Hemolytic Anemias- Part 2: SICKLE CELL ANEMIA- Pathology

Hemolytic Anemias- Part 2: SICKLE CELL ANEMIA- etiopathogenesis, clinical features, diagnosis & management
HEMOGLOBINOPATHIES
Clinical diseases that result from a genetically determined abnormality of the STRUCTURE or SYNTHESIS of the hemoglobin molecule.
The abnormality is associated with the globin chains
The heme portion of the molecule is normal.
SICKLE CELL DISEASE
Sickle cell disease is a multisystem disorder that is caused by a single gene mutation.
Group of disorders characterized by production of sickle hemoglobin ( defective hemoglobin) HbS
SICKLE CELL ANEMIA
Homozygous state caused by β-globin gene mutation.
Point mutation involving codon 6 of β-globin gene
This leads to the substitution of Valine residue for a glutamic acid residue resulting in sickle hemoglobin.
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Please feel free to post queries or comment on the video😊 Good luck.

[@pavanjadhav5116]

Tomorrow is my micro patho exam.And the only reason I am confident about it is you.Thank you for your efforts sir😍❤️

[@debigdogk9563]

Outstanding teaching, from a great teacher, thank you and thank you. Love from London ❤❤❤❤❤❤

[@ilovepathologyVijayPatho]

Thank you 😊🙏

[@gaddamnavya6114]

Thank you very much for creating these wonderful lectures 😍

[@ilovepathologyVijayPatho]

Thank you 😊 do share among your friends 😊

[@hiraafzal6208]

Simply outstanding explanation!

[@HariKrishna-jm6jv]

Best pathology videos on yt 🔥🔥

[@ilovepathologyVijayPatho]

Thank you 😊 do share among your friends 😊

[@Getrealpeeps]

Thank you for this info on Sickle Cell Anemia.

[@spoorthisrinivas.]

Cvs topics(MI, heart failure,rheumatic heart failure etc)

[@shivanimaggon]

Thank you for the clear & in-depth explanation of the topic sir!

[@tinashekapfunde1467]

Thank you for the great work 👏👏👏

[@prabalmajumder5179]

Sir your presentation is just awesome ..very informative ..thanks

[@shivanisaini641]

presentation is very good!!!!
thank you sir!!

[@DS-eq4si]

Sir, please make more videos , please. We PGs keep are immensely benefited by your videos. Please Sir🙏

[@mohammadrahis1999]

thank you sir..loved this

[@user-sl3pb2ef2l]

Thank you sirr for the clear explanation It helps so muchhhhhh Your explanation is much more clearer than my lecturer’s explanation 😍😍😍

[@m_m786]

Great ❤️👍💕

[@waelfadlallah8939]

Elaborate explanation sir thank you very much for the effort

[@prabalmajumder5179]

Sir your presentation is just awesome ..very informative thanks

[@Artsylove4]

Thank you so much sir 💖💖

[@VimalKumar-zx7hu]

Excellent teaching sir.....
Please, upload videos on other topics also.

[@briz5612]

Loved it! Thank you.

[@lukasshemuvalula8671]

Great video🙏🏿

[@DS-eq4si]

Sir, please make videos on lymph node pathology, including lymphomas, for PGs... a very kind request Sir🙏

[@babaindarhai]

Plz make video on histopathology sir

[@lisaoney1973]

Finally found a cure for my son Sickle cell I’m so glad you came into my life. I pray for long life so you can save more souls,Thanks #uromi

[@faiza1118]

U r gem 🤩

[@PranamyaNayak-et2dv]

Thank you Sir🙏

[@srinivasreddyvadicharla5887]

Absolutely brilliant 👍👍

[@003abinayam5]

awesome videos , which was u put in youtube sir , put more videos for us sir

[@somalmeraj6951]

kindly complete all the types of anemias

[@sunilbabas9628]

Superbb 🌟

[@furqanahmad4522]

Sir plz make videos on the remaining pathology ..

[@furqanahmad4522]

Sir plz cover other chapters of robins basic pathology as well ...😊

[@abinayamurali7655]

Sir please upload video on thalassemia

[@9841329418]

LOVED THE PRESENTATION, THE ABSOLUTE WAY TO TEACH SCD

[@mdnaeemislam5007]

thank u so much sir, very informative and so easily explained that any body can understand this precious lecture❤️❤️❤️

[@iqraislam4509]

plz make video on thalassemia

[@ishikahahaishika]

Thankyou ..

[@philip6003]

Lovelyyyyyyyy

[@soundaryam2339]

Please share notes

[@googlekay3914]

Guys can anyone tell me where to get pathology exam notes for university exam in PDF form

[@jnaneshyd]

❤

[@jagadeeshGanta1205]

Is it severe in 58 percent of hbs level in SCD patient?

[@bhushan05naitam]

Bring part 3,4.

[@kuruvimbbs3667]

🙏🙏🙏🙏

[@aniketgulati16]

How can I get your pdf

[@shabanakhan8342]

Thank you sir

[@devanshuranjan1956]

Plz provide lectures in hindi, if possible

[@shabanakhan8342]

Thank you sir