Most commonly Prescribed Psychiatric Medications: Duloxetine or Cymbalta
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- čas přidán 7. 07. 2021
- Cymbalta Commercial Link: • Cymbalta Commercial (r...
The marketing for Cymbalta went something like this, When your depressed who do you want to see no one, where do you want to go nowhere, depression hurts Cymbalta can help. This video covers the FDA approvals for Cymbalta, mechanism of action, and side effects of this commonly prescribed medication.
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It works fantastic for me and several other people i have referred it to for depression , rate it 10+ !! On it for years !! Thank you ❤️❤️❤️❤️
My husband is on cymbalta, I really don’t like what it has done to him. He’s so emotionless, and doesn’t have any care or fervor for anything anymore. He’s a different person and not in a good way.
blunted emotional responses can sometimes happen, I think carefully weighing the risks and benefits is a good idea.
My neurologist put me on cymbalta for my lumbar Radiculopathy. It’s been the only thing that has worked. I had a discectomy a few years ago but still have nerve issues. It totally helped me !
You're one of very few this drug helps. I hope you never have to taper off it.
I got fibromyalgia bpd anxiety depression it helps with all my illness 😂 im driving peaple crazy as makes me talk alot 😂😂 i feel better than i did in years its great 👍👍👍
How are you now
Maybe you got mania after tsking it.
I had neuropathy in my legs and everything and I tried other medications and nothing helped but I was prescribed Cymbalta and my leg feels so much better! I had a little insomnia but I'm working through that
I’m trying Cymbalta after no other depression meds have worked for me! I also take tranzene /Clorazepate which has had no side effects when I go off of them
Starting Cymbalta 20mg, 100mg Gabapentin in addition to my 100mg lamictal for treatment resistant MDD, anxiety, cPTSD, PTSD, insomnia and chronic pain with fatigue. Really hoping this recipe will help cuz I’m freaking mentally and physically exhausted 🙏🏼
How did it go?
How did it go friend?
Hello Doctor, I underwent cartilage surgery and it was pressing on the nerve roots. The treating doctor wrote me Duloxetine 30 times a day for a month. Does it have serious side effects during this period? Is it effective in treating neuritis? Thank you very much.
What I think would of great value from you dr Rossi,would be reviewing of these videos with what clinical knowledge you have enriched your views and therapeutical mind. Maybe do a case review that would be of educational value for medical students, GPS and nurses. We can all read leaflets and maybe pick up a textbook or two and maybe even a research article but what does dr Rossi thinks when looking at me or somebody else, there is no book that can get me the clinical day-to-day of why and how
Hii I am on 10mg aripiprajole.
Which antidepressant medicine have I to use for somatoform unspecified, ocd, Schizophrenia...
I am very sensitive to psychiatry medications. Which will more suitable?
Pristiq or Effexor or Cymbalta?.
Kindly reply I'm big fan of your's...
Hello Doctor. I am 63 & had a stroke March of 2022. My pain is controlled by Cymbalta (and my mood). The pain is better, BUT now I have SUCH STIFFNESS (aka spasticity?). I don't remember the spasticity before taking Cymbalta...Could that be a side effect of the drug? I have tried to get off the Cymbalta twice, each time the PAIN comes hack with a VENGENCE. My pain mgmt nurse keeps switching muscles relaxers, NONE have worked. Nothing seems to help. I am so confused 😔 I would appreciate ANY suggestions. Enjoyed this video (1st). Liked/subscribed.
This is the lady that just commented to you. (Mary) how will I know when you have commented back to me or when you will have a show on it?
Hi, I'm on Welbutrin and Cymbalta and I'm tapering very slowly off Cymbalta 30 mg. Im aware of the interaction between the 2 drugs but my Dr. wants me to continue. I have high BP and I feel it could be the cause.
Can cymbalta cause acne break outs or weight gain
Would love more expansion on topic of Fibromyalgia and also PMDD/severe PMS. I wish the impact psychiatric drugs had on hormones like estrogen/progesterone etc…was more mainstream knowledge.
sure this is something we can cover
As as fellow Fibromyalgia sufferer of 41 years, I will be 55 next month I hope you didn't touch it. This drug nearly killed me. It's not a joke. It shut down my bladder. Had I not gone to hospital, I would have died.
Cymbalta has been like manna from heaven for me!
If it's ever removed from the market I don't know what I'll do.
I tried many antidepressants be I finally found one that works.
Very cool, thanks for sharing your experience I feel like we need some more comments from people who have had success with medication. Cymbalta has many added benefits including improved cognition over other antidepressants. It’s one I use often and believe it has value as a treatment for depression. If you haven’t subscribed already, please do, and spread the word about what we are doing here.
@@ShrinksInSneakers I sure will! 👍👍
All drugs have side effects. A must-read is ANATOMY OF AN EPIDEMIC.
Yw joann , super duper late reply, can you elaborate on your cymbalta story please, i have depression, GAD + Social anxiety.
I was on 30mg for about 2 months and the doc just upped the dose for 60mg because i felt little calm but no motivation or improvement in anxiety or depression.
How long took to work?
Do you think Cymbalta will work well with Aripiprazole for mdd, am concerned about lowering energy levels during the day? The aim is to improve motivation and energy.
Did it work for you?
I have neuropathic pain on my face since I got dental implant placement in 2022. I used duloxetine around 7-8 months. It worked for my burning sensation for sure, was not 100% but still good. But lately they increased my dosage from 30mg to 90 mg and I got crazy. I wasn’t me any more. It took me to a zombie zone. OMG my brain was blowing. I’m no longer taking this patient killer anymore! Pardon pain killer 😒
My Dr just prescribed this for me 30mg but I also take a pain killer prescribed by same Dr..not methadone but is a controlled medicine....is this safe? Dr says of course it's safe, pharmacist said be careful about the cns affects of both meds but I don't see anything in my own research that says it has an interaction on the cns like a morphine or similar drug might have. Can you offer insight on this? I woukd be taking it for pain management and anxiety and depression caused from the pain and discomfort I deal with.
It really depends on the pain medication being used. The CNS depressant effects comment will come up as an interaction when combining these classes of medication but it’s hard to say if it’s relevant or not unless you check it. You can use this site to check reference.medscape.com/drug-interactionchecker Hope this helps, if you haven’t subscribed to the channel please do and spread the word about the community we are building here.
Thank you for this. Based on the half life, for GAD, would you suggest 30mg once a day or 20mg twice a day?
Can it be prescribed alongside bupropion to help offset the sleepiness?
Based on the half life you would split the dose. Although many people dose it once per day and I have not seen a significant differnace in the effect either way. There is some risk of increased blood levels and more side effects when these two medications are combined. Bupropion is a 2D6 inhibitor and cymbalta is metabolized by 2D6. It can be used but dose adjustment is needed and you need to watch for increased risk of seizure as well. Hope this helps, if you haven't subscribed please do and spread the word about what we are doing here.
Can you do a video about using cymbalta for anxiety & depression while also using methadone. My doc knows I'm on the methadone program and recently prescribed me cymbalta but I don't feel right. I feel really fatigued, foggy head, almost feel like its making my methadone not work as well. Its really weird and I dont like it. My doc is not knowledgeable so please don't say "ask your doc" i want to hear your take on it. I have already stopped the cymbalta because I dont feel its safe for me to continue but I really would like to hear from anyone who has knowledge. Btw I was only on it for 5 days at 30mg before I stopped otherwise I'd of had my doc help me stop.
Sure, we need to think about drug interactions. Methadone and Cymbalta do interact, and methadone can increase blood levels of duloxetine when the medications are combined. This may be the cause of your adverse side effects, although you were on a low dose, it may have been much higher due to the interaction, and this is because duloxetine is metabolized by CYP2D6 which methadone is a substrate for and may inhibit as well. Basically, you had higher serum levels of duloxetine due to the interaction worsening the side effects. I would have started with one of the more traditional SSRI like Lexapro in this case, the side effects are mild, and it works well for depression and comorbid anxiety. It still has some risk with methadone but much lower than the risk with Cymbalta. Hope this helps clear things up, appreciate the comment
Hi my Doctor started me on this 2 days ago. I've spent the 1st two days in bed completely exhausted....is this within normal boundaries? I'm not very keen on Antidepressants but im at the point where I need to try. I'm doing 30 mgs a day for a week then 60 mgs after a week.
This is not medical advice you should always talk to your doctor, this is general information for educational purposes only. Sedation is a potential side effect, the way I usually get around this is to have my patients take the medication at bedtime when feeling tired is a goo thing. Many people acclimate to the medication over the course of 4-6 weeks but I would talk with your doctor if it persists or interfere significantly with things like driving. If you haven't subscribed to the channel please do, and spread the word about what we are doing here.
One of the many meds I tried before finding the right combo and even though it did work to a certain extent, I had bad issues in terms of the urinary retention side effects so was eventually moved on with Californian rocket fuel haha. Also possible video idea as i haven't found much info on it but ive found the withdrawals seem to be worst with snri's like Cymbalta, venlafaxine then the other classes of anti depressants?
Also are you able to cover the medication pregabalin/Lyrica? It seems to be helpful for some psychiatric conditions but can be abused fairly easily unfortunately.
Withdrawal is known to be worse for venlafaxine specifically. I do not think an exact mechanism has been discovered for these withdrawal symptoms as of yet. I try to use extended release or avoid venlafaxine if possible because of this and the increased risk of death in overdose.
@@ShrinksInSneakers Also I've been curious as to why some studies and general information on anti depressants will sometimes call the withdrawals "discontinuation disorder".
Cymbalta cause urine retention?
After cold turkey can it cause frequent urination?
I am prescribed cymbalta for fibromyalgia but so worried to start as reading lots of Negative sideffects and how tough is the withdrawal like an opioids 😐
ME TOO! i'm so scared i went back and my doc said
"look.. internet is always going to say negative things but can i ask you did you see any good comments about the medicine?'
i said "well yes i did"
so i think sometimes you just gotta trust your doctor.
Have you reviewed the drug Clorazepate
I have not, It's not a common medication that I use but if there is enough interest I can talk about it.
I have restless leg syndrome, cymbalta sure helped me.
Glad to hear you had a positive outcome
id like to ask you a question i've suspected i had some sort of RLS since i was a teen. does it feel like a annoying tickling sensation kinda in the calves and if you keep still the sensation becomes worse until you have to move your legs or massage them with your hands? that is what i experience. also i only have this issue when i am sleep deprived. like pulling a all nighter or barely getting any sleep. and i'm glad cymbalta has helped your RLS.
Which is the best SSRI for IBS ? Plz make a video on it
no problem
I have agoraphobia. Which medication would help?
Doc, I really appreciate your informative videos! 😁Would you hate me if I wince at how you pronounce "ven-LA-fax-ine" as "ven-el-fax-ine?" 😖🤔🤐😜😩🤯
LOL, not OCD, right?!? 😳😬🙄🤦♀️🤣
You are not the first person to point that out, I'm working on it 😀All I can say is can't we just make these medication names a little easier to say. Appreciate the comment
@@ShrinksInSneakers LOL, thanks for not taking offense, I really enjoy your work! 🤣😉
@@Deba7777 It's all good just know it's a work in progress 😁
Would the blocking of dopamine reuptake effect someone with adhd? Or just in general? Could that alone have the potential to cause depression?
Blocking dopamine and noradrenaline is actually the mechanism of common ADHD medications. Too much dopamine wouldn't directly cause depression, could cause anxiety, impulsiveness or at extremes psychosis though
Why done you look into the camera?
Does this help ptsd ?
It's not FDA approved for PTSD only sertraline and paroxetine. The VA recommends sertraline, paroxetine, fluoxetine or venlafaxine. I think it could potentially help but IMO psychotherapy is best for PTSD in combination with one of the above medications. Hope this helps
I was taking this stuff when it was new (and very $$$) in college and going through a bad episode. Doctor couldn’t seem to give me enough of the stuff to do anything. Years later I find out smoking cigarettes makes it drastically less effective. Sooo much money and time wasted haha
Tardive dyskinesia?
I’ve Never seen a case of TD with this medication, but there is one case report that supposedly correlated duloxetine with dyskinesia. This is only a case report and lowest form of evidence, and dyskinesias can develop for other reasons besides medication. In fact, TD and other dyskinesias were described in schizophrenia long before medications were available. Hope this helps, if you haven’t subscribed to the channel yet, please do, and spread the word about what we are doing here.
I take cymbalta for lower back pain radiating to my foots ( sciatica - probably from overtraining abs ) 60mg a day.. Despite i dont suffer depresion - it make me feel better ( more energy) , even kinda like you are on mini speed dose .Painkilling effect is like dental local anastesia " freezing & numbness" in all body . Enlarged eye piupils also.. noticed...Scared out s-ht of me when I realised it can make your liver done.😱 I dont know...🥴?
It can be helpful for neuropathic pain. As far as the liver issues are concerned I would say unless you are compromised from an existing liver disorder or drink alcohol excessively it's not a major concern but as always run it all by your doctor. If you haven't already please subscribe to the channel and spread the word about what we are joining here.
@@ShrinksInSneakers Thank you sir . Helpfull info.
@@LucyFre thanks appreciate the support
@@ShrinksInSneakers You welcome sir.
Wow I have sciatica and depression will this help with both that'd be amazing
Duloxetine should be OFF the market! The Akathesia I got through, but I wasn't prepared for urinary retention to happen! Now, I'm fighting to reverse that asap as I refuse to live with that. Has ANYONE else had this side effect??
@Chief Sitting American rude much? Not just me. Too many people go thru this. I work in Pharmacy, so I see it a lot.
Some people can have urinary retention. Then again, it might help people who have stress incontinence. Basically, what is for some a side effect can for others be a therapeutic effect. And it's this way with many medications - does good for some, causes trouble for others.
@markus4698 definitely NOT the case with Duloxetine. It's poison to millions and millions. Look at the lawsuit against Cymbalta.
This guy is hot 🔥🥰
Greetings from France 🇫🇷
I have undifferentiated connective tissue disorder, adhd (non-attentive type) controlled high pressure, anxiety, depression. I'm 65yrs old. List of meds. I know it's alot but it's worked for appox 20 years. I was falling apart before I got on adderall 25 xr mg 1 daily, 1 adderall 25 ml. Short acting, 1 70 mg vyvance, daily, (Cymbalta 2 60 mg & pantroprazole SOD EC TB 40 MG X 2 DAILY (upset stomach everyday) & 40mg for the undifferentiated connective tissue) lamotrigine 25MG, 3X DAILY. compounded testosterone and estrogen for well being. A tiny bit of trazadone for sleep about 5 mg from 50mg broken tablet. Everything keeps me functioning except I'm postmenopausal and I think adderall doesn't work as well these days. Med.s go in and out of my body quickly. I know it's alot, I'm balanced for about 20 yrs. I would like to try to go off some of my rx. But I know I would go back to very disorganized mentally and physically. Have any idea of how to do this without pain and agony? I don't want to be disorganized again. I know of course I could talk with my dr.s. I know I need a Dr's help. It seems too hard for me to just go down in meds by my self. Thank you.