Dr. Risinger explains the latest data on tirzepatide for treating obstructive sleep apnea from the SURMOUNT Trial. More info on SURMOUNT TRIAL: pubmed.ncbi.nl...
I’ve been on Mounjaro since august of 23. A1C has dropped to 5.4, sleep apnea has really improved. Weight was 303lbs, now it’s 224 and still dropping. This is the best drug ever.
I experienced large improvements in sleep apnea, Triglycerides down to 35 , LDL reduction, HDL improvement to 55., cut my BP meds to 25% of starting dose, A1c down to 4.8 from 6.0, probably, but not certainly, only due to the weight lost of 15% I experienced with GLP-1 drug over a period of 12 months. This a profound change in health biomarkers. A glaring issue is the price vs the cost manufacture these peptides. They are cheap to produce, the price should be dropping by 75% of more due the volume sold. It has not decreased even by $1.00. That is a shameful thing for the pharmaceutical industry at this point.
One has to eat low carbohydrate to lose the weight not only for the apnea, but to avert becoming T2 diabetic. I battled with this for over 30 years and got it figured out and yes I still use a CPAP, but the machine setting is down from 14 to 9 with only 1 episode a night now. Lost 30 pounds with the diet change and no drugs.
I am one of those people who love my bipap. I have been using such a along with Adams nose pillows since about 2001. Took me about three days to get used to it and to wear it all night. But I guess I’m one of the lucky ones.
My SLEEP PARTNER is Cork, a 7 y.o. Yellow Labrador retriever. She has never left the bed nor complains about my snoring or the CPAP ssssshhhhh Better ssssshhhh than another Drug in me.
I agree and applaud your efforts Dr Christine on trying to help patients with a myriad of health issues that peptides seem to help, when used correctly these hormones are so beneficial and life saving.
Right....a new indication for diabetes drug. Gotta find another cash stream out there. I think I'll stay with my cpap machine. BTW retired pharmacist here😊
Same. It took me about 6 months to figure it out, reading everything, finding the mask, N30, and understanding that if there will be high humidity in my room, it means I have to adjust the setting for that night. I don't have any side effects with my stomach, digestion, nausea and all the other things the medication warns about. I sleep soundly and quietly. Honestly I think I would miss it now if I didn't have it.
I hug (ha) my APAP every night. If forgotten on a trip - it is a turn around and get it moment. With weight reduction, I have been able to reduce the pressure settings. One thing I learned early on was the mask type (nose pillows) and wearing shapewear to help totally expel air during nights. That took some experimentation. Now..zzzzzzzz
I love my APAP machine and look forward to putting it on at night after nearly 60 years of undiagnosed OSA/CSA. It has radically changed my life. Would I like to chuck the machine and still be free from OSA? You can bet your last dollar I would! Thank you for posting this video!
1) If your (untreated) AHI is greater than 15 and and you reduce it by 63%, it will still be greater than 5, you will still have sleep apnea and you should still use a CPAP. 2) If your AHI is less than 5 when using CPAP and you reduce it by 63%, that could be a notable improvement, but it does not necessarily mean that you can stop using the CPAP. 3) This is just physics - CPAP does not FORCE air into your lungs. Flow occurs because of pressure difference - from high pressure to low pressure. Pressure in mask and lungs is equal at the end of one breath, just before he start of another. Inspiration occurs because the muscles expand to reduce pressure in the lungs to be lower than mask pressure, Expiration occurs because the muscles contract to increase pressure in the lungs to be higher than mask pressure. Your body controls this, not the machine. 4) BiLevel, however, change mask pressure so that it does increase pressure difference between lung and mask, for both inspiration and expiration, and so tidal volume increases. However, this makes breathing easier, not harder. 5) A significant reason people fail with CPAP, remove their mask and struggle to breathe is because their settings are wrong. The systems in place to support users and help them to find appropriate settings is failing through lack of knowledge (not helped by the lack of relevant information about the machines from the manufacturers), false acceptance of catchy, but incorrect, statements by the manufacturers, and ignorance of the data captured by the machine or how to use it. Disclosure statement: I like breathing, I love my BiLevel.
I know for fact that I don´t have the sleep apnea. I was tested like 2 years ago, I slept one night with the Darth Vader mask on and the device attached to my wrist. The value what regulate the sleep apnea needs to be more than 5 if you have the apnea, but for me that value was 3. So I don´t have it.
Good presentation. Is it possible that the weight loss was the main cause of the improvement? My sleep doctor said that if I lost the weight I could go off the CPAP.
I do very well on my CPAP machine. I sleep well with it. Would the medications benefit me? I have type II diabetes. And have been prescribed Ozempic. Would the medications interfere with my use of Ozempic?
How do endo docs feel about you promoting yet another justification for using this med for weight loss, when diabetics across the country can't locate pharmacies with enough stock for diabetic issues? We know diabetics who have to scramble from pharmacy to pharmacy...quite often ending up having to skip doses....and once ending up in the ER because of it. How does your "harm none" oath justify the promotion of this drug for weight loss, when it takes it out of the hands of diabetics, and puts their health at risk? You are correct about one thing though - that IS a very small study group. I think one of the key points folks need to be aware of, and you alluded to this when you referenced IF the folks in the study could tolerate the drug. By tolerate do you mean NOT have the typical nausea, vomiting and diarrhea side effects that come with the drug?
Sleep apnea technology designers should invent a machine that follows the normal rhythm of human respiration. Air in, air-out. Instead they produce a machine that acts as a super-charger to force the air into the lungs as if the lungs were a turbine. CPAP's are absolutely pathetic. They are designed by a bunch of morons with no clue about how the basics of biology work. All the styles are uncomfortable in the mask area, whether full face or whatever. The humidity and other settings are clumsy and difficult to use. They all pump air gently for the first few minutes, and then force a hurricane down your throat. I tried different types for months. They are the sleep equivalent of filling your shoes with sharp objects and trying to walk on them. Only about one person in ten can use them, and anybody else that can't are looked down on a "wimps'.
@@roberthunter6927 Ok well there are other machine types. You said you wanted "a machine that follows the normal rhythm of human respiration". First there is BiPAP which offers different levels of pressure of inhale and exhale. Then there is ASV, described as "Adaptive servo-ventilation (ASV) machines monitor a person’s breathing while they sleep and deliver customized air pressure to stabilize breathing. The main difference between ASV and CPAP machines is that ASV machines deliver air pressure dynamically, adjusting according to the person’s breathing patterns, whereas CPAP machines deliver a set level of air pressure throughout the night. Each device has specific benefits depending on the type of sleep apnea." As for masks being uncomfortable. This is true. There are some masks that are better depending if you can breathe through your nose or not. If you can breathe through your nose look into the Bleep Eclipse which is a maskless solution. That one is tough to get into Australia at the moment, so if you can't get that there is a new mask I got recently I'm enjoying: Phillips Dreamwear. Much less cumbersome.
@@travv88 Thanks Trav. I will look into it. Yes, Oz is not the best if you want to get something unusual. In the meantime, i have stopped smoking and lost a little weight. It helps a bit.
Why doesn't this doctor tell people to change their diet and eat proper human food ? You can get off your CPAP and remove sleep apnea by eat a clean carnivore diet.
I’ve been on Mounjaro since august of 23. A1C has dropped to 5.4, sleep apnea has really improved. Weight was 303lbs, now it’s 224 and still dropping. This is the best drug ever.
Carnivore Diet.
Dr Ken Berry, Dr Anthony Chaffee and Dr Shawn Baker.
You can get off your meds and reverse sleep apnea by simply changing your diet.
I experienced large improvements in sleep apnea, Triglycerides down to 35 , LDL reduction, HDL improvement to 55., cut my BP meds to 25% of starting dose, A1c down to 4.8 from 6.0, probably, but not certainly, only due to the weight lost of 15% I experienced with GLP-1 drug over a period of 12 months. This a profound change in health biomarkers. A glaring issue is the price vs the cost manufacture these peptides. They are cheap to produce, the price should be dropping by 75% of more due the volume sold. It has not decreased even by $1.00. That is a shameful thing for the pharmaceutical industry at this point.
Big Pharma doing something shameful for a profit??
Tell me another tale.
One has to eat low carbohydrate to lose the weight not only for the apnea, but to avert becoming T2 diabetic. I battled with this for over 30 years and got it figured out and yes I still use a CPAP, but the machine setting is down from 14 to 9 with only 1 episode a night now. Lost 30 pounds with the diet change and no drugs.
I am one of those people who love my bipap. I have been using such a along with Adams nose pillows since about 2001. Took me about three days to get used to it and to wear it all night. But I guess I’m one of the lucky ones.
Why didn't you list the side effects? It's only fair.
My SLEEP PARTNER is Cork, a 7 y.o. Yellow Labrador retriever.
She has never left the bed nor complains about my snoring
or the CPAP ssssshhhhh
Better ssssshhhh than another Drug in me.
I agree and applaud your efforts Dr Christine on trying to help patients with a myriad of health issues that peptides seem to help, when used correctly these hormones are so beneficial and life saving.
No thanks. I’ll stay with my CPAP. Best sleep I’ve ever had.
Right....a new indication for diabetes drug. Gotta find another cash stream out there. I think I'll stay with my cpap machine. BTW retired pharmacist here😊
@@babyboomer9560 Great. I’ve been using my CPAP for 24 years. Best sleep I’ve ever had.
Same. It took me about 6 months to figure it out, reading everything, finding the mask, N30, and understanding that if there will be high humidity in my room, it means I have to adjust the setting for that night.
I don't have any side effects with my stomach, digestion, nausea and all the other things the medication warns about. I sleep soundly and quietly. Honestly I think I would miss it now if I didn't have it.
Agree 100%,the last thing I want is another chemical application into my bloodstream
I hug (ha) my APAP every night. If forgotten on a trip - it is a turn around and get it moment. With weight reduction, I have been able to reduce the pressure settings. One thing I learned early on was the mask type (nose pillows) and wearing shapewear to help totally expel air during nights. That took some experimentation. Now..zzzzzzzz
I love my APAP machine and look forward to putting it on at night after nearly 60 years of undiagnosed OSA/CSA. It has radically changed my life.
Would I like to chuck the machine and still be free from OSA? You can bet your last dollar I would!
Thank you for posting this video!
when drug companies start looking for other ways to get thier product approved for use it's a red flag for me.
Ik, she said such a suspicious thing so casually lol
Doctors....
Great info, thank you!🦅
I’d also consider a Mandibular Advancement device with or without cpap.
Sounds to me. I hope the government don't drag there feet on this.
I have mostly eliminated apnea through large weight loss (55 lb in the last year) and persistent daily myofunctional therapy.
1) If your (untreated) AHI is greater than 15 and and you reduce it by 63%, it will still be greater than 5, you will still have sleep apnea and you should still use a CPAP. 2) If your AHI is less than 5 when using CPAP and you reduce it by 63%, that could be a notable improvement, but it does not necessarily mean that you can stop using the CPAP. 3) This is just physics - CPAP does not FORCE air into your lungs. Flow occurs because of pressure difference - from high pressure to low pressure. Pressure in mask and lungs is equal at the end of one breath, just before he start of another. Inspiration occurs because the muscles expand to reduce pressure in the lungs to be lower than mask pressure, Expiration occurs because the muscles contract to increase pressure in the lungs to be higher than mask pressure. Your body controls this, not the machine. 4) BiLevel, however, change mask pressure so that it does increase pressure difference between lung and mask, for both inspiration and expiration, and so tidal volume increases. However, this makes breathing easier, not harder. 5) A significant reason people fail with CPAP, remove their mask and struggle to breathe is because their settings are wrong. The systems in place to support users and help them to find appropriate settings is failing through lack of knowledge (not helped by the lack of relevant information about the machines from the manufacturers), false acceptance of catchy, but incorrect, statements by the manufacturers, and ignorance of the data captured by the machine or how to use it.
Disclosure statement: I like breathing, I love my BiLevel.
Side effects. ?
I know for fact that I don´t have the sleep apnea. I was tested like 2 years ago, I slept one night with the Darth Vader mask on and the device attached to my wrist. The value what regulate the sleep apnea needs to be more than 5 if you have the apnea, but for me that value was 3. So I don´t have it.
Oh, thank God!
Good presentation. Is it possible that the weight loss was the main cause of the improvement? My sleep doctor said that if I lost the weight I could go off the CPAP.
She said that she thinks so.
@@Ayverie4 I got carried away.
I want to try it
I do very well on my CPAP machine. I sleep well with it. Would the medications benefit me?
I have type II diabetes. And have been prescribed Ozempic. Would the medications interfere with my use of Ozempic?
It would replace Ozempic. Talk to doctor.
Awesome news for the wives of chubby men who snore! 🎉
Sound🎉
How do endo docs feel about you promoting yet another justification for using this med for weight loss, when diabetics across the country can't locate pharmacies with enough stock for diabetic issues? We know diabetics who have to scramble from pharmacy to pharmacy...quite often ending up having to skip doses....and once ending up in the ER because of it. How does your "harm none" oath justify the promotion of this drug for weight loss, when it takes it out of the hands of diabetics, and puts their health at risk? You are correct about one thing though - that IS a very small study group. I think one of the key points folks need to be aware of, and you alluded to this when you referenced IF the folks in the study could tolerate the drug. By tolerate do you mean NOT have the typical nausea, vomiting and diarrhea side effects that come with the drug?
Blame the drug companies, not people looking for better health outcomes.
try to lose weight to reduce sleep apnea
Carnivore diet.
I am scared of pharmaceuticals and doctors.
Carnivore Diet will help you stay away from doctors and Big Pharma.
At this point I trust the drug dealer on the corner more than I trust these legalized drug dealers. No thanks, I'll stick with CPAP
I'm so sorry that you're tired of my crap. I'll try to be nicer next time.
Sooo the other option is ... lose weight. 🙄 And this doesn't help you if you're not obese....
Kiniseology tape your mouth shut, thank me later
Sleep apnea technology designers should invent a machine that follows the normal rhythm of human respiration. Air in, air-out. Instead they produce a machine that acts as a super-charger to force the air into the lungs as if the lungs were a turbine. CPAP's are absolutely pathetic. They are designed by a bunch of morons with no clue about how the basics of biology work. All the styles are uncomfortable in the mask area, whether full face or whatever. The humidity and other settings are clumsy and difficult to use. They all pump air gently for the first few minutes, and then force a hurricane down your throat. I tried different types for months. They are the sleep equivalent of filling your shoes with sharp objects and trying to walk on them.
Only about one person in ten can use them, and anybody else that can't are looked down on a "wimps'.
Sounds like bad settings on your machine
@@travv88 I tried ALL the settings. I rented the thing for 6 months.
@@roberthunter6927 Ok well there are other machine types. You said you wanted "a machine that follows the normal rhythm of human respiration".
First there is BiPAP which offers different levels of pressure of inhale and exhale.
Then there is ASV, described as "Adaptive servo-ventilation (ASV) machines monitor a person’s breathing while they sleep and deliver customized air pressure to stabilize breathing. The main difference between ASV and CPAP machines is that ASV machines deliver air pressure dynamically, adjusting according to the person’s breathing patterns, whereas CPAP machines deliver a set level of air pressure throughout the night. Each device has specific benefits depending on the type of sleep apnea."
As for masks being uncomfortable. This is true. There are some masks that are better depending if you can breathe through your nose or not.
If you can breathe through your nose look into the Bleep Eclipse which is a maskless solution.
That one is tough to get into Australia at the moment, so if you can't get that there is a new mask I got recently I'm enjoying: Phillips Dreamwear. Much less cumbersome.
@@travv88 Thanks Trav. I will look into it. Yes, Oz is not the best if you want to get something unusual. In the meantime, i have stopped smoking and lost a little weight. It helps a bit.
@@roberthunter6927 That's great. I also quit smoking, and alcohol. I found alcohol really made it worse.
Why doesn't this doctor tell people to change their diet and eat proper human food ?
You can get off your CPAP and remove sleep apnea by eat a clean carnivore diet.