Engineering human organs onto a microchip | Dan Huh | TEDxPenn
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- čas přidán 8. 06. 2015
- High costs, animal testing controversies, and long delays of drug development are becoming some of the greatest economical and ethnical challenges we are facing in the 21st century. Dan Huh talks about how bioengineers might be able to circumvent this long-standing problem by using microengineering technologies to build more realistic models of human organs using organ-on-a-chip technology.
As a postdoctoral research fellow at Harvard University’s Wyss Institute, Dan Huh worked with Donald Ingber to develop the first organs-on-chips using microengineering technologies for cell biology. These microchips served as models of human organs. Dan Huh is now a professor in the Department of Bioengineering at the University of Pennsylvania. Dan Huh has authored over 30 papers in Science, Nature, Nature Materials, PNAS, and other major research journals. He has won several honors and awards including the NIH Director’s New Innovator Award, which grants innovators $1.5 million during the next five years to work on groundbreaking technologies.
This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at ted.com/tedx
Thanks sir for sharing amazing idea.
Thanks for sharing this amazing content :)
Cool technology and very inspiring talk with great delivery!! saw this gadget at moma and became fascinated by how it was designed and what it could do. true that it's still years from replacing animal trials but hopeful for the success of this technology.
His presentation is very similar to Geraldine Hamilton's Tedx talks on 2013 except with the eye blinking microchip.
I'm a genetic engineering student and organs on a chip topic is now one of my favorite topic.
Both Geraldine Hamilton and Dan Huh and also their team are amazing!
Hello Eylül! How the researching about organs on a chip are going? I'm a Mechanical Engineering student but I am really deep into medicine and bioengineering topics. I'm devoloping a pneumatic exoskeleton, but I really enjoyed the ideia about working with microfluids chips.
안녕하세요 허동은 교수님. 정말 유익한 강연이었습니다!
Thank you for sharing, Dan Suh! This is brilliant and so exciting. :D
Brilliant
can it be used as a replacement for digestive system?
Lung on a chip is a chip structure modeled after the lung shape, and I learned in detail that lung cells and capillary cells are cultured on it to form organoids. It is very surprising that I can see how the lungs and capillary cells react when you inject certain drugs with this chip. Various chips are still being developed, and if they are further developed in the future, there will be a day when various technologies can be commercialized without animal testing!
can I get treatment for kidney failure by this tissue engineering system? if so would you advise me
It is just not true that animal biology is completely different from humans. The details differs quite a bit, but the general machine is largely conserved. Any drug on the market today is based on knowledge acquired studying animals. Hopefully, one day these organs on chips will also be as successful.
뭐야 바이오칩 한국인이 개발한 거였음? 진짜 대박이네
great lecture. BTW many of the failures in clinical testing are results of poor preclinical testing and development. People try to save money on preclinical testing, and rush into clinical testing.
Chips in human is going cause a curse on your life and family future life be careful with wicked devices
Bestie the chips aren't in humans they're just growing human cells in them
we need a new medical paradigm other than the pharmaceutical solution, everyone wants BETTER drugs, I dont want any drugs, I just want my body to heal itself.
Ok how is that going to happen?
Drugs are based on natural body chemicals. They help the body heal itself, genius.
@@laaarsas the way your ancestors did
@@boran6927 Just a reminder people used to die from catching a cold
@@arielmergold9771 because they did not have vaccine. Our immune system is way better and protects its self, heal itself
America, I'm telling you don't involved in WW3, or even start it for maintaining your hegemony. This will back shift us all atleast by 130 years again. We would lose so so much of discoveries. Let's act civilised and let science continue.
Plz speak EASY TT
oh yeah me too
I think this amazing idea may contribute very much in producing vaccine for covid-19 but these business behind big pharma never let that happen
TED 666
TRUMP ON A CHIP. Be afwaid, be very afwaid!
IM WHEEZING
A real shame that he was the one that did the presentation. It is apparent that this is a very important advancement that might solve the problems he articulated. However, his inconsistent English pronunciations and his making some kind of clicking/smacking sounds with his mouth (a few times a minutes) made for a very distracting presentation. In addition, he didn't create excitement by presenting the challenges and failing of this new approach (so far), so it ended up a very biased presentation.
the click sounds is a mechanical device the presenter is using to change slides.
Jealously burns ha? :))
Robert Winkler You are so mean. English is not a measure of intelligence but a language. He did an awesome job. I am wondering what you have invented that is changing the world with your excellent communication skills. Jeez!
In a work of life that has vast original language-to-adopted language diversity, your observation is remarkable and borne of either ignorance, illiteracy, perception deficiency or some combination thereof. They now publish primary research papers that people can read, try it. Of course, if you're very wealthy and thought this would be the researcher' audition for your funding, hire yourself someone who might understand his very very slight accent to articulate what you should invest in. As a matter of fact, I could transcribe the words he said into clearer format for a fee out of your deep pocket. I promise not to include any hint of sarcasm in my service.