Effects of TEA Antioxidants on SARS-CoV-2 Pathogenesis
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- čas přidán 25. 06. 2024
- A Review and Discussion of My Favorite Tea Science Article from November 2021
00:00 - Changes to "This Month in Tea Science" since October 2021
01:00 - Introducing the Topic of 'Tea and SARS-CoV-2'
03:30 - Breaking down the title "Discovery of Camellia sinensis catechins as SARS-CoV-2 3CL protease inhibitors through molecular docking, intra and extra cellular assays"
04:55 - Explaining methodology (selected assays and tea catechins)
07:17 - Results of molecular docking
08:03 - Results of intracellular and extracellular assays
09:08 - Explaining IC50 value, dose-dependency, and bioavailability of tea catechins
11:50 - GCG surprisingly outperforms EGCG in 3CL protease inhibition
14:42 - Wrapping up and summarizing significant findings
15:41 - Implications for future drug development
16:35 - Reiterating the complex nature of this type of research
17:25 - Closing remarks
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Original research article located here:
doi.org/10.1016/j.phymed.2021...
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Credits:
Outro song by Jared Mulcahy
Turkey image in thumbnail: "Thanksgiving" by Don McCullough is licensed under CC BY-NC 2.0
I've been binge-watching this series and binge-learning. This is great, keep making 'em!
@TheYashie That's great to hear!! And it is all the motivation I need to keep 'em coming :D
It's been tricky to walk the line between science article and CZcams video, because you never know just how much detail to provide. My goal is just to take feedback and make each month's video a little better than the last.
P.S. Sorry the whole November video was out of focus !! (rookie mistake)
@@wumountaintea I would say this is perfect. You're the MUCH needed middle ground between scholarly article and laypeople who want to learn, but maybe aren't equipped with the tools to decode papers ourselves.
@@TheYashie Thank you so much for this positivity and encouragement! :)))
@@TheYashie I agree! Just found this series and have been binge watching myself! Sad it seems that the series has fallen off
@@tonyskinner871 He'll probs be back
very nice o cover this topic, i never heard it from westerners
Hey Dylan, once again your video brought a question to my head: Why tea? Out of hundreds of thousands of flowering plants, is tea really as singular as it seems to be in terms of health benefits or is it just because comparatively we know this plant so well? Has the world focused its attention on tea because of the caffeine, because we can coax so many flavors from it, both? Is this plant really so special or have we just not given other plants the same attention? I suspect the answer is not a simple one, but if you had some ideas, I love to hear them. Be well.
In my opinion there are a few things that make tea very unique from other plants. 1. It's caffeinated and gives you a buzz... people like psychoactive substances. 2. There is a much much higher concentration of polyphenols in tea leaves than almost any plant we know of. This mediates many of the health benefits and medicinal properties of tea. 3. L-theanine is a tea-specific amino acid with calming effects that synergize with the stimulatory effects of caffeine to create a very unique 'relaxed focus' mind state (in addition to providing general anti-stress effects). Those are the three biggies in my opinion. Also, on my channel I may give the impression that it's just tea alone that provides these great effects because I only focus on tea on this channel - that's just personally what I focus on... but in reality all of nature is one big medicine cabinet. Many many other plants have incredible healing properties besides tea. My goal is simply to make the most out of this one in particular 😊 Thanks for watching and commenting it means a lot to me 🙏🌱🍵
- Dylan
Clearly you have never been tea drunk. 🤣 Once you experience Cha Zui (tea drunk) you'll understand the obsession with tea. 😊
@@robertarnesen3632 Hey Robert, Although I'm not sure I've fully experienced being tea-drunk, I long ago fell into an obsession with tea. My question was trying to address just how unique and amazing a plant tea seems to be. I find it fascinating and worth pondering. In the meantime, I'll keep working on being tea-drunk.
@@robinredbeard While my previous comment was whimsical humor, on the serious side I find tea fascinating as well. While it may not be a panacea, what other plant has so many potent and noticeable health benefits in its raw form? I'm constantly reminded of the old Tibetan saying, "Better three days without food than a day without tea." As a beverage, food and medicine used for thousands of years it has earned its place as most consumed beverage in the world, second only to water, for good cause. I find it hard not to be fascinated by it.
@@robertarnesen3632 BTW, I had not heard the saying, "Better three days without food than a day without tea." Thanks for that.
Can tea increase or balance the ph level that could bring down the inflammation response?
Are there any studies on tea & inflammation?
Yes! Many many studies have found tea to have powerful anti-inflammatory properties - this article explores this effect a bit (linked below) Also Chapter 6 of the Masterclass posted last week reviews this science in detail (second link posted below) Let me know if you have any more questions about this topic!
- Dylan europepmc.org/article/nbk/nbk92768
czcams.com/video/n4YpGbSmaFE/video.html