Mid-Afternoon Masterclass: Cloning the Thylacine

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  • čas přidán 6. 01. 2021
  • How do you sequence the genome of the extinct Tasmanian Tiger? And can you use this to bring it back to life?
    Join Professor Andrew Pask in this exciting short lecture as he describes the process of sequencing the extinct Thylacine (Tasmanian Tiger) genome.
    Recorded 17 August 2020 as part of the University of Melbourne's Science Festival. festival.science.unimelb.edu.au

Komentáře • 93

  • @Sawrattan
    @Sawrattan Před 3 lety +14

    Good luck to Professor Pask, very inspiring to see how passionate he is about marsupials and trying to repair our past mistakes.

  • @GriffinWulf
    @GriffinWulf Před 3 lety +7

    I had no idea just how much progress these guys have done! since high school I've fantasizing about the concept of artificial genetic diversity being engineered into animals, i thought it was mostly science fiction. thanks for proving me wrong

  • @anthonyranzie4630
    @anthonyranzie4630 Před 3 lety +16

    Make one soon I would love to see one

  • @phillise1
    @phillise1 Před 3 lety +12

    First time I knew that numbats and thylacines were realted. One evolved to scurry about eating termites, and the other evolved into a coyote -sized predator to hunt kangaroos.

    • @Sawrattan
      @Sawrattan Před 3 lety +2

      Fascinating, first time I learnt this too. For some reason I always assumed tasmanian devils were the thylacine's closest relative.

    • @badmonkey2222
      @badmonkey2222 Před 2 lety +1

      @@Sawrattandevils supossedly only relative so this is news to me as well.

  • @lilimps8135
    @lilimps8135 Před 3 lety +11

    The tasmania tiger is my favorite animal what hes doing will chang the world.

  • @persephonemaeve2704
    @persephonemaeve2704 Před 3 lety +11

    It would make my whole life seeing it cloned. The preserved pup is just the cutest thing. It makes me so sad though when I see it.

  • @simonburke8341
    @simonburke8341 Před 2 lety +6

    I’m so glad I watched this!
    It was such an honest and open discussion about what could happen in the near future!!
    Good luck with your research 👍

    • @jimquantic
      @jimquantic Před rokem

      Don't know if "near" future is correct, hope so

  • @danb340
    @danb340 Před 3 lety +5

    Might not have to go to all the trouble of cloning one watch part 2 of animal x classic s1 at 2:46 on video it's a real one someone filmed in Queensland the southern part I believe, put it on a big screen and watch it's a definite thylacine...

  • @lindamclean8809
    @lindamclean8809 Před 3 lety +1

    Bravo. Thank you so very much for your work and insight

  • @connectwithyourdeck
    @connectwithyourdeck Před 2 lety +1

    Thank you so much for this talk - so fabulous!

  • @mikah9289
    @mikah9289 Před rokem

    I came to this video to get more explanations of what is missing to create the embryo of an extint animal. It seems that we are still missing more time and efforts for that, but now I am not sure anymore if future success could bring solutions, meaningless results, or frightening possibilities for future projects.

  • @josephvasquez6390
    @josephvasquez6390 Před 2 lety +3

    I consider this like healing a wound not cloning

  • @notsosilentmajority1
    @notsosilentmajority1 Před 2 lety +9

    Well done. Excellent video and extremely educational. You held our attention for the entire production and left us wanting more information. Would a return of the Thylacine be a help in combatting the damage being done by invasive species like rabbits and feral cats in Australia and surrounding areas ?

    • @kellysouter4381
      @kellysouter4381 Před 2 lety +1

      Surely they would eat rabbits? That would help.

  • @frednewman209
    @frednewman209 Před 3 lety +3

    This is hope. Sounds great.

  • @PipeCat1965
    @PipeCat1965 Před 3 lety +3

    Is the preserved pup going to last long enough for the technology to catch up?

  • @soul-candii3184
    @soul-candii3184 Před rokem

    Awesome video. Made me incredibly excited seeing as I’ve always wanted to get into this field because of thylacines. Can’t help but get annoyed with how often he’d just cut her off. Like damn, let her finish lol

  • @frednewman209
    @frednewman209 Před 3 lety +3

    Why do you confuse Loxodonta with Elephas, at 22:00 ?

  • @oswaldcannon9483
    @oswaldcannon9483 Před rokem

    Definitely agree with the quote that causing the extinction was playing god. Good luck on the work!

  • @timothyjones8858
    @timothyjones8858 Před 3 lety +2

    I would love to see them.

  • @rodneyjensen5148
    @rodneyjensen5148 Před 2 lety +1

    I am so impressed with your research. Can you explain a little more about the blue areas in DNA strands?

  • @AussieAquatic
    @AussieAquatic Před 3 lety +2

    Fascinating 🤔

  • @marklarson4251
    @marklarson4251 Před 3 lety +2

    I like the thylacine.

  • @TrekkinTales
    @TrekkinTales Před 3 lety +4

    There is picture of an African elephant that is labeled as Asian elephant.

  • @herpdiversity9152
    @herpdiversity9152 Před 3 lety +1

    Wow. I hope this works well.

  • @Evan102030
    @Evan102030 Před 2 lety +5

    How do you engineer enough genetic diversity to prevent inbreeding and maintain a healthy breeding population? This lack of diversity was seemingly already an issue when they were still around.

    • @jimquantic
      @jimquantic Před rokem +1

      I can't recall the particulars, but I read a few years ago, that biology has a mechanism which comes into play when a population is extremely small--to prevent extinction of the species. But only ONE? Who knows, but I would think their initial production would result in at least a small group with some diversity.

  • @LostFelidae
    @LostFelidae Před 3 lety +4

    Regarding the size and genetic differences with the Numbat, are there possibilities to use an artificial womb for the first few specimens instead of surrogate species?

    • @yerman0564
      @yerman0564 Před 3 lety +5

      That's what I was thinking.
      Since marsupials are born so small, I wonder if they could use a devil, quoll, or as you say, a numbat.

    • @ToeIn2194
      @ToeIn2194 Před rokem

      To my understanding as a biology student artificial wombs are not usable for early pregnancy yet, only maybe late pregnancy as seen with some farm animal that was grown in an artificial womb that looked like a bag. So far...

  • @allenarnold6804
    @allenarnold6804 Před 3 lety +1

    👏🏼👏🏼👏🏼👏🏼👏🏼👏🏼

  • @korrupptteddkat1515
    @korrupptteddkat1515 Před 2 lety +3

    Im curious to know what would become of the first de-extincted thylacines if it were to occur? I doubt that they would engineer a male and female and then just release them into the Tasmanian wilderness. At what point would a thylacine population be bred to in captivity and then reintroduced? There is also the question of reintroducing captive animals into the wild, and their ability to be able to learn behaviours that they would require to survive.

    • @sibellakingston52
      @sibellakingston52 Před 2 lety +1

      *Australian* wilderness. They weren't just in Tasmania.

    • @jimquantic
      @jimquantic Před rokem

      @@sibellakingston52 same question still applies--when/how?

  • @afwalker1921
    @afwalker1921 Před rokem

    I want one!

  • @dovets
    @dovets Před 3 lety +8

    How will the individual variance/ diversity be catered to from using just this one source. It may produce one animal, but multiple from this one DNA would not produce a viable breeding population would it. In other words, using only this one source would provide a single animal multiple times, thereby creating the problems of inbreeding, would it not?

  • @shanelepse4402
    @shanelepse4402 Před 2 lety +1

    Expedition to west Papua highlands thylacine still roam around there

  • @davidsimpson3275
    @davidsimpson3275 Před rokem

    They have been Seen on the Outskirts of Melbourne , Upper Beacons Field ,...
    Tough , Country Rocks , Blackberries , know One knows what's in that Bush...

  • @robritoboy
    @robritoboy Před 3 lety +1

    They look a little bit like a dingo. Is there any way they could have interbred? If their common ancestor is so long ago, probably not, but just interesting that they sort of have the same look in a way. Maybe you could compare and see if they share something.

    • @barbeeska
      @barbeeska Před 2 lety +1

      No. They are an example of convergent evolution whereby animals can end up looking similar and occupying similar niches biologically without being genetically related. In fact the thylacine is believed to have functioned more like a feline than a canine. As a marsupial the thylacine carried it's young in a pouch (I think). And while it was usually on four legs it could also hop like a Kangaroo.
      A truly unique animal. 💔

  • @bigfellasydney6970
    @bigfellasydney6970 Před 3 lety

    Is this project affiliated with Prof. Mike Archer's work?

  • @franktuckwell196
    @franktuckwell196 Před 2 lety +1

    This is fascinating stuff, but your big advantage is actually having thylacine on film, whereas the yowie is as elusive as the bigfoot. Sightings but no proof, i.e. a body to study. I for one shall keep watching.

  • @016162877
    @016162877 Před 2 lety +2

    I don't know what all the fuss is about... They already did it for Jurassic Park....... 😜

  • @jimquantic
    @jimquantic Před rokem

    Anything from 2022? Second, any thought of using closely related species in some way to cross breed with yet another species and bring back--not the thylacine, but something akin?

  • @davida.4933
    @davida.4933 Před 3 lety +9

    The real controversy is whether the thylacine is extinct. It may also be more accurate to blame farming vs. "hunting" for the demise of the thylacine.

    • @benjaminclarke7984
      @benjaminclarke7984 Před 3 lety +4

      It's extinct. There's no hard evidence, just pages of people who think they've seen it.

    • @joedorben3504
      @joedorben3504 Před 3 lety +2

      It's not a controversy. Not in 2021

    • @mattk9089
      @mattk9089 Před 2 lety

      I don't think it is controversial to call it extinct at this point. The 'sightings' industry is just that until there is 100 percent proof found that it still exists. There have been plenty of 'Elvis' sightings also! And it was because of farming that the bounty was put on the animal. So it was for both of those reasons that made it extinct.

    • @mickbrown4855
      @mickbrown4855 Před rokem

      It may or may not be extinct in Australia but I have worked in Papua New Guinea for 25 years & the locals there tell me that the villagers in the southern parts (just to the north of the Torres Straits) often have problems with these killing their livestock. Makes sense that some of the fauna from Australia exist just on the other side of the shallow straits. Would be a lot easier to capture a few from PNG & establish a breeding population in Australia.

    • @davida.4933
      @davida.4933 Před rokem

      @@mattk9089 I agree it was largely because of farming (and not "hunting" per se) - maybe that distinction is lost on many people. And there is no "sightings" industry, just thousands of people who claim they have seen thylacines post 1936. The analogy to Elvis sightings is always good for a laugh, but there was one Elvis and we know for a fact he died. We don't know for a fact the last thylacine died in 1936, and it's improbable that was really the last one. I find most people who are so convinced the thylacine is long gone have never really met those who have had very believable sightings. Well, I have and it makes an impression upon you when you sit across the kitchen table from these people and spend time with them and it's pretty obvious they are not only sincere but that their sighting was - in many cases - extremely strong and not just some running distant animal dashing across the road at night for a split second. Most of the critics have never even been to Tasmania or met anyone who has a sighting. Meet a dozen or so people who have had strong sightings and I'll bet you start to doubt your own view they are long gone. By the way, I am a biologist by training and I don't want to sound like I'm 100% certain they are still extant. I do lean toward the conclusion they are difficult to document and rare.

  • @Innaturesrealm
    @Innaturesrealm Před rokem +1

    The Thylacine is not extinct its numbers dropped to a very low level but there populations are building up again. Hans Harding a fisheries officer had the best and undisputed sighting back in 1985. Yes thats right 1985 less than 50 years ago. Lets put our efforts into protecting these beautiful animals habitat then trying to bring back something thats just a fancy dream and wont work.

  • @flugschulerfluglehrer7139

    Please clone a Dodo. I desperately want a pet Dodo!

    • @therealyt5725
      @therealyt5725 Před 2 lety +2

      I wanted to see a Dodo my whole 41 years of life. From what I hear they were some beautiful looking birds to see.

    • @TheGamingCapybara
      @TheGamingCapybara Před rokem

      @@therealyt5725 the dodo had over 2000 diseases so it would prob be a bad idea. i looked it up from a article that was part of a book on the dodo

  • @VidAudioJojo
    @VidAudioJojo Před rokem

    Wrong photo at 23:00. Photo shows an African elephant instead of an Asian elephant.

  • @DrFlippin
    @DrFlippin Před 3 lety +2

    Wouldn't it be easier to take any abandoned, beige-coloured mongrel with a triangular head, and paint some black tiger stripes on it's hind end? Lol. Don't know what to do about a pouch, though...

  • @michaelgully4630
    @michaelgully4630 Před 3 lety

    German shepherd X thylacine = Belgian malinos this is not a dog but a incomprehensible hybrid climb trees sits like a kangaroo 90° gate is possible if you sneeze or cough. My female maligator is always tending to her poach that is no longer? # plenty gorge Melbourne

  • @elephantgod7865
    @elephantgod7865 Před 2 lety

    If you will become a successful next to clone extinct animals is Ngandong Tigers

  • @murdomacleod2371
    @murdomacleod2371 Před rokem

    Never mind cloning it ,👎🏼 just find it !!!!👍

  • @grose2272
    @grose2272 Před rokem

    Mammoths could only go back into the tundra..

  • @andrewbaron8713
    @andrewbaron8713 Před rokem

    There are way to many sightings for the Thylacine to be extinct. No need to clone it. It’s still out there.

    • @ericmueller6836
      @ericmueller6836 Před rokem

      There are bigfoot sightings every year and they never existed. Eye witnesses are the worst witnesses.

  • @tomjones2121
    @tomjones2121 Před 3 lety

    how could it be an apex predator with the existence of dingos and crocks and venomous snakes ? I suspect lots of them were done in by all 3 of those species , I read Apex as top of the food chain , in fact I'm pretty sure a large Roo could kill one

    • @Sawrattan
      @Sawrattan Před 3 lety +3

      Apex in terms of evolution, it was evolved to be at the top. Obviously in practice a dingo would be apex, but dingos were invasive species so don't really count, like cats in New Zealand for example.

    • @davida.4933
      @davida.4933 Před 3 lety +1

      @@Sawrattan A male thylacine could probably handle a dingo, but overall since dingos hunt in packs dingos had the upper hand.

    • @barbeeska
      @barbeeska Před 2 lety +3

      Yes, re invasive species.
      Speculation is that the arrival of the Dingo contributed to making the thylacine extinct on the mainland. No dingoes had made it to Tasmania

    • @VinsUplifting
      @VinsUplifting Před 2 lety +1

      ​@@davida.4933 There are some very large Thylacines on the mainland, maybe even some Thylacoleo type of animals as well. The whole saga with the Dingo is an utter myth. There is more sightings on the mainland than Tas.

  • @cullinforeman730
    @cullinforeman730 Před 2 lety +1

    no one gonna mention her black eye? overall very good video. just concerning

  • @tomjones2121
    @tomjones2121 Před 3 lety

    without living tissue from both a male and a female , this can't be done , I don't think, this animal was a marsupial after all

  • @adrianbeer3039
    @adrianbeer3039 Před 3 lety +1

    I find Comical, that they use , a qoate reference to playing God in destroying some thing ? And being so-called smart humans and trying to recreate Tigers... When the opposite fact is true. God created and Man Destoys ...?!?
    M

  • @ElSmusso
    @ElSmusso Před 2 lety

    I WANT A dodo 🦤 as a pet