Unleashing the T-cell army | Cancer immunotherapy at Roche

Cancer immunotherapy helps us enhance our immune systems so that they’re able to fight cancer, enabling our bodies’ T-cell armies to attack the tumour microenvironment. In support of our immunotherapy efforts, Roche’s research and development team managed to separate the 200+ known cancer types into 3 primary immune profiles: inflamed tumours, immune excluded tumours and immune deserts. Understanding these profiles helps us develop different treatment strategies that allow us to target each individual’s immune biology.
The cancer immunity cycle is a framework that helps to explain how tumours interact with the human immune system. Listen as Roche Global Head of Cancer Immunotherapy Dan Chen and Vice President of Cancer Immunology Ira Mellman provide simple explanations of immunotherapy and the cancer immunity cycle.
To learn more about Roche’s commitment to cancer immunotherapy, visit www.roche.com/cancer-immunothe....
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[@DoubleGauss]

Great video !

[@gagegomez1]

I love this animation

[@zakiabelaid-choucair4044]

Yes Great video but the reality is more complex than this. it depends on the origin of the tumor (colon, lung, or breast), its phenotype and its interaction with the microenvironment independently of PD-L1 or PD-L2 expression or not. There is a major molecular mechanism shared by immune and non- immune cells that should be on the tumor cells leading cancer cells to cross a barrier and which expression is low or absent.

[@DoubleGauss]

I have many questions but i need a proper keyboard..cant type from my phone

[@roche]

@Lois Williams ECLIA stands for Electrochemiluminescence Immunoasassays.
Electrochemiluminescence is a detection technology for immunoassays. Immunoassays enable measurements of low concentrations of, for example, hormones in human blood.

In order to measure concentration of a substance, such as hormones in human blood, you can let it react with a specific antibody that is attached to a labeling substance. These can be chemiluminescent or electrochemiluminescent compounds. Electrochemiluminescence is a chemiluminescent process and it occurs with molecules including compounds of ruthenium, osmium or rhenium.