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Pharmacology Insights
Malaysia
Registrace 8. 11. 2011
Short and simple educational pharmacology videos for everyone, especially students in the health sciences field.
Drugs can be used to treat and prevent a wide range of diseases, from chronic conditions such as diabetes and heart disease to acute illnesses such as infections and cancer. However, it is important to understand how drugs work and how to use them safely and effectively.
Thank you for watching!
DISCLAIMER:
The content seen in my videos and the comments are provided only for education purposes and are not intended to be a substitute for professional medical advice, diagnosis, or treatment.
Drugs can be used to treat and prevent a wide range of diseases, from chronic conditions such as diabetes and heart disease to acute illnesses such as infections and cancer. However, it is important to understand how drugs work and how to use them safely and effectively.
Thank you for watching!
DISCLAIMER:
The content seen in my videos and the comments are provided only for education purposes and are not intended to be a substitute for professional medical advice, diagnosis, or treatment.
Donanemab For Alzheimer’s: Mechanism of Action & Key Clinical Study Results Explained│ Pharmacology
Donanemab targets a key culprit in Alzheimer's disease: amyloid plaque, a harmful substance that builds up in the brain and disrupts cell function. This video dives into donanemab's mechanism of action and explores promising results from a recent clinical study. If approved, donanemab would become the second FDA-approved Alzheimer’s drug of its kind on the market, after lecanemab.
Disclaimer: This CZcams channel is not intended to provide diagnosis, treatment, or medical advice. The content provided in this video is for informational purposes only. This should not be considered as a substitute for advice from a healthcare professional. Please consult with a physician or other healthcare professional regarding any medical or health-related diagnosis or treatment options. The statements made about specific products are not to diagnose, treat, cure, or prevent disease.
References
1. Kumar A, Sidhu J, Lui F, Tsao JW. Alzheimer Disease. In: StatPearls. Treasure Island (FL): StatPearls Publishing; February 12, 2024.
2. www.alzint.org/about/dementia-facts-figures/dementia-statistics/#:~:text=Someone%20in%20the%20world%20develops,and%20139%20million%20in%202050.
3. Rashad A, Rasool A, Shaheryar M, et al. Donanemab for Alzheimer's Disease: A Systematic Review of Clinical Trials. Healthcare (Basel). 2022;11(1):32. Published 2022 Dec 22. doi:10.3390/healthcare11010032
4. Sims JR, Zimmer JA, Evans CD, et al. Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial. JAMA. 2023;330(6):512-527. doi:10.1001/jama.2023.13239
#AlzheimersTreatment #ClinicalTrial #NewDrug #Dementia #Neurology #BrainHealth #HopeForAlzheimers #MedEd
Disclaimer: This CZcams channel is not intended to provide diagnosis, treatment, or medical advice. The content provided in this video is for informational purposes only. This should not be considered as a substitute for advice from a healthcare professional. Please consult with a physician or other healthcare professional regarding any medical or health-related diagnosis or treatment options. The statements made about specific products are not to diagnose, treat, cure, or prevent disease.
References
1. Kumar A, Sidhu J, Lui F, Tsao JW. Alzheimer Disease. In: StatPearls. Treasure Island (FL): StatPearls Publishing; February 12, 2024.
2. www.alzint.org/about/dementia-facts-figures/dementia-statistics/#:~:text=Someone%20in%20the%20world%20develops,and%20139%20million%20in%202050.
3. Rashad A, Rasool A, Shaheryar M, et al. Donanemab for Alzheimer's Disease: A Systematic Review of Clinical Trials. Healthcare (Basel). 2022;11(1):32. Published 2022 Dec 22. doi:10.3390/healthcare11010032
4. Sims JR, Zimmer JA, Evans CD, et al. Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial. JAMA. 2023;330(6):512-527. doi:10.1001/jama.2023.13239
#AlzheimersTreatment #ClinicalTrial #NewDrug #Dementia #Neurology #BrainHealth #HopeForAlzheimers #MedEd
zhlédnutí: 34
Video
Zilucoplan Explained: How This New Drug Works for Myasthenia Gravis │ Pharmacology
zhlédnutí 98Před 14 dny
FDA approval of zilucoplan (ZILBRYSQ®) has been granted for the treatment of generalized myasthenia gravis in adult patients who are anti-acetylcholine receptor (AChR) antibody-positive. In this video, we'll delve into how it works and take a brief look at the clinical trial that led to its approval. Disclaimer: This CZcams channel is not intended to provide diagnosis, treatment, or medical adv...
Tarlatamab: Mechanism of Action and Clinical Success in Small Cell Lung Cancer │ Pharmacology
zhlédnutí 151Před měsícem
Discover the revolutionary new treatment for small cell lung cancer: tarlatamab. In this video, we delve into its mechanism of action as an innovative bispecific T-cell engager (BiTE). We also highlight the pivotal clinical trial that led to its FDA approval. Disclaimer: This CZcams channel is not intended to provide diagnosis, treatment, or medical advice. The content provided in this video is...
Duchenne Muscular Dystrophy (DMD) Hope: New Treatment - Givinostat Explained! │PHARMACOLOGY
zhlédnutí 359Před měsícem
In March 2024, the US FDA approved Italfarmaco's givinostat (Duvyzat) for Duchenne muscular dystrophy (DMD) patients aged six and older. In this video, we'll break down what Givinostat is, how it works, and the results of the clinical trial that has led to its approval. Disclaimer: This CZcams channel is not intended to provide diagnosis, treatment, or medical advice. The content provided in th...
Sotatercept Explained: New Hope in Treating Pulmonary Arterial Hypertension │PHARMACOLOGY
zhlédnutí 314Před měsícem
Pulmonary arterial hypertension (PAH) can be a debilitating disease. This video dives into sotatercept, a new treatment option approved by the US Food and Drug Administration (FDA) in March 2024. We'll explore how it works, clinical trial results, and what it means for the future of PAH management. Disclaimer: This CZcams channel is not intended to provide diagnosis, treatment, or medical advic...
FDA Approves First Drug for Non-Alcoholic Steatohepatitis (NASH): Resmetirom Explained │PHARMACOLOGY
zhlédnutí 352Před měsícem
This video looks into resmetirom, a new treatment for non-alcoholic steatohepatitis. Discover how resmetirom is revolutionizing the management of this chronic liver disease and offering hope to millions worldwide. We'll explore how it works and the latest clinical trial results. Disclaimer: This CZcams channel is not intended to provide diagnosis, treatment, or medical advice. The content provi...
Tezepelumab for Severe Asthma: Mechanism of Action & Clinical Triumphs │ PHARMACOLOGY
zhlédnutí 126Před 2 měsíci
Dive into the world of tezepelumab, a revolutionary drug transforming asthma management. This video discusses its mechanism of action, explaining how it targets and neutralizes the root causes of severe asthma. We also briefly discuss the pivotal clinical trials that paved the way for tezepelumab's approval. Disclaimer: This CZcams channel is not intended to provide diagnosis, treatment, or med...
Zuranolone: A Game-Changer for Postpartum Depression Treatment │PHARMACOLOGY
zhlédnutí 104Před 2 měsíci
In this video, we delve into the groundbreaking medication zuranolone and its revolutionary impact on treating postpartum depression (PPD). Zuranolone is a fast-acting neuroactive steroid that targets the brain's GABA receptors, offering rapid relief from PPD symptoms. Join us as we explore the science behind how it works, its efficacy in clinical trials, and how it differs from traditional ant...
Elacestrant: A New Weapon Against Advanced Estrogen Receptor-Positive Breast Cancer
zhlédnutí 92Před 2 měsíci
Elacestrant belongs to a class of medications called selective estrogen receptor degraders (SERDs), offering a targeted approach to treating hormone receptor-positive breast cancer. We'll discuss how elacestrant works and its potential benefits for patients. Disclaimer: This CZcams channel is not intended to provide diagnosis, treatment, or medical advice. The content provided in this video is ...
Understanding how ACE inhibitors cause coughing │ Pharmacology
zhlédnutí 2,7KPřed 2 měsíci
In this video, we'll break down the science behind ACE inhibitors, how they work to lower blood pressure, and the mechanism that leads to that persistent cough that some people experience. Disclaimer: This CZcams channel is not intended to provide diagnosis, treatment, or medical advice. The content provided in this video is for informational purposes only. This should not be considered as a su...
Hot Flash Relief? Understanding Fezolinetant: A New Option for Menopausal Hot Flashes
zhlédnutí 153Před 3 měsíci
Menopause can present various challenges, including hot flashes, night sweats, mood swings, and sleep disturbances. Fezolinetant, a non-hormonal therapy, has emerged as a promising option for alleviating these symptoms safely and effectively. We'll explore how it works and its effectiveness in managing menopausal symptoms. Disclaimer: This CZcams video is not intended to provide diagnosis, trea...
Olipudase Alfa: Pioneering the Way for Acid Sphingomyelinase Deficiency (ASMD) Treatment
zhlédnutí 92Před 3 měsíci
In this video, we’re going to delve into the revolutionary treatment of Acid Sphingomyelinase Deficiency (ASMD) with olipudase alfa. ASMD, also known as Niemann-Pick Disease type A and B, is a rare and debilitating genetic disorder affecting lipid metabolism. Olipudase alfa, a recombinant human acid sphingomyelinase (ASM), has emerged as a beacon of hope for patients and families affected by th...
Unlocking Sleep: The Science Behind Daridorexant and Its Role in Managing Insomnia
zhlédnutí 130Před 3 měsíci
In this video, we delve into the fascinating world of daridorexant, a novel medication designed to tackle insomnia. Join us as we look into its mechanism of action and how it differs from traditional sleep aids, potential benefits, and side effects. Whether you're struggling with insomnia or simply curious about the latest advancements in sleep medicine, this video provides an overview of darid...
The Fight Against Fabry Disease: New Weapon - Pegunigalsidase Alfa Explained
zhlédnutí 129Před 3 měsíci
Fabry disease, a rare genetic disorder, has found a powerful adversary in Pegunigalsidase Alfa. In this video, learn the basics of Fabry disease: how does it affect the body and what are the symptoms? We will then look into how pegunigalsidase alfa works and a brief run-through of the clinical trial that has paved the way for its approval. Disclaimer: This CZcams video is not intended to provid...
COPD Breakthrough: The Ensifentrine Revolution │ PHARMACOLOGY
zhlédnutí 4,6KPřed 4 měsíci
Update: The FDA has approved ensifentrine (Ohtuvayre; Verona Pharma) for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adult patients (www.veronapharma.com/news/verona-pharma-announces-us-fda-approval-of-ohtuvayre-ensifentrine/). Discover how it works to alleviate the symptoms of COPD, providing a beacon of hope for millions around the world grappling with this re...
Duchenne Muscular Dystrophy: Could Gene Therapy Be the Answer? Exploring SRP-9001
zhlédnutí 1,1KPřed 4 měsíci
Duchenne Muscular Dystrophy: Could Gene Therapy Be the Answer? Exploring SRP-9001
Sickle Cell Hope: Exa-cel - The CRISPR Therapy Making a Difference
zhlédnutí 71Před 5 měsíci
Sickle Cell Hope: Exa-cel - The CRISPR Therapy Making a Difference
Lecanemab: A Beacon of Hope for Alzheimer's Disease
zhlédnutí 244Před 5 měsíci
Lecanemab: A Beacon of Hope for Alzheimer's Disease
Rimegepant: New treatment for migraine attacks
zhlédnutí 502Před 5 měsíci
Rimegepant: New treatment for migraine attacks
Conquer Cholesterol with Bempedoic Acid: A Rising Star in Hyperlipidemia Management
zhlédnutí 217Před 6 měsíci
Conquer Cholesterol with Bempedoic Acid: A Rising Star in Hyperlipidemia Management
Schizophrenia Treatment Revolution? Introducing Xanomeline: Potential and Latest Updates
zhlédnutí 4,1KPřed 6 měsíci
Schizophrenia Treatment Revolution? Introducing Xanomeline: Potential and Latest Updates
Resistant Hypertension: Can Aprocitentan Be the Missing Piece? │ Pharmacology
zhlédnutí 567Před 6 měsíci
Resistant Hypertension: Can Aprocitentan Be the Missing Piece? │ Pharmacology
Unlocking a New Frontier: Aldosterone Synthase Inhibitor for Hypertension (Lorundrostat, Baxdrostat)
zhlédnutí 515Před 6 měsíci
Unlocking a New Frontier: Aldosterone Synthase Inhibitor for Hypertension (Lorundrostat, Baxdrostat)
Breaking the Chains of Refractory Gout: Pegloticase Pharmacology Simplified
zhlédnutí 244Před 6 měsíci
Breaking the Chains of Refractory Gout: Pegloticase Pharmacology Simplified
N-Acetylcysteine & Paracetamol Poisoning Rescue
zhlédnutí 2KPřed 7 měsíci
N-Acetylcysteine & Paracetamol Poisoning Rescue
Exploring the Mechanisms and Applications of Dihydropyridine Calcium Channel Blocker
zhlédnutí 416Před 7 měsíci
Exploring the Mechanisms and Applications of Dihydropyridine Calcium Channel Blocker
ACE Inhibitors in Hypertension Management: Mechanism of Action and Side Effects │ Pharmacology
zhlédnutí 1,3KPřed 7 měsíci
ACE Inhibitors in Hypertension Management: Mechanism of Action and Side Effects │ Pharmacology
How Thiazide Diuretics Lower Blood Pressure: A Simple Explanation
zhlédnutí 263Před 7 měsíci
How Thiazide Diuretics Lower Blood Pressure: A Simple Explanation
How does blood pressure regulation work? │ Physiology
zhlédnutí 96Před 8 měsíci
How does blood pressure regulation work? │ Physiology
Sitagliptin: How It Works to Lower Blood Sugar
zhlédnutí 4,4KPřed 8 měsíci
Sitagliptin: How It Works to Lower Blood Sugar
❤🎉😢
I have severe emphysema I would love to try desperately . I live in Australia Help
Please help me treatment DMD
Please help me treatment DMD
Please help me treatment muscular dystrophy
Easy to understand ❤
theres no reason the manufacturer couldn't include the amino acid in the tablets- except $
My Dr put me on Amlodipine 6mo. Ago and yesterday my legs and feet swelled up for the first time in my life, don’t know why , seems like it would have happen from the start of taking the amlodipine not 6 months Later?
great video bro
Good video thanks
Price
God did not tell us to take brain altering drugs when we have problems. We were told to pray, fast and seek healing from Him and stay clear of things that would polute our minds !
Please help me DMD patient my son
So what is a remedy for this?
Diuretic medicine.
My son is suffering from duchenne muscular dystrophy plz help the child
Pls help me DMD problem 10 years boy 🙏🙏
شكرا ، مبادرة جيدة 🌺
Help me
How about erectile dysfunction?
All the meds are creating a different personality and bad behavior that without the evil poison medication person would never experienced. They medication is worth nothing. You take it if you are so smart...Please take it and you will became schizophrenic. Easy...It is good to say without your own experience. And most of the psychiatrists are quacks. People without heart and compassion.
thank youuuuu this made so much sense
They say it is not good for negative symptoms. And it is not known if it is good for preventing weight gain, there is still a lack of evidence.
Really? Its suppost to be good all around!!! No weight gain or metabolic changes
@@constantinhaller4391 I think the score on the negative symptoms scale was 1.8, similar to olanzapine. There is no clear evidence that it is good for negative symptoms.
@@Roberto11231i see. Ulotaront Hits hard in neg symtoms But not Sure it will Hit the market
yeah I just read in oyou're other comment Ulotaront failed.
@@constantinhaller4391 The difference with placebo was not significant in the score of the negative symptoms subscale.
KarXT
'Promo sm'
I was taking pimozide for two years (2015-2017) for Tourette Syndrome and the effects of emotional flattening (significant) and apathy still remain after 6 years. Could you tell me what happened to me? Does it have a solution or is it permanent?