Acute Pyogenic Bacterial Meningitis Part 4 🩺

#drnajeeb #medicaleducation #pharmacology
Acute Pyogenic Bacterial Meningitis Part 4 🩺
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▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬
00:00:00 Release of cytokines and their actions
00:03:34 Recap of steps of Pathogenesis of Acute Pyogenic Bacterial Meningitis
00:05:18 Damage to brain or meninges is more done by our immune response than bacteria
00:05:52 Changes to CSF and its pressure in acute pyogenic bacterial meningitis
00:12:06 Importance of checking intracranial pressure during lumber puncture in patients suffering from acute pyogenic meningitis
00:12:40 Some tests for diagnosis of Acute pyogenic meningitis
00:13:50 Recap of steps of Pathogenesis of Acute Pyogenic Bacterial Meningitis
00:14:27 Vasogenic edema and interstitial edema
00:21:15 Cytotoxic edema
00:24:07 Herniation and effect on 3rd cranial nerve due to Acute Pyogenic Bacterial Meningitis
00:28:07 Complications due to Acute Pyogenic Bacterial Meningitis
00:33:00 Summary of lecture
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Acute bacterial meningitis (ABM) is a disease with rapid onset, outbreak and epidemic potential, and high rates of mortality and morbidity [1,2]. Considerable advances have been made in the last 30 years towards epidemic management and disease control through vaccination, and understanding the contributions of both host and pathogen to clinical outcomes. In this review, we will summarise the rapidly changing epidemiology of ABM in the context of new vaccines. We will show how new unbiased genomics technologies are revealing specific host-pathogen interactions that cause inflammation and brain damage. Additionally, we will summarise which new adjunctive treatments are in development and describe how the current Severe Acute Respiratory Syndrome CoronaVirus2 (SARS-CoV2) pandemic may impact on the WHO's efforts to defeat meningitis by 2030.
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