Jeff Lichtman: Connectomics: Mapping the Brain | Harvard Department of Physics

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  • čas přidán 19. 06. 2024
  • Despite intense interest in the ways brains work, we still have quite a rudimentary understanding of this organ, especially compared to our knowledge of the other organ systems in the body. One central problem is that brain function is based on a much more complicated cellular organization than found in any other part of the body. The brain contains billions of nerve cells and these are interconnected by trillions of synapses in a vast wiring diagram. This wiring diagram has not been described but likely contains the physical instantiations of all the brain does including all the memories we hold and all the skills we have learned. In addition such a wiring diagram may be disrupted when there are abnormalities in brain function such as learning disorders in children or psychiatric diseases in adults. In this lecture, Prof. Lichtman discusses how scientists are taking the first steps in imaging and understanding the wiring diagram of the brain.

Komentáře • 39

  • @JamieHumeCreative
    @JamieHumeCreative Před 2 lety +14

    This was fascinating. I really appreciate shared lectures from actual courses. I cannot afford to go back to school.Although I have an undergrad degree, which I did without full knowledge of my disabilities, of course, I didn't have the supports I needed. I am Dyslexic, have ADHD and am Autistic. I know I could have done more if I had understood what was happening in my brain that needed different approaches to excel consistently. My grades were up and down from fail to 4.0. So now, my joy is to flow through lectures at will as I find them stimulating and very interesting. I love knowledge as it connects with my interests. Now that I am officially diagnosed, I want to learn all I can about how the brain of ND people is different from NT people. I realize there is 'no such thing as average' which is even more intriguing. I would just love to audit in Neuroscience. But, unlikely to have that opportunity. AS a senior I might be able to score an opportunity in my area. I will look into it. Thank you. Please never stop making knowledge available It seems harder to do a search on these talks now as what comes up is just introductory classes.

  • @themotivationalmuseum
    @themotivationalmuseum Před 6 lety +25

    Thank you for sharing this lecture I love neuroscience. I began to study it on my own since I was young and now I finally decided at the age of 44 to study in the University.
    I've read so many books listen to so many lectures and even talked about it myself and seminars. I really love the function of the human brain. Thank you so much for sharing!

    • @24cf648
      @24cf648 Před 3 lety +2

      Can I ask you from where you started?

    • @leif1075
      @leif1075 Před rokem +1

      HOW can we make it easier..FUCK NO U don't want it to be harder as an adult

  • @Seomon1
    @Seomon1 Před 10 lety +8

    I really loved watching this, thank you Harvard, thank you Prof Lichtman and everyone else involved.

  • @anastassiya8526
    @anastassiya8526 Před 2 měsíci

    thank you, the lecturer's skills of storytelling are perfect. the lecture is fascinating and very memorable!

  • @anonviewerciv
    @anonviewerciv Před 3 lety +4

    Probably time for an updated version of this talk.

  • @MrSurferDoug
    @MrSurferDoug Před 10 lety +2

    Neurology still has a long way to go to understand mental illness and then treat. Hope this talk continues to inspire better understanding of the the brain and mind. It will be exciting to see what is learned in the next 20 years.

  • @KingOfThePanduz
    @KingOfThePanduz Před 5 lety

    absolutely FASCINATING

  • @naughteedesign
    @naughteedesign Před 10 lety

    toes amazeballs, love it! thanks for plopping this up for consumption

  • @josephbrady6760
    @josephbrady6760 Před 11 lety +1

    A very good lecture and v clear on a tough subject,,,great graphics....Joe

  • @jaydippatel8415
    @jaydippatel8415 Před 7 lety

    this is the very good lecture and thanks to put this video on u tube

  • @anniemoonmaid
    @anniemoonmaid Před 10 lety

    i realise my perception of my universe is through my brain, naturally i want to find out more about it...thank you for upload more fascinating revelations to come

  • @Neueregel
    @Neueregel Před 11 lety

    Great upload !!

  • @psychoctapus8069
    @psychoctapus8069 Před 3 lety +2

    This is an amazing lecture but I find myself having trouble with finding new data regarding these topics. He says that in as little as five years we'll be able to fully diagram a small mammalian brain, this lecture was posted in 2013, where could we find these diagrams, or updates on this type of research?

  • @cjstevens6405
    @cjstevens6405 Před 8 lety +1

    There is a longer, slightly more detailed 3 part version of the talk Jeff is giving here that is available over on the iBiology channel.

  • @kristinak2124
    @kristinak2124 Před 3 lety

    Love algorithm for this reason 👏👏👏

  • @NoMady688
    @NoMady688 Před rokem

    29:05 coordenação motora está ligado a todo exercicio que praticamos, pelo menos eu vejo dessa forma, ou seja mesmo que você não exercite um musculo sempre que faz algum movimento com essa parte do seu corpo o seu cerebro deve passar informações para outra parte do cérebro. E acho que apenas nesse caso existe o equilíbrio, entao sempre que você acorda e se levanta e se mantem em equilíbrio o seu cérebro deve de alguma forma acordar essas memorias antigas.

    • @NoMady688
      @NoMady688 Před rokem

      É assim que eu penso. Não quer dizer que eu esteja correto.

  • @victoriaghewlett
    @victoriaghewlett Před 9 lety +2

    damn that's some crazy shit

  • @leif1075
    @leif1075 Před 2 lety

    Is this a public lecture?

  • @wilburjames359
    @wilburjames359 Před 10 měsíci

    When did this happened?

  • @CarterColeisInfamous
    @CarterColeisInfamous Před 11 lety

    thats freaking crazy 0:39:00

  • @subramaniambrothers748

    EVEN WITH THE PRESENT SCANNER OF ONE BILLION PIXELS PER SEC , TO COMPLETE THE SCAN OF ENTIRE HUMAN BRAIN IT WOULD TAKE APPROX 72367 YEARS assuming the AVERAGE SIZE OF HUMAN BRAIN IS 1260 CUBIC CENTIMETERS.

  • @lightcity7963
    @lightcity7963 Před 6 lety

    motif is a key word, yet neuro-plasticity is not mentioned yet

  • @briseboy
    @briseboy Před měsícem

    Any question with which you disagree, yet consider important, is an excellent opportunity for you to advance from speculation nto formulating an hypothesis, an answerable question or many.
    Most questioned occurring to brains not having learned to bicycle (as analogy!) may be underdetermined - that is the question itself contains unexamined, unlearned errors.
    This, by the way, is the root cause of too many youtube comments; too many omissions and errors are contained in the brain of the commenter.
    Aggression does not replace either openness to novel stimuli, nor the most important impulse - to learn enough to even formulate the question or criticism into coherence, and thus usefulness.
    Literacy, numeracy, and perception of dynamical structural change are all higher-order concepts. Whether brain or object, nothing is static; to imagine anything at all as static on all scales is the fundamental error leading to sessile dogmatic stultification.
    Some scales are unimportant to us due to our lifespans. Entire new significant synaptic connections, though, can be generated within very few minutes.
    We learn best through eager focus upon real or imagined coherence/competence.
    Scientists present rationale for learning as ameliorating diseases. This is to gain funding.
    Optimality in complex dynamical systems differs from definitions of optimality in simple or static structure. The latter are largely imaginary.
    The term for rote-learned information has been called "fixed" intelligence. Crystallized intelligence is in contrast to fluid intelligence. This should indicate to you that the noun has two different, opposed meanings. Such conflation indicates that a vocabulary may contain cognitive errors; insufficiently defined terms or factors create concepts and brains struggling , like a failed bicyclist or drowning swimmer, in underdetermined situations - from THEIR point of view.
    Aggression does not resolve such cognitive difficulties, but does diminish any social interaction, and therefore, culture, community, function. Education is corrupted, when individuals or coalitions attempt to suppress openness to novel experience or research.
    Though my own interest and research is involved in basic questions rather than the ubiquitously popular applied questions appealing to psychosocial aberrations, this comment is an attempt to encourage questing in "what works" and adaptation rather than funded and focused upon nonadaptiveand maladaptive errors.

  • @AlphaNumeric123
    @AlphaNumeric123 Před 10 lety

    0:56:31 3D visualization (hand segmentation) 0:38:36 Brainbow glory

  • @slovakmath
    @slovakmath Před 10 lety

    the 1st person who tells me the VERY basic elementary error he made somewhere between 15:30 - 16:30 will get a reward from me! Don't worry its not hard, try to see his mistake

  • @ibrahim-ri4yj
    @ibrahim-ri4yj Před 2 měsíci

    ما جدوى ان تعجت و اندهشت ان لم تجد الجواب المصيري لوجودك و حياتك و هو ماذا تفعل في هذا الوجود ان لم تستطع معرفة و ادراك خالقك . هل ستنتظر ان تحصي عدد الخلايا العصبية الى ما نهاية ؟ انا دخلت لارى هذا الفيديو لا تعرف على خالقي . و هذا قربني فعلا الى خالقي و جعلني اعطي معنى لحياتي . و لم اعد خائف من المستقبل و ما يحصل معي . لا تنتظر ان ترى خالقك بالعين المجردة و يكون غباء منك . و لكن فقط من خلال نفسك تعرف على خالقك . و شيء طبيعي لا حظ للصدفة امام روعة ما نسمع في هذا الفيديو من معلومات . اما ان خرجت من هذا الفيديو كما دخلت فاعلم انك لن تتغير .

  • @NetaAlkan
    @NetaAlkan Před měsícem

    You are not everyone, what an overstatement about adults, if you are static and can't learn anything that's your problem

  • @timtae9369
    @timtae9369 Před 2 lety

    this reminds me of derek shepherd
    .

  • @nicktheo1497
    @nicktheo1497 Před 10 lety

    hahaha

  • @leif1075
    @leif1075 Před rokem

    NO PLEASE HOW CAN WE MAKENIT AS EASY TO LEARN AS AN ADUKT AS ITNIS AS A CBILD..I need to learn how to ride a bike.why the fuck did I have trouble...indont want to have more trouble as an adult than as a child..

  • @NetaAlkan
    @NetaAlkan Před měsícem

    Bullshit, nonsense

  • @pizzapizza8017
    @pizzapizza8017 Před 5 lety

    this is italian jerry pull hack scream off u could see it va unqualified student life at Harvard eye exam Asian guy left eye make a medical appointment