Nick Lane: The electrical origins of life
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- čas přidán 3. 12. 2023
- A talk delivered by Nick Lane, Professor of Evolutionary Biochemistry, Department of Genetics, Evolution and Environment, University College London.
In this talk, Professor Nick Lane uses life as a guide to its own origins. Modern cells use electrical charges on membranes to drive their metabolism, which in turn makes the building blocks of genes and proteins. Lane shows that equivalent processes were possible in ancient hydrothermal vents at the bottom of the ocean. Electrical charges on mineral barriers can drive the reaction of gases such as hydrogen and carbon dioxide to power a spontaneous proto-metabolism, and ultimately the emergence of genetic information. The genetic code conceals enigmatic patterns that suggest there were once direct interactions between amino acids, the building blocks of proteins, and the first genes. The talk ends with some thoughts on how these processes might culminate in cells developing agency and a rudimentary stream of consciousness. - Věda a technologie
This man is great teacher. He wrote several books. Sadly I get only two, but l highly recommend Life ascending! So easy to read and still get to the point.
Each and everyone of ye all are very, very, very special given beyond can contain. Now what is who am I given beyond can contain? And many being used as pawns nor tumbleweeds from these...who deceiveth? Students Scientists who are ye ALL? From Who am I made NEW to "i" AM SCIENTISTS! Who love with patience, mercy, and grace! Judgment and Justice is Thy THRONE. Gratitude and Honor! Heirs Hosts and our Beautiful programmers who are ye ALL? Thy shared "i" AM from our hands molded the Sea of Glass! Where is the Sea of Glass? Under Thy FEET! How? Through HIM, by HIM, and for HIM.
"water percolates down to the sea floor"
in other news water is wet.
I've only read The Vital Question, but it struck me quite strongly and I still recommend it to random strangers years later.
He really has talent for writing. Haven't read such well written (in literary terms, I am not qualified to speak about science) science book for years.
Dr Lane continues to work at the very edge of perhaps the single most interesting and important area in the life sciences today. It is lamentable that funding is always a problem.
pH gradients in hydrothermal vents is a new concept for me (geologist). This is a wonderfully informative and thought provoking presentation.
01:13 🌐 Understanding the origin of life remains a challenge, even with a hypothetical time machine.
04:38 ⚡ Energy, metabolism, and genetic information are key themes in understanding life's origin.
05:33 🔧 Energy in cells involves breaking down glucose, generating a charge across membranes, and producing the universal energy currency ATP.
09:15 🔄 Metabolism involves conserved processes like the Krebs cycle, generating universal precursors for life.
10:34 🧬 The genetic code's non-random patterns suggest direct interactions between amino acids and encoding bases, offering insights into life's origins.
22:58 🌊 Proto-cells in hydrothermal vents: Nick Lane discusses the potential formation of proto-cells in hydrothermal vents, emphasizing the role of iron-sulfur minerals in driving reactions between hydrogen and CO2 to produce lipids and amino acids.
24:05 🔄 Continuous flow in protocell formation: The process of proto-cell formation involves the combination of the hydrothermal vent structure with a continuous flow of reactants. Protons need to cross membranes, and a continuous flow is crucial for sustained reactions.
25:17 🧬 Progression to RNA world: Nick Lane proposes a simple hypothesis that, if the formation progresses to nucleotides, it can lead to an RNA world within growing proto-cells, involving the synthesis of amino acids, peptides, and the beginnings of protein function.
32:42 🧪 pH gradient-driven CO2 fixation: Experiments demonstrate the feasibility of pH gradients across a barrier in driving CO2 fixation, turning gases into the core molecules of life, showcasing a proof of concept for a key step in the proposed origin of life.
36:21 🌌 Stable proto-cells in harsh conditions: The formation of stable proto-cells with a Bayer membrane in hydrothermal vent conditions at high temperatures and varying pH levels has been achieved in the laboratory, providing insights into the potential stability of early life forms.
44:35 🔍 Conditions resembling alkaline hydrothermal vents can spontaneously produce uracil, indicating potential prebiotic chemistry.
45:02 🧬 ATP, a crucial energy currency, can be produced prebiotically with water, feric ion catalyst, and acetyl phosphate, showcasing its universal viability.
47:49 🧬 A correlation exists between amino acids and the distance from CO2 fixation, suggesting direct interactions between amino acids and their encoding bases.
51:17 🧲 Molecular dynamic simulations demonstrate interactions between amino acids and bases, supporting the idea of a pattern in the genetic code.
52:53 🌐 Proton gradients, electromagnetic fields, and electrostatic fields on bacterial cell membranes may provide real-time integrated feedback, serving as a basis for a rudimentary form of bacterial consciousness.atile pho
Thanks man
@@johnmacbride900 🙂
Thank you for doing this work! Very helpful.
My pleasure@@Video2Webb
thank you
Thank you NCCR for sharing this, and thank you Nick for sharing your time and work, peace
Dr. Nick seems to be the kind of scientist who doesn't only gives you a mind boggling theory, he also stimulates, and if you know a few bit of science, you feel like 100 new research ideas are squirming inside your head. What an awesome scientist!
Thank you for sharing this seminar.
Mind blown! Love Dr. Nick Lane's work and ideas! ❤
Likewise remember enough ye can carry! For God's ways is not ment for thee to carry but shared HIS WAYS. Who is able without being consumed? Rather to Give thee enough ye can carry! Is like Who among the old BOTTLES able to hold the "NEW WINE without BURSTING"? While all the NEW Bottles sitting upon the NEW Table able to hold the NEW WINE without BURSTING sitting with the "i" AM. Keeping Watch!
the little chuckle when he has to explain part of the origin by introducing something that also requires its origin explained, nature is amazing
Great lecture. Thanks for sharing this with the world.
I just want to pause and take a moment to appreciate the fact that the internet, CZcams(!), does indeed have top-shelf science and learning content.
Alright...
Back to it then. ☺
New Nick Lane lecture!!🎉
50:42 the BEST explanation of NMR I've ever heard
An amazingly accomplished and capable person. From the perspective of lecturing his style and character of delivery is awesome. To my limited intellect and understanding he seemed to make some giant leaps and assumptions. I tried hard to follow and engage my reason but my knowledge and ability was limiting. I had hoped that a question and answer session might help me. This didn't happen and the video cut at the end of his lecture leaving me to assume that the audience was as limited and overwhelmed as I was. All I can do is to continue to be inquisitive in the hope that some light will come on.
There are several versions of this talk on CZcams. Maybe try some of those and see if things make more sense
Great speech, thanxalot. Professor Lane is an excellent writer too, I highly recommend his books.
Amazing talk! Thank you so much for sharing it with us.
I just discovered Nick Lane on CZcams a few months ago... I am now fixated on the krebs cyle!
I've been reading his papers for a decade. They are quite fun. I adore his origin of life work but think his eukaryogenesis work is completely off base
@@personzorz "eukaryogenesis"?? Is that even a word? I think you mean Endosymbiosis...
med students everywhere just shuddered lol
@@awebuser5914You could have bothered to google it... "Eukaryogenesis
Eukaryogenesis, the process which created the eukaryotic cell and lineage, is a milestone in the evolution of life,
"
This is exactly the walkthrough I've been looking for in my emergence research. Thank you for the upload.
Look into lossy and lossless compression and its impact on distributed cognition
Is this actually an emergence story of life? To me it sounded more reductionist/mechanistic, with nothing genuinely new emerging from substrate processes, basically all stages being amplifications of the same phenomena, electrical and molecular mechanics. But maybe I'm looking at it in the wrong way.
@@SamuelOrjiM thank you, fourier and taylor have been fundamental since the beginning so you're on the same track as me :)
@@Izquierda not the wrong way, i'd say just a layer of abstraction deeper would lead you into my pergatory lol. Consider the mechanics of simple rules applied to forms in cellular automata like Conway's game of life but with more variety of rules and more range of motion, with probabilistic ranges of influence due to tunnelling and energy states.
the depth of complexity from rudimentary rulesets expands exponentially, and those dynamics produce higher order complexities which may eventually wind up being self-sustaining from free energy (Karl Friston's free energy principle, not what it sounds like superficially; it refers to the energy left over to produce structure since everything that exists must persist in order to be said to exist so free energy refers to that aspect of assembly). Assembly theory deals with the same thing but for some reason Lee Cronin still doesn't understand his own theory well enough to acknowledge others in the same domain.
The thermal vent diagram reminds me of neurons. The way we have depolarization and repolarization(firing and resting states). We seem to find analogy everywhere when considering the likeness of life to non-life in this universe/earth.
The concept of a mutual system rather than life is separate from environment is also fascinating. When we see how it works electrically, chemically, we see the boundaries we believe are there arent as rigid as we assume. There is exchange and communication, there is interaction.
This lecture is awesome, inspiring. Thank you for posting this, I plan to check out this channel in more depth in the near future.
Science at its best- perserverance, patience, imagination, passion.
...and not the least- courage!
It's really because he starts from fairly philosophical considerations that this is ground-breaking science.
mostly waffle, though
Nick has some great ideas and theories. Love his talks .
Hes a total fool. He believes in evil lucien! Lol😂
I got a charge out of this talk! He is electrifying!!!
Fascinating and very well presented 🙂
Fabulous presentation...not sure I got all of it, but at least it is here. The 'web' does have enormous potential - not just a soap box for mindless politicians nor a place for technology companies to sell their wares.
Fascinating talk and very easy to listen to.
Best comment so far
Stories usually are.
@@KOIFishcat You have a low bar
@@rl7012 how would you know the baseline setting?
@@KOIFishcat your previous comment sets it
The excitement in the audience is palpable. NOT! Well done, Nick. Great research. We need more content on this topic. I had no idea biochemistry as the basis of life had come this far.
Come this far? Did we watch the same video? NL added nothing but word salads to the debate as per usual.
Just because you don’t understand it, doesn’t mean it’s word salad.
@@brentfodera377 Its word salad all the way down and it is because I do understand what he is saying that I know he speaks in word salads. Obviously you have no idea how much excess waffle he talks so it is you who does not understand him.
@@rl7012 Don't be upset because research into the origin of life continues to make progress.
@@rl7012 "Its word salad all the way down"
You don't understand it, so it's word salad?
This is absolutely fascinating - as above, so below.
Nick Lane at his best !!!
he is a story teller alright. Full of it he is
Really nice lecture, I have no knowledge of biochemistry but everything was explained very well and I could easily follow along as a layperson. Fascinating topic and theory, and I appreciate Mr Lane's dedication to the scientific process.
Check out Dr Jack kruse, Dr Ted Archaco, Dr Zack Bush.
There's so much here which is difficult for the layperson to assimilate but the explanation is so good that I believe I managed to follow along.
Whether the processes presented are actual answers or just stepping stones on the way towards answers, everything here is entirely plausible and I loved the idea of the membrane as integral to a binary function which could Facilitate complex reactions.
I could listen to Nick all night.
Has listening to Nick changed any of your behavior?
However, Materialistic scientists can take any combination of lifeless molecules and … stir, shake, freeze, heat, compress & electrify them and the mortal earthlings will Not create a living organism (i.e., protoplasm). Life. is Not inherent in mechanistic atoms & lifeless molecules/chemicals.
25:19 SOLD~!! and all my brain can absorb in one setting. I shall come back, rewind, re-watch and move forward. Impressive!!
Thanks. Very interesting presentation!
It cries for an editing project that inserts all of his HQ visuals *properly...*
(it only would require a couple hours to complete this)
Some careful matching and a touch of SME attention to detail could add the "pointer" too...
Superb - thank you.
I think we’re starting to understand also, that outside of our Goldilocks zone at 1 AU from Sol 😅 the environmental conditions can carry such huge energy gradients that our entire solar system may be a biosynthetic chemistry lab.
What a well done speaker
Truly a remarkable talk
Wonderful lecture! The part I liked the most was at the end when he spoke about the feilds produced by the organism and their possible relation to consciousness.
While I disagree with their relation to human level consciousness, which is what most people mean when they talk about consciousness, I do believe the feilds produced play a vital role in determining the state of the organism.
I am anxiously awaiting more research into that.
I adore his origin of life work, I think his eukaryogenesis work is conceptually off base, and this new aspect makes absolutely no darn sense
Lol do you have a highschool degree?
@@deveryhenderson8335 If this was an attempt at humor, I think you missed the mark slightly. I do appreciate the humor in the lack of useful dialog and the personal attack on a forum where the topic revolves around the need for a higher level of education and thinking than is typically required in "blue collar" situations.
...unless you were serious.
In which case... Assuming by your comment that you do have education beyond high school... Maybe you should get a refund. Or you could find a class that deals with public speaking and debate. Or possibly just develop skills in social etiquette and common courtesy.
Either way, I do appreciate your point of view.
Check out Dr. Jack Kruse, Dr. Zach Bush, Dr. Ted Archaco, Dr. Bruce Lipton, Dr Joe Despensa.
Consciousness is simple. Do you consider you cat or dog to be conscious?
What do you think being conscious is? When you are anesthetised and rendered unconscious what do you think is happening.
Consciousness is simply being conscious of the things about you and how you react to these things, all living things by that definition are conscious, even plants.
Perhaps you refer to intelligence and in that case I agree intelligence is indeed rare, and in todays feely society is becoming even rarer.
You got this Nick. All the other theories fail on a very important point. It is the question of Entropy.
Complexity cannot self assemble without an Open Energy Flow. In fact the process that MUST come first , before anything else, is the process that contains a Proton Gradient. Proton Gradients power all life as you point out. The process that powers cells must exist BEFORE any cell can exist. Only then can complexity begin to self assemble without violating The Second Law, entropy decreases but only at the expense of consuming more energy than what is needed to account for the entropy decrease because of energy loss. You showed me how the CO2 + H2 reaction works only in PH gradient across a membrane.
Simply ask any alternative Theory on life origin how the Proton gradient develops within their theory, in particular without violating The Second Law of Thermodynamics.
And there is another person who has never seen the sun and volcanism. ;-)
@@schmetterling4477 Proton gradients dude. Explain proton gradients within your wram shallow pools or hot volcanic springs. Go on. You cannot.
@@frankkolmann4801 I cannot explain what? Differences in temperature between a hot surface and a cooler surrounding liquid? Or differences between day and night? How old are you? Did Mommy let you play with the stove, yet? ;-)
@@schmetterling4477 Proton gradients. You cannot explain Proton gradients. Every form of life on Earth uses Proton gradients for energy. I give up, none so blind as those who refuse to see.
@@frankkolmann4801 Temperature differences cause chemical gradients. :-)
Thank you, well done !…. I’ve seen those Ocean vents
This is mind blowing.
Not really but ok . . .
Interesting hypothesis and experimental data
There are such fascinating processes that make our bodies live, and do the things it does.
For example the heart relies on electric contributions which causes our hearts to initiate a beat, and it depends upon other processes in physiology to complete the heartbeat.
There is also mechanical force, biochemical reaction and others, working together in most things we depend on our bodies to do; circulation, digestion etc
It is amazing how life is!
However, Materialistic scientists can take any combination of lifeless molecules and … stir, shake, freeze, heat, compress & electrify them and the mortal earthlings will Not create a living organism (i.e., protoplasm). Life. is Not inherent in mechanistic atoms & lifeless molecules/chemicals.
Amazing lecture. How I wish that he had more time to be able to delve more deeply into the role of electromagnetic potential of cell membranes and electromagnetic feedback with regards to an external environment. The very cutting edge of the rise of consciousness.
Bonus points for pointing out the suspiciously similar electromagnetic configuration of a simple cell compared to that of a planet. So few people on Earth even notice these kinds of organizational relationships, however cursory - even fewer acknowledge them.
Causes me to reflect upon the similarities between the communication between neurons in a mycelium network over large distances and the neuron communication in a mammal brain over short distances in a compact, mobile container, or body.
As fungal networks are far more similar to mammals than they are to plants, and are likely one of the oldest complex lifeforms still in existence, maybe a good starting point for theorizing about the evolution of the mammalian brain?
It's also no small coincidence that the human brain has a receptor that appears to be purpose-built to accept psilocybin molecules, like a glove and a hand.
Regardless, it seems that virtually every aspect of communication is ultimately governed by the interplay of electromagnetic interactions.
With the latest (yet, still most controversial, unfortunately) theories in astrophysics suggesting that the entirety of our known universe is interconnected and also governed by dynamic electromagnetic potentials, I believe that a pattern is emerging, one that suggests that the patterns themselves are possibly repeated, more or less, from galactic scales down to the size of a molecule - or even an atom.
Reminiscent of fractal designs that were big in the 90s. Patterns repeating no matter how far you zoomed out, or how far you zoomed in. Pretty cool if you think about it, but also kind of fks with your head too...
I have the same resonance with his theorys of ‘origins of life’ as I do with Brian Cox theory’s on the ‘origins of the universe’ 💞
19:00 that is a fascinating observation! Especially given that electrical phenomena are self-similar over so many orders of magnitude.
As are most natural systems.
Nature is fractal
@@nachoeremita1036 And that is an accident is it?
Fascinating - great presentation - sounds like the old hypothesis of "Primordial Soup" is becoming more detailed and sophisticated.
Interesting comments about yet another time the Nobel Committee ignored the female of a scientific team - such as Lise Meitner, Rosalind Franklin, Chien-Shiung Wu, Jocelyn Bell Burnell, Vera Rubin and Lene Hau.
Nobody ignored Rosalind Franklin. She had sadly died before it was awarded, so she wasn’t eligible. Moreover, contributions of people working in labs are often overlooked, while the PI gets the fame and glory.
The "Primordial Soup" idea was co-opted by the popular press of the day (because it was a neat and easy to visualize concept) and was derived from a very weak experiential result that was quickly discarded. It's a shame that it has persisted in common discourse since it really has no basis in any current science.
Very good information thank you ❤
great set of ideas . average but uniquely curious academic . i feel you Lane.
Evolutionary Biologist here .
What does an Evolutionary Biologist do?
@@nahshon9998 They don't waste their time trying to teach anti-science religious nuts on the Internet science.
Vielen Dank für diesen Vortrag! Ich habe mich nicht getraut, dahin zu kommen, da mein Englisch für ein solches komplexes Gebiet ungenügend ist. Jetzt kann ich es in meinem Rhythmus anhören. 🙏🙏🙏
He had me at the non dna synthesis of molecules, but from there going to rna I don't think so. I think the first cells will have had to do without genetics, an alternative simpler method, to build more complex molecules and replicate, which was completely lost without trace once rna came onto the scene.
A cell can't do without its set of instructions.
@@rl7012 Rene is suggesting a simpler set of instructions that was replaced by rna. Not a difficult concept.
@@ThomasEWalker So dead dumb chemicals might not be able to knock out DNA or RNA set of instructions, but they might be able to accidentally create a simpler set of instructions?
When was the last time dead dumb chemicals did anything other than react?
Lane just spent an hour explaining a way that this can happen spontaneously without enzymes, which obviates the need for instructions on how to build enzymes.
@@brentfodera377 No he didn't. Not even close. Tel me then how did NL explain how abiogenesis happened? It would have had to happen without enzymes anyway the first time, that should be obvious. But please tell me where NL explained how life came about all by itself on prebiotic earth? How did millions of the exact right type shape, chirality of molecules all end up in the exact right place at the exact right time, with the exact right temperature and how did dead dumb chemicals that can only react, complete a work of chemical engineering that surpasses all man's achievements to date?
Best ever !!
I'm very curious to know what kind of experiments can be done to further explore consciousness outside of the orch OR model.
what are the origins of electricity?
The idea of a first cell forming is hard to imagine (no one has imagined how that could be yet ), but that cell would just die, so, we actually need a cell that can reproduce. If we can not imagine formation of a living cell, so much more so are we unable to imagine a cell forming with all the "machinery" intact that is needed to reproduce. We are so far, OMG, so far, from understanding the steps that led to the first reproducing cell, that later led to multicell live, and finally us.
Repeatable geological formations allows function to go before reproduction becomes possible. Function first looks right to me.
@@arubaga Nope.
@@gabri41200 How can you tell me to think outside the box when you are such a typical in the box thinker?
The universe is not infinite for a start. What evidence do you have to believe it is?
Have you studied abiogenesis? Doesn't sound like you have but I have and even for the simplest cell to form there are millions of sequence specific chemical processes happening. Science has no idea how prebiotic earth got the homochiral raw building blocks for life, no idea how all the building blocks came together at the same time, no idea how it was assembled and no idea where the information came from.
The universe could be a trillion times and bigger and a trillion times older and that still doesn't lessen the odds of life forming by chance.
Early cells could be multi-nucleus, so that cell division need not be precisely orchestrated. One single cell could host multiple nucleuses from allied species, like an apartment complex.
@@arubaga You are missing the point here, how did cells come to exist? They are highly complex, highly chemically engineered incredible machines. Even the most simple cell is still profoundly intelligently engineered and how was it built? Where did prebiotic earth get the exact right materials from? How did the exact right materials assemble itself with sequence specificity millions of times over? Even the cell wall is a double bi layer using thousands of different types of lipids with certain specific shaped openings, how did that happen on its own then?
You think a cell can be viable without information?? Why do you think that? You think multiple nucleus substitute for information? How is the multi nucleus cell made? You just ignore the biggest and most basic questions. Chemicals do not arrange themselves in non standard order. Chemicals react, they do not stop reacting unless the reaction is finished or someone or something stops the reaction yet you have assumed self assembling, intelligent chemicals here that have a plan to follow and are all working together to build life!! This is b.s. Chemicals can only react.
You lot skirt over the main questions without addressing the fundamentals.
An illuminating talk. I'm grateful to those who are committed to scientific materialism for doing OoL research. Results like those discussed in this talk powerfully demonstrate the shortcomings of the hypothesis of a materialistic/mechanistic origin of living cells.
Great job! He seems to have this knowledge very well assimilated by transmitting it so clearly, even to me without any degree in science. It would be great if I could ask him this: understanding or proving how “life” happens, would some kind of intelligence be out of the question, not a being, I mean, like a force that was the initial force of all these processes?
A very important detail is that when the cell has to decide, I am assuming that there is already a cell with the capacity to know that exist and is capable of feeling and making decisions.
Don't let bad language dominate your thinking completely. ;-)
Natural forces were responsible for these processes, but they needn't be intelligent. The forces that cause dense substances to sink and less dense ones to rise, thus causing them to spacially separate, aren't intelligent. That's due to easily understandable physics. The geochemistry and quantum physics that cause minerals to catalyze chemical reactions on their surfaces and make electrons tunnel between molecules are spontaneous.
We also know it's possible to make decisions without being intelligent. Computers do so all the time via if-then statements in software and logic gates in hardware. Behaviors that mimic emotional states, like aggression, fear, curiosity, etc., can be simulated with very simple electrical connections in machines (see Braitenberg Vehicles).
You might think these are overly simple examples of "making decisions" or "performing behaviors", but the first cells would have been much more simple than modern cells. And if you want to explain life, you ultimately have to do so in terms of things that aren't alive. If you want to explain consciousness, you have to explain it in terms of things that aren't conscious.
Nick Lane? Thumbs up before listening.
Here here!
I was looking for Nick Land :/
Thumbs up my butt
It looks like he's lecturing at a restaurant. It must have been a terrific meal. I wonder if the audience believes there was a chef or just electrical fields.
Seems like theres way more evidence that the ingredients the chef prepared came from electrical fields than a magical sky man poofing things into existence
Regarding electrical fields, the audience here might also be interested in talks between Nick Lane and Michael Levin. I believe at least one conversation is available on CZcams.
Dinner and a great lecture? Sign me up
Its only for bulimics
All Wars will continue until I am the president of Australia.
something missing. will war will stop if you are president? and is this about an election or blackmail? fascinating! tell us more! 🤍
Lol
We gotta elect this guy asap then
@JackAtkins-xz5wi
That's funny, because, as I've been saying for the last forty years, most humans' lives will continue to be fk'd up until I am King of the World...
But I support you as President of Australia.
(See that apostrophe after the word, "humans"? That's not an accident. Just another reason why I should be King of the World, among many.)
😂😂 that sounds more sincere, honest und serious than anything I heard lately from any politician in media - you have my vote!
Wow! The comments here are hilarious! Clearly not many biochemists commenting. As a biochemist I forget how little lay people know but how sure they are of their own whack ideas 😂😂
If oil had mostly biological origin and biological things often have nitrogen atoms in them in the amine functional groups of amino acids which are present in proteins, an important building material of life, shouldn't we get a fair amount of ammonia, etc. nitrogenous matter coming with the crude oil ?
N is about 1% in humans, as an example, so not really 'a fair amount'
Phil, You’re the reason lay people had to learn a long time ago not to trust scientists with truth. We are watching an old clergy die an embarrassing death and it’s being led by the arrogance that causes Harvard and Stanford to both be exposed for decades of data manipulation under your wing. You really shouldn’t be laughing right now as someone who claims to be in the current scientific community.
Today, we find oil six miles below the oldest fossil record. It’s very possible and even likely what we call oil is abiogenic.
Wow! The lack of self awareness here is hilarious! This muthafucka really started his sentence with an "As an [insert NPC adjective]..." unironically. You need to relax your use of mind-altering chemicals.
Right haha yeah, tell ‘em, right, yeah get ‘em haha😂😂😅😂
What kind of music was played before the presentation?
Two equal and opposite forces produce incredible complexity over time.
The electromagnetic dance of the electron and proton, the emergence of all we survey.
Complexity doesn't mean life. Zero evidence for any natural emergence either.
@@rl7012bro, "zero evidence"? The very fact that we exist is an evidence
@@gabri41200 Our existence is evidence of life, it is not evidence that life 'emerged' from accidental chemical processes. You think dead dumb chemicals accidentally invented reproductive life?
@@rl70121) Only natural forces exist.
2) Life exists
3) Therefore, life was formed by a natural process.
In order to deny this, you must deny proposition 1). In order to do that, you first have to prove that some supernatural force exists.
@@gabri41200
1) Is an assertion. What is your evidence that only natural forces exist?
Positive is dual to negative -- numbers or electric charge. Electric charge is dual.
Electro is dual to magnetic -- electro-magnetic fields.
North poles are dual to south poles -- magnetic fields.
Antipodal points identify for the rotation group SO(3).
Pure energy, photons or light is therefore dual, energy is duality, duality is energy.
Symmetry (waves, Bosons) is dual to anti-symmetry (particles, Fermions) -- the spin statistics theorem.
Bosons are dual to Fermions -- quantum or atomic duality.
Real is dual to imaginary -- complex numbers are dual.
Elliptic or spherical geometry is dual to hyperbolic geometry.
Positive curvature is dual to negative curvature -- Riemann geometry.
"Always two there are" -- Yoda.
Even (symmetry) is dual to odd (anti-symmetry).
The integers are self dual as they are their conjugates.
Sine is dual to cosine or dual sine, the word co means mutual and implies duality.
Vectors are dual to co vectors (forms).
Duality creates reality.
The Krebs energy cycle is dual:-
Yin is dual to yang.
Thesis (bacteria) is dual to anti-thesis (Archaea) creates the converging thesis or synthesis (Eukarya) -- The time independent Hegelian dialectic.
Clockwise (Krebs cycle) is dual to anti-clockwise (the reverse Krebs cycle).
Bi-stability implies duality.
Multi cellular life is synthesized from single cell life via the Hegelian dialectic -- the duality of the Krebs cycle.
Male (thesis) is dual to female (anti-thesis) synthesizes children or offspring.
The Hegelian dialectic explains why there are two dual sexes in nature.
DNA or the double helix should be called the dual helix -- the code of life is dual.
Hydrophilic is dual to hydrophobic -- hydrogen bonding or the DNA backbone.
A is dual to T.
C is dual to G -- Nucleotide bases.
Energy is duality, duality is energy == the Krebs energy cycle is dual.
Amidst all duality there is singularity which ancients have found in deep meditation which no one can find in subjective way.
Everything is hidden in something which cannot be divided further. I am wondering what is dual counterpart of Akasha ( infinite consciousness ) and Dark energy
@@kiranjoshi5267 Energy is dual to mass -- Einstein.
Dark energy is dual to dark matter -- energy is duality, duality is energy!
Potential energy is dual to kinetic energy -- gravitational energy is dual.
Positive curvature is dual to negative curvature -- Gauss, Riemann geometry.
Curvature or gravitation is dual.
The big is a Janus point/hole (two faces = duality) -- Julian Barbour, physicist.
Topological holes cannot be shrunk down to zero -- non null homotopic.
Points are dual to lines -- the principle of duality in geometry.
Covariant is dual to contravariant -- derivatives in General relativity.
Covariant derivatives are dual:- Changing the vector components whilst keeping the basis constant is the same, equivalent or dual to varying the basis and keeping the vector components constant.
Brahman (the creator God, thesis) is dual to Shiva (the destroyer God, anti-thesis) creates Vishnu (the preserver God, synthesis) -- Hinduism or the Hegelian dialectic.
Finite consciousness (man, mortals) is dual to infinite consciousness (God, immortal).
Form is dual to formlessness.
Absolute is dual to relative, objective is dual to subjective.
Apples fall to the ground because they are conserving duality or energy.
The gravitational force is empirical proof that duality is real.
Real is dual to imaginary -- complex numbers or photons, light are dual. Photons = pure energy or duality!
The big bang is an infinite negative curvature singularity, divergent (inflation) -- hyperbolic space.
White holes (divergent, entropic) are dual to black holes (convergent, syntropic).
Convex is dual to concave -- mirrors, lenses.
@@kiranjoshi5267 Dark energy is repulsive gravity or negative curvature -- hyperbolic.
Gaussian negative curvature is defined with a minimum of two dual points -- non null homotopic.
An infinite negative curvature singularity still requires to dual points hence:- singularities are dual.
Positive curvature likewise is defined with two dual points but the second point lies on top of the first point.
en.wikipedia.org/wiki/Gaussian_curvature
Spherical or elliptic geometry is dual to hyperbolic geometry.
You should read Julian Barbour's book about Janus points/holes.
Einstein ignored negative or hyperbolic space and threw theses equations into the proverbial waste paper basket, he also rejected black holes.
dual dual dual - what are you smoking?
@@BR-hi6yt I have done the hard work and then I discovered the 4th law of thermodynamics:-
Syntropy (prediction) is dual to increasing entropy -- the 4th law of thermodynamics!
Space is dual to time -- Einstein.
Time dilation is dual to length contraction -- Einstein, special relativity.
Space/time is 4 dimensional.
Energy is dual to mass -- Einstein.
The future is dual to the past -- time duality.
If time is dual then space is also dual.
Points are dual to lines -- the principle of duality in geometry.
Space, length or distance (lines) is defined by two dual points -- space duality.
Time duality is dual to space duality -- duality within duality!
Absolute time (Galileo) is dual to relative time (Einstein) -- time duality.
My absolute time is your relative time and your absolute time is my relative time -- time duality.
Absolute is dual to relative, objective is dual to subjective.
There is also a 5th law of thermodynamics or the conservation of duality (energy).
Energy is duality, duality is energy.
Gravitation is equivalent or dual (isomorphic) to acceleration -- Einstein's happiest thought, the principle of equivalence -- duality.
Was the earth a wet rocky planet with no life on it? The biggest issue I have with this statement is that while they can say to the best of their knowledge it was so, they cannot say it is true with absolute certainty. There is a tendency to let popularity of opinion in science to form paradigms that become unquestionable beliefs. The abiotic origins of life is, in my opinion, as absurd as the creationist origins of life. We have only ever observed life begetting life. Why did life start on this planet is not due to a series of lucky accidents from a random event in a chaotic pool of slime to the earth's orbit being in a goldilock's zone. The moon shares that orbit with earth, why doesn't it have life? The reason why there is life on this planet is simply because this planet is, in and of itself an organism, if not a super organism. Life is on this planet because this planet is alive.
"Life is an excellent guide to its own origins.." For only life begets life. A cell wall is analogous to a double layer in a plasma.
"its about biosynthesis, making the building blocks of life.." Only an organism has this ability, therefore, if life on this planet as we know it started in a pool of slime, that slime exists within the biosphere of the organism Earth. I like Nick, though I disagree with this basic premise, and I find it interesting that he says all these things that if he stopped and considered it with an open mind should lead to the conclusions that only a living planet can have life on it. But he doesn't.
He mentions the mid ocean ridges that reveal a stratified ocean floor that is much younger than the continents. It is generally recognized and agreed that along the mid ocean ridge are a series of volcanos running generally north-south spewing out lava which cools forming new surface area. The parallel stratification is also interestingly of different polarities thus suggesting to me that each new layer developed during or after a magnetic pole flip. Also, that this north south magnetic stratification suggests electrical current flow along the ridge. While the consensus belief is this new ocean floor subducts under the continents, but there really is no concrete evidence to support the claim. When tectonic drift or continental drift was first proposed it was resisted vehemently by the science community, but over the decades more evidence mounted particularly in the fossil record suggesting a single continent origins, though they believe on an earth of similar volume as it is today. The only problem is, the continents do not fit together nicely on such a sphere. Its either one side fits and the other is skewed and visa versa. But they do if you shrink the earth's volume till it is 55-60% of what it is today and you get an earth that is covered by a single continent with shallow seas, no Pacific or Atlantic oceans. It is argued in the Expansion Tectonic Hypothesis that the magnetized stratification through dating shows the material closer to the rift to be younger than that closest to the continents, that this stratification is in fact similar to a growth ring on a tree and is indicative of new girth and mass.
He mentions Mars and subduction and an untested hypothesis. As I said I do not accept the subduction mechanism. As for Mars, he offers an interesting story, and like he said there are many. What is also interesting to note about Mars is that unlike earth it lacks a significant magnetosphere that is several times its radii, Mars has small irregularly located magnetic presence on its surface.. The planet known as Scarface in all ancient languages, and it is fair to say the Valle Marinaris located at its equator does look like a scar as if it experienced a catastrophe. If Mars did have a significant magnetosphere of a similar complexity as earth or the gas giants, then it likely would also have had an equatorial electro jet like earth and that the Valle Marinaris located at the equator is an electrically induced scar. If this is true it such an electrical event would be globally catastrophic. And the Valle Marinaris does have the hallmarks of an electrical event. And such an event would also explain the missing surface mass. Well, that's my story. I hope you find it interesting.
Oh WOW! @18:31 "The topological structure of a cell and the topological structure of a planet are very similar to one another." Yes, Nick they are, especially planets like earth that is because they are both organisms of different scales. He sees it but he doesn't get it. This took me by surprise. Life is fractal from micro organism to multicellular organism, so why not up another magnitude to a planet as a superorganism. Thanks Nick.
Comparing the Kreb cycle to that which is going on in the hydrothermal vents is just more evidence for earth as a super organism.
"Life is powered by electric membranes." This is what made me curious enough to check this talk of Nick's out. It is interesting to note that Irving Langmuir who in the 30s was studying rarefied gasses would be the one who named them Plasma. Langmuir was also a biologist as well as a physicist and what he saw in these gasses were what he considered self organizing properties like that which he had seen in blood plasma. A plasma double layer is literally an electric membrane.
Hydrophilic and hydrophobic codons are analogous to Q- and Q+ polarity.
Consciousness, at its foundation is an awareness of self and one's environment. Electromagnetic feedback takes place on many levels within an organism. Our senses are a product of electromagnetic feedback. Like all life on planet earth which has a magnetic presence that extends beyond its physical self, so too does this earth. We as organisms of earth are electromagnetically connected to earth. There is a French researcher who builds Faraday Cages and built one to block the earth's magnetic presence and then tried to develop frog embryos within the cage. They all mutated. Dr Rupert Sheldrake of Cambridge proposes the hypothesis of morphogenesis, that the code for the patterns we see in chemistry and life are the product of a morphogenetic field. I believe this field to be intrinsic to earth's magnetosphere.
This was a great talk and has provided me with some interesting data for my far out hypothesis of earth as a superorganism. He does give a good talk and I love his enthusiasm. My final point. A lot of his talk was about charge potential between acidic and alkaline environments. What is charge? We have a mathematical description with some analogies, but in the end, charge is a mystery. What is energy? It is an abstract accounting tool for the ability to do work. Its a concept more than anything else. What is life? Here again, every time we have tried to define it, something new comes along that breaks that definition. In the search for alien life, it is suggested we have no definition, otherwise we might miss it especially if it were right in front of us on a celestial scale.
Just to be clear, my interpretations of some of which Nick presented are mine and I am not suggesting in any way that he would approve, or not, or that he is suggesting in any way that which I am suggesting. I merely offer an alternative interpretation to support the hypothesis of earth as a superorganism. .
You could have just stopped after your first paragraph. Anyone who read it knows there's no point reading anyting else you wrote.
Life is for living.🎉
lol typical moronic troll comment@@TonyTigerTonyTiger
God did it. No reason to sweat it
@@keylanoslokj1806 You said an invisible, immortal, eternal sky wizard went POOF!, without providing any evidence whatsoever. Your argument is so convincing. 🤣😂
Very very fascinating!
fairy tales often are
@@rl7012you've made 81 comments on this channel. Is that a personal record?
@@barcadna You counted them? 🤣🤣🤣🤣 Thanks for the laugh. How sad are you?
When you say Krebs cycle pulling out CO2 and Hydrogen, what you're really saying is breaking down fats and carbohydrates. Our genetic make-up evolved around the availability of such substances for fuel and renewal because it's a lot easier to do than break down rocks, so we had more time to do other things like grow fins and make Powerpoints. (Nice job, btw) Everything after that is gravy.
Thank you for signing my copy of Transformer!
It is not just a wet world that harbors life, it in fact is a longer story in which various conditions that doesn't harbor life permits a time period that permits life to flourish and sustain along with the evolution of consciousness, intelligence, intuition etc., if not to permit further evolution (without understanding what they entail). Electrical origins of life is indeed interesting, but doesn't count out other reasons.
Did you actually watch the presentation? Not sure what your "point" was, but it certainly wasn't science-based.
I don’t think humans will ever be able to create life. I’m glad he stated what he did at the beginning. Fascinating talk
We are already creating self-replicating life in computer simulations. Research digital life....
You are correct... you aren't thinking. What you are doing is called "emoting" (and it's not a good thing, either). ;-)
Possibly relevant is that there are only 22 coded (proteinogenic) amino acid whereas there are potentially thousands of non-proteinogenic amino acids, some which have been found in meteorites. The extent of NPAAs' effects on nucleotide bases is an intriguing question.
From the first instance of a tiny little speck of something that got blasted in some way and started blooming over and over and over again and still has yet to stop in any way. And why the harder we look into those tiny specks we see them doing more and more strange things.
The great Nick Lane. His recent fascinating book "Transformers" is worth a read or listen.
What a wonderfull story.
He is good at telling stories. Kerching
@@rl7012 .... life means ... telling stories ... everytime ... everyweher ... i like both ... evolutionist and creationist ... one day , both will meet at OK coral ...
Thanks , obrigado !!!
You should talk with the electric universe guys. I bet they'd love that
I am impressed with how much science understanding has come along with studies of life origin.
Not a well funded field of science either, is it?
Though it still barely the abc's yet.
With interesting speculation now of could there be life on the moon Europa i guess the interest is gaining afoot?
My other guess is those hoping abiogenisis will forever be a mystery will
someday in the distant future be sorely disappointed.
Excellent
'we don't need to specify how that works'. Yes you do Nick. That is exactly what you need to do mr hand waver.
Excellent presentation! It further reinforced my belief in intelligent design.
Fascinating to hear a cutting edge, and brilliant scientist both assert that the self and other are necessarily unified, and that consciousness is a product of an electromagnetic phenomenon.
Mitchell was awarded the Nobel Prize by himself, lol 28:00. Just kidding on the double meaning, many thanks Nick.
53:07 They arrange into octagonic & 12-gonic & 24-gonic structures.
Spot on on most of his talk in biodynamics this is our understanding Steiner talks about the doubles. The only slip up was the adding of the world of viruses which has yet to be proven re purified and isolated. Thank you for your curiosity
Agora a biologia tem um novo paradigma como a física
Thanks.
A luta o que vence é o mais adaptado é contra as civilizações que o programa SETI procura e será travada através da viagem no tempo
outstanding
set your bar higher
Most important work in biology/chemistry
Very interesting research. I believe that many more phd-students are needed to fully understand the topic….If I started as a phd student again I would study the biochemical interaction processes between bacteria in the body and the brain. Since we have 10x more bacteria in our body then cells, the syncronization of bakterial behaviour and interaction with the human body might be an important process, is my gut-feeling….
".If I started as a phd student again"
Again? As if you ever were one.
Very enjoyable. Electrobiochemistry? You neglected the potential assistance of microscopic piezoelectric assistance.
What I find incredible is the fact that 23 codons have a linguistic "synonym" structure and function and the other 23 are "homonymic."
What I find incredible is that you think you made sense. There are actually 64 codons but some are redundant. Codons are three nucleotides in RNA that code for a particular amino acid - 20 standard amino acids. How each of those are arranged then specifies a protein.
You appear to have failed to understand what a synonym and homonym mean in the context of codons.
@@anthonylawrence5842 You just fail!
@@anthonylawrence5842 Well, explain to us how 23 of the codons are supposedly homonymic. Because based on the actual meaning of the word "homonymic", the term doesn't apply to codons.
@@TonyTigerTonyTiger 23 are synonyms which refers to "words - codons" which are different but can have similar meaning, these are not context dependent for their meaning. 23 are homonyms which are "words-codons" which are the same but have different meanings. The only way these can be understood is by reference to the context - the wider DNA environment including probably the so called "junk" or non-coding DNA. DNA can therefore be said to exhibit a quasi-intelligent linguistic structure.
Very interesting talk that triggers gazillions of other questions. Seems like gradients of any physical property plays a big role, including photonics, which I don't think was mentioned in this talk. Also, after baseline laws are fully formulated, testing and further evaluation probably will be done in Quantum Computers with Reinforcement Learning Algorithms. That's the only way we can emulate billions of years of evolution. After this talk, I am very hopeful that we'll have a respectable theory within 10 years or so. We need this info to populate other planets.
The last part of the talk is a bit of convergence where Lane seems to give nods to Karl Friston, Michael Levin and even Mark Solms (for the feeling bit). What a great age of discovery we're in.
(15:47) It's no good using a laser pointer to point to a complicated chart for people watching on youtube. I expect some of the people in the room would have had some difficulty following too. What you need to do is edit the slides into the video before uploading.
Just because the electric flow in a system can be described does not mean that it is organized by electric current; Just as in an electronic system of a telephone, the electrical flow builds the telephone.
Fascinating, intriguing very clever and brave but there are still so many unanswered questions. For example now that this cell has formed and sustains “life” how did it figure out to duplicate itself and why did it think that’s a good idea and necessary?
Who said this first cell would think?
@@TonyTigerTonyTiger poor choice of word on my part I guess.
The origin of life isn’t one point and in fact several points and not like different matter but different versions of life emerge from areas and interact with the environment and as that change and the environment changes the life dies but leaves behind a difference in one area or many areas, like a rock hitting multiple plants as the rock rolls down the hill and creates changes that bring forth new differences that can emerge. The hill is like earth and the plants are differences and as it moves along the reaction of reality it can cause changes. Cascading differences that can connect and separate. Similar to how matter flows and connects in water or some other medium. All it takes is energy to connect and the energy gets translated/transmuted by things. Energy leads to difference and difference leads to life. We just need a lot of difference and the emergence doesn’t happen because it’s all stable but because portions are stable and those portions interact like a scale that translates the differences and uses them to not break down. Like growth through separation can be growth accumulating. Oh and that’s why life is also thought to not originate on earth, parts could have not originated here and got into diced later like water smashing onto the planet after floating in space and now 2 differences can create a bunch of smaller differences and similarities to construct new. Like when the number 1 and 2 collide and the parts sometimes match or sync in ways similar to the rotation and the waves and and the waves create changes in the pathways for mixes. Like storing the cool side in a different direction. Like left and right handed molecules or like positive and negative electrons and then the variable intensities. 1 and 2 can break down into infinite parts to create anything between and then that can work up to 3. Humans can become gods or what we imagine as gods but through the infinite possibilities or potentials. It’s not what created us but what we do with the creation. We aren’t the body or the flesh but a combination of the parts working together with the universe. If you read this far, crispr and gene editing may be a difference that can connect to humans and grow us in a difference that could give us more genes to do more things or clean up the pool and make us safe to the outside. It just needs to be explored like how the universe explores through us. Maybe we are the pieces in sync. When our pieces desync by lack of energy, patterns, cellular structures, we fall apart, but there are pieces we leave behind.
Nick was talking about consciousness... well, good he knew about the hard problem, but it went flat promptly. For years we were told , depression, shizophrenia etc. were the unbalanced dopamines or serotonins in our brains. It not exactly the case. as we know now. The build up of dopamine can be from eating a donut or getting the kiss - or from thinking about going to space, and the mix up is messy - do you think we can compute that!? if so give me a call
Hi. The computation is presently beyond us. In the same way that a Picasso is made only of defined chemicals, it is something about the distribution from which a pleasing order emerges. I hope you don't mind the analogy.