Video

Content: 0:08 4-in-1: Measure hardness, thickness, diameter/length and width of a tablet 0:12 Measurement of various shapes of tablets is possible 0:23 Width: Measuring the width of a tablet is the latest added feature to the PTB 311E 0:38 “4-in-1” Thickness Measurement 0:46 “4-in-1” Width Measurement 0:53 “4-in-1” Diameter or Length Measurement 1:00 “4-in-1” Hardness Testing 1:30 Password Protected Settings: Important settings like date and time are protected by a user definable password 1:42 Stay connected: The instrument is compatible with PT-Node 1:47 PT-Node is an instrument network adapter for printing and data transfer 1:51 Print reports via browser on any printer 1:55 Export results in your local network 1:59 PT-Node connects up to two instruments simultaneously with your network

0:23 AGENDA: 01:00 1. About us // Über uns 01:39 2. Dissolution validation // Wirkstofffreisetzungs-Validierung 01:45 a) Dissolution testers: Typical applications // Wirkstofffreisetzung Prüfgeräte: Typische Anwendungen 03:43 b) Global regulatory requirements for the validation of dissolution systems // Weltweite regulatorische Anforderungen an die Validierung von Wirkstofffreisetzungstestern 08:28 c) Critical control points // Kritische Kontrollpunkte 09:35 3. Calibration in practice // Kalibrierung in der Praxis 09:38 a) Mechanical calibration // Mechanische Kalibrierung 15:06 b) Chemical calibration // Chemische Kalibrierung 20:57 4. A global perspective // Eine globale Perspektive 21:05 a) What recent changes have you observed in your local pharmaceutical industries? 23:19 b) How do you see the development of the generics market and how does it impact dissolution testing? 25:13 c) What are some actual industry trends and how does this concern the need for validation? 26:34 d) How do you meet the requirements of such a diverse user base? 28:34 e) What are your experiences about Mechanical and Chemical Calibration and what challenges do you face? 30:45 Closing words

Our invention made it to the market :)

how external magnetic stirrer is powered?

CONTENT: - 00:16 Edit the method using the instruments keypad - 00:33 Safety switches prevent starting the instrument in case the racks are not inserted correctly - 00:44 The samples are withdrawn from the dissolution bath and collected into the vials inside the DSR-M collection rack - 01:13 The sampled volume is automatically replaced into the dissolution vessels; a dedicated pump fills the replacement media container (optional) - 01:22 The collected samples can be transferred into the second rack to perform a dilution step (optional) - 01:34 The universal racks can be converted to be used with HPLC vials instead of open vials with a few simple steps - 01:47 The individual needle can pierce cross slit closed vials - 02:10 DSR-M includes an integrated report printer - 02:21 The CAT-M piston pump module is fully integrated into the DSR-M housing - 02:28 The MFC-12 manual filter changer is used to add filtration to the sampling process (optional) - 02:35 Standard round filter suitable for HPLC analysis can be inserted and removed easily - 02:57 The collection area of the DSR-M is easily accessible to take out the racks or to clean the instrument

CONTENT: - 00:09 Select the unit of measurement - 00:19 Rotate the knob to move the jaw and apply force to the sample - 00:27 The break is automatically defected and the hardness value is immediately displayed - 00:34 Clean the testing area for the next sample - 00:39 Units can be switched even after the result has been determined - 00:46 Test odd shaped (oblong) samples without any additional tools - 00:59 Connect the PT-RP80 report printer for automated result reporting (optional) - 01:35 The report includes the actual results and statistics as well as date & time - 01:44 The instrument is powered by a 9V re-chargeable battery - 02:07 Alternatively a power adapter may be used as well - 02:16 To calibrate the force sensor, remove the test platform and knob - 02:23 Turn the instrument onto its side and place the calibration plate onto the stationary jaw - 02:33 Switch PTB-M into the calibration mode - 02:43 Carefully place the weight onto the calibration plate

CONTENT: - 0:10 Composed of: PTWS 820D dissolution bath, PT-SP8 high precision syringe pump and PTFC-2/8 SP fraction collector - 0:23 Large color, touch screen to control the instrument - 00:37 Visual signals on the display inform the user of the status of critical instruments parameters - 00:47 For manual sampling staggered stirrer start is possible - 00:56 Optional TM-820 tablet magazine for synchronous drop of all samples - 01:14 The TM- 820 tablet magazine is supported by flexible strings to avoid any risk of blockage - 01:24 Optional EPE-820 sampling system automatically lowers and raises the sampling probes - 01:34 Attached to the EPE-820, the ITM-820 temperature monitoring system reads and reports the media temperature inside the individual vessels during sampling - 01:44 PT-SP multi-syringe pump: Designed for parallel sample withdrawal and dosage of media from a dissolution bath - 02:16 PTFC-2/8SP offers automated sampling of up to 20 cycles with 8 vials each. The collecting dish is easy to load and unload - 02:39 The magazine includes low evaporation vessel sealing covers and magnetic holders for the tube cleaning device - 02:52 DFC-820SP Offline Automated Tablet Dissolution System Alternative tablet dissolution baths with 6 stations: PTWS 120D and PTWS 120S - 03:00 PTWS 120D is a compact 6-station tablet dissolution bath - 03:14 Available in the PTWS 120S version with individual stirrer speed control for all 6 stations

CONTENT: - 00:08 PTG-S4 - Measure flow time, cone angle, flowability, cone density and cone volume - 00:15 Integrated Sartorius balance cell - 00:25 Advances user and method management system - 00:33 Multi-lingual menu - 00:42 Integrated clear view dust production hood - 00:56 PTG-ER stirrer included - 01:07 Measure the powder cone volume- powder -powder cone density - 01:45 Integrated thermos printer - 01:52 Measure the powder flow time of a pre-defined mass - 02:18 The clear view dust protection hood can easily be opened and removed for cleaning - 02:35 The PTG-S4 comes ready to use with pouring nozzles: Size 6,8,10, 15, 25mm - 02:45 Optional equipment to test smaller volumes: A 10 ml funnel, a smaller sample collecting dish, pouring nozzles from 4 to 10 mm diameter and a suitable stirring shaft are available

CONTENT: - 00:19 Quick menu navigation by using a large color LCD and a clickwheel - 00:28 Multi lingual menu - 00:39 Sophisticated user and method management system - 01:09 Integrated Sartorius analytical balance modul for individual sample weight and tablet feeder for up to 25 samples - 01:26 Automated positioning: Movable alignment jaws automatically position the samples - 01:46 Automated cleaning procedure included - 01:59 Automated alignment: The samples are automatically positioned... even oblong shapes! - 02:10 Touchless thickness measurement: A class 1 laser beam measures the sample thickness - 02:26 Broken samples drop into the removable waste container - 02:35 Optional customized alignment jaws

00:13 CONTENT/AGENDA: - 00:42 1. Introduction - 01:28 2. Challenges in Drug Release Testing of Nano- and Microformulations - 02:50 3. Development of the Dispersion Releaser (DR) - 06:31 4. Design and Setup - 07:50 5. Manual Sample Operation - 08:26 6. Offline Sampling Procedures - 09:19 7. Online Measurements - 10:40 8. Advantages - 11:34 9. Other Applications (Outlook)

Content: - PTF 200 Tablet Friability Test Instrument 00:07 - The PTF 200 is part of the PTF series - with one to six drums 00:10 - 100% USP, EP and JP compliant 00:17 - Option to adjust speed from 25 to 75 rpm 00:25 - Creating test methods is easy and fully guided 00:39 - Click wheel for quick menu navigation 00:45 - Dual operation mode: number of revolutions or rotation time 00:52 - Alternative tablet filling through the opening hole of the drums 01:27 - Automatic sample discharge at the end of a test 01:54 - Clear Plexiglas collectors with magnetic positioning 02:00 - Easy user management 02:15 - USB interface: Save test reports, install updates and different languages via USB flash drive 02:32 - Integrated printer optional for the PTF 200 02:41 - FURTHER OPTIONS 02:57 - 10-degree angle stand for heavier, larger or odd-shaped tablets 03:00 - Abrasion drums are also available 03:14

Content: - 00:17 For tapped and apparent density testing of powders, granules, pigments and similar products - 00:23 100% USP and EP compliant - 00:27 Different cylinder positions for different tapping heights according to USP (= 14 mm) and EP (= 3 mm) - 00:46 Click wheel for quick menu navigation - 00:51 Creating test methods is easy and fully guided - 01:54 Integrated Printer - 02:01 USB interface: Save test reports, install updates and different languages via USB flash drive - 02:08 Easy user management

00:08 Content/Agenda: 00:23 1. Introduction 01:27 2. About Tablet Hardness Testing 04:36 [Demo video] Four testing stations: 1. weight, 2. thickness, 3./4. diameter and hardness 05:31 [Application video] Handling of the WHT 4 with different tablet shapes 03:27 3. WHT 4 System Overview 07:25 4. The WHT32 Software 11:04 5. Advantages

Interesting presentation, it gives much more clear insight on how courusel and software works than any other sources :)

Nice technology

in Hindi languages please sie

About to install one in Novartis Neva :)

Great presentation!