Lyme Disease and Autoimmunity, Rob Lochhead, PhD - Lyme Summit 2023
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- čas přidán 9. 10. 2023
- Lyme Disease and Autoimmunity, Rob Lochhead, PhD, Medical College of Wisconsin from Lyme Summit 2023 hosted by CNY Lyme & Tick-Borne Disease Alliance and SUNY Upstate Global Health Institute.
Please have Dr Steven Phillips and Dr Joseph Jemsek share their findings.
I love medical science, biology, anatomy, immunology, physiology etc…but it is extraordinarily difficult to think clinically when what you are seeing has been completely debilitating within you. It has contributed to years of my life being missed
What an overwhelming amount of information. I have chronic lyme. I was diagnosed with a positive lyme two years after symptoms. I am still experiencing extreme fatigue after being on 29 to 30 different antibiotics.
My mom has been on treatment for about 8 months and been on 5-6 antibiotics so far. The fatigue is still the thing that affects her most.
How do we treat Lyme arthritis after we have exhausted antibiotic treatments? Do we use immunomodulators?
Can this include inducing diabetes as isn’t that an attack on pancreas? My mom never had any problem with blood sugar and then now a year after their Lyme symptoms started, she’s had to start on insulin after trying other medications to reduce her blood sugar that would not work.
Thank you for a fascinating lecture. Very complex. I must admit though, speaking as one who actually has Lyme arthritis, I have to disagree in part. My father was an immunologist, so I am not entirely without knowledge. As a Lyme patient, I am driven by a desire to completely understand my condition. So, what I must say, is, I do not for one minute believe in the concept of auto immunity. I think that what you are witnessing is not a wayward immune system destroying it's host but rather the ongoing progression of the infestation. After many years with this disease, I still have all the symptoms you show in your slides. I think that this is due to the actions of the parasite, very much active within my tissues. So my body's 'auto immune' response is actually the normal response to inflammation. My cytokines are reacting to a needed demand to deal with the invaders, NOT fighting ghosts. In these long Lyme cases what you have to do is inspect the victim's spinal fluid for signs of spirochete activity. Not assume that the antibiotics have done their job and declare " why is the body eating itself " . No , it is still mounting a rear guard battle for homeostasis. Doing what it is supposed to do. One should investigate the work of Alan Mc Donald. He was a pathologist who had access to dead subjects. He found spirochetes everywhere ! Significantly in spinal fluid. They are to be found in synovial fluid too, I am sure. I am sure they are still wandering about my body. They have this ability to wander and to disguise themselves and to hide under a biofilm. Therefore I say, NO, not auto immunity but self survival.
NB I also have Neuro Lyme Disease . Not nice.
This is fascinating. I wonder if anyone can answer the question of: When he talks about b.burgdoferi here in this talk, is he talking about in the strict sense, or in the broader sense? Do/would other genospecies of borrelia behave in the same way, or produce these same peptidoglycans?