Farxiga FDA Approved Kidney Disease Treatment. Should You Use It Or Not? *SHOCKING RESEARCH*
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- čas přidán 4. 05. 2021
- AstraZeneca’s Farxiga (dapagliflozin) has recently been approved by the US Food and Drug Administration (FDA) as a treatment for chronic kidney disease (CKD) in patients at risk of progression with and without type-2 diabetes.
This approval is the most remarkable advancement in the treatment of chronic kidney disease in over 20 years. During the DAPA-CKD Phase III trial, the oral drug Farxiga showcased an amazing reduction in the risk of declining renal function, end-stage kidney disease, and cardiovascular or renal death in CKD patients.
Farxiga is the most recently FDA-approved kidney disease treatment that can help tackle many complications that come with kidney disease. Farxiga was originally approved in 2014 to improve glycemic control in adults with type 2 diabetes in addition to diet and exercise. These oral tablets, once-daily sodium-glucose cotransporter 2 (SGLT2) inhibitors, went under review in January 2021.
The ground-breaking approval news came in after a successful DAPA-CKD Phase III trial. The numbers from this trial showed many kidney disease sufferers the light at the end of the tunnel.
During this trial, 4304 patients were randomly assigned to receive either Farxiga or a placebo. By the end of the study, the researchers concluded a 39% reduction in the risk of declining renal function, cardiovascular death, as compared to a placebo in stage 2 to 4 CKD patients with high urinary albumin excretion. AstraZeneca’s Farxiga showed an overall 31% reduction in the risk of death versus placebo.
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it works cause it makes you drink a lot of water that's all, big pharma will try and slip anything past people, they know few can see through it.
this that's a ridiculous thing to say??? do a little research on the effects of a lot of water on blood sugar, hypoglycemia, kidney function, weight loss etc etc.....and they're no bad side effects with water.
just sayin
Your very thorough in the description and well spoken thank you.
I've been taking this for a few months now and I haven't noticed any side effects at all. I don't have diabetes at all, but the doctor recommended that I take this, along with the blood pressure meds that I already take.
Same here! I'm not a diabetic either and the only side effect that I have, is peeing more and that is expected.
Good to hear 👍🤗
I love your program. Thank You
I just got put on this. The second senmtence on the info sheet says, "Farxiga can cause ketoacidosis that can be life-threatening and lead to death." Gotta say, that scares me a bit. I'm sorta trying NOT to die here.
I’m starting this now for CKD stage 3. My nephrologist is excited about this medicine. I’m hoping to keep away from dialysis with this!
Great, but do much more than just the medication. Diet, supplements, lifestyle changes will great help along with the medication.
Same stage 3 ckd a rare kidney disease.
I saw you started this medicine for stage 3 ckd and i have stage 3 ckd as well and i was just wondering if you're still taking this medication and if you had any bad side effects or any side effects at all? I'd appreciate it and hope you're feeling well and thanks.
Did it work for you
Farxiga worked against my health! My vision blurred, I had arthroses pains because this medication dehydrated my arthroses and the dehydration augmented the pressure in my eyes and now I have to prevent glaucoma!
Just had a 2 day stint in the hospital to get rid of an infection. I've been on Farxiga for 6 months and Jardiance for 15 months before that. My eGFR was in the low 60's before I started taking this drugs. My eGFR when I got to the hospital was 35. After 2 bags of saline and some time my eGFR was 57. My doctor took me off the farxiga.
So Farxiga made your GFR worse? That doesn’t make sense. I just got prescribed this leaking protein, and have type 2 diabetes.
Why did doctor took u off farxiga? May I know, coz I’m taking it almost a year now, 10 mgs daily. Does it have a negative effect? Doctor told me it’s good for kidney but I’m also doubtful….
@@evelynaustria5227 My eGFR dropped while taking Jardiance and Farxiga. Now I'm hearing that these drugs increase risk for infection in the lower legs that could lead to amputations. Made me wonder if Farixa is what put me in the hospital. All people are different though.
Same, I started Farxiga in January and just spent 3 days in hospital in May after a UTI that went into my kidney and was going septic. I am convinced Farxiga was the culprit. I’m still on it because none of the doctors I’ve crossed paths with seem to care enough to pinpoint a culprit, frankly. One must be their own advocate in these matters sometimes.
@@evelynaustria5227 I keep hearing mixed messages about it. Great for heart, great for kidneys… meanwhile since I’ve been on it I’ve had a UTI get out of control and go septic, and I’ve been diagnosed with atrial fibrillation. I have no idea if they’re related to farxiga but… sighhhh… I want to know.
Hi do you still recommend this medication for CKD? I saw you posted this video a couple years ago? Wondering your thoughts are now, is there anything better? Thanks. Just got prescribed this, along with Trulicity. For my type 2 diabetes and leaking protein.
l was diagnosed with stage 1, my eGFR blood test says by kidneys are normal but l have some protein in my urine, my doctor wants me to take farxiga but l would rather try diet changes when l am on such an early stage rather then drugs, should l take it , are there side effects
Doc put me on for type 2 diabetes because I was concerned about kidney and liver stress. I'm worried though because it increases cholesterol. So far it's just made me insanely tired and nauseated
Sorry to hear that .. they have some new medications that got approved so maybe you want to talk to your doctor about that.
Can chronic high blood sugar used utg farxiga cause more frequent fungal infections and UTI? I haven't been doing good with my blood sugar and I keep getting these infections every month or so when I;m on farxiga :/
Again... this is Ella... love this content **wink*
Great video thank you! I am a CKD patient with Iga nephropathy, my doctor prescribed Dapa but I am concerned about the glucose in my urine after I started taking it. I am not diabetic. Is glucose in urine normal?
It makes you pee out glucose. It can cause weight loss because it’s literally peeing out sugar calories. This is my understanding. But that sugar in the genital areas can cause wicked infections so look into that.
Farxiga for heart with a kidney transplant? What thinkest though?
The sad part is that even when you talk about SGLT2, the add that comes on is that for GLP1 (Jardience) and the fat lady has pizza served to her (no lifestyle changes needed!).
I would recommend to differentiate between the two of them because I found the difference to be between life and death because I have managed with fasting (with anything enticing not available at home - given my poor self control).
At 70, to have Farxiga is heaven sent, because I had difficulty to fast on cruises!
Do you mean farxiga works for you well? Coz I’m 70 too, taking farxiga for 2 yrs. now. But lately my albumin isn’t good enough and creatinine used to be 80, now it’s getting higher (100) even if I’m on ketoanalogues (9tabs/day)
@@evelynaustria5227 No. The jury is still out.
I was precribed this by my neurologist because i have stage 3 ckd due to a rare kidney disorder but after reading all the comments and side effects I'm scared to take it and i only took it for a few days and stopped but I'm going to talk to my kidney specialist about it. I know all medications are going to have side effects that's just a part of taking medication but some of these side effects are scary.
I’m using farxiga for 3 months already and it did good to my blood works and Microalbumin. One thing I noticed is…. constipation. And planning to talk to my nephrologist.
@@evelynaustria5227could be that you are dehydrated. Need to drink a lot of water.
My left kidney is no function sir totally infected and working 0 % , is this improve my function of kidney...?
I take it for my diabetes
Can you please tell can hepatitis b vaccine taken double dose for CKD patients temporarily increase creatinine?
I don't think so. It's best to check with your doctor or pharmacist. Make sure you drink plenty of water.
Would this possibly help my mother. I have tried all options for her. She was on CRRT in hospital and not on any form of dialysis now. She's on palliative care and I'm a person that is not giving up on my mother. I am always willing to try this for my mother
Unfortunately, you would have to ask your kidney doctor that question.
I’m using it almost 3months now. 10mgs/day
It did good to all my blood works and urine but caused constipation. I had to take other supplement for my stomach.
It sorta works for me my glucose still run a lil high 135 to 180 curious if I'm able take a little insulin with it
I prefer silymarin and proline.
Hi my doctor prescribed it for my CKD but i am scared of side effects, like fasciitis necrosis, I am not diabetic
Its been out a long long time, so check with your doctor about the rss.
Amazing video ! I already told my doctor about dapa but she doesnt want to give it to me ... i want to take it but i want to take it correctly ! Its my kidneys and not hers !
Thank you for commenting. Did your doctor give a reason for not wanting you to take it?
@@HealthyKidneyInc thank you for caring sir , she told me it wasnt studied enough for ckd use and it would take a bit for it to be used for that ... btw iim from portugal so things might take a little bit to get here from america ... i just dont know what to do ..now that it was aproved in europe too i need a doctor to help me with that to find the right dosage since i take amlodipine..
Does it help?
i just started,i have ckd ,prob is protein in the urine,so far painful urination gone,pee more now
@@HealthyKidneyInc I think farxiga doesn’t work for all CKD patients. Others try jardiance or tragenta. I for one is on farxiga, but thinking of stopping it myself
I am a chronic kidney failure patient, I have not been on dialysis, I continue my life on a diet. Does this drug provide a permanent improvement?
You would need to check with your doctor. I am not sure of your issues with kidneys and the MDs are the expert on drugs.
What stage are you, and what supplements you taking?
Hi, I’m Stage 5 CKD, getting ready( as pet my Nephrologist) to get the fistula and soon thereafter dialysis. I would like to ask you if being st this stage, I’ll still be on time to reverse CKD to a certain degree? Thanks very much for your information. Mirza
Sorry, we missed the comment. It sounds like a very advanced stage.
Well, Thanks so much, anyway!
You cannot use farxiga for stage 5
HI doc! Would it be useful for a 23 yr old male with proteinuria,hypertension and glomerular hyperfiltration , without diabetes or any other problems , to take forxiga 10 mg along usual ACE inhibitors which i have been using for 4 years now? thank you very much!!
Thank you for the message. We give general recommendations through videos. We can't give personal health advice as I have no idea about your situation, medications, health history and wouldn't want to recommend something that may harm you.
Why are on farxiga… do you have CKD like us? I’m stage 3B and using farxiga
@@evelynaustria5227 well , earliest stage ckd....so doc wants to take forxiga...still not decided myselft. current sympotms are mostly high BP and proteinuria
I’m ckd stage 3, my doctor prescribed me Forxiga 3 weeks ago and my GFR decreased by 5ml instead of 2ml previously. I’m 73 years old. Is GFR decrease expected ? Will it keep decreasing if I keep taking Forxiga ?
I do not think that is expected, so best to speak to your doctor about it.
I just recently got prescribed Forxiga, but my doc said my egfr is likely to improve by the next blood tests in 6 months. Anything kidney related takes time to show results, but a sudden decrease in egfr may be likely due to other things such as recent protein intake, or dehydration....if none of these are factors then best wait for the results of this drug over a longer period.
@@irfk4173 thanks, this is what happenned. My kidney improved again. :)
@@irfk4173did it improve?
What about for heart failure without kidney disease?
My Dr recommended it, but I'm still researching as a kidney transplant patient
So why is my Health plan telling me that there is a serious risk of taking Farxiga with CKD? I've noticed my GFR has declined since I started taking this 5mg dose as prescribed
I would speak to your doctor about that.
Doc. Can i take this with a ketoanalogue supplement ?
It shouldn't be an issue to take together but always check with your primary physician first . Thanks for watching and commenting
I’m taking farxiga and ketoanalogues
Would this benefit people on dialysis?
It won't reverse your kidney disease and get you off dialysis if that what you are thinking.
@@HealthyKidneyInc Wasn't expecting that (obviously).. I'm just wondering, if it is worth mentioning to my nephrologist, if it would benefit me in any way. What I meant was, would it maybe increase my GFR or urine output?
Hi, I don't think the medication will do that once you are on dialysis.
However, best to check with your nephrologist. You can always ask.
Robert
I took this med for a short time. My kidney function got worse so my kidney dr took me off of it.
I was looking at the first trials against diabetes, it doesn't lower A1C all that much, only around 1/2% ???
Its the renal protection portion we are discussing.
1-2% in points. Thus 8 A1C to 6 A1C.
I just want to know how many people loose weight and loose muscles and end up with high potassium in blood after take this Farxiga
Why would they end up with high potassium if you pee a lot with this medication, wouldn’t it help the opposite?
Stem cells are far better. Had stem cells put into my kidney. miraculous.
where, who, how?
Yes Tell us more pl
How
Please please please tell us where you received the stem cells?? I’m dying. I’m really really dying 😢😢😢😢😢😢
Kindly make a video on protein urea. If you have already done kindly share the link please
Hi Thanks for watching! I have several videos on this!! Check this one out! czcams.com/video/ukGTAKbH6iE/video.html