Dr David Sinclair Describes His Entire Longevity Routine
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- čas přidán 27. 12. 2019
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David Sinclair describes his longevity routine. From Modern Wisdom Podcast episode #066 PROFESSOR DAVID SINCLAIR | Can Humans Live For 1000 Years?
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#davidsinclair #longevity #nad
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Chris my mom is 63 . She had an MRI ,and has these teeny white patches in several areas of the brain. He said it’s not MS . He says it could be regular aging and there’s some brain shrinkage. The white patches are in the teeny blood vessels in the brain. She doesn’t smoke or drink ,but has trigeminal neuralgia, and CRPS,so she takes morphine when her pain gets bad . She is 30 pounds overweight.
She’s in Canada and so I’m wondering is age 63 ok to start taking Metformin,NAS ,and reservatrol, could David’s regimen actually reduce her symptoms and possibly help the brain/ white patches that are showing up in her blood vessels on the MRI? 🙏in advance.
Summary:
NAD booster 1 gram, every morning (water soluble)
(along with) Metformin
Resveratrol 1 gram, with few spoons of yoghurt ("Bravo" with special bacteria)
Baby aspirin 81mg (for blood thinning)
Excersising
Fasting
Tnx
How much metformin
@@relaxwithme9453 Half to a gram, he says that in the very first minute of the video.
Where do you get the legit ingredients from? The NAD, Metformin resveratrol?
What is this reversatrol powder he is talking about
Thank Gawd for the comment section hear, I almost listened to the 50 year old scientist who looks 35 and has been studying this for 30 years in the leading edge of science. Thank
😂
When in doubt it's always best to trust a bunch of ignorant CZcams commenters.
Well he does have investments in all this so bias is always present.
@@illuminated2438 or very experienced and passionate researchers on CZcams etc
I almost bought his book
The men in my family, father, uncles, older cousins, etc mostly died in their 50’s and early 60’s. I hope to buck the trend and live to a remarkable age, say like 80
Live well and take care. Government or private enterprise will not fix your health for you.
Eat a low carb/sugar diet and do intermittent fasting...and you'll likely be well on your way. Good luck!
My great grandpa passed at 106, and my grandpa is 80 with no physical ailments so hopefully our trend can continue
Wow 80 is normal for my family. My grandma is 86 and she travels NYC all by herself to go shopping. Her walking speed is amazing for her age.
80 is not a remarkable age, is the average life expectancy. Aim higher.
Avoid processed foods, avoid processed sugars, avoid table salt, avoid, avoid undue stress, avoid drugs, and avoid negative people,
so I should move away from america is what you're saying? lol
@@OwOLink Yeeeesssss.
no no the drugs,,,!
I think you should fast two times a week, exercise,drink a lot of water, eat fruits and vegetables, low protein, a multi vitamin at least once a day,sleep at least 8 hours,meditate, and be kind.
I like your thoughts better...
Sounds good to me
Water is overrated
For very different reasons, NAD+ has also attracted a wave of attention from cancer researchers. Recent studies suggest that cancer cells of many types depend on NAD+ to sustain their rapid growth and that cutting off the NAD+ supply could be an effective strategy for killing certain cancers. The data from these studies paint a more complicated picture of NAD+ and raise new questions about the diverse ways taking an NAD+-boosting supplement might influence health. “It might still slow down the aging part, but it might fuel the cancer part,” says Versha Banerji, a clinician-scientist at the University of Manitoba. “We just need to figure out more about the biology of both of those processes, to figure out how we can make people age well and also not get cancer.” This is just a fellow up to my previous post. Interesting that most sites are ignoring the possibilities of its effects on cancer.
nice info..thanks
@@jitendrasemil342 google: popular anti-aging supplements - scientific american. it talks about cancer and NAD+
Yeah high protein when exercising prevents muscle loss and builds muscle, but also feeds cancer as cancer is reliant on protein to proliferate. If you have cancer avoid nad sups and protein. If not, go for it.
Graviola/guanabana and Apricot have anti cancer properties
@@G.Bfit.93 some cancers are actually reliant on carbohydrates and because they cannot process ketones, a ketogrnitc will cause cell death in cancer
Excellent presentation
Two of life's role models. Dr. Sinclair for physical health, and Dr. Jordan Peterson for superb mental health.
lol
Didn't Peterson literally go crazy?
Your role model for superb mental health is a conman drug addict who makes money coaching 16 yo extremists?You should rethink your life decision that made you reach this point lol
@@gs-nq6mw Oh wow, you sound like a special kind of person
@@teddybearroosevelt1847 special kinds are the depressed people financing ar charlatam😂
Thanks for sharing your knowledge. One pear a day help to reduce bad colesterol.
this was my question about breaking fast with this 2 spons of yogurt. thank you! i can sleep peacfully now)))
yes it does break a fast. read my comment above
@@vanillaglue ok, about breaking fast I agree, but why do you think he doesn’t look younger then his age? I think he looks really good
I know, I was finally having this issue last night but I just decided on a teaspoon of olive oil with Resveratrol & it was just fine.
But I'll probably start yoghurting it if I start making my own
Thank you for this video. Can I please ask what form of metformin Dr Sinclair takes: the slow release or instant release? Thanks.
could I substitute another stilbene compound like pterostilbene for resveratrol?
Turmeric and pepper extract help with blood flow,no aspirin required
Or Grapeseed extract. Here in Germany Grapessed extract is big. You have to stop taking it before surgery because it makes the blood too "liquid", so it has the same properties like aspirin only better and natural
Ginko biloba does a far better job, with a tonne of added benefits,
And should be taken together piperinr in pepper increases bioavailability of turmeric up to 2000 percent!
No need to take statins either - so many ways to lower cholesterol, that’s gotta be the worst one. Also don’t know what type of cholesterol is high for him, if it’s not VLDL or sdLDL then he’s got nothing to worry about there.
D aspartic acid make my veins huge.
L citrulline is known to help blood flow it's in watermelon.
Anyone have a precisely written down daily routine including fasting and exercise?
The properties that make the Bravo yogurt mentioned by Dr. Sinclair unique are described in detail in this article www.biorxiv.org/content/10.1101/714154v3 where its GcMAF and anti nagalase activities were evaluated by an independent laboratory. This article already is in the top 25% of all research outputs scored by Altmetric (attention score), see biorxiv.altmetric.com/details/63993873
Great routine! Thank you.
I think this video is very good. Thank you.
Thank you Mason, hit subscribe for more!
@@ChrisWillx Your most welcome I really wish to understand more.
I keep seeing comments like this, its confusing me, please help"
Every time I have tried NAD+ I have felt terrible. Niacin interferes with b vitamin methylation and I have a genetic variant that already reduces my methylation considerably. I do take methylated B-12 and folate, and I find that I need B1 and B2 daily to feel my best. I also avoid B complex vitamins like the plague. They really pile on the niacin in those things which for me makes them worse than useless."
I also heard someone say NAD made their allergies return.
Read my comment above.
for methylation support Betaine (also known as Trimethylglycine or TMG) helps. Synergistic with NMN/NR
Thank u For such great info.
I’m taking aspirin as well …
Where do u buy NAD BOOSTER??? ❤️❤️❤️🥰😻
Best Resveratrol please ?
what brand of resveratrol do you use. i see Trans-Resveratrol, combinations of blueberry, acai , and other with japanese knotweed. and what strength.
I also have to decide between normal resveratrol and trans resveratrol, there are pros and cons for both of it, I guess everyone has to test it for himself which is better.
@@Viv8ldi use trans resveratrol 1gm
He uses trans resveratrol- he said it’s more effective in clinical studies
@@LaurenLarsontake a look at Nutri Vita Shop on the net . Pharmaceutical grade of trans resveratrol. And NMN
Its not harmless
Why were the resveritrol clinical trials stopped if it works so great?
Sr Sinclair in his 50's without a grey hair. Me at 33 with a random patch of white hair (white no grey) in my beard..... none on my head yet though..... My grandmother lived to 98 and she never went grey, she just went from brown hair to snow white hair. She developed Alzheimer's at the age of 89 however. Hoping to prevent the mental decline myself. With any luck in the future no one will have to suffer through dementia again.
thanks for the upload. good discussion on what technical breaking of a fast is. probably different for different people. For me, sometimes even if I eat a dash of sugar in some coffee in the morning, my entire metabolism will change and ill instantly feel sluggish, same for if I eat a yogurt. but it depends on the day, so many other factors I try and fail to keep track of though, complex machine this body.
I find that my body responds in a very similar way to different inputs. Gotta be so particular sometimes!
the main difference would be in the gut microbiome each one of us has, that would be my informed guess
That’s because your body has two states fat storing and fat metabolism. When you take only a gram of sugar your body says owe time to store that gram of sugar. You then feel sluggish. And you delay your body to turn to keto sis and start using your fat for fuel.
Hey guys great video! I do love short videos that get to the point and put out the information without all of the filler! Thank you! I do have a question: NAD booster seems to be a more or less generic term. Can you tell to us, your audience, the name of the specific NAD booster that you use, Mr. Sinclair? Many thanks guys!
Paul Dixon He takes NMN, can also take NR instead, look them up
I take an NAD that is the best on the market....it's not synthetic and is clinically proven to work better!! heart.lifevantage.com/us-en/shop/protandim-nad
Tara Wilson any feedback how it works for you? How long been taking it? Cost?
@@willcook403 She is selling it...
Where do I order Metformin, NMN, and Resveratrol? And how do I know if it's genuine?
Please, what excactly is an NAD supplement? what does contain it? I dont know all the stuff he is talking about except the resveratrol
Nicotinamide adenine dinucleotide. It’s a coenzyme that your body produces which helps your metabolism operate. The levels go down with age. You can take B3 vitamins for example as they produce NAD. But it’s only really going to make a bigger difference if you are old and cannot produce enough NAD yourself.
@@kakam458 u are awsome thanks a lot
I make my own yogurt using Lactobacillus reuteri from BioGaia (Sweden), take a NAD booster and resveratrol but Metaformin caused a tasty metallic taste after several weeks that made food taste revolting. I simply abandoned it. But the above combined is a very potent age reversal combination in the areas of physical vitality, physical appearance and mental clarity, I have observed personally. Starting TRT only because my 'free' testosterone remains stubbornly very low although my total testosterone is well over 700 ng/dl at 62 yo. I have been lifting weights since the age of 25, but as men age sex binding hormone globuline (SHBG) increases steadily which strongly bings to testosterone reducing the 'free' testosterone percentage.
Lift weights for testosterone boost.
P soreson if you havnt already , check out tony the herbalist on utube, I have made his red grapefruit , red onion and ginger formula, and then his red wine , garlic and abscorbic acid formula used for a week with impressive results . Effects exactly as described by him. In actual fact , I ended up making both then put them together in one jar, and then made a seperate batch of wine garlic and abscorbic acid my circulation has improved dramatically , more energy and skin super health by the way Sinclair mentioned in very recent video that latest research on oleic acid I found in olive oil avacodo is 10 times stronger than reversatol , so go figure,,,anyway best of health to you mr P 😀
I bought Dr. Sinclair's book "Why We Age and Why We Don't Have To." It's so educative and phenomenal. Through him, I learned about NMN supplement particularly by Vitruvin Health 500mg, it's been a couple of months now as also recommended by a close friend. All I can say is that it’s cost-effective, overwhelming energy is felt, and promotes your overall health...I am looking forward to feel and see the same result in the following years…
Supplements are so unregulated that it would be very useful to know where he purchases things like resveratrol, since I assume he tests everything he takes.
Yeah, the supplement industry is basically full of snake oil salesmen, just look at the shit Gwyneth Paltrow is allowed to sell.
-Check the stuff on Amazon over on the "fakespot" website. Half the reviews for NAD+ and NMN have a F grade for reviews, meaning there's a high chance they're all bullshit. I'm not spending $50 a month for something that could basically be sugar pills.
Bryan M Fair call ... hey, what’s wrong with a $70 candle that smells like vagina? I can’t think of a better way to spend the money... Now, where’s my credit card?
Id say most supplements are from young guys in their garages running one man assembly lines of Chinese bulk mystery powders.
he says he has his own stash from former work
👍 where would you find a NAD booster? Are there any foods that would suffice?
NMN - amazon
Which brand does he takes?
For the last few months, I've been taking one tablet each day of NMN-Vitruvin Health supplement. I'm astounded to discover that my metabolism now functions as well as it did when I was a younger. Other outcomes aren't nearly as visible yet, but I saw a significant boost in energy and concentration. I'm going to order another few rounds from their website. It took around just 3-4 days to see a difference.
Any food is breaking a fast but it’s still intermittent
Even if he is very super smart and i like him it sounds crazy to me to take all this stuff. Playing with fire
Attention David Sinclair: @
nice video! does he die his hair?
Does anyone know of any reliable online stores selling the suggested supplements?
Its a nightmare. There are so many companies and websites. "Credibility" is incredibly hard to determine. I got mine from Alive by science but its just a gamble and have no idea if its the real deal. I bought NMN and its supposed to taste somewhat citris-y and the stuff I got does so maybe its real but I dont know.
I'm in love with David!
- Javier Oliveras
Me too!
Me too
We love you too Javier
He didn't mention nmn or was that the Nad booster?
Hello doctor, is there a treatment for a person with a stroke in the brain in the behavior area? Do you have any treatment?
What’s the behavior area of the brain? Do you mean the whole brain by any chance? Oh maybe you could leave out the occipital lobe.
Interesting how aspirin comes from red will bark and the traditional tea my parents told me to make during covid has red willow bark as well.
The Bravo kits to make yogurt are very expensive
madmiky696 ive seen a couple of websites that sell it, its like they are copying the name, im not sure which one is the original..
and useless. you can make yogurt with just a spoon full of any yogurt + milk. The other bacteria in his yogurt don't survive because they're overwhelmed by the two main bacteria in all yogurt: Lactobacillus bulgaricus and Streptococcus thermophilus.
It's not enough to break ketosis. It's enough to break a fast.
exactly
I was on a strict keto intermittent fasting regimen after I was diagnosed with diabetes. Once I got my a1c down to 5.2, however, I started adding more carbs and fasting less. My a1c has remained normal. My point here is that my diet was terrible before my diagnosis. Now it's what it should have been all along, and it's not that strict. It just isn't awful. As long as one has lots of ketones, I think one should be fine. I measure mine periodically with a urine test strip, and my ketones have remained high. That means I'm getting fat out of my cells. In other words, I agree with you. ;)
What’s the nad booster?
where is the best place to buy NMN and a NAD supplements
lifeextension.com
Street corner or back alley
So what is metformin anyway? He said it originally was a natural molecule, then tweeked. Kind of how St. John's wort was tweeked into Prozac? What is it?
Berberine is the natural equivalent.
What's his nad booster?
NMN that he has left over from his studies.
Longevity is definitely people's choice. If you want to live long, work for it.. For me, I after watching Dr. Sinclair's NMN reviews/discussions, I felt relieve that it's now possible to slow the progress of aging.. lol I've been a devoted Vitruvin NMN taker and 'til now, I don't have medical problems.. I am enjoying the benefits it gives me every single day..
Paid ad by a troll
@@alfredhitchcock45 Hope it'll work for you as well :)
Oh! So you're a Vitruvin taker too? My sister used to have grey hair but through this supplement, it shoed so much improvement. The grey parts did not reverse to black but it turned a bit darker than before. Also, she is now spending more time in her yard more than the usual. She's 66, fit and healthy!
Doesnt berberine has a similar effect to metformin?
Has David switched from NMN to NAD+?
No. He said he takes "an NAD booster" which is just a roundabout and secretive way of saying he takes NMN....which many people know is an NAD+ booster
I really like Dr Sinclair but we still need some human studies with NMN. The stuff is not cheap and we still don’t have proof it works for humans.
Elsewhere he's talked about having tested himself and how this amount serves to boost his NAD levels.
As for longevity effects. We'll be waiting a long time for those trials to come in...
I've been using it in powdered form. It costs less that way. It really helps with energy. When I don't take it, I really notice it.
Micheal Bee Hi! Do you mind sharing of where do you get it from? I really want to switch to NMN (from NR) but it is so expensive 😩 Thank you in advance!
More recent studies have demonstrated that orally ingested nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) get almost entirely converted to nicotinamide (NAM) in the liver: “Intravenous administration of nicotinamide riboside or mononucleotide delivered intact molecules to multiple tissues, but the same agents given orally were metabolized to nicotinamide in the liver” (Liu, 2018). “Thus, the majority of the orally administered NR that reaches the muscle appears to enter in the form of liberated NAM. […] NR exerts only a subtle influence on the steady-state concentration of NAD in muscles” (Frederick, 2016).
Well I mean if we do nothing, we know exactly what will happen. We will get worse and worse over time and die like everybody else. At least with this we can say we TRIED. Life has a 100% fatality rate and no one makes it out alive.
How would you get a doctor to Rx Metaformin -- if you aren't a "diabetic " risk ?
In another video I recall he took the Merformin at night and in the off-days training ... maybe morning / evening makes no difference, just saying
Ya i remb him saying that
I remember him saying that he takes in the morning only. Now he says he takes 500 morning and 500 evening. Maybe he increased the dosage for twice a day.
He only trains on weekends so he doesn't take it on those days
yep, he's diabetic. and the medication counteracts the benefits of exercise. and there isn't research that indicates that taking a day off when you exercise is enough for it to NOT counteract the benefit of exercise. I.e. he might be spinning his tires.
@@vanillaglue DS is not diabetic. Ref research and exercise DS said there is some evidence it might be better/least worst than taking it daily. Rhonda Patrick made similar references too ... let me know if you find otherwise, cheers !
I use Berberine instead of Metformin. Nicotinomide Riboside and resveratrol. Also broccoli sprouts. I use intermittent fasting as well. NAD should be taken with a methyl-donor such as N-acetyl cysteine because it will deplete you, especially if you are taking niacin.
He said metformin will reduce your gains from exercise. What is berberine ?
Thank you for the suggestion. I do not want to take metformin, looked up berberine and it seams to do the same job. Never heard if it before.
Berberine is not as safe as metformin, though. Some foods such as yogurt, miso, kimchi, and many others contain probiotic bacteria. Berberine might kill certain probiotic bacteria. If taken together, berberine might reduce how well probiotic-containing foods work.
As far as autophagy goes I’m pretty sure that would break a fast. I’m not an expert, just listen to a lot of the information out there. The statin I would be worried about. There’s all kinds of horror stories out there about stations causing things like dementia. Scary stuff. I certainly wouldn’t follow that plan for myself. I am interested in the metformin. Currently do resveratrol and NR. Thinking to try nmn.
There are also quite a lot of strokes happening after quitting the statin in guys having cholesterol level in their 500s or dven thousands. They have their use for sure.
This guy is a genius. Read his book LIFESPAN. He teaches at Harvard Medical School.
Why not demonstrate discipline and wait until noon to break your fast? That doesn't make any sense to break it with a couple spoonfuls. I understand that the heart disease and cholesterol link is controversial. At 55 my doctor recommended statins and when I resisted he suggested a calcium scan. It came back zero and he said I was good to go. I have thereby avoided a drug with side effects for 13 years.
Nice
what is calcium scan and what came back zero? what is your cholesterol after scan?
Because he has work to do in the afternoon. A couple spoon full of yoghurt won’t add much to your calorie intake.
He needs to since he's taking metformin
Couple updates.. I believe David switched to taking metformin at night. If he is going to exercise, he just doesn't take it. Also in regards to the Nad booster, (which we have no idea what he recommends, other than if you take the right one it would cost you thousands of dollars per year) didn't he up his dosage?
How can you get metformin without a prescription in the uk?
Ditto
Ask for a prescription. Most MDs are aware of the benefits of metformin.
How can you get Metformin if it requires a prescription in your country?
It's OTC everywhere
Ask your doctor for it. I got it this way.
I've been taking Reservatrol and NAD now for 6 months, which brands are highly recommended?
I prefer lifeextension.com.
@@arnieperez49 I see that corporations have started cashing-in on these stuff
@@sepg5084 Maybe but lifeextension has been around for along time. I've been buying my supplements from them for about ten yrs now.
I'm following his diet, well not exactly like him....but yes resveratrol for both self and mom(she is nearing 70), probiotics. Feel good.
Heard of yoga and ayurveda?
Lactose intolerant here so I just take prebiotic for my bowel and probiotic for my gut. I also take L glutamine to repair my intestines from years of alcohol. Beetroot is good for high cholesterol as is garlic etc
I was on Statin and it was causing muscular damage my doctor said and he switch me on Crestor and I had a few bad side effects like chest pain and I quit them and I take only one aspirin a day and I am strict on my diet, lost 37 lb, I avoid process food and hardly no sugar now, I take Moringa leaf powder for arthritis and turmeric every day and I am. in lot better shape. in the long run sugar was my worst enemy. I eat wild meat that I hunt and fish that I catch myself only
I had severe problems with my hands, my finger joints would get really big, I could not close my hands and make a proper fist, opening and closing my hands often my joints would make a noice like squeaking and extremely painful and would keep me up at night. I take 3 capsule size 00 of organic Moringa leaf powder a day before each meal. It took a just a few weeks for the pain to go and I should say after 9 months it as improved by 90%
Do not hesitate to ask any questions
Thanks for the reply
OMG organic meets good
Organic Moringa leaf powder
@Zeek Banistor I use vegetarian capsule size 00 that the equivalent of 75% of I/4 tea spoon
@Zeek Banistor Each vegetarian capsule size 00 contains about 75% of I/4 of a tea spoon
PJ is that 9 capsules a day or did you mean 1 each meal - it’s for my mum she’s 73 and has bent fingers..
Organic Ceylon Cinnamon is a great natural blood thinner...
Make sure it’s an water extract cause fat soluble can damage liver
Did anyone tried his yogurt recipe ?
its just a regular starter culture. you can make yogurt with just a spoon full of any yogurt + milk. The other bacteria in his yogurt don't survive because they're overwhelmed by the two main bacteria in all yogurt: Lactobacillus bulgaricus and Streptococcus thermophilus.
@@vanillaglue that's what I'm doing mostly thanks for the intel :)
I wonder about liposomal resveratrol instead of yogurt. I blend mine up with coconut oil and lecithin which is suppose to make resveratrol absorb better.
I have no way of knowing if it works though...
The important thing is that it be taken with some fat.
It works. You have less and less money every month.
Guys check out tony the herbalist on utube , his grapefruit red onion ginger formula and the red wine garlic and abscorbic acid formula both u make yourself ...you might be get a big surprise on the effects,,,I am indebted to this man best of health to you 😀
WHAT does the interviwer takes, I want that.
Probably a couple hundred kilos of iron daily.
looks like he is on weed😂
Abit of Test.....just a guess
Steroids
I am 73 and I get spaced out on Reservatrol. Help.
me: i make it myself
also me: it's not mine actualy
Whats forman
Eating a little high fat yoghurt does break an autophagy fast but shouldn't affect insulin too much ... people fast for different reasons. It would be better to add the resveratrol to olive oil or another 100% fat .. as that generally doesn't trigger insulin ... whereas yoghurt does have some protein in it, which should break a fast ... however a couple of tablespoons is not a lot
☑️☑️
awesome
Does anyone know what he means by putting his yogurt in the oven on defrost?
Probably Puts in the microwave on a low setting (ie defrost) to heat it up to body temperature
I wish he’d say what brand ?
I take 2gr of extruded berberine, 1 gr of NMN, 1 gr of trans resveratrol, 20 mg of cycloastragenol, 300 mg of ubiquinol and 20 mg of PQQ
He said and NAD booster. Not NAD. He's talking about MNM.
Can Berberine be an alternative to metformin?
Yes.....it will work.
@@marknel3863 Similar to metformin regarding longevity?
@@lazi21 That is what is claimed. A 500mg dosage 2 to 3 times per day will give the same effects. Some health sites claim it's better than Metformin as it will not cause lactic acidosis. Here is a med paper to have a look at to help you make an accurate decision
www.ncbi.nlm.nih.gov/pmc/articles/PMC5839379/pdf/oncotarget-09-10135.pdf
@@lazi21 What is nice about it is you don't need a doctors script for it, you can get them at health stores, online etc...very easy to get
@@marknel3863 Finding a reliable source for any vitamin/supplement is a bit of a crapshoot; especially on Amazon. Know of any reliable sources? I wish an independent lab would test and post levels of ingredients.
How do I get my hands on a gram of diabetes meds???
@Nuby29 really I don't have diabetes though...will he still give it to me??😃
@Nuby29 thank you x
@@fatimaarcaro8979 eat a banana before you give blood, say you didnt eat anything. tadaa u have diabetes xd
@@Bankai90 well thank you very much yes.😃👏👏
Does aspirin slow down cancer growth or not?
So the metaformin he only takes because of his diabetes? Or are there any studies on it that it is antiaging?
ppl can correct me if I am wrong, but if I remember correctly it regulates the insulin concentration in the blood flow and cell metabolism, which in turn prevents aging (not that much but every thing adds up).
@@erikavivanco8473 Thanks a lot my dear
Metformin is the first and (AFAIK) only drug to be evaluated by the USFDA as a Life Extension drug.
Check out the following research articles:
www.ncbi.nlm.nih.gov/pmc/articles/PMC4772077/
www.ncbi.nlm.nih.gov/pmc/articles/PMC5943638/
www.ncbi.nlm.nih.gov/pmc/articles/PMC6052468/
www.ncbi.nlm.nih.gov/pmc/articles/PMC3898468/
www.ncbi.nlm.nih.gov/pmc/articles/PMC4066537/
www.ncbi.nlm.nih.gov/pmc/articles/PMC5892694/
pubmed.ncbi.nlm.nih.gov/21882902/
pubmed.ncbi.nlm.nih.gov/30255224/
pubmed.ncbi.nlm.nih.gov/18728386/
pubmed.ncbi.nlm.nih.gov/21084729/
@@erikavivanco8473 yep preventative care its called, aye
Dats it?
3 spoonfuls of fatty yogurt= fast broken IMHO
agreed. fast = water only.
checkout sten Ekberg ..he is a absolute genius with all this kind of diet and fasting stuff.
NAD booster and not NMN? Why did he stop NMN?
nmn is a nad booster
why does not ds take metformin at night？
No fasting for me.
How can I get Metformin
ruoh anna forrof Ballllab doctorrotcod SuckkcuSS
Prescription. Many doctors are aware of its benefits and won't hesitate to write one.
@@rogerbritus9378 many side effects this drug cause , grapefrruit have same effect , cyleon cinnamon have same effect and no side effects , people who believe in pills fail , why dont you just do keto instead no need for metaformin and eat once or twice a day
@@rogerbritus9378 I’ll ask
@@damiandamiano3651 Thanks man, you're right on. Funny thing is that I've fed my dog basically keto food - not much, and only once a day, for 16 years now. Her favorite snacks are cheese or frozen broccoli, that she chews on with her strong, white, and plaque-free teeth that were never professionally cleaned. Except for vaccines, I have NEVER taken her to the vet for any sickness. But I also give her DAILY 5 fish oil pills, plus one each of chondroitin/glucosamine, quercetin, and lutein. She's healthier than I am.
my brain likes to simplify things for better or worse my take is after some googlin/skimming the comments, don't overeat, avoid meat and sugars, if you're not tryna spend on pills hit up some berries and get the boujiest yogurt but only have like a spoon ful or two in the morning unless you're hardcore than eff food.
also coming form the virt channel it's like be cold or hot, basically be uncomfortable until it's normal especially if you in the states lmao.
Its only a little bit of yogurt, last time I checked fasting meant no food. 🤣🤣😳🤔
@vvenomm 492 Yeah means no food 16 hours a day
@@siZeDcuBe exactly. fasting = water only.
@Apollo Sun by that logic, it you ate, lets say 1 tic tac per hour, for your entire awake day, you would not trigger any autophagy.
Which is of course not true at all, because otherwise you die.
If you need more energy than youre eating, autophagy triggers, that simple.
There is no "breaking" a fast because you glucose levels would plummet extremely fast by just eating a tiny thing.
bobe sinclar
People bitching in comments > No one forcing you to take anything. Live your life as you see fit. Stop whining .
Can't believe David Sinclair takes a statin
Jane Hicks . I can’t believe it either. Statins dry up all of the Co-Q-10 in your brain and heart and THAT can kill you! Statins can mimic the symptoms of dementia, memory loss. A friend of mine was on them and her memory became really TERRIBLE!! We thought she was descending into Alzheimer’s Disease! I got her off of the Statin drug she was on and had her supplement with Coenzyme Q-10 and her memory did improve! Dr. Sinclair wants to live a long, healthy life and yet he’s taking Metformin and Statins! Doesn’t make sense. Vitamin B-3, Niacin, works as well if not better than Statin drugs without the side effects so why take Statins??
Yeah, I heard him say that on the Joe Rogan show too. Joe said something like "Dude, why are you taking statins? They are really bad for you!" David replied that he knows how bad they are, but really high cholesterol runs in his family and he is worried about that.
@@JB-pk1vc then he isnt really all that smart imo.. Our bodies make cholesterol.
Met for min is not a statin
jorge duran He said takes Metformin and takes a statin
The text says "I take Mike Foreman every morning" What we should understand is 'I take Metilformine every morning". Maybe it is clear fore natives, but non English speackers could become confused.
Great advice but this stuff is impossible to get if you are not a doctor and have deep pockets.
Yes, 1gram NMN /day cost $600/mon. on Amazon!
@@MartinSage it sounds so much, but if it honestly would make you live 20 or even 30years longer in great health, suddenly it wouldn't seem that much xd
Typical poverty mentality. But somehow Joe six pack will keep finding money for all those beers, cigarettes, and lottery tickets. Oh yeah and for expensive phones and BS entertainment.
If somehow there's just never enough money for making a real investment in yourself
I pay less than 40/month for 300mg/day NR. Don't need more than that if you are under 70. Don't need it at all if you are under 40.
What if you get as much as you can of the other ingredients than the NMN, would you still slow down aging significantly? I'm retired on Social Security and below the US Federal poverty line. In the video they say it's not just for the rich people, but seeing 1gr of NMN a day is $600 a month, wow!
He is 50 years old and he has zero grey hair? or does he dye his hair?
i think in the video he is implying it is natural. No dye.
@@johnlogie1860 I started taking NmN after seeing this video (1 month ago), i am hoping that my grey hair will go away.
Eating yogurt, even a couple tablespoons IS absolutely breaking a fast. Anything other than water is breaking a fast.
Everything under 50kcal won't break a fast, look it up on your own
@@MyWoWCat 50k? Are you allright
@@johncoe6304 50KCal means 50 calories, now are you alright?
This is technically true, although 50Cals will be burnt off in under an hour. However, any carbs or proteins will temporarily switch off ketosis and autophagy (in longer fasts). A further ‘danger’ of even a small meal…like a yoghurt…is that it will re-energise the digestive system which during 48+ hrs fasts is pretty much shut down.
Wait, isn't this the 'nmn' or 'mnm' guy? Why doesn't he mention THAT
He says he takes a gram of it a day, that's what an NAD booster is