What are turbo cancers? Part 1: IgG4 effect on immune cells (update 136)

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  • čas přidán 4. 04. 2024
  • This is the first installment of a series dedicated to the molecular biology of unusual types of cancers called hyperprogressive disease that are colloquially referred to as “turbo cancers” (not a term used in medicine). In this episode, we provide the first ever published evidence of how IgG4 antibodies can play a role (in conjunction with other molecular events) in the development of turbo cancers.
    What we cover:
    *Turbo cancers exist in medicine but are called hyperprogressive disease
    *Turbo cancers appear to require 3 elements in the same environment:
    *cancer presence,
    *high IgG4 levels and
    *high glutathione levels
    *IgG4 immune checkpoint inhibitors used in cancer treatment
    *Hyperprogressive disease (turbo cancers) first described after the use of immune checkpoint inhibitors that were IgG4
    *Molecular understanding of how it happens only emerged in the last 5 years
    *Turbo cancers are still emerging knowledge as only a handful science papers published
    *2019 study of turbo cancer patients shows unique immune cell behaviour in cancers
    *2019 study of turbo cancers in mice provide genetic background predisposition
    Location: Calgary, Alberta
    Described content:
    aacrjournals.org/clincancerre...
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Komentáře • 1,2K

  • @Poisonedblade

    I have 3000 neighbors and a massive group of friends, family, and co-workers.

  • @pat24t
    @pat24t  +108

    Professor Angus Dalgleish, oncology specialist at St George’s Hospital London has said he was seeing patients who were in remission for years coming back with symptoms again. He said after the booster he noticed it more

  • @LorettaLaz

    My mother begged for Drs

  • @orbsandshadows8899

    I was a very healthy 42 y/o female. I got the forced vaccine twice in 2021. My health has been in rapid decline.

  • @puddspudds5102

    My dad . I will never stop telling people

  • @jdholbrook33

    I'll tell you what turbo cancers are.

  • @run4cmt
    @run4cmt  +164

    The 28-year-old step son of a friend died two weeks ago of a rare lung cancer. He was in the Army reserves and otherwise healthy. The cancer also moved very fast. He was a runner and never smoked.

  • @budhill7792

    A friend of me was diagnosed on Monday and died on Friday. Cancer in liver, head and stomach. I visited him last christmas where he was fine.

  • @mariecurie7491

    My ex husband, after 5 jabs (and 3 x lurgy), is a shadow of his former self. Has just been told he has a lymphoma. And a blood clot in one leg. Aaaand renal insufficiency with oedema. And I still recall the time in 2021 when he called and asked, aggressively, whether it was true that I had refused the vaccine

  • @angiehornshaw3680

    My Mom 74, had right breast cancer 30 years ago, then a tumor at the top of her right leg 5 years ago. She was clean and clear, cancer markers still clean August 2022. She started having pains in her right back in June 2023. Had an MRI and they found cancer in her right lung AND her spleen (left side). She was already in Stage 3. It spread so fast to her liver, kidney and had such serious fluid build up around her lung, that they couldn't get a grip on her pain but wouldn't drain it. They gave her until Feb. 2024, moved her to hospice. She didnt make it to Christmas. She had 5 jabs, going to her grave saying it would save her life. She had covid in hospice and passed away 2 weeks later. This was in Calgary. Still in shock.

  • @comment3711

    Thank you for covering this. We are losing a dear loved one to colon cancer. It spread to the liver and lungs before they even found out. They got the ‘stuff’ and they were truly the best of us in character, intelligence, kindness and what they have to offer the world. It’s a tragedy that keeps being repeated.

  • @Sn0wShepherd

    My wife's mother died from Hyper-Progressive cancer. My wife died at age 52 after uterine cancer caused an abscess that then caused recurrent sepsis. December 6, 2022, we were together over 20 years, and I am NOT even slightly finding muse of life without her.

  • @MickKly-ih4it

    Igg4 antibodies being produced in copious amounts in people who had 4 or more shots is the big elephant in the room .

  • @crittermetimbers

    Every single family member I have that was jabbed except 1 (so far) has had adverse effects.

  • @TNgrandee3

    My husband began not feeling well in May 2023. He was tested for Covid several times and it was always negative. From May to July 2023, he was seen by four doctors. The last doctor had a CT scan done on 14 July 2023 which showed a lung cancer that had spread to his liver. He died on 22 July 2023. His death certificate read cause of death high grade neuroendocrine tumor. He had had five Covid vaccinations.

  • @cherylcampbell7495

    My chiropractor told me I have spinal stenosis. High cholesterol and high calcium too. I started stretching hands behind head also vitamin K2. Peptide, collagen with bovine powder in my coffee. I’m 75 and after 7 months I’m a new person. No jab/jabs of any kind for me. I’m a caregiver and watched the elderly drop and end up in the er after the jabs.

  • @slerickson01

    My healthy sister with 5 jabs all of a sudden developed late stage lymphoma. She has two months or so to live. My healthy, 3x jabbed neighbor all of a sudden developed a spinal inflammation and was unable to walk within 24 hours. She’s been paralyzed from the neck down for a year now.

  • @kimberlyshaw6655

    I am so impressed that you are able to walk and talk and recount so much beautiful detail of the research you have studied! No prompter or notes but the information flows wonderfully to explain concisely, in proper order and in a way that is easily understandable ! It shows your brilliance! Thank you for giving of your time, your knowledge and empathy so that we all can benefit. You are a rare gem!

  • @haddenindustries2922

    One of my best friends fully vaccinated and boosted was diagnosed with a rare and aggressive cancer in november. He's undergone treatment and doing well as of this moment and is almost at the end of his treatment. He's 38, super atletic and there was no prior history of any form of cancer. The number of brain aneurysms and turbo cancers I've seen in people in my neighbourhood is staggering. I pray for the best but have to prepare for the worst since I'm the only one from my family and friends that isn't vaccinated.

  • @teresakarr8328

    I'm fairly sure Turbo cancer exists and it may not be caused from any sources we have observed in recent years. I'm super upset my neighbor went from job to hospice. This life is nuts! I know too much about loss and I can keep it to myself. People don't want to know. Wow