How I distinguish between Lymphocytes vs Monocytes

This is just a brief video and overview on how to differentiate lymphocytes and monocytes morphologically on a peripheral blood smear. I also included blasts just to compare more of their characteristics.
Resources for this channel available on my Amazon storefront:
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Disclosure:
The above link helps run this channel without any additional cost to you.❤️
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Hi I'm Rea! Welcome to my channel, I mainly focus on Hematology where I try to simplify concepts and give memorization techniques, but I do branch out every now and then, and share my life as a Clinical Lab Scientist. Depending on how busy I get, I may get delayed in uploading so please bear with me. I do appreciate the comments and I try to read and reply to them when I can. If you are struggling on a certain topic don't be shy to leave a comment down below, and I'll see what I can do. If my content is helpful for you, come join me and please do like and subscribe! 😊
Thank you for spending your time with me today, and have a nice day! 😁

[@thriftyjenny6291]

I’m in the hematology section of my medical laboratory program. This literally saved my life, so well explained! Tysm :)

[@swiftskii88]

I am literally in the second week of my Hematology Rotation. I’ve been having trouble differentiating these and this video just magically pops up. Thank you!!

[@g-dev324]

This video is straight to the point, thank you so much

[@true_to_who_you_are]

omg this is litteraly saving my life !!! thank you so much 💖

[@JadedbutnotJarred]

This was brilliant! No colleague has explained them to me as well as you have. Please continue making more leukocyte morphology videos!

[@ReaNav]

Thank you for the kind words, these morphology videos are hard because I have to collect pictures for them to be really informative. Thanks! 😊

[@beni10296]

Nice explanation ma'am. I'm gonna use what i've learned here. Thank you very much for this vid.

[@reygtorres4595]

Even for a short video ... I find it helpful. Thank you very much.

[@ReaNav]

Glad you found it helpful. You’re welcome! 😊

[@Catherinefallon17]

Thank you very much!! I have an exam tomorrow, and you explain this so well! There is some subtelities that i didn't realise with my professor and now I see them really well!
Plus, even if i'm french, I understood your explanation very well! Good job, really!

[@ReaNav]

Glad it was helpful! Best of luck! 😊

[@MD-dy8fw]

Awesome video and helpful for sure!

[@Abdulla_K]

Exactly what I was looking for!

[@asifdawar9302]

Great Efforts.Please give us some Lectures on How to identify Malignant Cells in Body Fluids

[@cristinacunha2495]

Your video helped a lot! Thank you very much for your explanation!

[@ReaNav]

You are very welcome.😊

[@ushareddy3173]

Nice video .. clear differentiation

[@Lilia.els.]

Loved this video!

[@edelweisssongvilay2425]

Great explanation!!! Thank u soooo much for this video, this will really help me with my test that i have soon :)

[@Mgsogs]

Great presentation

[@benkay3466]

Nice presentation.Tnx for sharing your knowledge.

[@ReaNav]

You’re welcome! 😊

[@samudrabasu150]

Loved this!!

[@Hemepath]

Thank you so much!!!

[@seokjinnie1158]

Thank you. You save my life

[@la_assassina]

You should have way more views, that was finally some easy explanation :)

[@ReaNav]

Glad you think so, thank you! 😊

[@yangyuexiang1582]

That's so good video! I like it very much since I haven't distinguished them from student till an experienced worker .Looking forward your more amazing video!!

[@ReaNav]

Glad it was helpful! Thanks for the kind words. 😊

[@nasdoc1]

Nice video. Very informative. Thanks.

[@ReaNav]

Glad you enjoyed it!😊

[@marionnyandukomachogu9970]

Thank you 🎉

[@andreatedtaotao2914]

Wow !!! Thank you for this video. I’m in a Hematology Section most of my schedule. Sometimes I’m having a difficulty in identifying with this 3 cell. Now you gave an easier way of identifying it. Maybe you can share IG also the simplest way. Thank you and God bless.

[@ReaNav]

Thanks for your suggestion! I will look into it. 😁

[@minnadahlberg5016]

Great video, thank you so much!

[@ReaNav]

You’re welcome. 😊

[@amanibenk7890]

Thank you so much from Algeria

[@asmaakh3626]

Plz continue it’s to much good 👍🏿 we need more like this video plzzzz

[@asmaakh3626]

More wBc cells

[@angelicadelatorre3077]

Thank you for this ☺️

[@jmy07]

Thank you! ❤

[@bhargavikn4320]

Brilliant video ! Thank you

[@ReaNav]

Glad you enjoyed it!😊

[@miraraaa4306]

Thank you SO much for this

[@ReaNav]

You're welcome! 😊

[@MuhammadYaseen-sp8iq]

Really appreciated great work

[@ReaNav]

Thank you😊

[@helioferreiralopesfilho4477]

Amazing content!

[@ReaNav]

Thank you! 😊

[@kking6777]

Thank you!

[@SaadSaad-mb4py]

Thank you very much

[@hehelium9743]

This video can help me ❤

[@mulengajohnsure7051]

🙏🙏 Thanks...PBS can be nerve wracking for a beginner.

[@samuelhenton3258]

good job!!

[@janelacanaoay6177]

Thank you po 💕

[@OhTheUnknownWolf]

Very helpful thank you so much

[@ReaNav]

Glad it was helpful! 😊

[@hosseinomidrafighdoust243]

Thanks

[@kaungskitchen8908]

I hope more videos about hematology from you.

[@ReaNav]

More to come! 😊

[@arungowtham28]

Great work 👍👍

[@ReaNav]

Thank you so much! 😊

[@sarahgamaleldean3775]

Thanks thanks alot

[@severerevenge8575]

THANK YOU VERY MUCH

[@ReaNav]

You're welcome!😊

[@tyreaslovejr6837]

I've had higher than normal 11+ since 2005 but can anyone tell me what this may indicate?

[@adrianpop4427]

you say at 6:00 that monocytes "don't care about RBC" impling that they don't wrap around them but that's contradicted by the image at 0:35 ( second from the left). Maybe some clarifications would be nice?

[@ReaNav]

I see what you are saying there, on 00:35 notice how the cytoplasm of the monocyte has a lot of vacuolation (lymphs don't have that) and the color gradient of the cytoplasm is even all through out, it's this dirty greyish blue color. If you go to 03:22 (second from left) this is the atypical lymph cytoplasm that wraps around RBC's, notice how you can see a change in color from a clear cytoplasm closer to the nucleus going into an intense darkening on the edges that touches the RBC. The darkening almost looks like a wrapping motion, but when you look at the 00:35 picture you don't get that gradient, it was just a picture of a mono in a crowded area of the smear surrounded by RBC's, also notice the differences in the nucleus size and shape. I hope that clarifies the difference.

[@adrianpop4427]

@@ReaNav Thank you! that helps a lot. I was more unsure about the wraping around part than the other distinguishing features. Also what causes lymphocytes to wrap around RBC ( do they emit pseudopods ? ) ? Thank you again.

[@rinadave354]

Great job 😀

[@ReaNav]

Thanks 😁

[@momori5785]

Thank you so much po ate

[@helenzambrana]

very lovely video. Thank you. :)

[@ReaNav]

You’re welcome! 😊

[@WhatAednaDoes]

thank you!

[@ReaNav]

You are welcome! 😊

[@redanofal4501]

Can you talk about chromatin patterns in both, please

[@poshpink3112]

TYSM!

[@Secondarybh]

Thanks a lot 🌷

[@ReaNav]

You are welcome. 😊

[@chasityswift9125]

Good presentation. I always had trouble distinguishing those until now. Thank you

[@ReaNav]

You are welcome! 😊

[@amkkhan1273]

If blast appear on the slide in which desease

[@MrAbhishekdavid]

thanks

[@ReaNav]

You're welcome! 😊

[@krishnamoorthykg3410]

GOOD KEEP IT UP DEAR

[@ReaNav]

Thank you, I will. 😁

[@070209590]

I am a new dermatologist. I have learned that blast has eyes looking shape.

[@ellyzzasuarez3355]

More videos like this please🥺🥹

[@SaadSaad-mb4py]

Good very good

[@ReaNav]

Thanks! 😊

[@ushareddy3173]

Super

[@righib8886]

Svp pouvez vs traduire cette video en français.can you translate rhis video in franch please?

[@marzopapz1416]

Amazing im starting to love hematology

[@irefusetoputnumbers]

Thanks, this was pretty helpful, but as always in the lab the cells don’t always like to follow the rules 😡

[@Ahmad-tf3mu]

Thank you❤cuteeeeee🎉🎉🎉

[@labbala123]

Mam permission requested to forward this to my students

[@ReaNav]

Of course! 😁

[@kerrybaral9241]

I think all the bast u had them is Myeloblast

[@benibuntu2052]

❤❤❤🙏🙏 😊😊😊👍👍👍

[@divyamsdd5181]

Monocytes are agranular... Then y in the end of the video... U said as monocytes do have granules???
Pls clarify this

[@ReaNav]

Hi, can you please provide time stamps of where the confusion is, it would be easier for me to explain if I knew which parts you need clarification on.

[@divyamsdd5181]

@5.57 granules in monocytes!!????

[@ReaNav]

Hi, there is no need for all the question marks and exclamation points I’ll try my best to walk you through it.😁 At 5:57 I was comparing the cytoplasm of the monocyte and the atypical lymph as you will see the atypical lymph on this slide has a lot clearer cytoplasm compared to the mono which is why I said it is more granulated for a lack of a better term, sorry if that confused you. Which part was the point where I said monocytes were agranular so that I can explain that to you as well.

[@divyamsdd5181]

Thanks for clearing my doubt....
Regarding ur question... We were kept saying dat lymph and monocytes are agranular Ryt?

[@ReaNav]

I don’t believe I said monos are agranular but that is not the main distinguishing factor of monos compared to lymphs. See in the world of these cells there are a lot of characteristics you look out for don’t focus too much on one detail. You have to look at the cells as a whole such as the size of the cytoplasm, the coloring and more so the shape and the size of the nucleus. Try to look at more pictures of these cells, to help you distinguish one from the other, this is as much as I can do for you. I hope this helped, goodluck! ❤️

[@LuckyCharms23]

Our auto slide maker broke and now the manual slide maker makes all lymphs look like blasts 😂😭😓

[@ReaNav]

Aww sorry to hear that, I hope it’s fixed by now. 😆

[@bhagyashriranade3113]

Can you share your contact email I need to send you a pic of a cell I am not being able to distinguish whether it is a lymphocyte or macrophage

[@vegyess]

Bruh i been counting blasts as lymphos

[@ReaNav]

Uh oh. 😅

[@Mtv17950]

Lymphocytes are agranulocytes

[@thechannel4988]

I cant concentrate on the scientific content like my concentration on the pretty smile sounds

[@ReaNav]

Not sure what the pretty smile sounds are but I hope you still got some of the scientific content. hehe.