AET London 2024: Bispecific Antibody Therapeutics: Challenges, Opportunities and Future Directions

This talk, “Bispecific Antibody Therapeutics: Challenges, Opportunities and Future Directions” was given during the 2024 Antibodies Engineering & Therapeutics Europe meeting in London, UK, by Robert Ford, PhD, Field Application Specialist at GenScript.
In this presentation, you will learn about bi-specific antibodies (bsAbs) demonstrating novel functionalities that yield remarkable promise in improving the drug therapeutic efficacy through the recognition and targeting of two different antigens or epitopes. Although the optimized purification of mAbs serves as a good starting point for the purification of bsAbs, further optimization is challenging due to the differences in their intrinsic structure. In this talk, we provide insights into the various architectures of BsAbs, focusing on strategies for production.