Lineweaver-Burk Plot and Reversible Inhibition

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  • čas přidán 13. 03. 2015
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      Except the Khan Academy video on this subject is completely wrong. AK's is perfect.

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  • @TheRealPetoria
    @TheRealPetoria Před 9 lety +154

    Underrated videos. Thank you for breaking all this material down and explaining it so thoroughly at the same time. You are an excellent teacher! As a 1st year pharmacy student, I can attest to these videos helping with graduate level biochemistry. Keep making these videos! I hope you put some up about metabolic pathways and electron transport chain, if you haven't already. Thank you so much.

    • @AKLECTURES
      @AKLECTURES  Před 9 lety +16

      +xJet321Xx Already have those. :)

    • @violinsheetmusicblog
      @violinsheetmusicblog Před 8 lety +1

      You guys still learn this in grad school? I swear this is like my 3rd class that covers this. (and I still keep forgetting it lol)

    • @hajiradurrani5730
      @hajiradurrani5730 Před 3 lety +1

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    • @41kmkharshnaik71
      @41kmkharshnaik71 Před 3 lety

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    @xentippy Před 8 lety +47

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      @AKLECTURES  Před 8 lety +27

      Aww Jessica, thanks for the kind words! Great to hear you're going back to school; its definitely not easy to get back in the grind but its going to be worth it at the end! Keep up the hard work and let me know how it goes!

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    @mikewysotski1959 Před 8 lety +40

    Your lectures are outstanding. Chemistry professors should learn your delivery/presentation style.

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    @camillam.2364 Před 7 lety +4

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    @larapaxton8423 Před 5 lety +2

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    @fawadkhan1337 Před 4 lety +8

    "in just a few moments" magical words

  • @akashbansod4546
    @akashbansod4546 Před 10 měsíci

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    @nazlimcfian Před 6 lety

    in all those other videos that i watched about lineweaver they used to clean the plot to explain the other one but as you kept all of them on a same single board it helped me to understand all and gave me an apportunaty to be able to visualize and compare them, million thanks .

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    @Alex-wq9hi Před 4 lety

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      @AKLECTURES  Před 8 lety +2

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    @deepankerbisht9356 Před 6 lety

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    @sarmenhakopian4532 Před 6 lety

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    @bethelsamson7434 Před 3 lety

    this was incredible thank you

  • @YWoappi
    @YWoappi Před 9 lety

    Great explanation. I finally understand this.

  • @johnwise6914
    @johnwise6914 Před 8 lety

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  • @B3bita1215
    @B3bita1215 Před 6 lety

    Thank you sosososoo much sr. I now understand why Km is smaller for the uncompetitive inhibitor. Finallyyyyyyy..... I'm soooo happy :)
    :)
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    Once againThank you soooooo much :)

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    @Bankaban27 Před 7 lety +2

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    @user-ru8yp4pc4k Před 9 měsíci

    Thank you
    really great explanation

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    @davidsanchez1018 Před 6 lety

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    Cheers!

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    @nahidAHlaskar Před 7 měsíci

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    @superoxidedismutase5757 Před 6 lety +102

    7:24 "we can calculate what the _slope_ is" ROFL

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    @laibakhan9177 Před 4 lety

    OMG ..it was really helpful..Thank u Sir

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    @Sarah-co5uu Před 3 lety

    wowww. it was great. thank you

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    @hajiradurrani5730 Před 3 lety +1

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  • @jasminemh5664
    @jasminemh5664 Před 6 lety

    I'm from Jordan and I love you're explanation I'm in Jordan university of science and technology

  • @melidiamar
    @melidiamar Před 7 lety +1

    Muchas gracias, no encontré un video en español que me ayudara a entender por qué cambia la ecuación Michaelis y Mentel, a hacer una gráfica lineweaver burk y a interpretarla. Thanks. Your pronunciation was very clear so the subtitles recognition let me know what you were saying. I´m suscribing.

  • @rukaiyatasnim4799
    @rukaiyatasnim4799 Před 2 lety

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  • @Vatierville
    @Vatierville Před 8 lety +3

    I find your lectures extremely helpful and informative :-) Where do you get your information regarding the topic? Do you have any references for your resources? Regards, Lewis!

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    @vedastondayalinze7975 Před 7 lety +2

    your so good teacher

  • @GDunnPT
    @GDunnPT Před 5 lety

    Amazing amazing video..

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    @nicolas.leger3 Před 6 lety +1

    Thanks Dude!!!!!!

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    @mikehsieh0103 Před 5 lety

    I respect you seriously

  • @MildMinimalist
    @MildMinimalist Před 7 lety

    Fantastic video - thank you! Question though: how does catalytic efficiency change for each of the 3 reversible inhibitors? It would make sense for it to decrease (since they are inhibitors), but I have a question.
    Since catalytic efficiency is defined as Kcat/Km, I would assume that a competitive inhibitor would decrease catalytic efficiency because Km increases and Kcat is the same (since Kcat = Vmax/[total enzyme] and Vmax & [total enzyme] don't change). But for an uncompetitive inhibitor, both Km AND Kcat decrease. Wouldn't this not change the ratio of catalytic efficiency?

  • @zahra1455
    @zahra1455 Před 4 lety

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    @nimrahmalik2941 Před 4 lety

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    @---ev6xm Před 4 lety

    This guy is amazing

  • @parisak2432
    @parisak2432 Před 3 lety

    thank you very much indeed

  • @babylonianbarbell8541
    @babylonianbarbell8541 Před 6 lety

    Beautiful equation