ASPIRIN & Medical Flip Flops | Reversal, Replacement, Evidence Expiration Dates | A doctor discusses
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- čas přidán 25. 07. 2024
- For folks interested in Medical Reversal
read the book:
www.amazon.com/Ending-Medical...
Vinay Prasad, MD MPH
Hematologist/ Oncologist
Associate Professor of Epidemiology & Biostatistics
www.vinayakkprasad.com
Host of Plenary Session Podcast
www.plenarysessionpodcast.com
/ plenarysession
Read our academic papers here:
www.vkprasadlab.com
Follow me on:
Twitter @vprasadmdmph
Yeah, I can think of another example. Can't talk about it, of course.
I'm so in love with your reasoning. The arrogance to believe that biology is a simplistic matter has caused a lot of suffering in the past. It's ever-changing, highly complex, interconnected with countless factors in our environment, and we will never fully understand.
How can you not like Dr. Prasad's approach to various topics in medicine? He's amazing!
Very interesting. I liked the example of the tech person entering biomedicine and saying "why can't we just do this to solve the problem?" I believe this highlights one of the biggest issues facing us today in all aspects of life. So many "experts" love to zoom in on the problem, create solutions, then step back and cheer themselves on. Like the body, however, the world is so much more complex and making a change in one area causes the rest of nature to respond and try and balance out that change. Too often, this leads to unforeseen consequences. When those experts are not inclined to step back and see how their "fix" actually works in the broader world, we often end up running headlong towards brand new problems. The only hope is that those new problems do not become worse then the problem the "fix" was meant to address. I pray that micro problem solving can incorporate macro level observation in order to return to some sanity and real, sustainable progress.
If they are looking for a certain reinforcement for their desired outcome, they're going to find it, search for it, even dig for it. Does it mean the outcome is correct? Probably not. Objectivism has given way to subjectivism.
🐂🚽 If the billions and trillions spent of Franken-fruit and war was spent on improving human life worldwide with proper food, shelter and water, there would be zero need for franken-science
@@bullsh3176 The plan is Not about benefiting the people; it’s about benefiting SOME people, and the deeds are not about humanity, they are clearly, about power and greed instead!
Yet we have *soooo* much raw data locked into the new medical systems like EPIC. There's gotta be a good way to utilize it and have it tailor itself to individual patients.
For an example, I often have atypical labs and symptoms of much larger problems. Yet if I don't meet the checklist of certain issues, then I'm completely dismissed.
I was part of a randomized aspirin study that recently ended looking at dosing. Coming from decades of aviation experience focused mostly on preventative maintenance through trend and failure analysis, I was amazed at what I learned regarding something as simple as what dose to take in regards to cardiac care. The total lack of any sort of evidence, or data basis for the dosage I had been taking, or even the effectiveness of taking it blew my mind. It's fantastic to see a doctor pushing for real science, instead of using the term science to push an educated guess
Aspirin has been suspect for awhile now due to excessive bleeding risk and there is no excuse for this reversal coming so late. Thanks!!
"a bit problematic"? I believe it's called "overt and purposeful medical malpractice punishable by law"
100% agree
Thank you Sir...
And... Let’s go Brandon !!!
This Brandon guy sure is popular...he should run for President I'm sure he'll definitely get 81M votes.
Lets go Brandon!
Ok. This guy is good. I’m a doc w small experience in RCTs and heavily involved w real world evidence. Much appreciated this.
Never forget to “follow the money” …..
“And I describe how the pharmaceutical industry uses its immense wealth and power to co-opt nearly every institution that might stand in its way - including the US Congress, the FDA and the medical profession itself.”
From : “The Truth About the Drug Companies” by Marcia Angell, MD
That´s why I am always sceptical about doctors wanting to do procedures on me. I would always rather not do it if it doesnt seem too dangerous to not do it. Like e. g. antibiotics are given out like candy without even checking whether or not it is actually a bacterial infection. You kill lots of bacteria (if bacteria are "causing" the infection), yes, but also the ones that help you to digest and stay overall protected from bad bacteria.... Or like have you ever thought about pain killers or anti-depressants? They are meant to take your pain away, but actually the pain points to a problem that doesn´t go away by itself often times. So if you take them long term or very frequently the body will potentially start to make you more sensitive to the pain and try to get that poison out of your system more efficiently - the pills stop working.
I find it very interesting that with the new vaccines though no one is discussing that there could be long term effects or even (rare) undetected side effects that would make the vaccine useless for some age groups and for some uses. (E. g. the might help healthy 80 yr olds to prevent severe disease and death but the might not be appropriate to be used on young adults to prevent the spread in the older population because more live-years will be lost in the young people than saved in the older population overall)
Citation?
Hi Dr V, let’s continue to keep up the conversation.
A critical point you make (and which is almost certainly true) is that most designed treatments don't work. I don't think that insight has really been internalized by many doctors and Science communicators due the American pressure for optimism, the pressure to show results for career purposes, and the selection bias of always knowing about the treatments that were successful and rarely encountering the failures.
I have a few different chronic issues and the place where I've personally seen this problem is with severe headaches and migraines. I went through 6-7 neurologist before finding one that would
1) not treat me like a medical experiment
2) not get pissed for me asking for a *good* study on the medication that they want to give me
3) as a stable bipolar patient, not consider, at, all, psychotropic medications used off label or with next to no real proof
Migraine and headache management is treated like witchcraft and it needs to stop.
You stated "with aspirin we discovered it didn't work in current patients." Aspirin works but the issue is risk benefit for individual patients. If you eliminated all the people > 70 eating once a day. You'd eliminate siginificant GI bleeding from the consideration. I would say if a patient has metabolic syndrome they likely have atheroclerosis. This large subset of patient has shown low dose aspirin doesn't work because they should be on full dose ASA . I think if a patient has been on a statin with an LDL < 70 for several years their atheroma are mostly stable and most likely don't benefit enough from ASA. I think the mistake is deciding aspirin doesn't work for primary prevention in general. Aspirin has probably been a bad idea for the general population all along. But I think this reversal is ill advised for many subsets of patients.
Thank you for making this accessible to the layperson. Learned more in 16 minutes than any full term science course.
Brilliant. Wish you ran the FDA, CDC, or NIH
Very interesting concepts I had never really considered. Thank you,
You are perceptive! Our very existence is a testimony to the intricacies of being a living, thinking creature. We are too complex a system to easily manipulate and repair.
Your critical thinking is "exquisitely" evolved. Your passion for finding the reality of a situation is so lovely. Did you write for Medpage today? I've been a paramedic for 20 years and have seen medical reversal a bit over time. Sadly, it wasn't hard to see that many pre-hospital practices were going to be reversed. (a quality study in the prehospital environment? 😂 I dont even know how that works) How does one continue to labor under protocols that are obviously harmful, knowing that many will be reversed at some point? I hate hurting people, it goes against every fiber of my being.
Non-sequiter - How many "covid-kidney" deaths are actually pharmaceutical poisonings with pressers, anti-virals, and other nephrotoxic drugs? This whole thing makes me so sad.
I saw some kidney effects in our coworkers vaccinated with Moderna early on, a day of dark urine and tenderness, almost like Rhabdo. Intramuscular injection, Muscle cells being the ones that express the protein? Myocarditis? Off target immune reaponses? Anyways, you are great.
I hope you know that people like yourself are precious to humanity. Thank you for speaking.
The problem with "clear standards of evidence" is they have a profound impact on profits.
Your content is superb. Excellent material and wonderfully articulated.
When asprin was initially found to be helpful it was not considered to be in "competition" with other drugs. Now that cheap, safe asprin is in competition with other drugs and other drugs may be more effective (not necessarily more safe) they will recommend against aspirin. They also recommend against vitamin D in some studies.
There's a recent Israeli study that came out that it helps with covid probably why the compromised MSM are shilling against it.
@@fuzinonzlot Exactly and low dose asprin is also found to be effective at preventing some cancers. Lynch syndrome being one. Also lowers risk of vaccine blood clots. They conveniently banned natural NAC from OTC recently. It was found to benefit covid and vaccine risks. NAC depletion leads to cytokine cascade damage from ROS during covid and vaccines. It's as if they want as many chronic diseases as possible to develop after the vaccines and covid with only pharma recommended treatments being acceptable.
Honestly, as a lay person reading and researching, I stocked up on low dose aspirin for my family way before it was recommended by anyone. Blood clots are dangerous and many take low dose aspirin for years per doctor's orders.
I don't feel like they aren't exactly saying that it's of no use. Just that we need to look at the whole profile of a person before prescribing things.
Also, statins are dirt cheap, just not OTC. You can definitely hurt yourself with asprin. It is toxic to the liver.
As for vitamin d? You can overdose on it easily with supplements and most people are not deficient. Unlike myself who is homebound with chronic illnesses and such, I have to be tested every 3-4 months a full metabolic panel and for vitamin d deficiency. My vitamin d levels barely hit normal and that's with daily supplements at 1k iu
It's honestly awesome to see you guys understand the MDs flocking to Functional medicine
The one i asked to see recently doesnt take insurance
Hi Dr. Prasad . I like the confidence you display in your talks even though I don't understand most of it and your pace is faster than anyone I've ever listened to and that I enjoy your talks . I don't understand most of the Sciences nor am I a medic . I'm a patient and use Aspirin and have found it with unexpected useful benefits . It was prescribed by my Doctor many years ago and is based around medical problems in my family history . The surprising benefit is that the extreme scaling of the skin around my ankles has turned back into skin and no longer resembles dragon scales . I don't how ever like the bleeding that happens with every scratch . Just thought that I'd let you know that I think it Aspirin has benefited me . With Regards . Cheers
Ben Shapiro might talk faster!
This process applies to fishing, cooking, working out, investing, etc. It's basic fundamental principals to experiment almost every "what we call rational hypothesis," we know thus far. Apply it using various variables and duplicating certain patterns and behavior. Only someone who is after something selfishly and degenerate would argue a different model, of course we have to accept the fact we don't know everything there is to the world.
Wow. Do. Not. Stop. Thanks for your great work
Finally a medical researcher that actually thinks about these extremely important issues!
Thank you. Informative as always.
Well... you are being very gentle and nice about it... please talk to us more... thank you.
Yep, they go ahead and implement it! 1:09. Too funny, I wish it weren’t happening now. 4:08 don’t forget keeping the Placebo group during the trial as opposed to another infamous recent trial. We need to do credible studies, 13:59, excellent ! You have a brilliant presentation here and consider the retrospective data and the many new Variables, many factors intrude on the studies. Well done.
Great topic. Thank you!
Brilliant!!!
I loved this analysis. It reminded me of an online conversation I saw around RDV for vitamins. A new doctor was trying to figure out a way to fix global malnutrition and wanted to know what the RDV was for different vitamins/minerals regardless of calories. All of the more experienced doctors patiently tried to explain that's not how it works because it can be affected by everything from age to activity levels to menstruation and gender. But this new doctor arrogantly told the others that of course it was simple, just no one had done it yet, and insisted there was a neat tidy solution that would change the world. It was a sad but telling thing to see.
its not economically and logistically feasible, not a discussion about it not being effective, bc it definitely would work
Another reason why there are medical reversals: too little research on prevention, and poor evolutionary understanding and logic in the medical field. Treatments are often too far after the fact, so most cures are a bit of a hack.
Agreed doc! One entity that evaluates medical practice is the Cochrane group, too bad they were put on a leash a few years back.
Cochrane reviews are considered to be very reliable but is it? Has anyone really looked at how effective they really are, properly?
This is an example of a good MD. Thinks things through, is honest about results and where questions have yet to be answered. Also understands that there is danger in assumptions and limited testing. Sad this type Of MD is so rare. Millions of us will never go to a corporate affiliated MD or a hospital again.
It took nearly ten years to reverse the use of acid blockers for treating peptic ulcers after the discovery of H. pylori bacteria as the cause.
Very nice video. I remember how early goal directed therapy in sepsis was considered gospel when I was a medical student. My guess is the PRISM study failed because the style of "usual care" changed over the years such that all ICU docs would aggressively hydrate and reverse hypotension early regardless of whether or not it was "goal-directed." What matters is what you do, not why you do it. However, there are many treatments not proven by randomized controlled trials that are likely effective. One example is rituximab for neuromyelitis optica. Given the impressive case-series data and our clinical experience, should we stop prescribing it? Should we prescribe Uplizna which has a nearly identical mechanism of action (targets CD19 instead of CD20) and is much more expensive and doesn't have a decades long safety-history just because it has a randomized trial? I certainly agree that a randomized trial should have been done two decades ago. Now, I would question the ethics of randomizing someone with neuromyelitis optica to placebo. I enjoyed "Malignant," and you have definitely earned my audience, so I will read "Ending Medical Reversal" soon.
Does everyone have the same level of disease where a double blind can't be safely done?
@@lucrezaborgia I'm not sure what you mean.
@@DrBrandonBeaber I looked up the condition you mentioned. From what I read, not everyone has the same level of dysfunction and it appears to be intermittent for some people. Could an ethical study be done on less severe cases like mentioned elsewhere?
@@lucrezaborgia For neuromyelitis optica, it is highly variable and attacks can cause devastating permanent disability even in someone who currently has a low level of disability. In my opinion, it is unethical to do a placebo-controlled trial.
Tiny effect sizes for known benefits bump up against unknown effect sizes for unknown risks (as these risks become known).
Dr. Prasad, can you please link the research studies you refer to in the description below? It saves us time and covers your bases. Great work, really appreciate your objective views on medicine.
God bless you dr prasad
I appreciate you
Thanks bro
How frequently do these reversals happen in this last decade? As usual , great discussion!
21% of all FDA approved drugs are either taken off the market or given black labels for the most dangerous side effects years later.
So to answer your question, quite frequently.
He and Dr Z are awesome
Objectivity is a basic requirement for "science" to be science. Industry run RCTs (and there are no other kind) are anything but objective. We should stop mentioning the RCT and science in the same sentence.
I don't understand how RCTs are any use other than looking at the data to design double blind studies
Great info
I'm curious to know your opinion on the flu vaccine every flu season? Isn't it only effective againt the stran from the previous season? Thanks for your videos & great unbiased perspective!
I hope you can also start uploading content on Facebook .
I think that we should make a distinction between medicine as science, and medicine as a practice. Science should be rigorious. If not, then we build a tower on weak basis. In practice, we are in war.
We don't have the time to wait for clinical RCT double blinded trils to be done and being peer-reviwed, and thus, we have to make decisions based on weighing evidence for and against under high uncertainty. I agree that observasional studies are not very strong evidence, I disagree that they are in general negligible. Correlation does not necessarily imply causation, but still from the point of Bayesian calculations, they should be treated as non-negligible evidence. The main important thing is to remember to keep the weighing updated all the time.
Thx, we know! Experiencing DEADLY side effects right now!
I'm glad you identify with the medical establishment - as demonstrated by your constant use of 'we' - but I think that is the wrong pronoun. We don't have the ideal medical establishment your model for curing medical flip-flops depends on. Instead there are a variety of medical processing streams controlled by assorted companies and industries and increasingly managed by captured government regulatory agencies.
The flood of drugs that may or may not work is a symptom of the disease. Double-blind placebo controlled trials may treat the symptoms, they will not cure the disease. Public health agencies do not serve the public (they serve the corporations that fund them) and are not concerned with public health (drug profits does not equal health). That is the disease that needs to be cured - and a healthy public health apparatus would go a long way to reduce medical flip-flops.
Exactly. The best thing is to keep yourself as healthy as possible and stay away from the kind of doctors who push drugs.
forgive this, but does anyone have a time-stamp-ish for when aspirin enters in here?
As usual, this doctor has some worthwhile ideas. However, like SO many wonderful ideas about fixing the major issues in medicine, NOTHING will change. The reason I say this is despite many of our complex issues in society having tenable solutions, none ever truly move forward - at least not for the major issues (Climate Change, Extreme polarization, go nowhere politics, Medicine losing it's way, poverty, etc.)
I am not merely pessimistic when I predict that nothing will change. I'm saying it because many of the problems in medicine are due to an extremely perverse incentive system. Medicine has become inexorably bound to big pharma, the cult of evidence-based medicine and the all-mighty dollar.
Big pharma is like a rapacious juggernaut that has one endpoint; more $ for its shareholders and its leadership. The problem is, they are already one of the most obscenely profitable sectors in the economy. Why is that a problem? Because that means they have a clear incentive to piss on old drugs (no profit due to being out of patent), denigrate natural therapies and always exaggerate the benefits of novel drugs.
Given their enormous lobbying power, they entirely bend government to their will. Therefore, when they produce a treatment that's more based on marketing than credible science, they get a slap on the wrist. But they are never "fired." Just like military contractors are known to chronically defraud the taxpayer and provide BS services. They are simply just given contracts by the government over and over.
But coming back to medicine, many of the current pharma companies making the vax's are either currently being sued, or are continually in a process of being sued. Pfizer I believe was recently sued for some billions of $'s, paid it and continue along. For a company that is raking in billions per month, a billion-dollar fine is a slap on the wrist - merely a cost of doing business.
Then you include the revolving door of big pharma, as well as pharma funding the regulating bodies. Well, you can see that the fox guarding the henhouse is not conducive to a science of integrity or good healthcare.
So as usual, this doctor has some great ideas, but without a true change to the incentive system, these ideas simply have no chance. I'd love to be wrong, but I've been following the issues with iatrogenic death (meaning medicine caused death - long one of the leading causes of death in the US), polypharmacy (giving patients many drugs @ the same time with no true scientific way to know if this is either safe or effective) for more than 20 years.
Things are not getting better; they are only getting worse. As an example, a recent study showed that 1/3 of FDA approved drugs/treatments had to be either taken off the market or given the fatal "black box warning." Meaning, that despite years of safety trials, 1/3 of drugs were found to be more harmful than beneficial. How's that for a vote of confidence in a regulating body? Many patients were harmed/killed by these preventable mistakes. In addition, the FDA receives a goodly portion of its funding from big pharma itself an obvious conflict of interest.
So, unless medicine ever divests itself from being bound to $, big pharma and the like, it will never be reformed in a significant way. Like I said, hope I'm wrong. However, the current system has such profound momentum with seemingly no true awareness of the root issues, that it's highly doubtful good ideas like this doc's will ever come to pass.
Peace
But remember the first part of revolution is realization.
Thank you
Evidence doesn’t expire. Methods might. But evidence doesn’t.
Edit: Unless of course the methods previously used to obtain evidence was found to be improper.
reverse the reversal ?
Trust the science
Your summation at the 15 min mark is the truth that too many people are missing . Prevention and living a healthy lifestyle is the key . Here's a randomized control study for you ..just talk to anyone that's healthy and over 100 yrs old !
First. Great work sir.
As doctors we always feel we need to do, something, when ‘ masterly inactivity’ is the treatment of choice!
Pretest probability, based on prophecy and faith of eager scientists, which progresses at warp speed from production to approval, is not the same as: conducting ethically credible studies. My question is: How some scientists dare claim that a product (the result of warp speed) be tooted as “safe and effective” and then be mandated? This is not only a clear candidate of “product reversal”, it is “scientific process reversal”. Thank you for your ethical scientific perspective.
The paperwork and production was done at 'warp speed'. Not the testing.
@@lucrezaborgia I apologize, I must have missed the part of the study, which specifies the long term effects!?
But is the aspirin thing really a flip flop? The older evidence still applies to the patient populations that would be the same as in those studies no?
EMS had a near-universal mandate of backboarding (and thus torturing patients) for almost 50 years until someone decided to evaluate the issue.
That Mr. Show sketch, the Limits of Science, never gets old for me. And in this case, I always think about how much Dr. Prasad's voice reminds me of Tom Kenny's. It all comes together in this sketch: Tom Kenny as the wizard who develops a hypothesis in his dreams, Bob Odenkirk narrating how science works (almost in Dr. Prasad's words, but with a medieval twist, of course), and David Cross's "modern man" asking the 3 questions... czcams.com/video/KGXQiEqVj88/video.html
We can't give aspirin to under 16's due to an SAE of less than one in a million.
But you can mandate an EUA therapeutic with little to no trial data with a known SAE potentially leading to a life changing/shortening event of 1K -5K in under 16's.
Is this what your getting at?
This is exactly why the covid vaccines make me hesitant. This is the phase 3 trial for these specific vaccines but without the control group. There is no long term data for serious health consequences.
they are also claiming since Jan 2021 none of the deaths are v@x related. Something is definitely wrong when they don’t actually want to know what happens pos5 injection during the trial period.
On the topic of flip flops, I think of women's health issues like pap smears moving to every 5 years and self-breast exams not considered to be helpful. Oftentimes, a doctor just glosses over new policies but doesn't stop to explain why. I happen to ask follow up questions because I'm truly interested but I think most women just accept what they hear. And in my mind, I always wonder if something is necessary and does insurance want to get out of paying for it?
👍
Why have a randomized study when simply implementing a new drug is so much more profitable?
It’s all about the money, working in the medical field for 35 years, doctors are taught to band-Aid the symptoms with pharmaceuticals drugs not to find the cure or why the patient is sick.
And only the drugs from companies that send them on vacations
@@truenokill they aren't allowed to do that anymore.
I like how you think, but in this day with politics and mainstream media and the internet, the ideal model is often corrupted.
Much like PRP Vs The joint replacement industry
Remember the Scientific Method?
I think what you indicated here is that no matter how well a study is, data from it can become obsolete. And therefore we either need new studies repeated regularly or we need to find a different way to practice medicine? Ohhhhh boy! Science is deadly if not careful! (How many people have died from the bad sciences on cigarettes, saturated fats, trans fats, sugar, glyphosate, DDT, etc)?
"welcome to complex systems.."
"these types of data have such poor credibility, it's almost like no data at all"
WRONG
Having poor credibility data gives the illusion of certainty or provides false and misleading signals. It can lead to worse outcomes. If I am driving a car in NYC, but all I have is a map of LA, that is not the same thing as no map. No map might be better.
They literally FUDGED the blind trials.
Only using RCT as the source of info and knowledge is fraught with significant real world problems. It should never be the be all and end all.
The same fallen angels that gave the world nephilim, are now giving the world their version of science.
For centuries, scientists have been using scientific method, trials and errors, and studies done by more experts and debunked some of the errors which is a good thing.
Approximately 7:00. Should medical practices come with an expiration date?
They should, but they won’t…..especially when there is $$$$$$$$$ coming in from those medical practices. What company really wants to know how to DECREASE one of its streams of revenue?
Go back to disallowing marketing?
@@lucrezaborgia Not sure. The solution is elusive. I do know that I can’t even have the TV or radio on during a commercial without some erectile dysfunction or low T as coming on and having my kids ask all kinds of questions…..and that’s small potatoes compared to drug companies and drug reps having docs in their pockets pushing their products.
@@quengmingmeow my mother manages a cardio practice. We have talked extensively about how drug reps function over the past 25 years. It's not as easy these days for reps to do what they used to. Though, my neurologist doesn't like being 'educated' by them and outright hides from them when they come to the practice he's part of.
Your own body and mind is what heals you. Medicine can temporarily aid the body by targeting say a bacteria with an antibiotic but it is still the body that heals itself. Medicine that regulates a condition say HPB, diabetes does not heal the condition it simply controls it…..usually with side effects. So not sure what the aspirin is doing outside of thinning your blood…..however what else is it doing taking it every day?? Next time you get a headache before you reach for a pain killer try neck stretches and deep slow breathing. All painkilllers are not friendly to your liver…..my friend broke his leg some years back and took too much tylenol and fried his liver. He had to have a transplant
You clearly have never experienced allergies or mcas...
Tylenol is a classic example of an OTC med that is very dangerous.
@@lucrezaborgia on the contrary. I have lived with MCS for 35 years. My allergic asthma has sent me to hospital in the past . I have had many years of trial and error and found a few herbs and some supplements to support my health. I have tried western medicines and found they only made my condition worse. Everybody is different except for my statement….the body and mind is what heals everyone….
@@lucrezaborgia most over the counter meds as well as a number of prescriptions create long term damage
@@deborahhebblethwaite1865 herbs are not going to control my histamine response. Mast cell activation syndrome is not the same as multiple chemical sensitivity.
I couldn't afford the aspirins anyway. Probably saved my life.
Simple---GREED.
P.S. card
Thx VP!
It is not one fit all... that is why colonies like Canada and more other's created... mandate...force...u are here on our terms ... not you .
You draw the incorrect conclusion that surgical masks work in Bangladesh when other factors are the reason for the results. Surgical masks were ineffective in Canadian long term care homes when trained staff were using them.
What were the other factors contributing to success? Do you think the narrative was twisted by reporters?
@@vivaciousom5347, if the narrative was twisted by reporters, perhaps there simply was no success. The same result could be achieved by a government reporting a falsehood.
Contracting the virus and the eventual outcome from that is dependent upon many factors, one of which is a person's health, and all of 12% of the US population is healthy. The other 88% suffers from some degree of metabolic syndrome. The virus adversely affects those with metabolic syndrome, particularly the overweight and obese.
The problem with this "pandemic" is the lack of real information. It's frustrating the wealthy nations have done such a poor job of collecting relevant metrics.
It's also frustrating that so much emphasis is placed on the vaccine. Some vaccines work exceptionally well, others offer very little efficacy. The Pfizer vaccine is touted as having a relative risk reduction ratio of 95%, but their trial data showed their absolute risk reduction ratio was only 0.7%. Neither of these numbers is meaningful because the trial has no idea how many participants actually encountered the virus. A study [ Increases in COVID-19 are unrelated to levels of vaccination across 68 countries and 2947 counties in the United States
PMCID: PMC8481107 PMID: 34591202 September 30, 2021 S.V. Subramanian and Akhil Kumar ] suggests regions with higher vaccination rates are experiencing higher infection rates, now called "cases" than regions with lower vaccination rates.
What do we know?
* masks are not effective.
* ventilation is effective, the better the ventilation, the more effective it is, outdoors is best.
* vaccinated or not, if you do not encounter the virus, you do not get sick.
* vaccinated or not, if you encounter enough of the virus, you get sick.
* vaccine tells your body to be on the lookout for a pathogen; your immune system is responsible for eliminating pathogens.
* some people have well regulated, effective immune systems, others do not. Having sufficient vitamin D makes a big difference to the outcome.
* magnesium, zinc, vitamin C, etc. are helpful in your battle with the virus.
* it takes about 5 days for your immune system to stop the virus from replicating.
* the second week is critical, if your immune system is well regulated, your immune system cleans things up. If your immune system is not well regulated, it kills you.
* politicians want a quick painless way for an unhealthy population to overcome the virus.
* the available vaccines are not magic bullets and do not work very well in unhealthy bodies.
* there is a lot more required of epidemiologists than just counting who is a case and who is vaccinated. Before you can tell if the vaccine actually works, you have to measure all of the confounders and provide that data as well.
@@Ron_the_Skeptic I appreciate your reply. I agree with everything you are saying. Are you a High Intensity Health viewer? I think you’d like that. Mike digs into many studies and is a proponent in doing everything possible to strengthen one’s immune system.
@@vivaciousom5347, I am familiar with his channel.
Mike who ? What channel.