Phosphodiesterase inhibitors

Phosphodiesterase (PDE) inhibitors play a wider clinical role as the drugs can act on different types of enzymes located at various organs. In this video, we will discuss important drug targets acting on PDE.
#pde5inhibitors
#phosphodiesterase5inhibitors
#sildenafil
0:00 Introduction
0:09 Phosphodiesterase inhibitors
2:06 PDE 3 inhibitor 20-30 times more ionotropic
5:25 Thrombin ADP, TX AZ
6:42 CILOSTAZOL
6:52 PDE 4 inhibitor -AST
9:14 PDE 5 inhibitors Erectile dysfunction
9:20 Corpus cavernosum
10:53 Non-selective PDE inhibitors

[@sabikunsatil1393]

Wow.. so well explained... Thank you.

[@B3bita1215]

Soooooo I finally understand why phosphodiesterase inhibitors cause increase calcium ( IN CARDIOMYOCYTES) and decrease calcium ( IN CORPUS CAVERNOSUM) 😭 Thank you very much kind sir. You did an amazing job explaining this concept. ❤️

[@MuralisankarBpharm]

Yes I too...🙏

[@abukeabdela4928]

Really helpful... U cleared all my confusions

[@egpat]

Glad it helped. Thank you and keep watching.

[@ethar3059]

Tadalafil is the only PDE-5 approved for BPH

[@abdulshakoor4198]

Very well explanation

[@rajendran2502]

Thank you sir.😗

[@MuralisankarBpharm]

Sir onething..
U said dypiradamole inhibiting adenosine reuptake...
Then it will potentiate the adenosine action..
But u said block the adenosine action...
Which is correct sir..?

[@leelakrishnan5954]

Awesome sir

[@aventadorgamer1575]

Very useful

[@ShivaKumar-bb1zl]

Always thankful to you sir.....
Can you please make more lectures regarded CNS DRUGS...

[@egpat]

Sure. Meanwhile you can watch few videos in the playlist if you haven't watched already. Thanks for your interest.
czcams.com/play/PL4xEvkG4GFD_fiJcfU8cggRYdb2x54m_L.html

[@ahmedahm1]

7:17 MILAST (RofluMilast, ApreMilast and CiloMilast)

[@Suresh-ls9rk]

Thanks sir

[@inspiredsoul.]

It's so much helpful

[@egpat]

Glad it was helpful! Thanks for watching

[@navdeepfhijain1913]

Adenosine inhibits platelets aggregation not increase aggregation

[@ranjanmallik5291]

👌👌👌🙏🏻🙏🏻🙏🏻🙏🏻❤️❤️❤️💚💚💚🙏🏻🙏🏻

[@immadisarojini2775]

Super