Curcumin: Some should use it, some should not. Which are you?

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  • čas přidán 10. 09. 2024
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    [1] doi:10.3389/fendo.2021.669448
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Komentáře • 268

  • @randallsample1005
    @randallsample1005 Před rokem +23

    I hadn't realized that curcumin helps with blood sugar issues. It would be interesting to learn if its anti-inflammatory properties are truly helpful for cardiac concerns.

  • @edwardanderson1053
    @edwardanderson1053 Před rokem +34

    Curcumin also has anti-carcinogen and anti inflammatory properties for musculature and tendons as well, these are the subjects of several studies.

    • @Maazzzo
      @Maazzzo Před rokem +9

      As someone with multiple inflammatory conditions (fibre, EDS, arthritis) this is what I am interested in when it comes to curcumin.

    • @mindfulmomentswithColm
      @mindfulmomentswithColm Před 8 měsíci +2

      @@Maazzzo if you change your diet you can overcome arthritis and inflammation.

    • @teddybearroosevelt1847
      @teddybearroosevelt1847 Před 7 měsíci

      @@mindfulmomentswithColmYes, definitely. Lots of vegetables and the occasional bit of fruit will do a lot for you to reduce inflammation and many other aspects of the Mediterranean diet will help you greatly. For one thing, stay away from processed food as much as you can and avoid alcohol as well.

    • @petemitchell6788
      @petemitchell6788 Před 3 měsíci +2

      If you’re such an expert, start your own CZcams channel instead of poaching others.

  • @alphatauran
    @alphatauran Před 6 měsíci +19

    You are definitely the best nutritional podcaster I have encountered so far.

    • @DoritoWorldOrder
      @DoritoWorldOrder Před 6 měsíci

      He sounds very confident and convincing to a layperson, but he doesn't actually know what he's talking about on most things, and doesn't really understand how to read study literature.

  • @azalea1404
    @azalea1404 Před 6 měsíci +16

    I suffer from myalgic encephalomyelitis (ME) - a multi-system autoimmune disease. Among the many physical malfunctions ME encompass, neuroinflammation is one of them.
    I experience great improvement by taking 1 teaspoon of curcumin mixed with a teaspoon of freshly grined pepper, and a teaspoon olive oil - all disolved in juice, tea, coffee, or yoghurt naturel. Curcumin does NOT taste good, but it certainly helps on my headaches, fatigue, and cognitive problems.
    Thanks for a great science channel ❤🙏❤

    • @IonidisIX
      @IonidisIX Před 12 minutami

      take the curcumin pills I have talked about, just read my comments :)

  • @oleinkar3933
    @oleinkar3933 Před rokem +14

    I take curcumin supplements regularly to lower my inflammation. I have ankylosing spondilitis, so I get flare ups often. It really helps a lot and I have managed to keep my autoimmune disease under control without biologics. Just using supplements, anti inflammatory diet (avoiding sugar and other triggers) and exercise. Thanks for this video. Im a big fan of your work. Thank you!

    • @pipp33
      @pipp33 Před 6 měsíci

      Would you mind sharing your supplement stack for helping with AS and inflammation?

  • @neilpickup237
    @neilpickup237 Před 4 měsíci +4

    My doctor recommended curcumin to help with some medication side effects.
    I have suffered with migraine since late childhood, although it could be weeks between attacks, they tended to be in clusters leaving me low for a few days without early use of my medication for whenever I had an attack.
    After taking curcumin with success for many months, I noticed that my migraine medication (which I carried in my wallet) was out of date. I then couldn't remember when I last had an attack. I have now been free from debilitating migraines for over a decade.
    Interestingly, the only other period that I was migraine free was while I was on steroid treatment, so I am suspecting that my migraine was, to a degree, related to inflammation.

  • @joyfour4995
    @joyfour4995 Před rokem +25

    Good morning Nic, I love your videos! They are very informative, and so easy to understand. Keep up the good work!

  • @edithh6779
    @edithh6779 Před 11 měsíci +7

    Garry Small ( UCLA, I think,) did a trial to measure the benefits of Theracurmin, a nanoparticle form of curcumin. It was relatively successful in reducing cognitive decline. Granted it was as a small study, but it has found its way into AD prevention protocols.

  • @marcob.7801
    @marcob.7801 Před rokem +10

    Just LOVE ALL your stuff Nic! you are my favorite "physionic" YT channel! You present in an intelligent, concise and digestable (pun intended) fashion and are never pretentious! You sir, are a genuine teacher and seeker of the truth! I've been a subscriber for some months and look forward to all your new content! Thanks and Kudos "professor!"

  • @michelew2191
    @michelew2191 Před rokem +6

    I've never heard of "inflammation genes", that seems interesting. For what it's worth, I've noticed turmeric supplements seem to settle my ibs symptoms, but never did enough experimentation to know for sure. This video doesn't exactly explain that, but I was told I have pre-diabetes around the same time that my ibs symptoms started kicking up...maybe some sort of pancreas/liver/insulin/sugar connection? Really don't know, I just take shots in the dark until I find things that work but videos like these help inspire me and give me ideas on what things to try more or less of. Gonna go back and do more experiments with turmeric now. Ty!

  • @O_Observer
    @O_Observer Před rokem +8

    Guys, dont forget to check your lead levels using hair mineral analysis ( i think the name is metalogram). Currently Im treating lead in my body since it was the main responsible for my kidneys stones and the fact I took turmeric powder for years contributed for this I believe

    • @thomasmuller1850
      @thomasmuller1850 Před rokem

      My vendor for such a test allows to use finger and toe nails too. I have heard, that a hair analysis can be affected by hair conditioners, shampoo etc. So could taking nails be better?
      How do you treat your lead level?

    • @O_Observer
      @O_Observer Před rokem +1

      @@thomasmuller1850 There are some easy procedures to do in order to perform such tests like use neutral shampoos for some time before taking the hair samples. I used Dmsa following the schedule of Acc protocol to remove lead. Im not producing anymore the kidney stones after the treatment. I had to take magnesium with every meal in order to avoid them before

    • @lukaszklopotek
      @lukaszklopotek Před rokem

      I wonder if curcumin extract has the same lead contamination problem as the 1:1 root powder.

  • @peterhoy2382
    @peterhoy2382 Před rokem +3

    Hello again. I had been taking osteo biflex (Glucosamine/Chondroitin) for joint pain (side note: our yellow had unbelievable help when we gave it to her). However, my finger joints started to give me some pain (guitar player, not good). My primary physician (from India) suggested Curcumin. I got some and in a very short amount of time ... no more finger joint pain. I've been taking for several years now ... still no finger joint pain. Btw ... "Normal blood sugar numbers" before starting curcumin. Started Low Carb/Mediterranean ... really good blood sugar number (checking fasting insulin and A1c in addition to the standard fasting glucose number).

    • @aditya7955
      @aditya7955 Před rokem +1

      Whats the curcumin dose you take? I have ankylosing spondylitis and want to try this

  • @jeffreyjohnson7359
    @jeffreyjohnson7359 Před 11 měsíci +3

    Dr. Stanfield actually does recommend for people with osteoarthritis. Lucky me, I have that and t2d...

  • @zanzabar7878
    @zanzabar7878 Před rokem +4

    Just discovered your channel, been binge watching. Fantastic content thank you

  • @spockboy
    @spockboy Před rokem +4

    Excellent videos. Extremely informative, pleasantly explained, you've found your calling son.

    • @Physionic
      @Physionic  Před rokem +1

      Thanks, SB. I’ve seen a few of your comments around. Thanks for watching.

  • @NaturopathTroy
    @NaturopathTroy Před 9 měsíci +2

    Nic- your channel and insights are incredible. Forever grateful. I could literally sit and watch all your videos all day long. Perhaps I am a nerd, too? Thanks man!

  • @tonyprice2256
    @tonyprice2256 Před 6 měsíci +1

    I don't really bother with supplements. I simply add generous amounts of real turmeric and pepper to my foods - usually steamed veggies or ground beef.

  • @vladmirgolobovic518
    @vladmirgolobovic518 Před rokem +5

    Nice video. I think we need to start acknowledging though an inconvenient gap between what the studies say and what happens in clinical practice.
    Curcumin is often touted as this magic anti-inflammatory, and yet we still have people with autoimmune diseases having to go through strong immunosupressants.
    As an alternative therapy, I'd be much more interested in seeing the mechanism of Low Dose Naltrexone (LDN) than Curcumin, which has been gaining a lot of traction, in special now with the Long Covid RCTs. In general, people that seek LDN prescriptions have already tried things like Curcumin and other supposedly anti-inflammatory supplements. This leads me to believe that Curcumin is great in paper, but not so much in practice.

    • @okamsug
      @okamsug Před rokem +1

      It doesn't work on any illnesses that people anecdotally claim to have helped them. I've tried using it for arthritis and heart disease for many months with no improvement.

    • @IonidisIX
      @IonidisIX Před 6 měsíci

      It has helped with my IBS tremendously and I take 20,000mg capsules twice a day. Though from experimentation even 10,000 2x a day would be sufficient. I like the extra protection it offers to my gut pain.

  • @lescoursdefrancaisdemonsie2826

    Thanks a lot for this very interesting free review ! Great video in a smart format 😊

  • @idme8295
    @idme8295 Před 6 měsíci +3

    I read this at first as Circumcision: Some should use it, some should not!"

  • @supernova1976
    @supernova1976 Před rokem +2

    This is very cool indeed . i am a big advocate for turmeric supplementing , i discovered the benefits in fast recovery form colds and any infections, then started researching the anti-inflammatory properties , didn't look into blood sugar effects for some reason it was always being dismissed by Drs :) I wander why 😇. Thank you for sharing .

  • @Galdring
    @Galdring Před 11 měsíci +3

    Great video!
    Do you recommend supplementing, or just eating a bunch of spice? Add fat for increased absorption?

  • @mikegriffin8403
    @mikegriffin8403 Před rokem +2

    Your video focuses on curcumin's effect on blood glucose and diabetes. That is fine & good. But my impression of curcumin/tumeric's primary benefit is that it's an anti-inflammatory. I'm more accustomed to seeing berberine & cinnamon supplements presented for managing blood glucose levels.

    • @Physionic
      @Physionic  Před rokem +3

      I’ll need to dedicate some time to analyzing studies on curcumin and inflammation, then.

    • @eliseville
      @eliseville Před rokem

      @@Physionic Your lecture just gave me more clarity on how it slows inflammation. I am more interested in how it interacts in our microbiome!

  • @inhocsignovinces8061
    @inhocsignovinces8061 Před rokem +3

    The reason I'm personally steering clear of Curcumin as a supplement is that it inhibits P-glycoprotein activity. The same reason applies to piperine, quercetin, and vitamin K2.

    • @xXxXxCGPBxXxXx
      @xXxXxCGPBxXxXx Před rokem +5

      What does this mean in lay terms? I tried to find the answer but didn’t exactly get a sufficient answer. Interested…

    • @Dan-dg9pi
      @Dan-dg9pi Před rokem

      This paper appears to suggest that P-Glycoprotein is a cause of cancer Multidrug resistance. www.ncbi.nlm.nih.gov/pmc/articles/PMC5198046/#:~:text=Curcumin%20as%20Modulator%20of%20P,models%20%5B21%2C33%5D.

    • @Santa-ny1yp
      @Santa-ny1yp Před rokem +1

      @@xXxXxCGPBxXxXx P-gp protects the body from harmful substances by pulling it from the liver and kidneys into the urine and bile. It also helps maintain the blood-brain barrier. Since P-gp molecules are present in many organs like BBB, kidney proximal tubule, and bile ductule, their inhibition can potentially improve not only the absorption, but also the distribution, metabolism, and elimination of their substrates. this is google search so I can't translate. Looks like it has potential positive and negative effects.

    • @eliseville
      @eliseville Před rokem +1

      Hindus who have been traditionally non-meat-eaters, have used turmeric dietarily in their daily curries and counteracted the diabetes their more carbaceous diets otherwise would have produced.
      They also got plenty of MK7 (K2’s calcium-directing form) from their many fermented pickle varieties🎉
      I doubt many turned down curry or chutney because of P-glycoprotein worries.

    • @luckerooni1153
      @luckerooni1153 Před 14 dny

      Vitamin K2? So Eggs?

  • @martinlang9615
    @martinlang9615 Před rokem +1

    I was pre diabetic prior to starting Carnivore (actually Lion “diet”…hate that word, really it’s a lifestyle). It’s been 2.5 months no longer pre diabetic. My CRP is low, but I would like it lower. I already have plenty Curcumin in a powder form with absorption agent, so I will start it again.
    I’m a chronic pain suffer, so anything to keep my inflammation low is a good thing.
    Apart from not being prediabetic I no longer have high blood pressure, sleep apnea.
    Love your videos. I’m a new Sub.

  • @sharonkende4774
    @sharonkende4774 Před rokem +1

    How cool (and informative) is this video? Wow, kudos. Great explanation of how curcumen works

  • @PeterTea
    @PeterTea Před rokem +5

    Thanks! I guess as a type 1 diabetic I should keep taking my tumeric supplements. Is it important to take it with pepper? I remember that you mentioned in another video that pipian (not sure if that’s the right term) from pepper increases the absorption of curcumin substantially.

    • @Physionic
      @Physionic  Před rokem +3

      Yes, Peter - good memory!

    • @eliseville
      @eliseville Před rokem +1

      Yep! But along with “piperine”which makes many substances (including my anti-seizure med carbamazepine) more bioavailable, fats help too. That’s why a warm & definitely fatty peppered “golden milk” is so powerful💪
      (For Keto I make it with Milkadamia, MCT, pepper, turmeric, ginger, Ceylon cinnamon & cardamom, usually sweetened with Allulose. Yum! Coconut milk would work very well too, but has higher carbs to count.)

  • @gl4thpgmail702
    @gl4thpgmail702 Před rokem +1

    In what form do we take curcumin…do we just start putting turmeric spice and pepper on everything we eat? How much should we take? How often? Can someone help me to understand how to use this. Thank you in advance. ❤

  • @patmay1689
    @patmay1689 Před rokem +4

    Can you maximize muscle growth with 16:8 intermittent fasting? Sorry it's not in line on what you are talking about today

    • @eliseville
      @eliseville Před rokem +1

      Pat, extended fasting will also waste muscle, though 16:8 is generally too short. Muscle “building” requires weights & higher protein. The intermittent fasting, itself, only protects muscle in comparison to other weight loss methods.

  • @barbarashirland9078
    @barbarashirland9078 Před rokem +1

    Thank you. Always appreciate your research based info.

  • @pong4life
    @pong4life Před rokem +1

    I just started curcumin since studies have shown it can help with inflammation and muscle recovery. I will know soon weather that works on me or not. Dr Stanfield is more interested in life extension, not muscle recovery. It's nice to know curcumin can also help with blood sugar.

  • @DM-jt4rh
    @DM-jt4rh Před rokem +2

    This is one of THE best scientific breakdown / bio hacking channels out there imho.

  • @DBMMMMM
    @DBMMMMM Před rokem +1

    I had years lasting inflammations as result from heavy bruxism. Once in a while I had to use antibiotics, the inflammations lasted at least 20 years. Until the moments I started pressing my own 1000mg caps Kurkuma+pepper in 10:1..20:1 ratio, used 3000mg daily for half a year or so, in just 1 week the inflammations were gone and never returned.
    My dentist could not understand why it worked but it DID

  • @outriding
    @outriding Před 11 měsíci +1

    Thanks for the information you present.

  • @idragonfly
    @idragonfly Před 6 měsíci

    I've been diagnosed with ME/CFS and have been taking Turmeric (with Piperine) to help curb the chronic inflammation that this condition tends to generate.
    My question is ... would Turmeric (with Piperine) be as effective as Curcumin - in this particular scenario?
    And ... Does Curcumin require Piperine for absorption - as well?

  • @adm129100
    @adm129100 Před rokem +1

    Hope you do another video on curcumin as a painkiller / cox-2 inhibitor

  • @mbustube1
    @mbustube1 Před rokem +3

    Driving me crazy trying to figure out who this young man reminds me of. Hazard of old age--everybody looks familiar.
    Great content.

    • @bp56789
      @bp56789 Před rokem

      3brown1blue?

    • @LoveLove-qm6ye
      @LoveLove-qm6ye Před rokem

      A young Clark Kent

    • @mbustube1
      @mbustube1 Před 10 měsíci

      He looks like my nephew. I'm 67 years-old and have this problem as well. Everybody looks familiar.

  • @LifeWithRilla
    @LifeWithRilla Před rokem +2

    I'm considering doing an extended water fast. I'm first going to go speak with my doctor & start documenting and posting about the results & how I feel. It would be great to watch videos you make on how things progress for me. The extra layer of accountability from another CZcams would definitely aid in motivation!

    • @eliseville
      @eliseville Před rokem

      I think non-scientist “nutritional science guru” Tom DeLauer covers a study showing curcumin powerfully instigating early autophagy.💪

    • @martinlang9615
      @martinlang9615 Před rokem

      Did you see the 31st July video on water fasting?
      Good luck (maybe you have already done it by now).

    • @hometown1474
      @hometown1474 Před 7 měsíci

      Your doctor will crap on the idea, guaranteed.

  • @Vogeln
    @Vogeln Před rokem +5

    Thanks for a very interesting and thought-provoking video. Question: Is curcumin the only beneficial compound in turmeric? In addition to it's anti inflammatory and and anti diabetic properties, I've also read that turmeric has some neuro-protective and anti-cancer ones as well. Is there any truth to this and if so, can they all be attributed to curcumin alone or are there other compounds in turmeric that could be responsible?

    • @Physionic
      @Physionic  Před rokem +3

      It's the main compound, but it's still possible other compounds could also be of benefit. I would probably focus on curcumin, however. I haven't looked into those areas myself, yet, but I can tell you that I've read similar claims in the scientific reviews.

    • @anne9134
      @anne9134 Před rokem +3

      So can you please look into brain inflammation.

    • @dailyoccasions9539
      @dailyoccasions9539 Před rokem

      Will it help with Multiple Sclerosis?

    • @jamescalifornia2964
      @jamescalifornia2964 Před rokem +2

      ​@Anne 😮 Lately, it seems everyone's brain is inflamed !,

    • @eliseville
      @eliseville Před rokem

      @@dailyoccasions9539 Any healthy anti-inflammatory will help you. But please research how high HORMONE D LEVELS can put MS into remission!!! Other necessary treatments are also combined. There’s an original Brazilian high D protocol & some in the US have been very successful, too (sorry I cannot remember their names, but should come up in a search💔)

  • @sylviaanderson704
    @sylviaanderson704 Před rokem

    So happy to have found your You tubeI I liked and hit the bell,I was happy to hear about your info on curcumin

  • @littlevoice_11
    @littlevoice_11 Před rokem +3

    Do you worry about the oxalate amount?

  • @anerexicpig720
    @anerexicpig720 Před rokem +2

    Im not pre diabetic and decently healthy, and i can get 90 caps (3 months worth) of curcumin for about 7-8 dollars. Just for the reduction of inflammation it seems like a good deal

    • @eliseville
      @eliseville Před rokem

      If it prevents the diabetes we are ALL being pushed towards, it is the very best investment!

  • @jeffhutjens
    @jeffhutjens Před rokem

    Apart from NFkB, curcumin also suppresses microglial and glutamate excitotoxixcity, very relevant in chronic pain.

  • @coisalinda2424
    @coisalinda2424 Před 12 dny

    I just understood the connection that you made between turmeric Kermit and macaroni. The rest I missed.

  • @the3cl3ctic
    @the3cl3ctic Před 10 měsíci +1

    Can you get the effect by taking powdered curcumin or is it better to take it fresh?

  • @indridcold4210
    @indridcold4210 Před 9 měsíci

    I'd love to see a study on people who had pre-diabetic levels of blood sugar who also took a reasonable amount of berberine. It seems that if the effects were additive, then the combination could extend a lot of lives. High A1C levels are directly related to CVD complications such as heart attacks, strokes, and CHF

  • @grainiac7824
    @grainiac7824 Před 4 měsíci

    My husband paid no mind to my efforts to manage my insulin resistance until his arthritic thumbs were killing him and I suggested he try it. He seemed sheepish as he acknowledged it worked

  • @keithbertschin1213
    @keithbertschin1213 Před rokem

    Great video, no hyperbole, many thanks

  • @RCV2024
    @RCV2024 Před rokem

    Eagerly looking forward to your carnivore eval video to drop 🔥

  • @renatap.6100
    @renatap.6100 Před měsícem

    I've heard that curcumin is one of PAINS (pan-assay interference compound) and IMPs (invalid metabolic panaceas)...

  • @IonidisIX
    @IonidisIX Před 6 měsíci

    IBS sufferer here. Hands down the best natural remedy I came across in my journey towards health is curcumin. I have been taking 20,000mg twice a day for the last 3-4 years and I can safely say, that it has no adverse effects (not that I am aware at least) and it has definitely helped with my gut inflammation issues. Thank God I came across this substance a few years ago because aging does not help with IBS (not to mention other auto-immune disorders).

    • @KiIlAllMen
      @KiIlAllMen Před 4 měsíci

      Which formulation are you taking now?

    • @IonidisIX
      @IonidisIX Před 4 měsíci

      @@KiIlAllMen The same. I have also found butyric acid to be very helpful as well. So curcumin and butyric acid are the best out there (for my type of IBS at least).

    • @joelsombroek
      @joelsombroek Před 27 minutami

      40 grams a day ???

    • @IonidisIX
      @IonidisIX Před 13 minutami

      @@joelsombroek it is the chemical equivalent, it is only 2 pills per day every 12 hours, with both having enough curcumin corresponding to 40 grams of turmeric. I've been doing this successfully for 6-7 years at least. So any concern anyone raises about a potential toxicity of this natural remedy, I would simply disregard it or take it with a big pinch of salt. This substance is truly the most potent non-chemical non-drug anti-inflammatory I have known, the next best is Mesulid, but that is a proper drug which I take in special/difficult circumstances regarding my IBS flare-ups. BTW, after so many years with this problem I find that the biggest culprit is not carbs, not sugar but definitely crappy oils like rancid vegetable oils (sunflower, safflower, canola, etc) and especially palm oil. Palm oil is hands down the most pro inflammatory vegetable oil out there and the food industry has it literally on every piece of junk processed food out there. People read the labels!

  • @birage9885
    @birage9885 Před rokem +5

    Stanfield is off on many things, and even admits it. Curcumin can bind or block iron in the body, good for most people, since iron is a problem for most people, however, there are people who have iron dysregulation or deficiency issues. This form was studied to not block iron absorption.
    www.ncbi.nlm.nih.gov/pmc/articles/PMC8308323/

    • @tomthecat8172
      @tomthecat8172 Před rokem +1

      OH MY GOD, I had no idea there was a connection between curcumin and iron. My mom is anemic and her red blood cell counts have been steadily decreasing. Now that I look back on it, it coincides with her taking turmeric daily in the mornings but never in a million years would I have pegged it as a potential suspect.
      I'll have her stop and see if her bloodwork improves in a few weeks. Thank you for this!!

    • @SalfRaettele
      @SalfRaettele Před rokem +1

      ​@@tomthecat8172Do you have an update?

  • @bryanstanley4295
    @bryanstanley4295 Před 4 měsíci

    But it should still provide antinflammatory and antioxidant benefits for all people correct?

  • @cityinthesky1341
    @cityinthesky1341 Před 2 měsíci

    Cumin, not curcumin, when added to a cup of ramen noodle soup is heaven for your taste buds. Someone should figure out a way to make a healthy version of a ramen noodle soup cup. When you think about how easy it would be add your favorite spices to it, this could have a significant impact on the lives of many.

  • @GiorgiGioshvili
    @GiorgiGioshvili Před 2 měsíci

    Is there any study comparing cooked tumeric vs. powder vs. supplements?

  • @coisalinda2424
    @coisalinda2424 Před 12 dny

    Maybe the reason is because I didn’t graduate from high school what do you think?

  • @corpusarmatae8541
    @corpusarmatae8541 Před rokem +1

    The conclusion made me curious. Has there ever been a nutrient/supplement shown to be a good alternative to medication, actually ? I can't think of any whatsoever.

    • @ps7797
      @ps7797 Před 6 měsíci

      I know I'm not answering your question strictly speaking (like a 1 for 1 swap of curcumin for metformin), but there are examples where meds might be eliminated in lieu of non-phamaceuticals. Exercise has tremendous anti-depressant effects over many drug treatments. Or changing what you eat reversing some metabolic disease when the meds are only managing symptoms. (I'm not against meds, but they aren't the only answer... Though sometimes they may be). I'd rather take turmeric instead of ibuprofen. But if the pain is bad enough, I'll take it or acetaminophen.

  • @dougprentice1363
    @dougprentice1363 Před 3 měsíci

    Ive had kidney stones. I know tumeric is high oxilate. Is curcumin suppliment high? I can't find any info.

  • @czarcoma
    @czarcoma Před 2 měsíci

    I am still trying to wrap my head around what inflammation is at the cellular and molecular level. My solid idea for inflammation is still "i banged a part of my body somewhere" or "certain of my glands are infected" and some parts of body is swollen beyond normal.

  • @lk6789
    @lk6789 Před rokem +1

    I don't take as a supplement but I do use it quite a bit in cooking, My Dna says I am insulin resistant, but I have no signs of diabetes. My mother and her mother were both diabetics, not due to being over weight, insulin users. Should I take as a supplement, or am I getting sufficient in my diet (BM 20)

    • @eliseville
      @eliseville Před rokem

      Eating patterns are inherited far more than diabetes, itself. Diabetes can take decades to develop from its low D/Insulin Resistance beginnings, so if you eat like they do, turmeric could be a very potent protective!

    • @lk6789
      @lk6789 Před rokem

      @@eliseville As they both followed a diabetic diet and were the main cooks then my diet if inherited should be good. I do have an healthy diet, no package, fast food, processed food, all fresh , no alcohol and never smoked just like them, but they still had diabetes and non of us is/was overweight. Diet may help but I think genetics takes precedence.

  • @neuromax3766
    @neuromax3766 Před 8 měsíci

    I started taking Curcumin 5 years ago. I was having problems with short term memory and a young man I knew said that his dad, who was the head of psychiatry at a big university hospital, was involved in a study of curcumin for short term memory that was showing good results. I started taking it and within 2 weeks my short term memory was noticeably better and still is. I'm not going to talk about the effect on my erections so - don't ask.

  • @davidfeldmann7497
    @davidfeldmann7497 Před 4 měsíci

    Do these pathways you discussed explain why it usually helps with tonsil stones that I experience when I feel low energy?
    I still don't get who should not take it

  • @jakehayes1345
    @jakehayes1345 Před rokem

    Great video! Now I feel even better taking Curcumin (Turmeric)
    great channel, I'm glad I found it. 😎

    • @Physionic
      @Physionic  Před rokem +1

      Thanks, Jake! I didn't see your other comment.

  • @jodimichelleschoenherr
    @jodimichelleschoenherr Před 6 měsíci +1

    ✝️ We love it. Great ❤ work 📰 News Show

  • @leondevries478
    @leondevries478 Před rokem +1

    Wow very interesting information. I read that IL-6 is (for a big part) responsible for the feeling of fatigue while having for example the flu. Should turmeric/curcumin therefore help for people with CFS ? Very curious, thanks an best to you from the Netherlands…

  • @tabithawolf1
    @tabithawolf1 Před 8 měsíci

    “900%”
    Hahahaha! You got me! Curcumin went everywhere. I’m still getting it out of my keyboard.

  • @DalyD
    @DalyD Před rokem

    I hurt my back years ago due to a herniated disc and I am currently going through a flare-up. I am doing a number of things to get better, but I've been taking a curcumin (with piperine!) supplement daily to reduce inflammation in my sciatic nerve. I don't think it has made a dent in pain levels, but I'll continue going through the whole bottle in case the anti-inflammatory effects compound and help me get back to a pain-free state quicker. Diabetes also runs in my family though, so as I get older, I'll definitely keep a close eye on this one. Hopefully by the time I'm getting into late middle age these supplements are cheaper!

  • @Marc_de_Car
    @Marc_de_Car Před rokem

    Thanks

  • @robertsmyk4102
    @robertsmyk4102 Před rokem

    Elevated blood sugar is not the problem, persistent elevated blood insulin levels is the problem and so it would be interesting to know how curcumin affects the release of insulin and what is the mechanism.

  • @griffin2599
    @griffin2599 Před 5 měsíci

    What do you think about turmeric/curcumin causing liver toxicity? I feel like you would have to take an excessive amount to do that. Maybe 10,000 mg plus ?

  • @HarryHound
    @HarryHound Před 16 dny +1

    HPV cancer p53

  • @jodimichelleschoenherr
    @jodimichelleschoenherr Před 6 měsíci +1

    Question 🙋🏼‍♀️
    Do you like your gift 🎁 ❤❤❤😂😂😂❤😜🧐🤓🥸

  • @rhombifer566
    @rhombifer566 Před 3 měsíci

    What about all the other information you said that it does for health benefits besides what you're talking about now?

  • @fifouyamina8238
    @fifouyamina8238 Před rokem

    كنت استيقظ لتبول ليلا لكن بعد شرب مشروب الكركم كل ليلة لا استيقظ الا مع الصباح واذان الفجر أنه رائعا حقا

  • @maxcarter3413
    @maxcarter3413 Před 6 měsíci +1

    If curcumin increases insulin sensitivity then it should reduce C peptide meaning less stress from insulin production and possibly weight loss and reducing the risk of diabetes further in so-called healthy people. In other words, consider the impact of curcumin on the HOMA IR score before you conclude that healthy people see no benefit.

  • @saliksayyar9793
    @saliksayyar9793 Před 11 měsíci

    It also stimulates glucose transporters in beta cells forcing increased secretion of insulin, the kind noted in sulphonylureas. Damaging to the beta cells.

  • @stevencraigbryan3770
    @stevencraigbryan3770 Před 11 měsíci

    I use it and love it.
    I also like
    Glucosamine and MSM at 4gms daily which works best for me. What are your thoughts?

  • @MrMikkyn
    @MrMikkyn Před rokem

    I’ve got ankylosing spondylitis and I want to know why coffee and black tea help alleviate my back pain?
    I’ve read about how caffeine is bad and good in various ways, and how some people avoid it. I find it actually helps me, every time I drink it. I’m not sure what’s happening on the cellular level.
    I know COX-2, TNF, IL17, IL22 are involved in the inflammation.
    I also notice that cherry juice helps. I don’t know what’s going on there. Placebo? Anthyocyanins? No idea.
    I take Meloxicam sometimes in the evening if the pain persists, but I prefer a daily coffee in the morning, as the meloxicam has side effects like upset stomach and diarrhoea.

  • @cheriseelliott9230
    @cheriseelliott9230 Před rokem

    Great job! 👍🏼

  • @DM-jt4rh
    @DM-jt4rh Před rokem

    All participants were instructed to take three capsules with blinded labels of either curcumin or placebo twice a day (total of six capsules per day) for 9 months continuously. Each curcumin capsule has curcuminoid content of 250 mg.

  • @michaelmappin1830
    @michaelmappin1830 Před rokem

    Ty❤

  • @sabincioflec8413
    @sabincioflec8413 Před rokem +1

    It's very good when you are hangover, uhm...a friend told me that, i know alcohol is bad for you. Do you know what the normal dose should be and if more is better?

  • @wturber
    @wturber Před 7 měsíci

    I routinely test on the high side of normal for fasting blood sugar (95-105 typically). Type II diabetes runs in my family. I get a lot of exercise and my blood sugar hasn't gotten any worse in five years. Nonetheless, I still am mildly concerned. So I did some checking on curcumin. What I've found is that I can routinely see my morning fasting glucose drop by about 10 mg/dL about an hour after taking curcumin and some black pepper. Yes, I just grind some up fresh and take it with the pill. An hour later, my glucose will be about 10 units lower. I've also tested an hour later multiple times with no curcumin and see no similar pattern of blood sugar dropping. There has been, however, one exception out of about 7 tests so far where my blood sugar did not drop after taking curcumin.
    Given that Metformin has real side effects (maybe reduces some of the beneficial effects of exercise and inhibit skeletal muscle gains) I'd like to avoid the medication. So maybe @Physionic is on the right track. This may very well be a good supplement for borderline/borderline people like myself.

  • @magncity1817
    @magncity1817 Před 4 měsíci

    You didn’t mention if those pre-diabetics that had 0% progression to Diabetes also had to take pepper with their curcumin. Since you had another vid on the pepper connection it seemed a huge blind site.

  • @swissantiqueradios
    @swissantiqueradios Před rokem

    I believe curcumin is a substance that deserves further investigation. Online there are several studies attesting to its benefits for relieving arthritis symptoms, going so far as to equate its results with the use of nonsteroidal anti-inflammatory drugs.
    For example, my wife started taking curcumin 3 months ago and her pains have reduced considerably.
    Unfortunately, there is not much money to do research on curcumin, I'm afraid the patents have expired.... 😅😅
    Thank you for your science education work.

  • @alexanderishere1857
    @alexanderishere1857 Před 6 měsíci

    What Dr Stanfield and also these videos never discuss though.... is the dosage of curcumin?

  • @polyrhythmm
    @polyrhythmm Před 6 měsíci

    Do you think pepper and curcumin could be a good treatment for fibromyalgia?

  • @littlevoice_11
    @littlevoice_11 Před rokem +1

    I wonder if there is a synergistic effect of having the curcumin in the wholefood turmeric form rather than isolated curcumin?

    • @eliseville
      @eliseville Před rokem

      Turmeric has multiple constituents. Curcumin gets most of the cred, but I also believe the total complex is more helpful.

  • @darrenbraynard4005
    @darrenbraynard4005 Před rokem +1

    Dank music at the end, btw. Question: Could this inhibit beneficial inflammation?

    • @Physionic
      @Physionic  Před rokem +1

      Great question, and yes, Darren. It can.

  • @trevorumback7602
    @trevorumback7602 Před 6 měsíci

    Much cooler than 900% man my hopes plummeted, wiz guy hay 😅😂

  • @danos5181
    @danos5181 Před 9 měsíci

    Does Curcumin have benefits for longevity (regardless of diabetes improvements)?

  • @jamescalifornia2964
    @jamescalifornia2964 Před rokem

    Take with black pepper 😊👌

  • @grantlawrence611
    @grantlawrence611 Před 6 měsíci

    That was funny...900 percent

  • @ChrisMac00
    @ChrisMac00 Před 4 měsíci

    Have you seen studies of thyroid cancer survivors that gone from type 2 to type 1 diabetes in 40s

  • @sleeplessforawhile
    @sleeplessforawhile Před rokem

    Thx so much for sharing with all of us your work and your down->top view. By the way... could you consider to do some videos about more "popular" supplements on "cancer" scenarios? ... yes .. I know... it´s a complex scenario to dive on, but... it coud be so interesting to see that under your "analitic" point of view.

    • @Physionic
      @Physionic  Před rokem +1

      I'm thrilled to do it!

    • @sleeplessforawhile
      @sleeplessforawhile Před rokem

      @@Physionic I´m pretty sure that there will be a lot of people thrilled to watch that... A realistic (not necessarily good or bad) point of view is always necessary. Thank you... once again.

  • @grainiac7824
    @grainiac7824 Před 4 měsíci

    Did he give recommendation on dosage?

  • @mats8038
    @mats8038 Před 11 měsíci

    I take some Tumeric evry day a table spoon in my lemon drink with some garlik and oliv oil and blackpepper( lowered my blod pressure) it do not do anything for my bloodsugar levels they are the same, Normal, but it does help with two fingers on right hand. If i stop taking it i get some pain back in them and i have stopped many times mostly because Tumeric taste like shit so i skip it and then after a couple of days i get pain back in my two fingers. My wife however have another response She have twice as high bloodsugar levels as me normally but they go down to be the same as mine when she takes it. I got her some berberine a couple of weeks ago and she is of Tumeric will check Her blood sugar and see if it works as said.

  • @Galdring
    @Galdring Před 11 měsíci

    A 5-10% drop in total blood sugar is a very large percentage drop in the extra blood sugar a diabetic has. Say your fasting blood sugar is 110, meaning you are glucose impaired before you take curcumin. After curcumin, your blood sugar is 100. Congratulations, you are now in the healthy range! Even if you are diabetic at 125, you're 40% closer to a healthy glucose level.
    That is massive?

  • @mysterio1336
    @mysterio1336 Před 8 měsíci

    is it recommended to take pills or better powder with food? and how much intake? thank you

    • @moomin7461
      @moomin7461 Před 7 měsíci

      If you take pills, it depends on the formula, as some are more absorbable than others. Generally speaking, you're looking at one or two capsules per day.

  • @TheMoicani
    @TheMoicani Před 6 měsíci

    Interesting.