A New LDL-Cholesterol Theory Coming to a Doctor Near You
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- čas přidán 24. 07. 2024
- Lets discuss a new LDL cholesterol Hypothesis...
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----------------------------------------Show Notes-------------------------------------
0:00 Intro
7:32 Main points of the study - Jak na to + styl
45 years ago at school I was taught that cholesterol is essential for human health. I was the only person in my class who did not go to study medicine at university. I have stuffed myself with minimally-processed, cholesterol-rich food all my life. In my 60s my BP is 95/55. I have avoided sugar ever since I came across the work of Prof Yudkin 42 years ago. I have not seen a doctor in the past 8 years. I have never even bothered to ask for a cholesterol test. I am disappointed on a day where I don't eat at least 3x the recommended amount of cholesterol.
Hi. I wondered what your cholesterol rich foods you enjoy? I love my eggs, but which others would you consider healthy choices?
@fredodonnell3323 that would be any animal fats of course. Steak, butter, cheese etc etc
@@fredodonnell3323 I eat about 250gms full fat cheese a day, about 340gms of beef or lamb. Other days I alternate adding either fatty fish or eggs. And add butter or tallow to every meal.
u should probably also tell people how active you are each day, vs someone just sitting on the couch watching news and netflix
Carnivore is really simple. Eat when your hungry, stop when your full. If you exercise you'll be hungrier. If you don't exercise your body won't need as much so you'll feel fuller faster. Listen to YOUR body.
Dr Berg started using a very apt analogy. They keep blaming the fire men for fires because they are always present at a fire.
15 years ago my older brother had heart attack in the hospital while he went there with his wife-doctor specialist in diabetes. My brother was experiencing pain in his chest and trouble breathing so she decided to visit hospital with him. After they left the ER department where they declared him healthy and sent him for an X ray for pain in his shoulder he collapsed on the stairs and almost died. Defibrillator didn’t resuscitated him at all, one of doctors hit him in the chest with his fist and this brought my poor bro back to life. His cholesterol and LDL was normal. Now after years on statins and filled with stents his cholesterol is extremely low, his life miserable and he and her, the wife believe statins saved his life. Hard to not to agree with them 😂. I’m carnivore for 6 years my cholesterol is high, always was (stoped going to doctors after you know what so don’t know my current 🎉numbers) I never took statins in my life although I was pushed by my doctor since I was 60! And I love my fatty T-bone steaks! My younger brother 70, has 8 stents and he’s plant eating because red meat is the way to graveyard 😂 he’s also on statins. My third brother 72, drinks heavily all his life but since few years he is eating more meat and he’s more or less ok. He took 3 shots though and now he started to age rapidly. He never had heart problem and now is on statins, brainwashig working! All of my other brothers fully vaxxed and supporters of current things. I’m 73 healthy and strong with good muscles
Well done
Interesting term “trapped LDL”. LDL, in the atherosclerotic process, is a repair mechanism. It’s supposed to be there in an attempt to repair the endothelial damage, which occurs in specific, more turbulent, areas of the arteries. As a result of doing what LDL is supposed to be doing, “repair”, it ends up being part of plaque formation; surprisingly, comprising only 1/10 of 1% of the total plaque. The only reason LDL continues to get any attention is because of the continued messaging that it is causal. Atherosclerosis is due to chronically elevated blood pressure, primarily caused by, but not limited to, inflammation due to a poor diet. Thank you for spreading the word on this.
Can you please explain in detail what causes damage to arteries
@@FactsCountdown The video did a great job of explaining that, were you not paying attention? He repeated it numerous times, I mean, many, many, many many many times.
@@FactsCountdown The best explanation I’ve seen on CZcams is by Dr. Abs, Drug Companies Lies: Cholesterol = Heart Disease .
I'm reading a book called The Clot Thickens, and he describes the cause of Plaque isn't from LDL but from damage to the artery wall. When the wall is damaged, a clot is formed, and then the wall grows over the clot. LDL is not the cause, but particles of LDL can be found in the area but not the cause. Anyone else read it? I'm not done but it's fascinating. Not sure if it's true or not?
Yes Dr Malcolm kendrick wrote this book an expert in this field.
@@eddkennedy6458 Malcolm Kendrick isn't a lipidologist, he's not an expert, he's just a family doctor, and a moron. There is no lab experiment where elevated LDL didn't single handedly replicate the disease.
Highly recommended book. The Clot Thickens ties up all the loose ends.
Im 69, my LDL have always been on the high end and is now skyrocketing because I eat "to much fatty meat". Well, I checked everything and have no plack anywhere. But Im healthy, never smoked, stoped drink 15 years ago, but I had slightly high blood pressure. Now down. Slim and look fit. :-)
I might be a hyper responder.
Malcolm Kendrick is one of the most respected thought leaders in this arena. What he teaches should be made compulsory for all doctors. But then I forget that 93% of doctors are pharma reps ☹️☹️
I have always believed that cholesterol was a balm to soothe inflammation. Inflammation is caused by sugars,omega 6 fats, trans fats, and other highly processed foods,stress, and poor living habits. Your vid is right on. Thanks.
Well your belief is wrong. Elevated LDL is itself inflammatory, it in itself does the damage to the arterial wall. Mutzel here is a complete idiot, and that's being polite.
Like literally when I was at my healthiest working out tones they did testing, and my cholesterol is very high, but that was just because I was using more fats for fuel
Experts not taking bribes already said what cholesterol is. Your body makes it to build and repair cells.Including your brain. LDL is low density so it can pass through cell walls. Cholesterol in the skin makes Vitamin D when exposed to sunlight. It makes testosterone in men.
@@gatesroyale,
You are probably familiar with the ideas about the Lipid Energy Model (LEM) and Lean Mass Hyper Responders (LMHR) that Dave Feldman and Nicholas Norwitz, PhD have been investigating, but if not then you might be interested in their videos here on youtube.
@@ArcoZakus yes actually I first heard of it about a week ago on this doctors carnivore CZcams channel. Can you send me the link that goes further into detail?
Mike, you say that we should show our doctors this research about LDL not CAUSING atherosclerosis. That's exactly what I did with my long time cardiologist. What did he do when I handed him several articles on this topic? He belittled me and then he terminated me from his practice. And there lies the PROBLEM!!!
Your doc did you a favor....revealed his true self
He somehow felt threatened by the information!
Yes they are scared witless of confronting the industry.
LDL is a transport mechanism of cholesterol and serves a useful purpose. It's the damaged LDL due to factors like diabetes and other oxidative stresses, and especially combined with hypertension, diabetes, and smoking that promotes plaque formation from damaged LDL. It's kind of like trying to mitigate fatalities from car accidents by getting rid of all the cars rather than reduce causes like drunk driving. They're not focusing on the causes.... the vid is spot on.
Correct sir! I was absolved of the bullshit in 2012 on cholesterol. It is low density so it can pass through cell walls and carry nutrition.
I developed arterial plaque sufficient to cause a 90% blockage, leading to a heart attack, 11 years ago. Was not diabetic in any way, not a smoker, not actively hypertensive ... in other words, those things are not prerequisites for developing. plaque. I did, btw, reverse my cvd, by any measure, through eating a diet of whole plant foods. This guy can be kinda clueless.
@@tspicks4360 I had a 99% blockage, however no heart attack, luckily. I required a quintuple bypass. I have used a keto diet and fasting to dramatically improve my health and my high blood pressure. I lost 33Kgs and feel fantastic...
_'Damaged LDL cholesterol'_ - what are you talking about???😅
@@tspicks4360 Check out the oxidated linoleic acid theory of heart disease.
70% of people who have a heart attack have normal or low cholesterol. The study shows these people had low cholesterol at least a year before their heart attack, it's not cholesterol but diabetes, blood clotting issues and smoking.
You missed hypertension.
@@thelaststylebender1678hypertension is normally due to insulin resistance " diabetes" or high homocysteine. But you're correct thank you.
Minority of people are also causing damage from overtraining.
But what was their cholesterol for the decades before? It’s about the area under the curve, not a point in time. Many people adopt a healthy diet once they’ve already done substantial harm.
I've come across the oxidated linoleic acid theory of heart disease on CZcams from the channel Low Carb Down Under. Basically, linoleic acid from seed oils build up in the body because the body cannot use this omega-6 fatty acid for energy. So this builds up over years and oxidizes and damages the cholesterol that it is a part of and explains why LDL gets trapped in plaque.
I’m a doctor working in internal medicine & I’ve made a video discussing dietary fat and cholesterol!!
Don’t know when doctors will start using their brain.
They will NEVER let go of LDL-cholesterol because drug companies just want to create more and more drugs.
Gotta make those payments on their BMW’s.
What do you say about Dr Thomas Dayspring?
@@jeffj318 I’m not convinced. Personally I have seen people reverse atherosclerosis with a ketogenic diet. I have seen people reverse autoimmune conditions, schizophrenia & depression, and even dementia with keto/paleo!!
a whole food plant based diet is definitely MUCH healthier than a SAD, but I’m not convinced that a vegan diet that lacks bioavailable proteins, omega3, vitamins and minerals & is rich in anti-nutrients if not carefully planned is evolutionarily appropriate for humans.
@@jeffj318 A quick look through his page he claims ketogenic diets increase apoB which means they increase risk of heart disease.
Thing is that apoB tells us the sum total of apoB containing particles that include VLDL, IDL & LDL.
In case of insulin resistance, this would be high because the VLDL number would be high, and so would the NUMBER of small LDL (atherogenic type). It makes sense that then, apoB is high in these phenotypes.
Now, in case of ketogenic/low carb diets, LDL-C goes up, but the number of LDL particles may go down, and VLDL definitely goes down. Even if LDL particles are high, they are the large fluffy LDL particles which are not atherogenic, and do not get damaged.
So most studies on apoB that show a higher risk would most likely be showing us an insulin resistant lipid profile rather than a metabolically healthy lipid profile. Since most people who have heart attacks have insulin resistance, they will most certainly have a lipid profile that has high apoB.
I am not sure if we can extrapolate these most common studies to a metabolically healthy phenotype. We definitely need more studies on metabolically healthy people with high HDL-c, low TG, low VLDL, high LDL-c, and maybe even high apo B and do advanced testing such as CCTA/CAC on them to see what their cardiovascular risk may be. But for now, we don't have sufficient evidence. But, my opinion is that just looking at apo B in the context of an otherwise healthy lipid profile JUST because of high number of fluffy LDLs is not prudent.
Hope this makes sense!
… to make more billions
Hey Mike, have you read Dr. Malcolm Kendrick's book, "The Clot Thickens"? In his book, Dr. Kendrick opines that if a person's coronary glycocalyx and coronary endothelium is healthy and intact, there ain't NO WAY that atherosclerosis can even start, whether your LDL-C is 20mg/dL or 250mg/dL. To your point, it is high glucose, high insulin, smoking, hypertension etc. that actually damages the glycocalyx/endothelium and initiates the atherosclerosis process. As Malcolm Kendrick says, there is ZERO evidence, in ANY medical literature, that proves that LDL, or ANY liporprotein, including small dense LDL's and VLDL's, can damage/disrupt the coronary lining! As lipid researcher, Dr. David Diamond, points out, there are many people with familial hypercholesterolemia, who have LIFELONG high LDL-C, and they do not develop premature atherosclerosis.
What about this APO B lipoprotein that many are now blaming for the damage ?
@@mkkrupp2462 Great question. Since most of our ApoB level is composed of the LDL particles, the ApoB blood level is about as useful for predicting atherosclerosis as LDL-C*****WORTHLESS. As Dr. Malcolm Kendrick says, "LDL-C, LDL-P, ApoB, small dense LDL's are all essentially a distraction which leads us away from the real cause of coronary artery damage----high blood glucose, high blood insulin and INSULIN RESISTANCE.
Any “study” you find that says “May cause” you probably need to replace it with “May Not”.
I have had high cholesterol since my first blood test at 30, I am 60 and have never taken statins. My blood pressure was always 130/77 and the doctor always told me I was fine. Now that I am a carnivore and fast for approximately 16 hours on average, my blood pressure is 110/65. I have always done a lot of sports, even at 60 I continue to play soccer competitively. My VO2 MAX is 47.
Vessel wall damage is the root cause but they will always focus on the thing they can create a drug for.
And therein lies the rub. Follow the money! Eating correctly never makes big pharma money!
You're a good lad Mike!
You genuinely care.
I can hear it in your voice
"Stop smoking! What are you doing??"
A step in the right direction. But, when is a study going to be published on how the body repairs the damage caused by smoking,diabetes or high blood pressure?
Water fasting sauna collagen peptides, good sleep, grounding and days with stannous exercise endurance plus days of deep deep rest more then 8 hours all help. Controlling your pH as well. Could it be beneficial like having lemon and water.
Thanks Mike. With papers like this maybe finally my parents to listen to me, about how cholesterol itself isn't the underlying problem with cardiovascular disease. It's nice to see studies like these catching up to what many of us knew years ago. Maybe in another 10 years the mainstream will recognize how blood sugar is more of an issue with blood pressure than having salty food.
Do you blame the firemen for the fire? Cholesterol is a fireman at a fire. HELLO What is causing the fire? Processed Veggie/Seed Oils, sugar, processed foods.
Mike, so well said, thanks for emphasis of the "other factors" ie. what insults the inside of walls of blood vessels,HTN smoking/vaping, high blood sugar damage iron overload....excellent work Mike.thanks
Finally doctors are doctoring… shocking this was not correlated until now
My cardiology professor has put me on an LDL reducing drug called Repatha it does work where nothing else has and is also reported to reduce existing atherosclerotic blockages. Once I believe its done that I will stop taking it.
good read "Atherosclerosis during periods of food deprivation following world wars I and II"
good read "Robert Tattersall takes a look at the historical impact of war on diabetes, highlighting the seemingly odd occurrence of reduced diabetes prevalence and mortality during wartime food rationing"
One of the underlying causes that seems to get little mention nowadays is chronic stress. High cortisol levels cause hypertension, and there is some interesting research indicating that cortisol may also damage the endothelium of coronary arteries.
Interesting link and anything else?
Cortisol is corrosive to arteries
@@gatesroyale overtraining is another, obviously most fall on opposite side though. Some individuals get on a treadmill for hours keeping their heartrate way too high. Do that multiple times a week and you have damage that can't repair fast enough.
@@jackoverton8343 thanks for sharing this. I actually witnessed this personally.. you can basically I believe overuse your adrenaline glands and be such a high of Cortizone for so long within a months time you lose all energy. I think the best protocol is you can still keep that high schedule, but two days in between with rest..
Casey Means talks about this. Stress, lack of sleep, and lack of exercise are as big a problem as bad diet.
Well they need to go deeper because you know damn well there are folks living to a ripe old age with a high LDL, Low LDL is dangerous too! Maybe some folks are affected but certainly not all. Yes type 2 diabetes and obesity are risk factors for so many problems!
It's not so much that they're risk factors, they're just the most obvious symptoms of the same metabolic dysfunction that is causing heart disease and many cancers.
In my humble opinion HDL and LDL are not cholesterol.
It’s better to talk about High and low density lipoprotein.
The HDL and LDL are just transporters from the cholesterol. The HDL deliver the cholesterol in all the places in our body where it’s needed. And the LDL brings it back to the liver.
Thanks for the video from Thailand.
I think the live videos are really authentic, a nice change from the typical highly edited youtube video
After you download and read this paper I urge you to find and read a book named "The clot thickens".
Then continue doing more research in the competing hypotheses (cholesterol vs. thrombogenic), and decide which one makes more sense to you.
Oh, and please get your doctors to read that book as well.
To your (our) heart health.
I love every single one of my LDLs! As long as my trigs are low I have no fear. And they are at 43 after 18m on a keto diet with 18:4 IF.
You lost two hours 😂, 18:4…
Okay, if blood pressure is what causes atherosclerosis, then we should stop using mouth-wash. The most common cause of blood pressure is inability to produce NO2. And the most common cause of reduced production of NO2 is excessive fluoride consumption. If you already avoid using mouth-wash, and yet have a blood pressure problem, the second most common cause of insufficient NO2 production is arginine deficiency. Either supplement with arginine or citroulline, which we can convert to arginine; or eat a cupfull of watermelon every day.
Another thing: If you are past 40 or 45 and you have arterial damage, your body cannot repair the damage due to minimal production of collagen. Taking collagen supplements will not help, because ingested collagen gets digested down to amino-acids and small peptides; so to re-constitute those nutrients back into collagen you need a ton of vitamin C, plus the amino-acid lysine.
The only way to restore production of collagen after 50 is to follow the Pauli protocol, which is basically 6 grams of vitamin C and 3 grams of lysine per day. That is the MINIMUM; personally I take
10 to 12 grams a day of vitamin C per day. Before you think of the word "mega-dose", consider that humans and orangutans are the only animals that are not capable of producing their own vitamin C. Your dog produces about 17 grams of vitamin C per day. A cow produces more than 100 grams of vitamin C per day. And you might ask why don't we produce it too? We lost the ability. We still have the gene for vitamin C production, but the gene is not getting activated; nobody knows why. Anyways, back in prehistory we did not need to consume vitamin C as citrus fruits or as supplements, simply because we hunted animals for food, and ate them raw. Raw meat has enormous amounts of vitamin C. Cooking, however, destroys it. And no, I am not advocating eating raw meat; that's dangerous nowadays. I'm just saying all that because people have such naive perspectives on nutrition you have to write a whole paragraph to explain each word you write. 99% of people are completely incapable of taking in eve a small piece of info, like the importance of the Pauli protocol to reactivate collagen synthesis. 99% of people just don't click.
Another thing is the gradual clotting of blood as we age, which increases viscosity. There is one simple solution to that: Japanese natto. Consume it, and your blood will quickly go back to the fluidity of a 20 year old's blood. Just eat one square package of natto every other day; the enzyme nattokinase present in it, dissolves blood clots. Natto smells and tastes awful to our western taste, but so, what I do is I fry the natto together with onion, garlic and ginger, and after 15 minutes of frying I throw in a couple of eggs, and make it an omelette or scramble.
Won't the heat from frying natto destroy the active enzymes?
@@jrket8141 No, it doesn't. I never eat natto in any other form than fried, and I notice the difference natto makes in my system whenever I hurt myself and bleed. Same day after eating natto, a wound takes 2 or 3 times as long to stop bleeding. This is precisely because nattokinase in the blood is dissolving the blood clot even as it is trying to form. I once ate natto twice in one day, then hurt my finger, and I was wiping blood with servillettes for the next hour and a half. So be careful. But to answer your question, nattokinase is definitely NOT denatured by the heat of frying. And in fact, cooking doesn't destroy as many things as most people assume. Vitamin C is definitely destroyed by cooking; that is a famous case. And some B vitamins. But most vitamins are detanured by heat, but very slowly; so you might lose a few per-cent potency over a 30 minute boil. You have to check one supplement at a time what cooking or heating will do; there is no blanket rule that can be applied.
@@privateerburrows Thanks
Watching from the Los Angeles area. I really enjoy your content and information. Thank you for the work you do.
It appears settled science is changing again.
people should read ' The Clot Thickens'. Dr Malcolm Kendrick
The length to which you go to find that one argument that goes your way in a paper literally saying that the magnitude and duration of exposure of LDL has a direct impact on progression of atherosclerosis is pretty amazing.
The paper does suggest that there's a lot of benefit to be had by lowering LDL cholesterol levels e.g. with statins which does kind of conflict with a lot of advice saying LDL isn't 'bad' and you don't need to reduce it. I'm completely confused to be honest, my Dr is adamant I should be on statins but I've been avoiding taking them but I'm beginning to question the wisdom of doing that...
I have heard enough about blaming the firemen.
Well, the results of this study do suggest that the firemen are actually setting the fire in this case. High blood pressure and diabetes increase risk even at lower LDL levels. People with high risk do not get a higher LDL level as a result of high blood pressure or diabetes (in which case the relation between risk and LDL levels would be similar for people with diabetes and high blood pressure compared to the general population).
@@GerbenWulff Fatty liver causes the small dense LDL.People with high good LDL live longer.
Perhaps a better analogy would be to imagine damage is done to a road. Workmen show up to repair it. As a consequence traffic is congested. But before the damaged road can be fixed, more damage occurs, causing further traffic congestion. And the process continues until traffic is halted altogether.
@@michaelkrull3331 ,
... and the damage to the road never gets repaired.
@@GerbenWulff No The firemen are not setting the fire. sugar, veggie oil/seed oils oxydative stress due to natural aging process, these are setting the fire.
Listening/watching from Singapore. Always glad to see/hear your content 👍
❤great video. Loud and clear, Baton Rouge. Listening to replay. Evangelize the culture.
Malcolm Kendrick has been saying this for years.
This reads like a paper funded by people who wanna sell Statins
And the new injectable drugs that get your ldl down to 35. That’s safe. No risks at all. Totally safe and effective.
Association is not causation!
Watching replay from Switzerland, thanks for all your videos!
Professor Bart Kay has been ranting about high blood pressure and turbulence as the root cause of ASCVD for a while now. Additionally, this paper advising reducing LDL "as low as possible" is utterly absurd.
LDL is a big red hairing, it has nothing to do with heart problems. Stress has a huge effect on the heart. Excessive sugar in the blood causes inflammation of all arteries, huge sugar spikes regularly are with their effects. All plaque formation when broken down have fibrin in them from blood clotting. LDL cholesterol is a lipid transport system. Stress, inflammation from high sugar diet, poor metabolic health, causes damage to the epithelial walls of the arteries which can rupture and clotting of blood occurs then plague formation occurs, fresh formation that have not had time to mature can rupture again or several times causing bigger blood clot which can brake off go to the brain causing a stroke, or they can go to the arteries of the heart causing a heart attack. These one are apparent immediately but this happens to all your arteries, other parts of the body can have claudication caused by inflammation due to poor metabolic health and too much sugar.
Red HERRING...
Dr malcolm kendrick wrote about this in his book the clot thickens long ago
Just love your passion and knowledge Mike. Keep on m'dear. 🎉👍😁
I've been saying for years, ever since before I started University that cholesterol is more like a patch material and not some evil substance out to destroy your body. and taking away LDL is like removing all the wall patching material in your house without addressing the hyperactive children playing contact sports in the house and punching holes in the walls in the first place. If you have no holes, you don't need patch kits, but if you have to patch the walls regularly, getting rid of the spackle won't solve the damage problem.
Being a young person, I didn't have studies to back me us so I wrote stories with characters representing the different cells and substances and got made fun of because of it. I figured people are too stupid to read a study so maybe a story would help them understand, but they were so indoctrinated to the Lipid Hypothesis, they couldn't suspend that belief long enough to think critically about it. Now decades later, studies are finally showing I had the right idea, but what good does it do when people are still afraid of eggs and downing statins like candy?
Since the carrier is just going out and coming back, that'd be like saying we need More Empty Busses going out to transport people, but we need to LIMIT the busses carrying people to their destination because they get sometimes get stuck in traffic. It's the Same Bus!
This research is not differentiating Type A and Type B LDL-C. Type A LDL-C is highly dependent of dietary fat consumption while Type B LDL-C is dependent of high blood glucose level. And the one which causes atherosclerosis is Type B LDL-C which statins cannot lower.
Agreed. It is weird they did not account for that or even talk about it on the paper, if they have such a good handle of the topic.
Yes, it's true! I just fact checked this info on pubmed.
I wish my doctor would do a little research on this. She is trying to push the statins on me!
Yes, it's true! I just fact checked this info on pubmed.
I wish my doctor would do a little research on this. She is trying to push the statins on me!
Also, my oncologist told me about this type a and type b LDL C.
She seems to know more about cholesterol than my GP.
I AM CANCER FREE after 18 months keto/carnivore , NO CHEMO!!
@@andreahatfield1456 If it is type B that is caused by high good glucose levels that is the bad one. Try berberine, chromium/vanadium and TUDCA. I give this to my parents to keep their insulin sensitivity up.
Hello from South Africa 😊
Thanks for the informative talk!
...en ek ook.
Blood pressure is a major factor and salt is involved there: The salt contribution seems to be a product of low dietary potassium. That stiffens the arterial wall assisting calcification that attracts LDL as a healing agent. Or so the story goes, so far.
CZcams used to be more reliable giving me notifications for your streams.
Reducing range for anything which doesn't fully support the establishment narrative is yet another form of censorship. As is likely that my comment may not be visible to anyone but me or get deleted automatically straight away after I post it.
Sometimes you have to unfollow to follow again to get notifications. YT does that to me too.
Why does low density cholesterol exist, what is its purpose? I believe the our bodies don’t process high refined oils and fat substitutes that leads to fatty liver and more damage to body cells that need cholesterol to repair nerves and joints.
This is why I take Magnesium Glycinate and Liposomal Vitamin C and this is keeping my vessel walls are being healed. I am from Colorado
I drink sodium hyperchlorite to keep my arteries clean 😂
Collagen peptides, fish oil and a hot sauna help as well.
@GregariousAnrhat that's bleach, surely you jest😮
@@GAB-kw7uk i joust
@@GAB-kw7uk the irony is i can make such a insane remark and it doesnt get deleted by youtube yet talk about minerals and diet and it gets deleted.
I am a regular viewer of your videos.
I want to share my experience with you.
From 2021 to 2022 I used to do regular intermittent fasting and prolonged fasting. While doing prolonged fasting then I used to get into ketosis and I knew this from the smell of my urine.
After almost a year I did a 3 day water fast and I wore a CGM my sugar was continuously above 130mg/dl. Sometimes it went to 160 also.
I don't think I was in ketosis because there was no change in urine smell.
Also I was absolutely fine unlike the earlier fastings when I had a lot of discomfort.
I feel fresh with much greater mental clarity and energy to do physical activities.
Was my body creating glucose through gluconeohenesis ?
I think you should do research on type 2 diabetes patients to see how fasting works for them.
Pls do reply at your earliest convenience.
Best Wishes
Colonel Madhusudhan Nair . Retired
India
I think Dave Feldman's camp has postulated/found that (healthy) LDL is part of the body's repair process for the insults.
There is no unhealthy LDL, fyi.
@@bobann3566 Actually, there is. LDL cholesterol that has been damaged by glycation is bad. (Glycation is the covalent attachment of a sugar to a protein, lipid or nucleic acid molecule.) Glycation causes plaque build-up. When you don't eat low-carb, you will have a high % of damaged LDL. That is why (for the 95% of the population who does not eat low-carb) there is a statistically relevant relationship between plaque and LDL. The problem is that doctors believe that all LDL is bad.
@@PeterDuval You are blaming the fire on the fireman because he got burned.
@@bobann3566 Sure there is. Glycated LDL. LDL made with damaged proteins. This stuff can even be measured.
@@mikeward9870 LDL does not come glycated, that happens to it through foolish choices when it comes to the one thing I have total control over, what I put in my mouth.
I will be more specific. When will a study explain the mechanisms the body employs to repair damaged arteries from smoking, diabetes and high blood pressure?
I forgot how great is starting the day with a Metabolic Mike deep dive!
Greetings from Rome
Man. Love the channel, long time follower here. Please don't change your tone, don't get annoyed. Please. When you talk like that in the end it even makes me anxious. Present please in the usual peaceful form.
Ignores people with Familial Hypercholesterolemia, according to this they should all have ASCVD, yet they don't. Yeah they give a nod to vessel injury....
Awesome content. From Sri Lanka
That is fascinating about things like insulin resistance and high blood pressure can lead to damage to the arterial wall leading to arteriosclerosis. I like how you are explaining research papers that I wouldnt be able to decipher on my own, And I really like how fit your looking brother, I like my Doctors to be displaying signs that they know how to at least keep themselves Fit haha! Andre
Thank you for your work from Vancouver BC
Watching from Baguio, Philippines. My LDL cholesterol is also high.
LDL is the vehicle delivering cholesterol which is the raw material used to repair damaged endothelium. Blaming LDL for atherosclerosis is like blaming fire engines for starting a fire.
4:38 Anyone who has read Kendrick’s The Clot Thickens already knew this.
I need some Pop Tarts after watching Unfrosted!!
I didn't see the Livestream, but I'm watching from Sydney, Australia.
You can get an app that let's you know where people are tuning in from.
Hi Mike! Good video and you are looking good today!! Could any Allulose monk fruit sweetener be causing my triglycerides to go up?? Been on a mostly meat diet. Only things that I occasionally consume are some fruit, alcohol, ninja creami treats made with coconut milk and the Allulose mentioned, and some Lily’s sugar free chocolate. One thing I can think of is that I was not fasting with the blood work and had a “wine party” the previous night!
Can you repair the initial insult over time? My concern is whether this is irreparable damage as someone who’s just started working out.
Is it possible the body is depositing cholesterol in area of damage in an attempt to repair or at least aid in repair. The body doesn’t have another mechanism to seal the vascular wound while repairs are carried out? So eventually a rupture of cholesterol plaque kills us but without the initial damage the cholesterol is irrelevant? Or is it a case of cholesterol getting stuck in a vascular wound as it’s flowing by in the blood stream?
Watching from Tasmania Australia
Great presentation, Mike. Could you tell us where we can go to download a FREE copy of this paper by Ference, et. al.?
Thank you from Toronto Ontario.
Thank you for this info. For someone with known endothelial dysfunction (CAD and PAD peripheral artery disease) based on this info would you think it important to lower LDL assuming they have addressed all the lifestyle things to reduce endothelial injury? Have been resisting statins for many years, been told statiins don't necessarily reduces one's plaque burden and can itself cause metabolic dysregulation and more.
My LDL is 244. (Normal blood pressure, non diabetic)
My LDL is over 300. It's always been high. I eat a keto lifestyle. Alll other markers are great, no diabetes, hypertension low A1C high HDL low TRI. My dr said i'm gonna have a heart attack in a month if i dont go on a statin. Well its been months, I should call and let her know that I'm still here...lol
@@rdiemidio65 Another GREAT example of us patients starting to get SMARTER than our doctors!!!📖📈📉🔬🗃📚
From Liechtenstein 🇱🇮 thank you
Listening from Peterborough, UK
Watching from Singapore. High LDL (5.1mmol/L) but low Triglycerides (0.63mmol/L), no sugar, kinda normal BP (125/82) and doctor quite insist to put me on statin…
Do you still offer the bloodwork cheat sheet? If so, how can I download it? I’ve tried several email addresses and never received it. Thanks for your videos.
please share the study links with us. Thx
Please, let know about this to Dr. Alo, Peter Rogers MD, Dr. Neil Barnard and other clowns!
Yes able to hear you
We have to look at what causes LDL move into artery wall. And what cause it to stay there. The early atheroscerotic process is reversable without inflammation and excess oxidised lipids which prevent macrophage from releasing the cholesterol from the plaque. Total LDL association is not causal at all. The small very dense subset of LDL may be more causative because this has many characteristic associated with mechanisms that maintain plaque development. These small dense LDL are not measured and the mostly contain oxidised lipids and stay in the blood for extended periods. They occur in a high Triglyceride environment. So it might just all go back to excess TG.
All this is good.
How do you facilitate Vascular insult repair at this point?
Yes fasting, exercise, sleep, eliminating SAD, so on, but what items can help after the above are accomplished?
Thankz!
Great sound quality here in Loveland, CO
I can't find the citation for this article. I'm curious where the funding came from. That's my top priority regarding how I look at journal articles now.
What do you recommend to someone who was obese and had high blood pressure (controlled with med.) for years, finally turned things around with diet and exercise in their early 50's, are off all meds, but still has high LDL cholesterol? All other markers being in the good range. ? The damage was done, but...now what?
Atherosclerotic plaque is essentially a healing mechanism to repair damaged artery walls because of eating sugar and seed oils, both inflammatory agents. As more damage occurs, logically, more plaque will continue to cover the damage.
Fire truck vs fire debate as always.
I confirmed my email address but still haven't received the blood work cheat sheet. How can I proceed? Please help 🙏.
Grade: A-
Reasoning:
The video provides a comprehensive overview of the new LDL cholesterol theory and its implications for heart disease prevention.
The host effectively communicates complex scientific concepts in an accessible manner, making the content engaging and informative.
Interaction with the audience adds value, addressing real-time questions and concerns.
The video could benefit from a more structured format to enhance clarity and flow.
Overall, this video serves as a valuable resource for those interested in the latest research on cholesterol and heart health, offering practical advice for improving metabolic health and preventing cardiovascular disease.
Please list the study or studies you refer to under your videos. Thank you.
Where can i read the article?
Very interestingVery interesting! Greetings from Italy.
Watching from virginia!! How do i reverse plaque that i most likely have? Im 38, i lowered my triglycerides from 500 to 200 after i got sober from alcohol ( 13 months now) but my ldl is high, but coming down naturally, and overall cholesterol is coming down ( from 220, to 160) ... My a1c went from 5.7, to 5.1 when i got sober, but im interested in starting metformin for its benefits long term
Ive been metaboliclly sick for years, and want to help my body heal, guaranteed i have plaque build up 😢
Hi Mike. If u follow carnivore or keto diet then your LDL become high, Do u quit that diet or add statin to lower the LDL according to that paper ? Pls advice. Thanks.
Lower your inflammation. Get hsCRP etc. If it's low, don't change anything
Watched after livestream from Seoul south Korea
Watching from the Philippines
Please explain how to read Fig. 5 'Median CAC score and lifetime risk of cardiovascular events by levels of cumulative exposure to LDL' There are two horizontal and two vertical axis.
I do not weigh enough to donate blood what else can I do to decrease blood viscosity??? I am barely over and keep decreasing my T and my body loves it a little hight like 200
How do elevated LP(a) levels factor in the risk assessment?
Do you think psoriatic arthritis can cause plaque/high calcium in the arteries? The reason being inflammation.
How about NATTOKINASE?