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Pharmacology: Simplified! Lectures by Dr Vallish
India
Registrace 7. 06. 2021
Welcome to Pharmacology Simplified! The purpose of this channel is to simplify tricky concepts in Pharmacology through video lectures. Watch these videos to convert pharmacology from a 'boring volatile torture of a subject' to an 'extremely interesting subject'!
Anaphylaxis: Why NOT Norepinephrine?
In this short video we briefly review anaphylaxis, and examine why Noradrenaline is not useful for its management
zhlédnutí: 328
Video
Why Levodopa Should Not be used in Drug induced Parkinsonism?
zhlédnutí 2,2KPřed 2 lety
In this short video, I have explained why levodopa is ineffective in the management of Drug-induced Parkinsonism.
Antiplatelet Drugs: Basis for Classification
zhlédnutí 121Před 2 lety
In this short video I describe the basis for classification of antiplatelet drugs
Calcium Channel Blockers as Antianginal Drugs - 2
zhlédnutí 326Před 3 lety
This is the second part of the video describing the antianginal properties of calcium channel blockers; part 1 can be viewed here: czcams.com/video/DW0WqHc24gA/video.html Other related videos: 1. Overview of types of angina pectoris: czcams.com/video/prDCXO5BtNA/video.html 2. Nitrates as antianginal agents: czcams.com/video/C4W_d8ohPBs/video.html 3. Beta blockers: czcams.com/video/nKi4vBal2y0/v...
Calcium Channel Blockers as Antianginal Drugs - 1
zhlédnutí 748Před 3 lety
This is the first part of the video describing the antianginal properties of calcium channel blockers; part 2 can be viewed here: czcams.com/video/8dtwFvgSLTI/video.html Other related videos: 1. Overview of types of angina pectoris: czcams.com/video/prDCXO5BtNA/video.html 2. Nitrates as antianginal agents: czcams.com/video/C4W_d8ohPBs/video.html 3. Beta blockers: czcams.com/video/nKi4vBal2y0/vi...
Nitrates as Antianginal Drugs
zhlédnutí 352Před 3 lety
In this video I have briefly described the pharmacology of Nitrates when used as antianginal drugs. Related videos: Overview of Angina (types, pathophysiology, management principles): czcams.com/video/prDCXO5BtNA/video.html Beta blockers part 1: czcams.com/video/nKi4vBal2y0/video.html Beta blockers part 2: czcams.com/video/QPq77QnxLIw/video.html
Angina Pectoris: types, pathophysiology, and management principles
zhlédnutí 214Před 3 lety
In this short video I have briefly described the pathophysiology, types, and principles behind management of Angina pectoris. Related videos: Nitrates as antianginal drugs: czcams.com/video/C4W_d8ohPBs/video.html Beta blockers part 1: czcams.com/video/nKi4vBal2y0/video.html Beta blockers part 2: czcams.com/video/QPq77QnxLIw/video.html
Pharmacology of Beta Blockers - 1
zhlédnutí 253Před 3 lety
In this video I have described the pharmacology of beta blockers, with propranolol as the prototype. This is part 1 of the video; part 2 : czcams.com/video/QPq77QnxLIw/video.html Part 1: Introduction, Classification, Mechanism of action, Cardiovascular actions Part 2: Other pharmacological actions, ADRs, Contraindications, Uses Also check out: Pharmacology of cardioselective beta blockers: czca...
Pharmacology of Beta Blockers - 2
zhlédnutí 123Před 3 lety
In this video I have described the pharmacology of beta blockers, with propranolol as the prototype. This is part 2 of the video; part 1 : czcams.com/video/nKi4vBal2y0/video.html Part 1: Introduction, Classification, Mechanism of action, Cardiovascular actions Part 2: Other pharmacological actions, ADRs, Contraindications, Uses Also check out: Pharmacology of cardioselective beta blockers: czca...
Cardioselective beta blockers
zhlédnutí 470Před 3 lety
In this short video I have described the background, advantages, and disadvantages of cardioselectivity among beta blockers. For other special properties of beta blockers, please see czcams.com/video/GkfagLIaIpY/video.html
Four special properties of beta blockers
zhlédnutí 311Před 3 lety
In this short video I have briefly explained the 4 special properties of beta blockers: cardioselectivity, lipid insolubility, membrane stabilizing activity, and intrinsic sympathomimetic activity. For a more detailed description of cardioselective beta blockers please visit czcams.com/video/Jcy4AqsKe1E/video.html.
Pharmacology of Adrenaline 1
zhlédnutí 3,8KPřed 3 lety
In this video I describe the pharmacology of Adrenaline under various headings. This is part 1 of the video on the pharmacology of Adrenaline. For part 2, please see czcams.com/video/uz7vTe3zY-8/video.html.
Pharmacology of Adrenaline 2
zhlédnutí 1,1KPřed 3 lety
In this video I describe the pharmacology of Adrenaline under various headings. This is part 2 of the video on the pharmacology of Adrenaline. For part 1, please see czcams.com/video/SNfnnWcuxKs/video.html.
Active vs Passive Mydriasis
zhlédnutí 1,7KPřed 3 lety
In this short video I talk about pharmacology of active and passive myrdiasis and the clinical significance of them.
Cholinesterase and its inhibitors
zhlédnutí 872Před 3 lety
In this short video I have explained about how cholinesterase enzyme works, and spoken briefly about cholinesterase inhibitors.
Organophosphate Compound Poisoning and its Management
zhlédnutí 924Před 3 lety
Organophosphate Compound Poisoning and its Management
Extremely helpful. Thank you
Are Parkinson's disease and DIP both same?
Superb sir
Nice explanation..Thank you
Thank you sir 🙏 now only I understood this concept . Please make more videos sir .
Excellent video sir ❤
Thank you doctor, it's an invaluable presentation, I have the DIP. I wish every neurologist, particularly those focused on Parkinsonism should watch it!
Thank u sir
I am happy that the video helped!
❤
But sir reserpine is dopamine depleter so dopamine levels will be decreased , then why cant we use levodopa there?
You are correct; dopamine depletors such as reserpine and tetrabenazine have a different mechanism of inducing parkinsonism that does not involve D2 receptor blockade, and hence levodopa can be used to manage this, along with replacement of reserpine with a safer alternative. Thank you for pointing this out!
@@pharmacology.simplified thank u sir
Can sodium valproate cause drig induced parkinson ?
Parkinsonism is a rare ADR with sodium valproate; check this publication: www.ncbi.nlm.nih.gov/pmc/articles/PMC7381881/
Sir i really liked your videos , they are very conceptual and i appreciate your effort 🙏. It is a request It will be very helpful if you post more videos.
mast padaya aapne thankyou 🎊💥
It was wonderful and really helpful for me. Thank you much, Sir. With warm respect, from Afghanistan.
Nice explanation Thanku so much sir
Thanks for the video. Very conceptual and informative. Really cleared my doubts on the topic🙏❣️
Crystal clear concept thankew sir
I was on escitalopram and went from 10mg to 5mg and developed jaw tremor (very minor) and hand tremor. I am now very slowly tapering off the medication. Even though the jaw tremor is not noticiable should I do something about it? It's not going away.
Thank you for the comment. I believe you should consult your physician or neurologist: if the jaw tremor is bothering your daily activities, it is advisable to have it thoroughly investigated. I hope you agree with me that giving medical advise without actual physical examination is not advisable for either of us.
if they ask for 4mark question how to write
Most important headings for any drug are calssification, MoA, actions, uses, and ADRs: learn these as a minimum, and other headings (PK, dosage forms, dose, special points, history etc) can be kept as less important. 4 marks, usually the question will be specific: they will ask a particular aspect of CCBs.
Why nor adrenaline is not used in anaphylactic shock treatment
One of the main objectives of anaphylaxis treatment is to reverse bronchoconstriction due to histamine. Bronchial adrenergic receptors are beta2, and noradrenaline doesn't activate beta2 receptors, and hence can't relieve bronchospasm.
@@pharmacology.simplified thank you sir
czcams.com/video/Yrg5UxFfw1A/video.html I just made a video to explain this in more detail.
Can escitalopram block the D2 receptors.
Escitalopram is an SSRI: selective serotionin reuptake inhibitor. It blocks SERT transporter: that is its main MoA. Its action on D2 receptor is minor, not clinically significant, and may (if at all) contribute to some ADRs.
@@pharmacology.simplified my wife was in depression and anxiety, ans she was prescribed escitalopram , she took it almost two years, but she developed several side effects when the drug was tapered she starts developing parkinson type disease, as the drug was tapered she developed more these sort of symptoms, is her symptoms are drug induced or parkinson disease.plz suggest, her neurologist has started synodopa 110 mg .
Unfortunately I cannot provide medical advice here, but if PD developed after stopping the medicine then the chances that it is DIP is low: usually DIP resolves after withdrawing the offending drug. You must consult your neurologist for best advice and course of action.
@@pharmacology.simplified ok thank you sir.
She has only problem of freezing or sticking of legs,this kind of symptoms developed while taking the drug, but each step on tapering the drug the symptom intensified, she has no shaking of hands , only legs numbness or senseless while sitting.
Helpful!
Clear , crisp , conceptual and short
Thank you, glad the video helped you!
Thank you !
Thank you, glad the video helped you!
Indications of diltiazem
Diltiazem indications: 1. Frontline: management of hypertension, vasospastic angina, supraventricular tachyarrhythmias 2. Second line drug: management of chronic stable angina (1st: beta blockers), 3. Other uses: component of treatment for unstable angina; also in acute MI and hyperthyroidism management when beta blockers cannot be used
Thankuuu
Glad that the video was of help to you!
Thank you sir....as super as your classroom classes..miss you sir
Thank you, glad you liked the video :-)