carried out by the hemoglobin. ?
When protons competed for hb oxygen lost it ( At the thigh cells )and when oxygen competed for it, protons lost it ( Alveoli ). How is that possible and why ? Please explain. That curiosity burns me from inside.
when the O2 competes for hB and forces the release of HCo3 and H+ in the RBC is that the Bohr effect? and when the H+ competes for hB, releasing O2, is that the Haldane effect?
damn will i learn about proteins and acids in anatomy and phyisiology?
I didn't think H+ competed with oxygen because they bind at different sites on the Hemoglobin. Where does the H+ ions bind to on the hemoglobin? to the histidine? lysine? propionate group? I believe it may be the c-terminal histidine group but I am not sure. Could someone clarify?
The Seahawks should of run the ball
I might have to watch this video more 5 times
I think you are mistaken when CO2 binds with oxyhemoglobin, it forms just carboxylhemoglobin and O2, no H+ protons
The reaction frees a hydrogen and the T state is stabilized by its uptake due to dimer/dimer ionic interactions
Yeah
Can hemoglobin bind to oxygen and carbon dioxide simultaneously?
Yes man
CO2 splits up in CO2- and H+. Then CO2- combines with Hb and H+ is released.
i hope i am right.
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Where can i take a chemistry class as refresher ? So i can better understand human antomy D: im going to be RT but im WEAK in sience
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Im having trouble understanding the bicarb, pCO2 system for clin chem can someone please explain?
In respiratory acidosis, pCO2 is increased. So the compensatory effect is increased HCO3-. All of my notes say that kidneys retain bicarb. How does retention of bicarb increase bicarb?
I'm stumped on that one too...if you've found out please tell me :)
why oxygen binds to iron if iron 2+ and already binded to four nitrogens and one globin. How oxygen finds place in this complex substance?
"Hemoglobin" is Spelt "HAEMOGLOBIN" :O
+Joe Conville US vs British Spelling like color vs. colour.
Audio tech comment only - Your voice level seems to be a bit too high for the system ie. The meter is in the red ; ) - and distorting. Respectfully.
Thank you, but just one problem, you said : CO2 + HbO2-----> Hb.coo- + O2 + (H+) from where is coming this H pro to?? and as well the negative charge on Hb.COO- ??
Thanks
The proton comes from one of the oxygen atoms. If we remove a proton, the atom becomes negative. I hope this answers both of your questions
Yes, it does, thanks
Great video!
Does a increased overall CO2(and decreased pH) level from lung desease from e.g smoking, mean the affinity of the O2 in the lungs?