What is LGI1 Antibody Encephalitis?

An overview of LGI1 Antibody Encephalitis by Associate Professor Sarosh Irani, Head of the Oxford Autoimmune Neurology Group
This expert talk has been produced for World Encephalitis Day on 22nd February, 2020.
If you would like to find out more about World Encephalitis Day, visit www.worldencephalitisday.org
If you have been affected by encephalitis and would like to become a member of the society, you can sign up here (membership is free and global): www.encephalit...
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[@stevenbell12]

This video is so understandable! Thank you.
I was diagnosed with this in December 2022. So far there doesn't seem to be cognitive or memory loss symptoms. So far, at its worst, I experienced a seizure every 4 minutes. A few days after IV Infusion of steroids (with continual, tapering oral steroids) I've only experienced 4-5 weak episodes a day. I'm encouraged. Again, thank you for the explanations.

[@babyguinguin]

I was diagnosed towards the end of Nov 2022 and spend almost 1 month plus in the hospital during my first admission. Then I got a 'break' for close to 2 weeks before having my 2nd attack again. I don't remember any of that nor my previous hospitalization and certain parts of my memory.
I'm currently on 12 types pills inclusive of medication. Most of the time I hv issues of remembering things. I'm currently on a 4 Cycle medication plan whereby 1 cycle lasts for 4 weeks with bi-weekly IV medication of Rituxinab and methylprednisolone then followed by a 6 month break whereby I come in once a month for my IVIg-1 medication.
At the end of of the 6 months, Cycle 2 starts and the whole process repeats itself until 4 Cycles are completed. There is no 100% successful recovery as I was told but it does help with the quality of life.

[@jesuslovesyou.777]

Thank you for your help

[@encephalitisinternational]

Thank you for watching, Jamie!

[@zarahlibese2890]

Hi, am just watching your clip about Encephalitis beside my sister's hospital bed, thanks in advance

[@encephalitisinternational]

We are so sorry to hear about your sister Poulette. You are not alone - we are here for you. Please don't hesitate to get in touch at [e-mail], or call us on [phone] with any questions you have.

[@warisbaba7869]

can we expect a permanent treatment in future with the discovery of HLA molecule?

[@engysh425]

he says people coming to our clinic..... may i ask which clinic or their contact

[@encephalitisinternational]

Thank you for your comment, Engy. Sarosh is the head of the Oxford Autoimmune Neurology Group. The last card on this video is a link to their website (click the (i) icon on the top right hand side and scroll to the bottom), or you can find the site here: www.ndcn.ox.ac.uk/research/autoimmune-neurology-group

[@warisbaba7869]

do patients return to their normal self after treating the disease.

[@encephalitisinternational]

Thank you for your question, Waris. Some people recover from encephalitis with no consequences, in some people nerve cells in the brain may be damaged or destroyed by the inflammation. The resulting damage is termed an acquired brain injury (ABI). The degree and the type of damage vary according to the cause of encephalitis, the severity of the inflammation, the area of the brain affected and any delay in administering the appropriate treatment. You can learn more about the after-effects of encephalitis here: www.encephalitis.info/encephalitisafter-effects-recovery-and-rehabilitation

[@warisbaba7869]

@@encephalitisinternational thankyou for your time 👍