Immune Tolerance and autoimmunity (overview)

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  • čas přidán 12. 09. 2019
  • this video gives a birds-eye view about the central and peripheral tolerance mechanisms which protects our body from autoimmune cells.

Komentáře • 75

  • @phasespace4700
    @phasespace4700 Před 2 lety +11

    Thanks..this is SO interesting (and helpful). I'd love to see one on a follow up issue: molecular mimicry. Awesome job!

  • @Keithmclane273
    @Keithmclane273 Před 4 lety +6

    You are a hero! thank you!

  • @mj_1258
    @mj_1258 Před rokem

    Thank You my gosh I about flipped w the Lymphocytes reoccurring issue neck. Wow I do have arthritis scoliosis, and neuropathy. Thank You .

  • @mwansakayula34
    @mwansakayula34 Před rokem

    Awesome video

  • @brianbourke75
    @brianbourke75 Před 4 lety +1

    I would love to see a video which reviews of the current techniques in both the lab and clinical to induce antigen specific tolerance.

  • @deej9724
    @deej9724 Před 2 lety +3

    This is brilliant man

  • @odiaclass936
    @odiaclass936 Před 4 lety +1

    Tqu brother...its Amazing

  • @GurleenKaur-ic2li
    @GurleenKaur-ic2li Před 2 lety +1

    Can't take enough for this video 🙏🏻

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 2 lety +2

      Please share my channel link with your friends and help me to reach big audience . Don't forget to check out all my playlist

    • @GurleenKaur-ic2li
      @GurleenKaur-ic2li Před 2 lety +1

      @@animatedbiologywitharpan Okay.👍🏻

  • @jeje2538
    @jeje2538 Před rokem +2

    Thank you so much 🥰

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před rokem

      In order to make high quality content consistently, we need support from you. Please support us by using super thanks option. Super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Small contribution like $5 means a lot for us.

  • @kennedymakumbu9853
    @kennedymakumbu9853 Před 11 měsíci +1

    Thanx alot...powerful presentation😊

  • @LugandaLearner
    @LugandaLearner Před rokem +2

    An awesome lecture..
    Got it better than my Lecturer

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před rokem

      Really glad to know it was useful. Please share my channel with friends. You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

    • @LugandaLearner
      @LugandaLearner Před rokem

      Alright

  • @sreevanisree129
    @sreevanisree129 Před 3 lety +4

    Well explained! Not medical common can also get the concept. Me being a non medical person came to this video because I’m a patient of an auto immune disease and getting treated for the symptoms.
    Got one heavy question for you.
    The question is, autoimmune system causes wide variety of diseases and people reach out to those specialists and get treated for the symptoms. For example a rheumatoid arthritis person reached out to an ortho and they work on suppressing immune system there by ILS. But that’s temporary. How can a person address the root cause? Which specialisation in medicine should they go for and what kind of treatment can they take?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 3 lety +2

      It’s a very interesting question....there are two parts of this question 1) finding the root cause and 2) finding a solution. As our genetic makeup is different from individual to individual there is no common root cause. Diagnosis of the root cause is extremely difficult and costly. Mostly the treatment of autoimmune diseases is temporary suppression of immune system ( with a huge risk of other secondary infection). Long term solution is bone marrow transplant and CRISPR based gene therapy. Unfortunately gene therapy is not available in the market.

  • @toyasinahmed3782
    @toyasinahmed3782 Před rokem +1

    Thank you ❤️

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před rokem

      In order to make high quality content consistently we need support from you. Please support us by using super thanks.
      Small contribution like Rs50/100 means a lot for us.
      super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @lenagh6988
    @lenagh6988 Před 9 měsíci +1

    this is so helpful and simple thank u so much

  • @RituSharma-os3gi
    @RituSharma-os3gi Před 2 lety +1

    so helpful so well explained

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 2 lety

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
      You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @taongaalinani2828
    @taongaalinani2828 Před rokem +1

    nice video😍🥰keep up the good work

  • @tunerd1921
    @tunerd1921 Před 4 lety +1

    Sorry are the central and peripheral mechanisms of B cell tolerance the same then but just differ in their location?

    • @SMass-ey8er
      @SMass-ey8er Před 3 lety

      No thats not correct.
      Bone marrow "central": BcR develop
      Lymph nodes "peripheral": i.e Somatic hypermutation, B-cell maturation into plasma/ memory cell
      antibody class switching...

  • @sujis142
    @sujis142 Před 2 lety +1

    Thankyou 😊

  • @jeroboamminja6295
    @jeroboamminja6295 Před rokem +1

    Good work Broo

  • @__________6597
    @__________6597 Před 3 lety +2

    Nanotecnology medicine is good for kill cancer or infections? Tx

  • @zeynebzaxo4657
    @zeynebzaxo4657 Před rokem +1

    Well done

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před rokem

      Please support my channel via super thanks. Your small contribution like 1$ means a lot for us. The super thanks option is present at the lower right corner of any video, a heart sign with $ in it.

  • @easy_medlife2793
    @easy_medlife2793 Před 3 lety +1

    Great sir

  • @fathimasulaiman5360
    @fathimasulaiman5360 Před 3 lety

    Well explained 👍👍👍👍👍👍

  • @srpmed1138
    @srpmed1138 Před 2 lety +1

    Also watch this: czcams.com/video/U5UJ6x2Neuw/video.html

  • @maryroses826
    @maryroses826 Před 2 lety +1

    Hello friend, my main language is Spanish, for this reason there are some things that I did not understand, could you write me what you said at minute 7:31 until minute 7:36

    • @hudsonprino314
      @hudsonprino314 Před 2 lety

      All thanks to dr udoka on CZcams who help me got rid of my herpes with his herbal remedy,you can reach out to him if you have other disease.

  • @lubukbasung9259
    @lubukbasung9259 Před 3 lety +1

    Good

  • @knowledgejunction1643
    @knowledgejunction1643 Před 4 lety

    Pls uplod also some mcq

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 4 lety +1

      No I don’t do that... I only explain concepts in biology which strengthen basic understanding.... it should not be confused with any Mcq solving tutorial class

    • @knowledgejunction1643
      @knowledgejunction1643 Před 4 lety

      @@animatedbiologywitharpan ohk

  • @nimesh938
    @nimesh938 Před 3 měsíci +1

    ❤❤❤❤❤

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 3 měsíci +1

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 3 měsíci +1

      Suggested video czcams.com/video/a6fPVR3bUuc/video.htmlsi=J1NwuCD-omZ7xTXW

  • @mohamadali3219
    @mohamadali3219 Před 2 lety +1

    Thank you nice
    but i hate those pauses inside the sentences

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 2 lety

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 2 lety

      Thanks for the detailed feedback

  • @Sceneyour
    @Sceneyour Před 8 měsíci +1

    I shouldn't be here but my Micro teacher takes this class way too seriously.

  • @thurgasivaruban2511
    @thurgasivaruban2511 Před rokem +1

    you explained better than my lecturer haha

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před rokem

      Please share my channel link with your friends. Dont foeget to check out the immunology playlist

  • @mateyo8903
    @mateyo8903 Před rokem

    MH-shit😭😂😂

  • @moule945
    @moule945 Před 2 lety +1

    Everything is perfect except your fake foriegn accent..