A new superweapon in the fight against cancer | Paula Hammond
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- čas přidán 24. 08. 2024
- Cancer is a very clever, adaptable disease. To defeat it, says medical researcher and educator Paula Hammond, we need a new and powerful mode of attack. With her colleagues at MIT, Hammond engineered a nanoparticle one-hundredth the size of a human hair that can treat the most aggressive, drug-resistant cancers. Learn more about this molecular superweapon and join Hammond's quest to fight a disease that affects us all.
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My mother has the BRCA1 gene mutation. Due to this she has had cancer 7 times in the past 4 years. It started as ovarian cancer which was treated and she went into remission. It kept coming back even though she had an oophorectomy and hysterectomy. She also had both breasts removed because of the almost 95% chance of breast cancer she had. She has a colostomy bag because 2 of her tumors wrapped around her intestines. She's the strongest person I know. I think I've only heard her complain a few times about how the chemo feels over the past 4 years. I pray that they will find a complete cure for cancer to help her and everyone else in need.
I have prostate cancer and Dr. Hammond's dedication, her research, and brilliance have prolonged my life. As a twist of fate, and unknown to her, she is my second cousin; and has given me and others the gift of life. God bless her.
This is the true power of nano-technology.
Ted has been cleaning its act up recently, well done....dont make me regret this comment Ted.
+ablanchi Unsubscribe if you don't like it. They haven't cleaned up anything, they're going through their catalog.
+ablanchi her lecture was the opening act for a Kanye West poetry contest
*Look below for some well documented facts that should be glanced over - excuse the randomness lol*
*Broadcasting Stations:* Jewish individuals do in fact own majority broadcasting and media stations - Aviv Nevo, Sumner Redstone, Bob Iger, etc.
*Political Campaign Donors:* Jewish individuals are arguably the biggest U.S. political donors - Charles & David Koch, Michael Bloomberg, George Soros, and Sheldon Adelson.
*Lobby Groups:* AIPAC Jewish lobby - Known as one of the most powerful lobby in Washington, which openly admits bringing Jewish donors and politicians together for the campaign donations. *(The New Yorker - Friends of Israel)*
*Federal Reserve:* Jewish individuals have been in charge of the Federal Reserve - Janet Yellen, Ben Bernanke, Alan Greenspan
-Paul M. Warburg (Jewish Individual) played a major role in drafting the Federal Reserve Act, and he is described by the Fed as "one of the system's architect and staunchest proponents."
-The Federal Reserve is actually not federal but just a private bank which is operating unconstitutionally since it prints and lends money to our U.S. government in interest. According to the Constitution, only Congress can print our money and to do so for free. *(Article 1 Section 8 Clause 5 of the Constitution)*
*Banks:* Jewish individuals have been in fact in charge of top banks.
Former - Rothschild Banks, Jacob H. Schiff, Paul M. Warburg, Abraham Kuhn, August Belmont, etc.
Current - David Rockefeller, David Rene de Rothschild, Lloyd Blankfein, Gary D. Cohn, Jacob A. Frenkel, Ruth Porat, etc.
*(I provided you names so no excuses. I am also against discrimination of any kind)*
These are the kinds of videos that really makes TED shine. Great stuff!
+Beebs Muhgoo Also, love to listen to Paula speak. Her energy and confidence is very inspiring!
I loved how well she explained the purpose of each layer.
This is wonderful news. I'm sure many would have liked to have a link directly to a site with more information on this treatment. Many truly appreciate your work Paula!
Always hear about this amazing stuff and then nothing happens, so tired of it.
+Guy Gadbois i know right, i was thinking the same
+Guy Gadbois check video - david noakes and dr rima laibow on big pharma- this talk is about the supression of Gc maf ( easy cure ) inexpensive and available but now banned in 88 countries.
because it always stops with talk. no action by the people and when you think about it how many people are truly waking up in the morning and saying I am going to dedicate this day to fighting caner. the real thing to do is make that a habit for a lot of people
What an amazing person
Very interesting, but.... how much does it cost to produce? Is it even viable? How realistic is this? What are the downsides?
+Ling Earth While you, the MuricaMan, eats more garbage and spouts out more stupidity into the world!
Did you watch the video? It already worked. The only step left is to modify the gene blockers for different types of cancer cells.
+Kadulikan Successful animal tests doesn't directly translate into a promise of treatment.
+J.P. I agree. Stop testing on the animals, poor them. Just grow skin cells and infect those... it's even better since those are human. OK, you don't get the immune system but yeah :-( we need to advance our ways of testing.
Grow a heart in the lab, get some antibodies in there etc. and test on that...
Alexandru Gheorghe you live in a fucking fairy tale, aren't you?
incredible.. i like to find out more.. 6 years have passed.
... Sure, superheroes...
I guess curing cancer just isn't enough to get people interested these days.
*****
Sadly just one won't be very effective.
And when will this be available to the public for treatment?
+gnarlin
When they've figured out how many extra arms it causes you to grow as a side-effect.
awesome ... this really fills me with hope for the future generation ....
Simply, a brilliant woman, well done.
amazing stuff. great presenter.
Great talk, looking forward to seeing this applied world wide.
TED had been hitting it out of the park lately! So many great talks and great people, and many fewer business and product pitches!
thank you for giving hopes. thanks for an awesome speech.
Wow!!! She's just brilliant!!! 👏👏👏👏
my mom got a recommendation from a docter to consume a potreleum (kerosene), the doctor said his father can reduce the tumor cells cause consumed that potreleum. I wish this recommendation can work well in my mom too.
Amazing woman. So proud
Just a thought, would it be better to use siRNA targeting ribosomal RNA and degrade that to directly starve the cells of their protein synthesis ability and possibly kill cancer cells non-discriminately?
I have the same questions. This way seems very fancy though :D
At first glance I do not think so. Downregulation of genes by RNAi/siRNA is something that occurs upstream from the ribosomes. Besides rRNA usually isn't a cause of cancer itself, expression levels of ribosomal (sub)units are relatively stable in many tumors. That means that specifically targeting rRNA as a target for oncolysis might leave healthy cells susceptible to ribosome inhibition as well, because the siRNA is a non discriminate target of cell death. I think this would do more harm than good, but I haven't looked into it. Targeted therapy using siRNAs/miRNAs against mutated rRNA might actually work though, but that's very hard to do with current technology. That'd be a rad idea though.
has anyone looked up DR BJORN NORDSTROM and the book he wrote back in the 80s the title of his book is BIOLOGICALLY CLOSED ELECTRIC CIRCUITS, he treated all kinds of cancers with low volt electricity
that amazing if this is write it will save a lot of people bravo paula hammond
It sounds pretty nice but i have one question. Many people die while they get their chemo therapie. With this 'new' chemo, it sounds even more aggresive (because theorotical, the new weapon can get inside every cell better, not only tumor cells).
So my question: Can somebody withstand this kind of therapie?
+Zanxx Yami (Fresh D) Didn't she say that the negatively charged outer layer contained receptors for the cancer cells?
She's ripped, she takes that fight seriously
There is an article about this study? I work with nanoparticles and cancer research, but instead of molecular therapy, we use a drug (resveratrol).
I want to read this study. Very interesting
There are powerful people who don't want us to have a cure which saddens me because we would probably have it by now.
There are rich people that die from cancer so.. No there is no secret cure from cancer.
+Minferno13 He said powerful.. not rich...
+RedStingBlogs damn.. Rich=powerful, didn't you have noticed that m8 ?
Minferno13 Yeah no
No, they are doing their best to find the cure. Do you even realize how difficult this is?
Does anybody know if this tumor cell death would be necrotic or apoptotic? I'm just curious, because a necrotic tumor death in the brain could be a really big issue, due to the inflammation
amazing video!! very informative!!wish with this superweapon we can fight this supervillian
She's is amazing
impressive the things humans can do is unbelievable.
I don't believe you...
Nice, but when will any of these apparent breakthroughs make their way into human application? Is it an issue of cost and production? Are they held back due to regulatory constraint? Are they being extra cautious and slow to develop the therapies? Do they have problems transferring the benefits from rodent studies into human studies?
+Matthew Mitchell The rodent testing is pre-clinical trials, human clinical trials have three phases and take about 10- 15 years to gather sufficient data for the drug to go to market. Whilst this timeframe is long, it is done for our benefit!
+Matthew Mitchell it takes a lot of time and money to go through the approval processes for new drugs and treatments, ranging in years and decades.
***** What about terminally ill patients that need the drugs now? Why not risk death from an unproven drug, when the only alternative is certainty of death?
Matthew Mitchell Very sick patients can opt in to these trials, it depends on where the trials are taking place, what type of cancer they have and of course - whether the patient is competent to make decisions about their own healthcare. They are given a full informed risk assessment before agreeing.
If people can opt in, why are we not seeing breakthroughs happen then? And of-course earlier study results should be able to demonstrate if a treatment is highly effective even before approval, no?
Why do we hear so much about revolutionary treatments, but relatively little happens?
I would have loved to hear about the manufacturing side regarding these tiny pellets. Can RNA be mass produced such that spraying them to form a coat is viable?
+Tak Bernama Are you sure it's unfeasible? There are ways to commercially mass produce RNA. Unless I'm wrong, RNA polymerase is used to exponentially increase the replication of the RNA strand for commercial use
I never knew I wanted black Velma until now.
Literally LOLed at this comment
That is why science is very important
i use cannabis against cancer
Great News ;) Love it!
Jesus christ she defo hits the gym everyday
+Klypt Fa yup, she just only discovered (potentially) the cure to cancer, but sure let's comment on her less than ideal body.
Hey cool!! Any research about Cancer is always welcome!! :D Anyway I've some doubts; how you know that after destroying the gene, another one inactive related with the first one isn't methylated and can continue the machinery of cancer in that cell or neighbors??
Why not just use a substance that destroys the cell instead using RNA??
It could be more effective to use bacteriophages instead of a nanoparticle??
And could be possible apply a non-ionizing radiation to try to destroy the cellular protein machinery only in the acreages affected??
63 people love cancer
Keep it up!
Ok. pretty incredible. But how much does it cost to manufacture billions upon billion of these nanoparticles?
+Lunatic With A License A lot cheaper than it cost to do all the cancer treatments that often don't help much
1:16 Thats where your wrong kiddo
To quote Dawkins
Science works bitchez
Nature works.
my mother passed away in1971 from cancer my youngest brother in 1988 back then I felt like they would have a cure by now , now I'm wondering if they'll ever find a cure, what is this stuff ? what happened on this planet to cause this decease,
neat stuff
I wonder if the unusual diet I've followed for eleven years now might help cancer. For eleven years, I have lived more than 90% on fluid milk products, cow milk and cow cream. So every day more than 90% of my diet is some kind of milk--skim, 1%, 2%, whole--plus I sometimes buy pints of half-and-half or fluid whipping cream and drink them straight.
In my case the diet helps with an eye problem. To put it a little simply, if I eat solid, mixed food my eyes hurt and vision blurs; but if I follow the milk/cream diet, they feel and work okay.
I don't know all the reasons the milk/cream diet works, but I can explain one based on how my body feels. After you eat your food, the nutrients from the food go into your blood and circulate to the cells to nourish them. It seems to me that although my system does break up solid food it doesn't break it up as thoroughly as milk and cream, and hence when the nutrients from solid food reach the cells they clog and irritate the cells more than the nutrients from milk and cream, leading to pain and dysfunction. In my case the pain and dysfunction show up in my eyes, but I think for other people it might show up in other body areas and ways. I have the idea the milk/cream diet might therefore give relief to many diseases, including cancer, other eye disease, and fibromyalgia. I'm trying to get the medical establishment to test the idea, but that hasn't happened yet, so in the meantime I tell sick people about it thinking it might help them. So you might try the diet to see what it might do for you. It might not help at all, since I don't know of any fibromyalgic patient trying it. I tend to think it will help.
I got this idea from the Masai people of Kenya who live only on milk and beef from their cows. They do have one important rule for food mixing. They say "If a man eats meat and drinks milk on the same day, he is a glutton." So for me I must choose every day whether it will be a beef day or a milk day. I like beef, but prefer milk, so for me every day is a milk day. I really don't know what would happen if I had some beef days, but I've been quite content having them all be milk days.
the best way to fight cancer is with natural foods and supplements however once it reaches advance stage sof cancer it becomes more difficult as the saying goes an ounce of prevention is better then a pound of cure
What is that nanoparticle ? Is it available in the market ? Thats it
Wonderful: Battles. Super villains. Super weapons. Destroy.
Root cause resolution = PREVENTION. Great to have potential new curative tools.
How about also acknowledging & modifying the ENVIRONMENTAL factors that promote the conversion into mutant genes?
Book: Radical Remission by Dr Kelly Turner.
Those biceps tho...
I like her pecs
how about the tumour microenvironment e.g. macrophage that allows the cancer cells to stay alive even when we are able to silence the genes that cancer cells possess?
And about the Brazilian Phosphoethanolamine?
i don't understandt 2 things:
1) why only cancer cells absorb that drug, other cells don't identify that drug as nutrient?
2) if you can smuggle gene inhibitor into cancer cell, why you are killing it with chemo therapy afterwards, why not just inhibit gene that makes the cell uncontrollably multiply and leave it? or maybe repair it to the dna of cell that it mutated from
+lordicemaniac 1.) She said in the video that the polysaccharide layer has molecules that specifically bind to tumor cells. This way, non cancerous cells won't be affected.
2.) I don't think that's what she meant when she brought up this new method of killing cancerous cells. This new tiny pill is probably meant to avoid chemotherapy because of the harmful effects of it. The purpose of the tiny pill is to target a specific gene to stop the cancer from growing.
DNA in cancer cells are very much different than normal cells. If you look at karyotypes of cancer cells vs normal cells, you'll see the cancer cells have strange chromosome numbers. This means that multiple nondisjunctions happened during mitosis, and the cells aren't really "checked" to see if the chromosome numbers are correct. Because of this unchecked mitosis, cancer cells continue to divide uncontrollably, resulting in these strange chromosome numbers. I would imagine this is very difficult to repair.
+Cody Kalin We don't wait to repair them. As with chemo, we kill all of them good and bad, and we regenerate good, and try to kill as much as possible (that's why the negative effects as you pointed out). However, what we want to do at the end of the day is really target killing. You DO NOT want to repair those mutated cells, the body will just create new cells, so it's not that the problem. I hope they will succeed, this has been going for so many years.
Alexandru Gheorghe Yea, that's what I'm saying. I just gave reasons why it would be difficult to repair, if repairing was possible at all. I didn't mean to sound like repairing was a good option.
*****
Oh no, please do not understand me in the wrong way, I only tried to contribute to your argument.
Alexandru Gheorghe Ooh I see. Sorry I must've misunderstood you.
cancer is cancer.
Fantastic!
Whether inside or outside it is hi-tech war
Can you say were in the state
I always thought that the cure of cancer would be done with nanorobots.
I just told my brother the other day dude it would be cool if we could just inject people with tiny robots to help them fight cancer. I love this I hope it blows up
cool prezentation and probubly even technology. but you made prezentation that we need cure that will actualy work, fascinating but we know :D. Thou this is definetly huge improvement compared to videos vew weeks ago.
This woman just ooze smartness.
Were in the state r u
very good
Im sorry if this might sound stupid, but what about the discovery of cspr cass 9 last year that i heard also from ted that can modify genes? is it not applicable here ?
crspr cass 9 is a way to extract genes out of organisms, sort of a way to copy and paste DNA, while siRNA can block genes inside a cell.
SHE USED PREZI FOR HER PRESENTATION
Cancer Super Villain?
We don't need a cure for cancer, we need it legalising!!!
+Ian Evans Having said that, it would be preferable if government and big pharma stopped 'giving us cancer' in the first instance! Go check out 'nagalase' sheeple....
LOL
Yes I'm sure the millions of doctors and researchers around the World are collectively working together to give us Cancer. And I'm sure the millions of researchers are all keeping the cure from the public (Even though there'll never be a single cure since there are hundreds of different types of cancer which are very different from each other).
+BantPlased Yo They have already destroyed the ultimate cure for cancer you brainless idiot, that cure is vitamin D3, obviously you didn't check out the key word I gave you above, here's another "GcMAF". This is the level of idiocy I have had to contend with over the last 5 years of my research. For the idiot I am responding to, here is a LINK!!! therightofreply.blogspot.co.uk/search?q=nagalase#uds-search-results
+Ian Evans For all the other plum dumb idiots on the planet, if you feel you are not being murdered by the governments, the globalists and big pharma, check out some other key words....POLYSORBATE 80-THIMEROSAL-CADMIUM- STRONTIUM-ALCOHOL-ALUMINIUM-FORMALDEHYDE-FLUORIDE-SV40-NITRATES-ASPARTAME-RADIOTHERAPY-CHEMOTHERAPY-BOVINE FOETAL SERUM-BERYLLIUM-BISPHENOL A & S. Need any more fools? I have a list a mile long....
Good Job. Good Damn Job.
Its revolutionary... Is it wrong to get really excited over this?
+Ariaditya Pramestu yes because it seems every few months there is a new "revolutionary" thing to end cancer. Let's hope one actually works one of these days
+Michael Kerr
There are a lot of things that cure cancer because there are a lot of cancers out there. Saying you've cured cancer is like saying you've cured sickness.
well I have one question. How what if other harmful bacteria copy the technique of this superweapon, I mean the meathead how your superweapon gets trough the immune system
Does this use Anti PD-L1 and Anti PD-1 drugs?
What keeps this from entering non-cancerous cells?
Pac Oo EPR effect
It is a way of doing it. It is a nice way of doing it and who dosen't like nano? Although it is the wrong way to fight cancer.
+MrDami123
It works. So why would it be wrong?
Noah Williams It's a weapon against cancer not the solution to prevent it.
MrDami123
Why not both? Honestly though, cancer can be really hard to prevent. Especially considering how it can just happen randomly when the right mutation in a cell happens.
what does 'negatively charged' mean? Can someone explain it?
Unless I'm wrong, one or more of the non-metal atoms on the molecule are ionised to give them a negative charge, or it's a polar atom with negative polarity (non-metal)
macam mana nak buat?
so...a jawbreaker?
Could cannabis oil be considered to be a superweapon against cancerous cells in the human body ?Could cannabis oil be a less complex procedure and worth together with the human body's endocannabinoid system or is this sort of natural treatment not as viable as synthetically engineered solutions ?
+Coj0nes01 Weed doesn't actually cure cancer dude
DeoMachina How do you know?
Richard Wofford
All the weed smokers that still get cancer? Just a thought.
DeoMachina Cannabis oil, not smoking weed. And do you know personally weed smokers that have cancer?
Richard Wofford Oh my mistake, it's the oil that doesn't cure cancer too.
And no, since they died.
Hello i am watching your vido want to keep looking on your vido my daugather have brest cancer
There is no profit in a cure.
+Alex Ownz "Nobody has ever bought something that cured anything, ever"
Yawn. Sure.
To many dollars made for a cure. $$
So what does this mean? There is a cure?
We dont need all these we have the best protocoll from doctor Nicolla Gobzales in the world.
the super heroes 's reference were cringy. But good talk overall
what about cbd oil?
This was already cured. It's called a plant based diet. Gerson therapy.
+schmassbinder Herbivores still get cancer dude
Not peddling a political or social agenda? Refreshing
Well guess what, we’re losing.
or just go vegan
So any news in 2017';
💕
Or you could've have spent your time promoting a vegan diet, which is 70 times more effective at preventing cancer than a standard american diet, instead of spending all your money researching something to cure cancer.
+Fouupdy O'B You and your vegan bullshit
Friend, both of my grandparents died from cancer(skin and brain in my grandmother, lung in my grandfather.) They both tried vegan, all natural diets because they didnt want to try chemo. it works for a little bit, but the cancer adapts and still killed them both, when chemo and medication would have saved them. Please dont push something that doesnt work. its a short term helper, but diet change isnt a cure.
Watch "Uprooting the leading causes of death" on youtube if you don't believe me.
Sorry for your loss man, truly. But I never said a vegan diet cures cancer if you have it already. I only said or what I meant to say was it prevents you from getting it in the first place.
1 2 3 you could have just posted the link.
I bet she doesn't listen to rap music.
Wow
rediculous
How about healing it with something called positive energy? *Everyone* should watch a video called _Powers Of The Mind! (What we all can actually do!)_. Just search it on CZcams and tell me, what you think about it.
+PsychoHaremDave A lot of people have died because they chose prayer over medicine.
this doesn't seem like something that would be relevant to the public market. production cost along with difficulty of development make it improbable to be used on anyone but the most well insured or wealthy patients. I have stage 4 lung cancer and a developing brain tumor and to be honest this doesn't give me much hope. I believe there will be a cure in the future but I will not live to see it.
+ibmason1 Theres always a way
+ibmason1
What makes you so sure that it's expensive?
think about the time and complexity of making something like that.
ibmason1 Think about how the complexity of making computers and tablets. Isn't that 10 times this?
the scale alone makes it more complex as far as I know. in any case my one opinion means nothing anyway.
While I think the idea is really interesting, there wasn't very much to this video. Basically all of the detail she offered was metaphorical. There wasn't any information about how it compares to current treatment options with respect to cost or effectiveness or side effects, or indeed any information at all which would be useful to know about it except that it exists.
Curing cancer is an awesome goal, but the concept behind TED talks is "Ideas worth spreading", not "here have some hope". There were no actual ideas in this video. If you have proprietary secret technology that you need funding for, trying to give a TED talks presentation to get it seems disingenuous and cynical, and honestly that seems like my biggest impression on what this video - and many of these videos - were for.
+carrionpigeons
Really? I saw it as more of a presentation of an awesome new thing she came up with. She was telling us what it is, not just that it exists.
+carrionpigeons she presents from the same perspective that Uber CEO presented... He talked about the driver-less future. That's an idea worth spreading.
She is talking about leveraging nanotechnology for drug delivery. That's an idea worth spreading. People think of cancer as if it's one disease (they see it like the slide at 0:40). But it's the slide at 0:55 that keeps folks scratching their heads, often over problems like drug toxicity...medication works, except it works in too many places throughout the body. So, nanotechnology is the future. We just need more people thinking about it. Sounds like an idea worth spreading.
Nerf miner
Is This is a startup pharmaceutical company looking for money? Best is not to get cancer in the first place. Diet makes a big difference via a whole food plant based starchy diet that is low protein low fat.