Basic Renal Function: Clearance and GFR

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  • čas přidán 9. 09. 2024
  • For tutoring on this topic, click here: lancemillerphd...

Komentáře • 64

  • @lavendershi7071
    @lavendershi7071 Před 4 lety +6

    This serie of videos really help me a lot with the calculation. Thank u very much!

  • @user-zc4cu6rz1d
    @user-zc4cu6rz1d Před 2 lety +5

    1:42 If the substance is reabsorbed and the urine conc. halved, why hasn’t the plasma conc. changed?

  • @shoshohamad9324
    @shoshohamad9324 Před 7 lety +4

    I am from Egypt, thank you very much for the valuable information and the interesting dynamic explanation. Thank you for your great efforts. Thank you

    • @rem2510
      @rem2510 Před 6 lety

      Appreciate video content! Excuse me for butting in, I am interested in your thoughts. Have you ever tried - Trentvorty Perfection Kidney Theorem (just google it)? It is a great one off product for improving kidney function minus the normal expense. Ive heard some super things about it and my BF at very last got cool results with it.

    • @alex-ip1er
      @alex-ip1er Před 6 lety

      Cheers for the Video! Sorry for chiming in, I would appreciate your initial thoughts. Have you researched - Trentvorty Perfection Kidney Theorem (just google it)? It is a smashing one of a kind product for improving kidney function without the normal expense. Ive heard some unbelievable things about it and my close friend Aubrey finally got astronomical results with it.

    • @bondangustariko7282
      @bondangustariko7282 Před 3 lety

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      @denisuprianto2483 Před 3 lety

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  • @xmax700
    @xmax700 Před 3 lety +4

    This war amazing Thank you very much. perfect explain

    • @vladbrad1389
      @vladbrad1389 Před 2 lety

      You're right it's a war it's an amazing war, and we're fighting it 💪

  • @mdabdulhafeezmalik45
    @mdabdulhafeezmalik45 Před 6 lety +2

    Beautyfully explained

  • @nassebella9149
    @nassebella9149 Před 6 měsíci

    Thank you that was helpful ❤

  • @ishaq542
    @ishaq542 Před 11 měsíci +1

    Thank you, sir!

  • @paulafrengul9761
    @paulafrengul9761 Před 7 lety +2

    Very clear and helpful thank you

  • @CristianoRaashid77
    @CristianoRaashid77 Před 3 lety +1

    This was really helpful thank youuu!!!!

  • @Duckguts1
    @Duckguts1 Před 6 lety +1

    Thankyou for best illustrations dey hv saved my time and clear da concept 👍👍👍👍

  • @mariammarello9965
    @mariammarello9965 Před 7 lety +1

    thank you very very much ,, your video is the best

  • @Ahmed_Abdulsattar7
    @Ahmed_Abdulsattar7 Před 2 lety +1

    Amazing
    Thanks bro 🙏

  • @ilovejesus9303
    @ilovejesus9303 Před 6 lety

    Thank you so much for your time, this was helpful

  • @rebornmmmmuch
    @rebornmmmmuch Před 4 lety

    Thanks this really helps💘

  • @user-rb5xz3qu8p
    @user-rb5xz3qu8p Před 3 lety +2

    Awesome

  • @ranadr2788
    @ranadr2788 Před 6 lety

    Very much helpful . Thanks ♡

  • @ahmedelgazar6983
    @ahmedelgazar6983 Před 5 lety

    Thanks a lot for this video💕

  • @danam7172
    @danam7172 Před 5 měsíci

    thank u sm wow

  • @yasasvihasanjana9792
    @yasasvihasanjana9792 Před 6 lety

    Thanks.... clearly explain

  • @leticiamagalhaes3437
    @leticiamagalhaes3437 Před 4 lety

    The volumen of plasma needed to pass through the kidneys in a given amount of time un order to excrete a given quantily of substance in the Urine.

  • @antoniomunaretto9147
    @antoniomunaretto9147 Před 2 měsíci

    i have a question. If the clearance of a substance that is only filtered and not reabsorbed or secreted is equal to the GFR, so 125ml/min. How is that in the first example you made the clearance is only 40?

    • @LanceMillerPhD
      @LanceMillerPhD  Před 2 měsíci +1

      Hi, That's a great question. With the first example of clearance being 40 ml/min, I can see how you have a question and how it does not match with a clearance of 125 ml/min.
      In the first question where the clearance is 40 ml/min, this GFR is well below normal. I used these numbers to illustrate the role of filtration, reabsorption, and secretion on clearance (GFR) rather than illustrating a typical GFR.
      To get a clearance or GFR of 125 ml/min, we could use the following numbers: U = 100 mg/mL, V = 1 ml/min, and P = 0.8 mg/ml. This would give a GFR of 125 ml/min.
      I hope that helps clarify things and sorry for any confusion.
      Best, Dr. Miller

    • @antoniomunaretto9147
      @antoniomunaretto9147 Před 2 měsíci +1

      @@LanceMillerPhD okay now is clear, thank you very much for the clarification.

  • @adityahs2
    @adityahs2 Před 7 lety +1

    do u prepare content from any one particular text books...?
    like berne and levy is what i follow..

  • @rafishikder8110
    @rafishikder8110 Před 2 lety

    THNX

  • @supunjayawardhana3695
    @supunjayawardhana3695 Před 2 lety

    thank you

  • @jamshedfbc
    @jamshedfbc Před 5 lety +1

    Creatine filtered but not reabsorbed or secreted. Where would it go then?

    • @LanceMillerPhD
      @LanceMillerPhD  Před 4 lety +1

      Creatinine is excreted in the urine.

    • @ollanadajikhatikha479
      @ollanadajikhatikha479 Před 3 lety

      Christopher Kenneth's experience of suffering from chronic kidney disease. And how did he deal with it. As you Christopher experiences the fatigue, swollen ankles, sleep deprivation that characterizes CKD sufferers knows that CKD is getting worse - and ultimately causing damage to your body that you can't repair, worrying about the end game for CKD: hours a day on a dialysis machine, kidney transplant. premature death, but she found out from her own doctor that many sufferers have now completely relieved their CKD symptoms. Because CKD is no longer a mystery like it used to be. We now know why it happened - which is why we now know how to stop it in its tracks. For more information click here: tinyurl.com/y5no2zq6?DerNAde7 > ○○○

  • @ghassanauf8103
    @ghassanauf8103 Před 3 lety

    PHD for this !!!!!

  • @fernandofrossard8612
    @fernandofrossard8612 Před 3 lety

    Helpful!

  • @dajanae.d2535
    @dajanae.d2535 Před 3 lety +1

    💝💝💝

  • @mouniraboud9010
    @mouniraboud9010 Před 7 lety +1

    ur the best :) thnx

  • @leahbeechey2898
    @leahbeechey2898 Před 3 lety

    Is clearance & eGFR the same thing?

  • @ScholarIdeavideos
    @ScholarIdeavideos Před 6 lety

    Thanks

  • @lionsinescanor373
    @lionsinescanor373 Před rokem

    very helpful

  • @indira1719
    @indira1719 Před 3 lety

    this was greaaaaat

  • @Gh-ef4yq
    @Gh-ef4yq Před 2 lety +1

    👍

  • @matthewreddick9334
    @matthewreddick9334 Před 6 lety

    Why would a less concentrated plasma yield a higher clearance? seems counterintuitive.

    • @suhaibfarooq3343
      @suhaibfarooq3343 Před 4 lety

      Simply because the plasma is less concentrated, more amount of it will be required to flow through the kidneys to excrete a given amount of solute.

  • @TheSummerOf86
    @TheSummerOf86 Před 7 lety +2

    Awesome, thanks!
    (maybe add 'RPF' and/or 'PAH' to the title)

  • @ranahanna160
    @ranahanna160 Před 6 lety

    a question: if a substance is filtered, how come we have some of it left in the peritubular capillaries to secrete?

    • @LanceMillerPhD
      @LanceMillerPhD  Před 6 lety +11

      That’s a great question. It’s because not all of the fluid and substances that pass through the glomerular capillaries is filtered.

  • @azadparray1659
    @azadparray1659 Před 11 měsíci

    I have creatinine level between 1.1 to 1.25 from last three years now it is 1.23
    Bp is 100/60
    Sugar fasting below 100
    No protein in urine
    USG is normal
    Is there any serious for my kidneys

    • @LanceMillerPhD
      @LanceMillerPhD  Před 11 měsíci

      Your blood pressure and your fasting glucose are great, and the fact that you don’t have protein in the urine and are all positive signs and suggest your kidneys are healthy. Also, your serum creatinine is at the upper end for a male. That’s important to know that serum creatinine is only an estimate of glomerular filtration rate and can vary based on age, gender and muscle mass. as always, this does not replace advice from your physician.

  • @vgvhfgg7385
    @vgvhfgg7385 Před 7 lety

    very nice

  • @birdlynn417
    @birdlynn417 Před 6 lety

    My blood test GFR was 86. Normal is 89 and over. Should I be concerned?

    • @LanceMillerPhD
      @LanceMillerPhD  Před 6 lety

      That is good question and is best answered by your doctor. However, to get a better idea about one thinks about the GFR test, I recommend visiting the following link. www.kidney.org/atoz/content/gfr. The link provides more information about the test, relates values to renal function, and the role of additional tests, i.e., proteinuria, in making a proper diagnosis.
      In summary, a GFR of 86 suggests a mild loss of kidney function (e.g., your kidneys are 86% functional). However, you would have to have your GFR measured for about three months and measure the amount of protein in your urine to make an accurate assessment of renal function (see link). In addition, if your blood pressure is consistently elevated (i.e., >130/80 mm Hg) I would highly recommend you have this checked out sooner rather than later.
      I wish you well and hope that all turns out for the best.

    • @howardrice2470
      @howardrice2470 Před 4 lety

      This is all bs
      I been living for 40 years with less than 50 per cent filtration rate with no problems except doctors. Everybody is different. $$$$ is doctors goal! BS

  • @esha-3296
    @esha-3296 Před 3 lety

    Ei video ta banglay upload kora jayna? 😑

  • @b.s.a.agamer7902
    @b.s.a.agamer7902 Před 5 lety

    Thank you

  • @abuammarali5521
    @abuammarali5521 Před 6 lety

    Thanks