Assay Techniques. Methods used in drug discovery

Lecture in the undergraduate module "Clinical Drug Development"
0:53 Types of assay
2:00 Ligand binding assay
5:52 Specific and nonspecific binding
11:28 Competition (displacement) assay
14:02 What does a binding assay detect?
14:50 Scintillation proximity assay
16:45 GTPgammaS binding assay
19:25 Bioassay
24:36 Assays to measure potency
29:01 Features of a good bioassay
30:53 Summary of assay applications

[@aaronboswell5]

This is a very useful overview the various types of ligand binding assays and cell-based bioassays used in clinical drug development. Thanks for sharing, Professor G.

[@ooiTzAmii]

Thank you for this. Was quite confused with specific and non-specific binding methods and calculations.

[@avikparekh4578]

Very nice presentation

[@ThePalmer23]

extremely useful! thank you

[@kyshark1]

Very useful. Thanks