First line treatment if Motor symptoms are affecting patient’s quality of life: LEVODOPA. It is usually combined with Carbidopa (decarboxylase inhibitor) as this prevents the peripheral metabolism of Levodopa to Dopamine outside the brain (improving CNS bioavailability) and hence can reduce side-effects. Dopamine agonist like Pramipexol, Ropinirole maybe started in younger patients. It may not be as effective as Levodopa but will have few side-effects. Selegiline (MAO-B) is often used to treat early disease and can provide mild symptom relief. COMT inhibitors (Tolcapone, Entacapone) which prevents breakdown of levodopa- are used in combination with Levodopa. Antimuscarinics (Procyclidine, Benzottopine, Benzhexol) are used, mainly for drug induced Parkinsonism. For some patients who do not response to all these measures, Deep Brain Stimulation (DBS) techniques have become the surgical procedure of choice. However, it is very much expensive and is performed by a specialist Neurosurgeon. If you want a full video on Parkinsonism and it’s management - Kindly leave a comment below! Happy Learning 😎🤗
Sir but levodopa causes more damage to neurons in basal ganglia and it is going to be helpful only for max 3 yrs so... Isnt it better to start with dopamine agonists? And why dopamine agonists are not used in old paitents?
Levodopa+Carbidopa to increase dopamine levels in the nigrostriatal pathways in the Basal Ganglia. Can be combined with Bromocriptine as well in some resistant cases of parkinsonism.
1)Mask like face 2)Stooped posture(Rigidity at back and forword flection) 3)Flextion at the elbow 4)Resting tremors in the hand 5)Flextion at the knee 6)Parkinson gait 7)Levodopa is used to cure the motor symptoms
Hi .. I like your videos because they are short and easy pointers. For Parkinson I wanted to know if the posture can be fixed with mild daily exercise or will posture just deteriorate over time?
Levodopa and Carbidopa. Carbidopa crosses BBB but due to increased systemic metabolism of Carbidopa ot is administered with Levodopa which doesn't cross BBB
Start with pramiprexole or ropinirole which are the drug of choice for parkinsonism instead of starting with levodopa +carbidopa combination...am i correct sir?
Can these symptoms be present in stressed person Cz my father have all the symptoms except resting tremor .. I consulted with a doctor, the doctor said it's not Parkinson its becoz of stress ? Is it right sir ? History - my father has been behind the jail for 4 years , he was allegedly made accused in a case ..and his pension funds gratituty is stopped by government..
My mother has same ailments, she's prescribed with syndopa, phendy2, commantrel and saptor c. She's feeling dizzy all the time from this. Don't know what to do... Plz help me out of you can
I don't think so any medicine is going to help sooner or later you will realise with age it will increase but you can control with drugs prescribed by the doctors And I want to add the most important line for you my friend in this process don't let your irritated exhausted hopeless inner come out to your mouth good luck be happy spread happiness
Sir youtube ne notificatoon nahi di aapki video ki agar 2 din pehle di hoti video to mera revise ho jata exam se phele😂kal ke he medicine paper me surprise ques aa gaya tha parkinsonism
First line treatment if Motor symptoms are affecting patient’s quality of life: LEVODOPA.
It is usually combined with Carbidopa (decarboxylase inhibitor) as this prevents the peripheral metabolism of Levodopa to Dopamine outside the brain (improving CNS bioavailability) and hence can reduce side-effects.
Dopamine agonist like Pramipexol, Ropinirole maybe started in younger patients. It may not be as effective as Levodopa but will have few side-effects.
Selegiline (MAO-B) is often used to treat early disease and can provide mild symptom relief.
COMT inhibitors (Tolcapone, Entacapone) which prevents breakdown of levodopa- are used in combination with Levodopa.
Antimuscarinics (Procyclidine, Benzottopine, Benzhexol) are used, mainly for drug induced Parkinsonism.
For some patients who do not response to all these measures, Deep Brain Stimulation (DBS) techniques have become the surgical procedure of choice. However, it is very much expensive and is performed by a specialist Neurosurgeon.
If you want a full video on Parkinsonism and it’s management - Kindly leave a comment below!
Happy Learning 😎🤗
Kindly share the full video on Parkinsonism
Please post full treatment management video
Sir but levodopa causes more damage to neurons in basal ganglia and it is going to be helpful only for max 3 yrs so... Isnt it better to start with dopamine agonists? And why dopamine agonists are not used in old paitents?
Yup
Yes
Please make such shorts for us it is very helpful for us
Yes, will try to upload more such videos 🤗
1) Levodopa and Carbidopa
2) Dopamine agonist like Bromocriptine
3) L-Deprenyl
4) Anticholinergic
Another great video with short and superb explanation.
Levodopa+Carbidopa to increase dopamine levels in the nigrostriatal pathways in the Basal Ganglia. Can be combined with Bromocriptine as well in some resistant cases of parkinsonism.
1)Mask like face
2)Stooped posture(Rigidity at back and forword flection)
3)Flextion at the elbow
4)Resting tremors in the hand
5)Flextion at the knee
6)Parkinson gait
7)Levodopa is used to cure the motor symptoms
Levodopa+ carbodopa ✅👍
Is bexol useful my father is taking that
@@bharathab177 Yes, Bexol can also be used
ok thanks @@Shapalli
Short and informative video for both patients and doctors.
Very useful information u shares everytime ... But plz at end also share line of treatment 👍
Sure dear!
But it is really difficult to include treatment also in 1 min video. Will create another short video on Parkinson’s management!
I love your short videos..they are so informative...pls keep making them. Tahnku😊
Great efforts,, keep it up 👍💪
Thank you so much dear! 🤗
❤ really very much informative... thank you so much Sir.
Benztropine/trihexphenidyll anticholinegics for motor symptoms
Very informative. More such awaited.
Boss, can you upload some of the most common diseases in Opd basis, for junior residents.
Your teaching is a big help.
Methyl dopa + peripheral decarboxylase inhibators (carbidopa,bemserszide) , mao-b inhibitors, com inhibitors , anticholinergics
Kindly make more such videos Sir
Very informative thanks sir
Most welcome dear! 🤗💐
Great effort sir
Thanks a lot dear! 🤗💐
Its very beneficial sir
Thank you so much 😇❤❤❤
Amazing content❤
Helpful content 😊
Combination between levodopa and carbidopa
Thanks Dr
Thank you sir
Namste sir , can u plz share this kind of shorts for CVA pt. !?
It'll be very helpful.
Hi .. I like your videos because they are short and easy pointers. For Parkinson I wanted to know if the posture can be fixed with mild daily exercise or will posture just deteriorate over time?
Levodopa and Carbidopa. Carbidopa crosses BBB but due to increased systemic metabolism of Carbidopa ot is administered with Levodopa which doesn't cross BBB
Sinemet, a combination of levodopa and carbidopa
Levodopa (Dopamine agonist)
Amazing
Very nice🙏🙏
Thanks a lot Prof Angeline 🙏🏻
Good information
Thank you so much dear! 🤗
Big fan of u sir❤
Thank you so much dear for all the Love 🤗❤️
Anticholinergics like- benzhexol, biperidine , procyclidine
Benztropine/trihexphenidyl anticholinegics for motor symptoms
Syndopa.. My mother uses. The lady looks like my mother. I want to hug her. My mother has dementia too😢
Premipex .5/premirol .5 and synodopa plus, and nikoran 5mg
Doc. Levodopa+carbidopa / benserazide
Levodopa and carbodopa along with other drugs whether it's like bromocriptine or central anti cholinergic drugs.
I want full video sir
Shuffling gait wthout arm swing - seen in NPH
Is that possible in Parkinsons also Sir ??
Dolo 650?
Cholenegiscs like levodopa+carbidopa
Start with pramiprexole or ropinirole which are the drug of choice for parkinsonism instead of starting with levodopa +carbidopa combination...am i correct sir?
donepezil and carbidopa-levodopa.. donepezil is known to alleviate non responsiveness to carbidopa.
Sir, when are you starting the usmle course?
Combination of carbidopa and levodopa
Humble request sir ,Kindly , hide identity of the patient. Or write disclaimer regarding patient consent for showing video like this ..
Thanks. .
❤❤
Can these symptoms be present in stressed person
Cz my father have all the symptoms except resting tremor ..
I consulted with a doctor, the doctor said it's not Parkinson its becoz of stress ?
Is it right sir ?
History - my father has been behind the jail for 4 years , he was allegedly made accused in a case ..and his pension funds gratituty is stopped by government..
Make a video on swelling
Levodopa with carbidopa
Bromocryptine mesylate
Artane can be given initially in low dose
❤
Levodopa and carbadopa, because alone levodopa gets oxidised easily
Ok cool, but did you know that mitochondria is the powerhouse of cell.
*of the cell.
You missed “the” in your comment! 😎
❤❤
Treatment is :: Levodopa + carbodopa ✅✅👍
Carvidopa and levodopa
levodopa + carbidopa
My mother has same ailments, she's prescribed with syndopa, phendy2, commantrel and saptor c. She's feeling dizzy all the time from this. Don't know what to do... Plz help me out of you can
I don't think so any medicine is going to help sooner or later you will realise with age it will increase but you can control with drugs prescribed by the doctors
And I want to add the most important line for you my friend in this process don't let your irritated exhausted hopeless inner come out to your mouth good luck be happy spread happiness
Waddling gait 😂
👏
Levodopa and carbidopa
Cortico spinal tracy
Levodopa plus Carbido
U still thr as a icu consultant in neuro deprt in ind Apollo ND
Hi dear.
I left Apollo 1.5 years back. May I know who’s this?
😮❤
❤️💐
Levodopa plus carbidopa
Pramipex 0.5 tds
Levodopa+selegiline
Levadopa &carbadop combination madicine
Levodopa/ Benserazid
Sir youtube ne notificatoon nahi di aapki video ki agar 2 din pehle di hoti video to mera revise ho jata exam se phele😂kal ke he medicine paper me surprise ques aa gaya tha parkinsonism
Saari galti CZcams ki hai 😃😂
Anyways, I hope you have given your best in the exam. Best wishes dear for the result 💐
@@INTELLECTMEDICOS 🙏😊
Levodopa+ carbidopa
Levodopa, gabapentin
Sir they will have ticks
Supreb
Lovodopa with carbidopa
Pill rolling tremor
Levodopa+Carbidopa
Antiparkinson agents- levodopa
Ropenirole
Carbidopa+levodopa
Carvidopa+ levodopa
Levodopa , carbidopa
Levodopa
Tab. Levodopa
Anticholinergics
Carbidopa
Dopamine
levodopa
Levodopamine
Prameprexole
Syndopa levadopa
Marijuana
Dopaminergic drug
Syndopa
Sinamet