Tetanus Toxin vs Botulinum Toxin | Comparisons Series

Tetanus Toxin vs Botulinum Toxin | Comparisons Playlist.
Clostridium tetani secretes Tetanospasmin which causes tetanus (spastic paralysis) by inhibiting the realease of GABA and Glycine neurotransmitters.
Clostridium botulinum secretes Botulinum Neurotoxin (BoNT) that causes botulism (flaccid paralysis) by inhibiting the release of Acetylcholine (A.Ch.) at the neuromuscular junction.
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Hi Medicosis!
Great comparison by the way

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[@williammuirhead6927]

Hey Medicosis,
I’m not going to medical school, but I just have a general interest. Would the respiratory paralysis from tetanus be spastic or flaccid? It seems like it would be spastic, but I didn’t want to rule out flaccid paralysis via depolarization block following the overstimulation.
Thank you!

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