Is it safe to use statin in the fatty liver with Dyslipidemia and raised ALT?

Yes, it is safe in most of the cases. Presented by Dr. Mohammad Harun Or Rashid. Assistant Professor Colonel Malek Medical College, Manikganj.
In a systematic review and met analysis, including 22 studies with 2345 NAFLD patients. In all interventional studies, except one, patients had raised ALT, AST and GGT at baseline. ALT, AST, and GGT were reduced after statin treatment with a percentage mean difference of _35.41%, _31.78%, and _25.57%, respectively, suggesting liver safety of statins in NAFLD patients.
Ref: Pastori D et al. Statin liver safety in non-alcoholic fatty liver disease: A systematic review and metanalysis. Br J Clin Pharmacol. 2022 Feb;88(2):441-451. doi: 10.1111/bcp.14943. Epub 2021 Jun 28. PMID: 34133035; PMCID: PMC9290532.

[@it.ibrahim95]

Good