Bioinformatics Methods in Identification Protein Function | Domains |Trans-membrane etc.,

In this video we used multiple computational prediction tools to perform various protein sequence annotations such as Physio-Chemical Properties, Identification Domains, Transmemrane Regions Prediction, Secondary Structural Elements, Solvent Accessibility Surface Area etc.,
Input: You need provide only Single Letter Amino acid sequence in FASTA format.
Sequence Retrieval Databases :
www.ncbi.nlm.nih.gov/protein/
www.ensembl.org/
www.genome.jp/kegg/genes.html
www.uniprot.org/
Protein Sequence Annotation Databases
1. Physico-Chemical Properties Prediction Tools
web.expasy.org/protparam/
www.tulane.edu/~biochem/WW/Pep...
2. Domain Prediction Tools
www.ebi.ac.uk/interpro/search/...
smart.embl-heidelberg.de/
pfam.xfam.org/
3. Trans-membrane Prediction Tools
www.cbs.dtu.dk/services/TMHMM/
embnet.vital-it.ch/software/T...
4. Secondary Structural Elements and Solvent Accessibility
www.cbs.dtu.dk/services/NetSurfP/
sable.cchmc.org/
5. Multiple Annotations Tools
www.predictprotein.org/home

[@sivask537]

Excellent... never though we can do so many things with protein sequence ..thank you sir great video ...

[@camila3843]

Thank you so much for this video! It helps me a lot!

[@amitgupta8736]

Thanks a lot...for a such knowledgfull lecture 🙏

[@agriculturelk2551]

Excellent tutorial. Thank you.

[@gutterball10]

Thanks for the lecture on these various tools. I found the transmembrane protein portion most useful. Just FYI: the Expasy data base transmembrane tool is going off line December 7 2021, according to the note left on that page.

[@ismaildin69]

sir you are amazing and I appreciate your hardwork and feel great and very nice information you have shared us by how using the protein sequence of the genes.

[@benysmart1643]

May ALLAH guide you to do the best..Thanks for sharing all this knowledge..very informative

[@pradeepupadhyay8184]

Great sir,,,,,

[@taofiqsanjid9641]

Thank you sir for this information

[@ahsanullahunar9767]

Thanks for sharing the knowledge.

[@jaannawaz2007]

Ur welcome...

[@garimanagar2549]

Very informative

[@eminegulceozel]

Thank you so much💐

[@soras2327]

Can you please make a video on phylogenetic tree building using Max LIKElihood approach on RaXml

[@sushantkumar-qg8rd]

Thank you so much sir giving a such knowledge

[@jaannawaz2007]

It's my pleasure

[@basu9316]

Liked ur videos sir...

[@jaannawaz2007]

Thanks

[@duafatima6283]

Hi, why did you predict the transmembrane region?what is it's importance?

[@tanushriroy5992]

Sir how can we find whether a protein is a glycoprotein or not?

[@agriculturelk2551]

Can you suggest me a sample research paper?

[@li2320]

have a one question..

[@kavitapatel8131]

hello sir, it will be a great help if you can show us how to make thousand peptide molecules and docked with any receptor, i am trying this from past 6 months and unable to do. i am trying to build peptide individually by openbabel (i have aa sequeneces, convert them in to fasta by putting sign > and the to pdb by open babel) and after making it is showing error during energy minimization.

[@h.upekkhaabhayarathne2274]

Is there any software to get few protein domain structures into one page nicely, in order to compare them easily

[@genomewidestudy]

Yes, You can get help from this video link
czcams.com/video/hYEiUYyhlZM/video.html

[@shikharani4973]

can we draw 3d structure of predicted protein which has not been submitted in NCBI

[@Martosway]

yes... by using swissmodeling

[@muhammadshahab1421]

Please make a vedio on QSAR

[@jaannawaz2007]

Sure... Coming soon

[@alansari1985]

10:15 he said "it is not gonna give you any ,,,, (what?)"