Thyroid Hormone Synthesis

Thyroid hormone synthesis is a complex process involving both intracellular and extracellular components. This 7 min, 43 s video utilizes custom-designed animations and ADA-compliant closed captioning to helps students gain knowledge of this challenging topic. The video was designed to help students visualize the steps in thyroid hormone synthesis, including: 1. Iodide trapping 2. Oxidation of iodide 3. Synthesis of thyroglobulin 4. Iodination of tyrosine 5. Conjugation of T1 and T2 6. Endocytosis and digestion of colloid 7. Secretion of thyroid hormones 8. Conversion of T4 to T3 at target tissues 9.Binding of T3 to nuclear receptors

[@telatti]

this is the best video on thyroid synthesis, thank you! it’s been 6 years and i am always coming back to it when i need to refresh my memory. you did a great job :)

[@benjaminphillip9562]

Permanent cure to hypothyroidism with the help of Dr iyaremoses herbal medication no side effects#driyaremoses channel

[@BrainNP]

Thank you so much for this detailed visual, with an appropriate speaking pace to be able to have time to pause and rewind.

[@dudedude9528]

the way you explained the process is truly amazing god bless you

[@soukainaak2755]

i spend one hour on this course and i was so confused but now u have clarify it on only 7min thank u so much !!

[@bingobangobongo5]

Isn't this just incredible. Imagine the rate at which we can learn this kind of stuff as opposed to the years prior without the internet. The world is at our fingertips!

[@Msimmo35786]

Such a great video! Love your pace and explanation! Thanks!

[@inderpreetsingh5736]

really best video on thyroid synthesis

[@tinaguicoMD]

Very helpful video! It summarizes several paragraphs from the lecture of Thyroid Gland. Thanks.

[@MikaylaMurphy130]

Thank you so much! I has having difficulty understanding this in class and it was explained so clearly here. The animations and pictures were very helpful!

[@sm9828]

absolutely fantastic and descriptive i could not thank you guys enough! much appreciated :D

[@elwynbrooks]

The animation REALLY helps! Thank you!!

[@arunteja1111]

very good video but oxidation of iodine occurs in the lumen as the thyroid peroxidase enzyme present on the apical membrane... iodine is carried to the lumen by the transporter ''pendrin''...then after peroxidase enzyme oxideses the iodine to hypoiodous acid or iodinium.....

[@alidanai8218]

Thank you very much! Simple and Understandable! Good job!

[@hrnairutube]

Excellent animation and clear explanation. Thank you!!

[@GR-bt3et]

EXCELLENT video with great graphics and explanation. I can now say I understand this topic. More like this please!

[@meghnabose3303]

amazing video👍

[@msgenevieveblais]

Honestly you have the best video online for this! Thanks :)
I only wish you would have gone into more detail about why the T3 and T4 need to be processed in the colloid space (as the reaction is very nasty and produces a lot of free radicals and need hydrogen peroxide which would wreak havoc on the cell). It would just help put the vid in perspective as why the rxn does not simply take place in the intracellular space and instead is done extracellularly. But really the vid is perfect thanks! Helped with my tutoring

[@anandmention3173]

so nice no any can explain like u , love from india,

[@fastrack2170]

Thank you very much, it was difficult finding this. I've been taking nascent iodine and I needed to know how the procedure worked.

[@hannakelawala8317]

nice video
thanks for sharing

[@jorgeloroperez5267]

Very well explained! Great work!!

[@manjuprasad.m.k.kempraju2954]

Very good one, thanks for making thyroid understanding easy

[@Homo_sapien30]

Informative, and well explained

[@alisinan9934]

Best thyroid video ever!

[@jacobiniemem1930]

Thank you very much for your detailed information.

[@saraessam6998]

very good animation... thanks

[@12parri]

Great video! Thanks so much!

[@aimansultana6855]

This work is really helpful... thank you !!!

[@erzasarlet6638]

it really helped simplify it!! Tho i study it in french i was able to perfectly understand! thank you very much!!

[@laibashahid9418]

outstanding video!....very helpful!

[@umaribrahim2115]

excellent explanation☺

[@namratakumar4887]

One of the best videos

[@kelseynaidoo9872]

Very informative, thank you.

[@HillsideADAM]

Fantastic video, enjoyed learning about the Thyroid gland #MOT

[@alexanderdavy6205]

Fucking melt

[@jaquelinemanuel5716]

Thank you for a very clear explanation.

[@divyaduggal5950]

Very well explained!

[@yuniee100]

Thank you very much! it is an excellent explanation!!!!

[@RomanEsposito-su3zm]

Best explanation ever thank you!

[@paige0x18]

Thank you so very much for this.

[@channell1104]

Hi ! ,Amazing a wonderful presentation Thanks alot.

[@Drisisv]

such an awesome video. Gracias!!!

[@weissergspritzter]

Great explanation!

[@LegendofA]

Thanks for the explanation!

[@abdullahalmamun9259]

thnx mam... this is really so much helpful for us.

[@hassansoomro126]

very helpful video explain very well!******

[@elixirs4491]

Thank u so much that was so helpful

[@nuveen60]

I am from India. Your video was very helpful in understanding the concept , during my preparation for PG medical entrance exam. Thank you very much

[@kylehallas2011]

nuveen60 good luck

[@lauraedwards7500]

good luck!

[@drvaun81]

nice presentation thanks

[@dontjudgemeok9657]

I'm a 7th grader and i am researching this topic and you did a very good job at explaining the disease

[@zm5887]

Thanks Dr. Metz

[@f3foodfunfacts886]

super and as simple as that,thnk u

[@awaiskhandc4302]

awesome 😊👍👍

[@natalieadams4541]

SO helpful thank you!

[@30musabboouf61]

Thanks alot
Very helpful ❤️

[@aqsaamin7607]

Nicely explained

[@user-kc8ec4no4n]

Excellent, thank you.

[@azkarukanta3668]

Great video! It so much helps :)

[@TheRezhwanDrummer]

well done.

[@nekochan4595]

Helpful^.^
Thank you very much :)

[@alaamekky5840]

great video thank you really

[@blackyrocky7438]

Pendrin transporter transport iodide in to colloid where oxidation of iodide happens by thyroid peroxidase. And thyroid peroxidase also does iodination of thyroglobulin

[@carlospradoguerrero]

Great! Tks a lot!

[@RamanDeep-nt2yr]

thankyou soo much it helped me alott

[@VijayKumar-gu8yn]

Nice ❤️❤️❤️

[@monishkantymondal5527]

so useful❤❤❤

[@levincaritan6855]

omg thank you so much for this!

[@user-oo3fu3ms4o]

Thank you sooo much!!

[@braindots2053]

Thank you so very much.

[@AhmedMD]

Thank you !!!

[@BIZIL91]

Gr8 video

[@nishajaswal5844]

Very helpful

[@user-ju5cz4tb5b]

thanks you very much .

[@janhavikulkarni3440]

Thank you so much...

[@hasnaasalama5535]

aweesooome thaaanks :D

[@varshavarghese8673]

Thank you so much maam.....

[@nehaanshu2597]

Thanks a lot...

[@amayafonseka4171]

Very nice

[@christabelakerele5723]

This is just great! Are the slides available?

[@danielal1100]

Great video! However, the thyroid receptor binds to DNA in the absence of the hormone and leads to transcriptional repression. Once T3 is bound, it causes a conformational change and becomes active, thus, causing transcription to occur.

[@vogelnjreri8248]

It can also bind as an heretodimere with the activated rxr-rezeptor to initiate transscription

[@vogelnjreri8248]

from my medicinal chemistry lecture :D

[@afiicena4705]

really help with my medical study, thank you!!
wish me luck :)

[@user-if9lx9ju5e]

Afifah Mukhliza عفيفه
😂

[@kavyaviswanath9386]

helpful,thank u

[@LiliaDiaz-bl4cx]

thank you!!!!!!!

[@3wordsoxforddaily786]

thank you so much

[@lee11676]

How thyroixine act on the cell?

[@alikimiaei8004]

that was amazing

[@janiesosa647]

thanks for this. I am very visual and just reading and following arrows is not always helpful.

[@mohanned6963]

THANK YOU

[@reenjalal6410]

Thanks for this nice presentation

[@user-if9lx9ju5e]

Reen Jalal الله عليج

[@majolaization]

thank you...

[@GoldenBoy1938]

So with Hashimoto's inflammation of the thyroid gland, this active tissue also breaks down, which means that fewer hormones can be produced and stored, right?

[@user-zl8sz4nq2i]

Thank you so so so.... much

[@hellomeme94]

thanks alot

[@Amurald]

OK..but what happens to the Na+
That enters the parafollicular cell

[@Shacni.]

Good dear💋

[@alikimiaei8004]

thank you

[@yaraelbanna8289]

thank you

[@hadeelsami9107]

thank u ♡♡ u are awesome ♡

[@user-if9lx9ju5e]

Hadeel Sami هلا

[@I34R]

please explain to me what the role of tyrosine is????

[@jayanthsharma2793]

life saver

[@megm2253]

thank u very helpful 😊

[@user-if9lx9ju5e]

meg m hello