Mechanism of Action: Transcranial Infrared Photobiomodulation. Is this a Direct or Indirect Therapy?

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  • čas přidán 2. 08. 2023
  • Dr. Theodore Henderson presented at the MGH Brain PBM Clinic Rounds (06.23.23) on the mechanistic pathways of transcranial infrared photobiomodulation, with special emphasis on direct and indirect paths.
    www.massgeneral.org/psychiatr...
    MGHBrainPhotobiomodulation

Komentáře • 54

  • @Gundog55
    @Gundog55 Před 7 měsíci +27

    I was diagnosed with Parkinson’s 3 years ago and participated in an experimental drug program which put from Stage 1 to Stage 3. I withdrew from the program and decided to do my own research. From this I changed my diet, began a Forced Exercise program, purchased an infrared light cap (660nm-980nm) and embraced a strict supplement regime. I lost 29lbs (gained 14 back) all in three months. When I returned to my neurologist she was shocked. She told me that I was better than when she had first seen me and that most people couldn’t of done what I had accomplished. I told her “They could but most won’t, they just want a magic pill.”
    The red light therapy has been very successful for me and even cured a skin disorder from an old chemical burn. When I tell others about it they think I’m crazy so have I quit telling people about it.

    • @SabineNagler
      @SabineNagler Před 7 měsíci +1

      Wow, that's awesome!! Congrats on your achievement. Where did you buy the light cap? Could you share a link?

    • @wSpaceArt
      @wSpaceArt Před 6 měsíci +1

      Thank you for sharing

    • @khlim428
      @khlim428 Před 5 měsíci

      Glad to know your achivement. I would like to know how often and duration you use the treatment? I start to have same problems Thanks

    • @wSpaceArt
      @wSpaceArt Před 5 měsíci +2

      @khlim428 I believe it was more than a treatment. He mentioned diet, supplements, exercises, light therapy, and lost weight (fasting?). Philips has an infrared light device with different models , do 3-4 times a week, @15 mins should be OK. Take care.

    • @denofpigs2575
      @denofpigs2575 Před 4 měsíci

      ​@@khlim428Sugar has a terrible effect on the brain.
      If you're not on antidepressants look at Methylene Blue.
      Also look into fasting and keto. Pottengers Human is a good source.

  • @keithavery3388
    @keithavery3388 Před měsícem +5

    Bell's Theorem explains the penetration phenomenon. Just watched a video that explains this anomaly completely. My guess is the scalp is polarizing the light wave in a manner creating a quantum effect we are only beginning to understand.

    • @laserhobbyist9751
      @laserhobbyist9751 Před 5 dny

      Has anyone considered using high peak short pulse 1064 nm YAG lasers? The average power can be low, such as an inexpensive $500 laser head available now I'm working with which produces 2 watts average power total, but the peak power is 15 kilowatts at 5 ns pulses. At that peak power a lot more of those photons will surely get through without causing heating when the beam is expanded to a large diameter. Also, although perhaps not applicable to the brain, there are high peak power short pulse YAG lasers at 659 nm.
      A out of the box thought I'm having is if these are used on the chest, instead of the head there might be enough wave guide action through the arteries to deliver small amounts of these two wavelengths throughout the brain. Don't let the 15 KW peak power of a small ND:YAG laser scare you away, if expanded to even as little as 100 mm diameter you don't feel it on your skin.
      I'm not sure the .9 Joules of average power per cm (900 milliwatts per second) applies to peak power, perhaps a different amount of light is beneficial when using short nanosecond pulsed peak power per cm2, maybe far less than the .9 Joules minimum that one study produced.

  • @Auggies1956
    @Auggies1956 Před 8 měsíci +20

    If it means anything I was diagnosed with Dementia, a year ago. My most troubling symptom was my speech. I couldn't complete a sentence without forgetting what I was saying. I purchased a Vielight Gama, and within a couple months my speech was almost a hundred percent normal. However my diagnoses was updated to Parkinson's.

    • @foxnorth789
      @foxnorth789 Před 8 měsíci +4

      Don't lose hope! Keep it up and look into stem cells, reverse-aging (David Sinclair), energy modalities to help you recover, etc. I'd increase exercise, other ways to increase blood flow, certain supplements, meditation, tea, sunlight, laughing, smiling, singing, music, etc.

    • @debbiefoster6338
      @debbiefoster6338 Před 7 měsíci

      What wonderful news!! Fantastic to hear. As the other person commented, do check out all the other seemingly simple things that can help you. A ketogenic or carnivore diet with no sugar will definitely benefit Parkinson’s (and a lot of other physical things you never thought could be helped). Also coconut oil and/or MCT (medium chain triglycerides … isolated from coconut oil). Watch CZcams videos from Dr. Lustig, Dr. Chris Palmer, Dr. Ken Berry, Dr. Shawn Baker, Dr. Chaffee and also Dr. Mary Newport. Many of the doctors also have books that discuss Parkinson’s improvements, too. I think brain issues have an array of causes as well as symptoms. Repairing and stimulating circulation and mitochondria have positive cascading effects that continue to improve your health over months and even years. Another couple of things I’d recommend you investigate are brain anti-inflammatories and Hyperbaric Oxygen Treatment (HBOT). My personal experience with my Dad’s dementia is that boswellia extract, Lion’s mane capsules and script Ivrmctn (odd spelling to try to prevent blocking my reply by the thought police) all do an amazing job of reducing swelling and symptoms. Not a cure, but definitely reduce symptoms like agitation, mood swings and poor concentration. Check out Dr. Paul Harch’s CZcams videos on amazing recoveries of severe brain issues using HBOT. Truly astounding cures, but can be expensive and require months of treatments. You can find low-pressure HBOT chambers for $100/dive that don’t require a doctor Rx, or you can rent or even purchase a low-pressure chamber yourself. HBOT increases circulation and oxygen delivery to cells, and helps TBI and PTSD patients, cerebral palsy, MS, Alzheimer’s, as well as diabetic wounds, etc., etc. I pray that our Lord Jesus Christ touch you, heal you and richly bless you. 🙏🏼

    • @wSpaceArt
      @wSpaceArt Před 6 měsíci +4

      Bredesen protocol is good too

    • @nancysdsk
      @nancysdsk Před 5 měsíci +2

      Thank you for sharing your personal story. Hard-won and freely-shared life experience is valuable for me. I hope others will benefit as well. With a good deal if respect I say thank you

    • @ChristineS-lz3mg
      @ChristineS-lz3mg Před 4 měsíci

      Please look into methylene blue

  • @arjenchristianhelder1027
    @arjenchristianhelder1027 Před 11 měsíci +6

    What a fantastic lecture, fascinating and very well presented, thank you very much Dr. Henderson

  • @arjenchristianhelder1027
    @arjenchristianhelder1027 Před 11 měsíci +6

    The real question is what is the actual penetration in a live subject? i cannot imagine the samples used, all dead, albeit fresh, would still have similar optical properties as compared to a living being. Also, just an idea, we know NIR increases the cell charge, could the cells be communicating in a capacitive sense? if the cells have a charge, there is a field, if that field can be modulated by the cell, it could be sensed by cells nearby, this could be a potential communication strategy for the cells. (pure speculation, but worth a shot, this particular question will require some out of the box thinking, perhaps there is a domain yet undiscovered)

  • @SPARTANTRAD3S
    @SPARTANTRAD3S Před 9 měsíci +4

    The remote effect in discussion @ 24:40 mark, can be explained by what is called "Cellular Quantum Tunneling".

    • @yl1487
      @yl1487 Před 5 měsíci

      Thanks for pointing that out. Might you perchance have familiarity with Jim Al-Khalili's research?

  • @jimb728
    @jimb728 Před měsícem +2

    Two issues not answered: with 660 and 850 light, the literature focuses on cytox. What is chromophore for 1064 light? Can brain issues be treated with PBM applied to arms, back, or neck rather than via an expensive helmet or ball cap used to treat the scalp?

  • @peterazlac1739
    @peterazlac1739 Před 5 měsíci +4

    One mechanism that you did not look at was the fascia. - the network of tissue with a high number of nerves cells and the primo vascular blood system that covers and divides muscles and both provides nutrients and signaling molecules but is at the source of proprioception and is linked to the vagus nerve. There is evidence that the points where the fascia penetrates deep into and between muscle tissue is related to the acupuncture points and that manipulating the fascia by pressure affects metabolite levels in the blood. So by using a blood pressure cuff you actually activated the fascia and its effect on blood metabolites.

    • @rodbow66
      @rodbow66 Před 3 měsíci

      What exactly is this? Is this a condition?

    • @myralhf
      @myralhf Před měsícem +1

      Fascia is an amazing important fibrous tissue encasing muscles bones holding all in place with nerves blood connection that moves with tensegricity in all directions...more value than is talked about. Important to keep this fascia covering the whole body hydrated and moving in all directions...to aid muscles, bones, nerve centers, blood flow healthy and functional...from the bottom of your feet to the top of your head and everything in between ... love your body ❤

  • @mickm4577
    @mickm4577 Před měsícem +1

    Great stuff.. Really useful if you could add in the links to the studies referred to

  • @luciavpatterson3389
    @luciavpatterson3389 Před 11 dny

    Maybe it triggers the synthesis of intracellular melatonin and that changes genetic expression and a downstream of beneficial effects

  • @88SunsetStrip
    @88SunsetStrip Před 14 dny +1

    What is the difference in total power or total amount of "infrared photons" that reach the brain when one calculates full sun exposure vs. an inferred helmet over time? This is a HUGE question that needs an answer.

    • @tukity
      @tukity Před 5 dny

      I has the same question. Sun irradiance peaks at 1kw/m^2 or 0.1w/cm^2 =100mw/cm^2 but that's over all spectrums whereas these devices range from 20-250 mw/cm^2 in only the effective wave length. So one can postulate that sunlight isn't nearly as powerful in this regard.

    • @88SunsetStrip
      @88SunsetStrip Před 5 dny

      @@tukity One needs a light meter with a filter that transmits 1070nm light. I'm Sure this is possible. If the power is sufficient, then one could wear a hat with the top of the hat being this filter material. Make this hat and you are in business.

  • @laserhobbyist9751
    @laserhobbyist9751 Před 6 dny

    Has anyone considered using high peak short pulse 1064 nm YAG lasers? The average power can be low, such as an inexpensive $500 laser head available now I'm working with which produces 2 watts average power total, but the peak power is 15 kilowatts at 5 ns pulses. At that peak power a lot more of those photons will surely get through without causing heating when the beam is expanded to a large diameter. Also, although perhaps not applicable to the brain, there are high peak power short pulse YAG lasers at 659 nm.
    A out of the box thought I'm having is if these are used on the chest, instead of the head there might be enough wave guide action through the arteries to deliver small amounts of these two wavelengths throughout the brain. Don't let the 15 KW peak power of a small ND:YAG laser scare you away, if expanded to even as little as 100 mm diameter you don't feel it on your skin.
    I'm not sure the .9 Joules of average power per cm (900 milliwatts per second) applies to peak power, perhaps a different amount of light is beneficial when using short nanosecond pulsed peak power per cm2, maybe far less than the .9 Joules minimum that one study produced.

  • @robertomartinez7268
    @robertomartinez7268 Před 2 měsíci +1

    Both mechanisms might be possible. A blood carried effect mediated by circulating mitochondria, etc..... and, also, an antenna able to receive and intensify the signal. This antenna could be molecular or even supra-molecular (nanocluster).
    This question is the stuff of a researcher dreams.... some lucky postdocs or PhD students are going to have the time of their lives.

  • @titaniumman1201
    @titaniumman1201 Před 7 měsíci +4

    Where did you get the 1064nm lights? These are very hard to find.

    • @donapodaca3729
      @donapodaca3729 Před 11 dny

      Go outside at noon and expose your body to direct sunlight, the more skin the better, for 15-20 minutes 3-4 days/week and get sunrise light into your eyeballs. Sunlight has 1064 in it along with all the other needed wavelengths that these Big Light Pharma providers offer, who are trying to make a living off you. As a mammalian creature on the earth we need UV to NIR and everything in between. Also eat grass fed organic animal products that have healthy fatty acids that include biophotonic energy which is also included in organic & properly processed nuts, seeds, & grains in their oils. It's really quite simple.

  • @wSpaceArt
    @wSpaceArt Před 6 měsíci +3

    Philips Infrared lamp 1000nm, (different models of 100, 150, 300, 650 W) , used at a distance for 15 mins/ time, may be an option for PBM ?

    • @Mazeisaspace
      @Mazeisaspace Před 5 měsíci

      I use the 150w IR-about half an hour

    • @MarkShinnick
      @MarkShinnick Před 3 měsíci

      No, there is no modulating action...requires cyclic pulsing.

    • @Mazeisaspace
      @Mazeisaspace Před 3 měsíci

      @@MarkShinnickthat is contested a lot of IR products don't pulse

  • @InquilineKea
    @InquilineKea Před 8 měsíci

    What wavi eeg helmet

  • @falcon127
    @falcon127 Před 5 měsíci +2

    Well uh, I think uh, we have uh, a complete modality uh, to uh, select uh, a mechanism of uh, a real uh, ... uh

    • @micaonyx5301
      @micaonyx5301 Před 5 měsíci +4

      Try focusing on the information and less on the delivery and you won't really notice 🤔

    • @denofpigs2575
      @denofpigs2575 Před 4 měsíci

      ​@@micaonyx5301Yeah. Never even noticed until he said something because I was so engrossed LOL

    • @donapodaca3729
      @donapodaca3729 Před 11 dny

      falcon is spot on - this Dr. is articulate enough to NOT stammer however he is in a subconscious conflict of conscience due to choosing his profiteering over affordable treatment for people in need. You do NOT need expensive, high-powered lasers to give you what simple sunshine or low cost leds (for specific apps) can provide. Henderson is all about the money.

  • @davidnorman5488
    @davidnorman5488 Před 4 měsíci +3

    You can't talk about it until you can explain the mechanism (the how)??? If that were the case, aspirin wouldn't be on the market. There is a time when the HOW is irrelevant to the WHAT. Elevation is disease and suffering should not have to wait on YOUR level of comfort. Weak.

  • @jeffreyadams648
    @jeffreyadams648 Před 4 měsíci

    This is 48 minutes. People cannot handle this these days. Condense it into 5 minutes! Someone, please.

    • @bwaldners
      @bwaldners Před 3 měsíci +2

      You would learn in proportion!

    • @jaeshasway
      @jaeshasway Před 18 dny +2

      It’s a lecture. Play it when you’re working, relaxing or doing something around the house. There’s no way this type of clinical and scientific research can be condensed into 5 minutes. You will never figure out what’s best if you’re struggling with an ailment that this can help, if you’re looking for 5 min videos. At some point you need to do the research.

    • @teeareijonen6338
      @teeareijonen6338 Před 4 dny

      I agree it was an appropriate length - there was a lot of material discussed which if it had been reduced to 5 minutes would not have allowed the evidence to be presented in a way that allows us to form our own view. 5 minutes would have allowed someone to just state their own opinion. I prefer to see and understand the rationale.