I'm treating my depression with psychedelics and I can say DMT treatment is way different than Psilocybin. With DMT you come back remembering almost nothing, whereas with psilocybin you have time to process. Both of them have positive effects in different ways (my friend reduced 95% her alcohol consumption and 65% tobacco after a 30 min DMT trip), but the real long-term life-changing effects come with psilocybin, ayahuasca or LSD. In short, DMT is like restarting your computer (it fixes some stuff quickly) whereas Psilocybin, Ayahucas and LSD are like defragmentation (long duration, more fixes). Be safe when using them! I've been reading books and scientific papers for months, these are not party drugs. Mush love 🍄❤️✨
@@PsychiatrySimplified I have 4 doctors that I keep in touch: general practitioner, nutritionist, psychiatrist and a therapist. The rituals are all done by me with my brother present as a sitter. Magic mushrooms are legal in Brazil, but therapy isn't, so instead of looking for a underground psychedelic therapist, I become my own =)
I suspect the pathways of successful psychedelic psychotherapy for Major Depression and PTSD includes sustained optimization of the dynamic balance of pro-inflammatory and anti-inflammatory influences within the brains glial cell populations. Measures of neuroinflammation would be interesting outcome measures potentially expanding our Body-Mind modeling knowledge base. Comments?
It is mentioned that during these sessions people experience the trauma which has lead to their depression. Having grown up during the 1960s & 1970s, this experience seems all too familiar with those folks who said they experienced a Bad Trip. It was that the drug they took was bad but, that their experience was traumatic because of some issue in their lives. Personally, I've had trauma in my life, even before I took Psychedelics but, I never had a Bad Trip.
It's also worth noting that what Prof. Nutt said regarding this point wasn't particularly revelatory. It is frequently discussed in underground psychedelic culture that 'bad trips' are often the most insightful and tend to cause the greatest positive changes to people's lives. Of course, if you're approaching these drugs recreationally then that might not be what you're looking for. But I do think we need to be very careful about how we define 'recreational'. Someone taking mushrooms once every 6 months at home with a few trusted friends, and using that as an opportunity to reflect on their lives, is distinctly different from someone using LSD or MDMA every couple of weekends in a rave environment. Since we are defining 'recreational' as 'non-clinical' use, we need to be mindful that people using these drugs for therapuetic purposes outside of a clinical environment as still considered 'recreational' users, even if they have no intention of enjoyment.
Great interview. Thanks. Wish we could have access to these therapies. Enough with the mostly inefficient bullshit of the usual psychological treatments.
I take SSRIS and I’m tripping while watching this lmao, LSD does work i just take a days break from the SSRIS then resume. DX of PTSD from childhood, ADHD, major depression, bipolar II, anxiety, and LSD/MDMA/Psilocybin/Weed works miracles for my mental health and growth, ability to self reflect and make better patterns, discover empathy and love for myself, and also be accountable for bad behaviors and thoughts my mental illnesses have enabled. I really think if people are open minded and their brain chemistry can handle it then these drugs can be wonderful tools.
I’ve been on and off weed for a while it’s amazing how effective it is.. i got on weed to make better decisions too.. i had to quit tho because it made my eye bags horrible almost worth it tho
I wonder if Dr. Nutt has anything to share regarding psilocybin and the reduction of brain inflammation , which I believe has been floated as a possible factor in depression .
There is some.evidence for Psilocybin as anti-inflammatory properties although it's not used as main stream treatment for this or for neuronflammation. We covered neuro inflammation in some detail in this video - czcams.com/video/TobQ0wMgkZs/video.html
what is the high dose he uses in the pscilocybin and psycotherapy study? i know he said hes doing one now with 1, 10 and 25 but didnt catch the significant dose in his other study
30 mg has been used inRCT in cancer patients - Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial - Griffiths et al
I need yur help somuch. I have such terrible depression, i cannot beleive I am born again into this each day and cry and cry and cry, srri’s gag you so you feel everything but cant express it, other drugs dont work yet they wont prescribe anything alternative.
Would the disease theory of addiction explain why football players who are addicts, like Maradona, George Best or Wayne Rooney, don't pass the ball selfishly, cheat, hurt other players, get expelled by the referee? The only common denominator between all addicts of any social background and distinction is that they are notorious liars. Addiction affects predominantly young healthy criminals. I have been trying to have the discovery of the nature of addiction known for years to end the war on drugs. I would like to help you as a recovering addict and psychologist. Addiction is the psychology of a liar, drugs don’t cause addiction and only liars get hooked and only honesty gets freedom. The tragedy of addiction is children who revenge a childhood hurt, or trauma, against their parents learning from example. Addicts don’t forgive, are needy of attention that steal from others, and have secrets that tell in AA meetings to reveal who they truly are to take off the mask and heal, ending the identity deception. Liars bring up liars, addiction runs in families. Parents hurt their children and children retaliate becoming victims of themselves to conceal the hatred and hurt others. I am alone socially ostracised by liars paying the price for being honest. I can prove my claim that the obvious truth is addiction is the psychology of a liar dropping mortality rates when my theory is known.
This looks like a parody of a real interview whilst providing real content, even though the presentation is overly verbose with superfluous accentuations.
@@FuncraftVideos education mainly. We have done a number of videos and are now planning to do a series of videos with clinicians, experts etc ; a different way of learning. Text books don’t always encompass the clinical experience aspect and sometimes the story telling aspect of interview may allow for better learning. Our view ofcourse
I suspect the pathways of successful psychedelic psychotherapy for Major Depression and PTSD includes sustained optimization of the dynamic balance of pro-inflammatory and anti-inflammatory influences within the brains glial cell populations. Measures of neuroinflammation would be interesting outcome measures potentially expanding our Body-Mind modeling knowledge base. Comments?
Good comment. There is evidence of increasing BDNF levels as a.potential mechanism of action for paychdelics which is also a news discovered target receptor for BDNF that is proposed to be the MOA for common Antidepressants . BDNF is Neuro protective and protects against neuroinflammation - we may know more over time.
I suspect the pathways of successful psychedelic psychotherapy for Major Depression and PTSD includes sustained optimization of the dynamic balance of pro-inflammatory and anti-inflammatory influences within the brains glial cell populations. Measures of neuroinflammation would be interesting outcome measures potentially expanding our Body-Mind modeling knowledge base. Comments?
I suspect the pathways of successful psychedelic psychotherapy for Major Depression and PTSD includes sustained optimization of the dynamic balance of pro-inflammatory and anti-inflammatory influences within the brains glial cell populations. Measures of neuroinflammation would be interesting outcome measures potentially expanding our Body-Mind modeling knowledge base. Comments?
I suspect the pathways of successful psychedelic psychotherapy for Major Depression and PTSD includes sustained optimization of the dynamic balance of pro-inflammatory and anti-inflammatory influences within the brains glial cell populations. Measures of neuroinflammation would be interesting outcome measures potentially expanding our Body-Mind modeling knowledge base. Comments?
I'm treating my depression with psychedelics and I can say DMT treatment is way different than Psilocybin.
With DMT you come back remembering almost nothing, whereas with psilocybin you have time to process. Both of them have positive effects in different ways (my friend reduced 95% her alcohol consumption and 65% tobacco after a 30 min DMT trip), but the real long-term life-changing effects come with psilocybin, ayahuasca or LSD.
In short, DMT is like restarting your computer (it fixes some stuff quickly) whereas Psilocybin, Ayahucas and LSD are like defragmentation (long duration, more fixes).
Be safe when using them! I've been reading books and scientific papers for months, these are not party drugs.
Mush love 🍄❤️✨
Thank you for sharing your personal experiences. Is this with psychotherapy under medical supervision?
@@PsychiatrySimplified I have 4 doctors that I keep in touch: general practitioner, nutritionist, psychiatrist and a therapist. The rituals are all done by me with my brother present as a sitter. Magic mushrooms are legal in Brazil, but therapy isn't, so instead of looking for a underground psychedelic therapist, I become my own =)
@@opedromagico I've had a very similar experience to yours but in Australia. My doctors are aware and my dad is my sitter ❤
What a wonderful interview. How small some people think. What a shame.
10:52 - The unknown word he says is MAOi, monoamine oxidase inhibitor.
Excellent video gentlemen . Much information very well presented : good questions and fascinating responses . Thank you !
Thank you for your feedback
Brilliant interview Sanil.
Thank you for your feedback 🙏🏼
So informative and timely. Thanks again
Thank you for the feedback 🙏
Thank you both for this interesting content ❤️❤️
Thank you for the feedback 🙏
I suspect the pathways of successful psychedelic psychotherapy for Major Depression and PTSD includes sustained optimization of the dynamic balance of pro-inflammatory and anti-inflammatory influences within the brains glial cell populations. Measures of neuroinflammation would be interesting outcome measures potentially expanding our Body-Mind modeling knowledge base. Comments?
It is mentioned that during these sessions people experience the trauma which has lead to their depression.
Having grown up during the 1960s & 1970s, this experience seems all too familiar with those folks who said they experienced a Bad Trip. It was that the drug they took was bad but, that their experience was traumatic because of some issue in their lives. Personally, I've had trauma in my life, even before I took Psychedelics but, I never had a Bad Trip.
It's also worth noting that what Prof. Nutt said regarding this point wasn't particularly revelatory. It is frequently discussed in underground psychedelic culture that 'bad trips' are often the most insightful and tend to cause the greatest positive changes to people's lives. Of course, if you're approaching these drugs recreationally then that might not be what you're looking for. But I do think we need to be very careful about how we define 'recreational'. Someone taking mushrooms once every 6 months at home with a few trusted friends, and using that as an opportunity to reflect on their lives, is distinctly different from someone using LSD or MDMA every couple of weekends in a rave environment. Since we are defining 'recreational' as 'non-clinical' use, we need to be mindful that people using these drugs for therapuetic purposes outside of a clinical environment as still considered 'recreational' users, even if they have no intention of enjoyment.
Great interview. Thanks. Wish we could have access to these therapies. Enough with the mostly inefficient bullshit of the usual psychological treatments.
I take SSRIS and I’m tripping while watching this lmao, LSD does work i just take a days break from the SSRIS then resume. DX of PTSD from childhood, ADHD, major depression, bipolar II, anxiety, and LSD/MDMA/Psilocybin/Weed works miracles for my mental health and growth, ability to self reflect and make better patterns, discover empathy and love for myself, and also be accountable for bad behaviors and thoughts my mental illnesses have enabled. I really think if people are open minded and their brain chemistry can handle it then these drugs can be wonderful tools.
I’ve been on and off weed for a while it’s amazing how effective it is.. i got on weed to make better decisions too.. i had to quit tho because it made my eye bags horrible almost worth it tho
I wonder if Dr. Nutt has anything to share regarding psilocybin and the reduction of brain inflammation , which I believe has been floated as a possible factor in depression .
There is some.evidence for Psilocybin as anti-inflammatory properties although it's not used as main stream treatment for this or for neuronflammation. We covered neuro inflammation in some detail in this video - czcams.com/video/TobQ0wMgkZs/video.html
what is the high dose he uses in the pscilocybin and psycotherapy study? i know he said hes doing one now with 1, 10 and 25 but didnt catch the significant dose in his other study
30 mg has been used inRCT in cancer patients - Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial - Griffiths et al
I need yur help somuch. I have such terrible depression, i cannot beleive I am born again into this each day and cry and cry and cry, srri’s gag you so you feel everything but cant express it, other drugs dont work yet they wont prescribe anything alternative.
Apologies, that was a test, not a sarcastic comment
How to manage antidepressant withdrawal symptoms? Suggest some natural remedies . Very allergic to drugs
Thanks to Phillip_shrooms on Instagram. I'm using this instead of adderal and antidepressants, It's so helping me treat my depression and anxiety.
How can we get in touch for treatment from these individuals
i wish i could go on one of these trials
Psychedelics??, 👆👆Man's the realest lately 🍄 💊🍄🍫💯🔌
I got guidelines from 👆👆him, Microdosing stops depression,ADHD and PTSD. He is my supplier 🍄 💊🍄🍫💯🔌
Would the disease theory of addiction explain why football players who are addicts, like Maradona, George Best or Wayne Rooney, don't pass the ball selfishly, cheat, hurt other players, get expelled by the referee? The only common denominator between all addicts of any social background and distinction is that they are notorious liars. Addiction affects predominantly young healthy criminals. I have been trying to have the discovery of the nature of addiction known for years to end the war on drugs. I would like to help you as a recovering addict and psychologist. Addiction is the psychology of a liar, drugs don’t cause addiction and only liars get hooked and only honesty gets freedom. The tragedy of addiction is children who revenge a childhood hurt, or trauma, against their parents learning from example. Addicts don’t forgive, are needy of attention that steal from others, and have secrets that tell in AA meetings to reveal who they truly are to take off the mask and heal, ending the identity deception. Liars bring up liars, addiction runs in families. Parents hurt their children and children retaliate becoming victims of themselves to conceal the hatred and hurt others. I am alone socially ostracised by liars paying the price for being honest. I can prove my claim that the obvious truth is addiction is the psychology of a liar dropping mortality rates when my theory is known.
We don't want to deal with that that's not the path
This looks like a parody of a real interview whilst providing real content, even though the presentation is overly verbose with superfluous accentuations.
Thank you for your feedback.
@@PsychiatrySimplified If you don't mind me asking, what is your motive for doing these interviews?
@@FuncraftVideos education mainly. We have done a number of videos and are now planning to do a series of videos with clinicians, experts etc ; a different way of learning. Text books don’t always encompass the clinical experience aspect and sometimes the story telling aspect of interview may allow for better learning. Our view ofcourse
That's hilarious... Overly verbose with superfluous accentations 😄😂🤣😅
I suspect the pathways of successful psychedelic psychotherapy for Major Depression and PTSD includes sustained optimization of the dynamic balance of pro-inflammatory and anti-inflammatory influences within the brains glial cell populations. Measures of neuroinflammation would be interesting outcome measures potentially expanding our Body-Mind modeling knowledge base. Comments?
Good comment. There is evidence of increasing BDNF levels as a.potential mechanism of action for paychdelics which is also a news discovered target receptor for BDNF that is proposed to be the MOA for common Antidepressants . BDNF is Neuro protective and protects against neuroinflammation - we may know more over time.
I suspect the pathways of successful psychedelic psychotherapy for Major Depression and PTSD includes sustained optimization of the dynamic balance of pro-inflammatory and anti-inflammatory influences within the brains glial cell populations. Measures of neuroinflammation would be interesting outcome measures potentially expanding our Body-Mind modeling knowledge base. Comments?
I suspect the pathways of successful psychedelic psychotherapy for Major Depression and PTSD includes sustained optimization of the dynamic balance of pro-inflammatory and anti-inflammatory influences within the brains glial cell populations. Measures of neuroinflammation would be interesting outcome measures potentially expanding our Body-Mind modeling knowledge base. Comments?
I suspect the pathways of successful psychedelic psychotherapy for Major Depression and PTSD includes sustained optimization of the dynamic balance of pro-inflammatory and anti-inflammatory influences within the brains glial cell populations. Measures of neuroinflammation would be interesting outcome measures potentially expanding our Body-Mind modeling knowledge base. Comments?