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The Basal Ganglia - Direct and Indirect Pathways
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- čas přidán 17. 08. 2024
- An overview of the basal ganglia and the direct and indirect pathways model, as well as how this applies to Parkinson's disease and Huntington's disease as well as their potential treatments.
I was dying to learn this , NOW I'm crying because of your video . T-H-A-N-K Y-O-U
This has helped me so much to prepare for my exam, thank you!! So clear and simple visuals.
Trust me, this is the best explanation available here in youtube, sime. easy. concise.
These are some of the best neuroscience videos on youtube. Good speed, through explanation, and EXACTLY the proper amount of depth for someone studying. Many videos are too "overview" or too stuck in the minutiae. Please make one about neuroanatomy of attention!
One of the best explanation video about basal ganglia I have seen in CZcams till date....simple, clear, concise, descriptive.
It especially gives confident for the viewers that they gained some knowledge about basal ganglia without confusions...keep it up✌✌
Best video I've seen on this. Thank you!!!
Thank you so much ...i havn't understand this from any other video ...but thanks to you i have grasp it better now..
This explanation is tooo good! Thank you soo much!
This video is very helpful. Thank you !
excellent, learned this very well in 10 mins
This is gold!! Thank you for uploading this
perfect video. helped me learn very quickly. thank you!
Most concise and most valuable video on CZcams for basal ganglia, thanks!
This video is simply awesome. I have looped it for over 10 times every time I need to review the pathophysiology of Parkinson's disease. Thanks!
This is like GOD sent me this video 😭. What exactly i was looking for
Thanks, this is the best explanation I've seen!
Another awesome video! Please continue making more
blooody awesme mate!!!! that was a trademark 007 description! keep it up! i m ur subscriber from now on
This helped me out so much. So easy to understand. Thankyou!
I finally understood pathways after a very long time!
Thank you
Excellent
Keep making more !!!
Thank you. You SAVED OUR LIVES U DA BEST!
At the end of serching a lot ,I clear my concept from here.Really helpfull ,keep sharing such Vedic.
Excellently explained
The explanation simple, easy and awesome. Thank you soo much
Thank you so so much! Cannot explain the satisfaction from finally getting the direct and indirect pathways. I watched a couple of other videos, but yours is by far the best explained.
great video!!! amazing explanation.
This is honestly the best explanation I've seen! Thank you :)
Thank you so much! Your clear, quick and concise explanation finally helped me realise how the dopaminergic modulation by the SNc was connected to the direct and indirect pathways. This has been a big help
This is incredible - thanks so much!
Thank you so much . This video is so helpful !!
thank you so much. this was really helpful!
You made it easier thank you 🌹
My Globus Palidus has exploded after watching this video. Good work 👍
A big thank you, simply amazing
Nice and clear. Thank you
Thank you so much for clearing it out ! I found it very useful
Nicely explained!! I used it for quick short review .. thanks
Great explanation. Thank you so much 🙏🏼
Loved it ...I wasted 2 hrs studying this...learnt in few minutes
amazing video! highly comprehensive! :) thankyou!
Very clear explanation and drawings!
thank you so much!!! this is very well explained!
honestly, that was so helpful
finally i undertood it, Thank you so much
Thank you soooo much
I have seminar tomorrow n this was the best way to learn, and guess what i liked it, as it was v interesting.
smarty summarized n superbly described :) thank you
This is great, best explanation so far. I hope you continue making videos!
Beautifully explained 👍👍
It's such an amazing explanation!!! I saw many video about these pathways before but just this... is the best version I've seen. Thanks you so much
This. Helps. So. F. Much.
I'm shocked.
omg I'm still speechless. this helps a lot. Like,, a LOT. No i have a better understanding with direct and indirect pathway, i cant thank you enough for this, but thank you very much🙏
This is amazing! Thank you so much!
Best video ever
Thank you very much! This helped me a lot :)
OMG! I love this... best explanation so far... with pathology of 2 diseases... but how about hemiballismus?
excellent video!
Thank you so much. It was so helpful.
MY PROFESSOR IS AWFUL AND YOU ARE A GOD THANK YOU FOR THIS
Absolutely brilliant! You're awesome!! :D
You finally solved my problem in this part after a long time ago. Really appreciated that!
Great job. Very succinct in less than 10 minutes. Very useful for my USMLE
best video ever. thank you.
quick and simple!
Very helpful to learn for USMLE
It's Short but yet in depth and made easy for understanding, Thank you:-)
Thank you so much!
Bless your soul
Thank you!
I loved neuromedicine just by watching this video...thank you
Fantastic video, but you should fix the volume level throughout the video.
Awesome! Thanks!
Very well explained; concise yet comprehensive. Thanks a lot
Brilliant.
This video is amazing. Thanks
Hopefully someone can help me answer some questions!
1) What kind of neurotransmitter is transmitted from the premotor cortex to striatum?
2) How does striatum know to synapse with GPi or GPe?
3) In Parkinson's Disease, why is the indirect pathway favoured?
Great work....keep it up...👍👍
thank you so much
awesome really appreciate it
thank you
Great video and I hate to bring this up but isn't ganglia a term reserved for grouped nuclei outside of the CNS?
Amazing! Never seen such a good explanation ! Bravo
Excellent explanation
You good sir have helped me so much! Thank you for creating this video. Liked and Subscribed!
When we are considering an indirect pathway without the involvement of DA, the cortex is exciting the Striatum and following on from here we will eventually get to inhibition of the Cortex =withold movement. However, using the D2R in the Striatum, you start by inhibited the Straitum so, shouldn't the final outcome be opposite of excitation of Stratum i.e you end up exciting the cortex = movement initiated for the Indirect direct pathway involving D2R. Can you explain this?
thank u sooooo muchhh . deserves 10 milloin likes
this help me a lot. thank you 😭💕
Really good explanation of the topic, cleared up a lot of confusion on the topic for me!
You saved me from failing my exam! :D
amazing! thank you !!!!!
Thank you, this helped a lot! Could you comment on the role of acetylcholine on the basal ganglia? Antipsychotics block dopamine-receptors in the striatum causing parkinsonism. Anticholinergics release these symptoms (at least partially). How do the acetylcholine-neurons integrate in this model?
I am prescribed Procyclidine, it is an anticholinergic, a great drug which acts on the acetylcholine system of the brain. I know that acetylcholine is an important neurotransmitter, the effect of this drug is not only alleviation of any side effects but also a really good boost in mood especially if the person taking it were really depressed. It's not used in the NHS or in the world as an anti-depressant but I think it's a really good chemical and would be perfect for cheering people up who were feeling sad, or feeling demotivated. It's not safe to overdose, it's non addictive when taken at safe dosages I have found myself, I take a dose of 10mgs a day and then, even if life can be depressing, I am still reasonably happy. Not all of the anticholinergic drugs boost mood, but Procyclidine seems to do it quickly and very effectively.
You explained the entire physiology n also the two most imp diseases in basal ganglia in a span of 8mins!!! which cud be vry well understood..thanqq soo much Sir!!
kaushik golagana for short crisp videos about everything in physiology, pathology, pharmacology , medicine.. visit physiologyopen
Basal ganglia physiology | Connections and functions | Direct & Indirect Pathways |Movement disorder czcams.com/video/oQYY84JTak4/video.html
That's spot on! Great supplementary video to my lecture material that I was studying
Amazing 🙏🏻 thank you 💘
Great help!
This helped alot, thx!
Thanks alot
This was really great revision, thank you!
helped a lot! thanks!
Absolutely amazing! Really well explained :)
amazing video! explains the circuitry very well
the best! thanks !
Hi do you have any references or places where you got all of your info from?
C H well for all information from standard textbooks.. you need to check out physiologyopen: Basal ganglia physiology | Connections and functions | Direct & Indirect Pathways |Movement disorder czcams.com/video/oQYY84JTak4/video.html
Amazing!